Identification

Namevitex agnus-castus

Regulatory

Physical Properties

Food Chemicals Codex Listed No

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryinformation only not used for fragrances or flavors
Recommendation for vitex agnus-castus usage levels up tonot for fragrance use.
Recommendation for vitex agnus-castus flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

chasteberry

Synonyms

abraham's balm abrahams balm chaste tree chaste-tree chasteberry monk's pepper monks pepper vitex agnus castus PubMed: Herbal medicine for the management of polycystic ovary syndrome (PCOS) and associated oligo/amenorrhoea and hyperandrogenism; a review of the laboratory evidence for effects with corroborative clinical findings. PubMed: Metabolic profiling of Vitex agnus castus leaves, fruits and sprouts: analysis by LC/ESI/(QqQ)MS and (HR) LC/ESI/(Orbitrap)/MS n. PubMed: Comparing the effect of mefenamic Acid and vitex agnus on intrauterine device induced bleeding. PubMed: Complementary and alternative medicine (CAM) use in an Italian cohort of pediatric headache patients: the tip of the iceberg. PubMed: Involvement of histone H3 phosphorylation via the activation of p38 MAPK pathway and intracellular redox status in cytotoxicity of HL-60 cells induced by Vitex agnus-castus fruit extract. PubMed: Quality evaluation of medicinal products and health foods containing chaste berry (Vitex agnus-castus) in Japanese, European and American markets. PubMed: Effects of "vitex agnus castus" extract and magnesium supplementation, alone and in combination, on osteogenic and angiogenic factors and fracture healing in women with long bone fracture. PubMed: Efficacy and safety of Vitex agnus-castus extract for treatment of premenstrual syndrome in Japanese patients: a prospective, open-label study. PubMed: Effects and treatment methods of acupuncture and herbal medicine for premenstrual syndrome/premenstrual dysphoric disorder: systematic review. PubMed: Optimisation of phenolics recovery from Vitex agnus-castus Linn. leaves by high-pressure and temperature extraction. PubMed: The genus Vitex: A review. PubMed: Herbal preparations for the menopause: beyond isoflavones and black cohosh. PubMed: Evaluation of biological and chemical insect repellents and their potential adverse effects. PubMed: Cytotoxicity of Vitex agnus-castus fruit extract and its major component, casticin, correlates with differentiation status in leukemia cell lines. PubMed: The value of complementary and alternative medicine in the treatment of climacteric symptoms: results of a survey among German gynecologists. PubMed: Low potency homeopathic remedies and allopathic herbal medicines: is there an overlap? PubMed: An ethnobotanical study of medicinal plants in Turgutlu (Manisa-Turkey). PubMed: Compounds from the Fruits of the Popular European Medicinal Plant Vitex agnus-castus in Chemoprevention via NADP(H):Quinone Oxidoreductase Type 1 Induction. PubMed: ISPMD consensus on the management of premenstrual disorders. PubMed: Development and validation of a rapid ultra-high performance liquid chromatography diode array detector method for Vitex agnus-castus. PubMed: Possible Modulation of the Anexiogenic Effects of Vitex Agnus-castus by the Serotonergic System. PubMed: Adverse effects of herbal medicines: an overview of systematic reviews. PubMed: Antibacterial activity and composition of essential oils from Pelargonium graveolens L'Her and Vitex agnus-castus L. PubMed: Vitex agnus-castus extracts for female reproductive disorders: a systematic review of clinical trials. PubMed: Dose-dependent efficacy of the Vitex agnus castus extract Ze 440 in patients suffering from premenstrual syndrome. PubMed: Liquid chromatography tandem mass spectrometry determination of chemical markers and principal component analysis of Vitex agnus-castus L. fruits (Verbenaceae) and derived food supplements. PubMed: Use of Vitex agnus-castus in migrainous women with premenstrual syndrome: an open-label clinical observation. PubMed: Trypanocidal and cytotoxic activities of essential oils from medicinal plants of Northeast of Brazil. PubMed: Therapeutic effect of Vitex agnus castus in patients with premenstrual syndrome. PubMed: [Psychic aspects of the premenstrual dysphoric disorders. New therapeutic strategies: our experience with Vitex agnus castus]. PubMed: A new diterpenoid glucoside and two new diterpenoids from the fruit of Vitex agnus-castus. PubMed: Differential attraction of Aedes albopictus in the field to flowers, fruits and honeydew. PubMed: The effects of commercial preparations of herbal supplements commonly used by women on the biotransformation of fluorogenic substrates by human cytochromes P450. PubMed: [Our experience with management of inherited thrombophilia during pregnancy. Preliminary report]. PubMed: Herbal treatments for alleviating premenstrual symptoms: a systematic review. PubMed: Phytoconstituents from Vitex agnus-castus fruits. PubMed: Anti-inflammatory and enzyme inhibitory activities of a crude extract and a pterocarpan isolated from the aerial parts of Vitex agnus-castus. PubMed: Larvicidal activity of selected plant hydrodistillate extracts against the house mosquito, Culex pipiens, a West Nile virus vector. PubMed: Opioidergic mechanisms underlying the actions of Vitex agnus-castus L. PubMed: Medicinal plants as alternative treatments for female sexual dysfunction: utopian vision or possible treatment in climacteric women? PubMed: Therapeutic management of premenstrual syndrome. PubMed: Phytochemistry and nematicidal activity of the essential oils from 8 Greek Lamiaceae aromatic plants and 13 terpene components. PubMed: Evaluating therapeutic effect in symptoms of moderate-to-severe premenstrual syndrome with Vitex agnus castus (BNO 1095) in Chinese women. PubMed: Extraction, separation and isolation of volatiles from Vitex agnus-castus L. (Verbenaceae) wild species of Sardinia, Italy, by supercritical CO2. PubMed: Treatment of moderate to severe premenstrual syndrome with Vitex agnus castus (BNO 1095) in Chinese women. PubMed: Repellency against head lice (Pediculus humanus capitis). PubMed: Antiestrogenic constituents of the Thai medicinal plants Capparis flavicans and Vitex glabrata. PubMed: Three new diterpenoids from the fruit of Vitex agnus-castus. PubMed: Nature helps: from research to products against blood-sucking arthropods. PubMed: Effects of a combination of Hypericum perforatum and Vitex agnus-castus on PMS-like symptoms in late-perimenopausal women: findings from a subpopulation analysis. PubMed: Vitex agnus-castus (Chaste-Tree/Berry) in the treatment of menopause-related complaints. PubMed: Are changes of prolactin levels the effectors of vitex agnus castus beneficial effects on the pre-menstrual syndrome? PubMed: [The premenstrual syndrome: effectiveness of Vitex agnus castus]. PubMed: Isolation and immunomodulatory properties of a flavonoid, casticin from Vitex agnus-castus. PubMed: Vitex agnus-castus. Monograph. PubMed: Treatment for premenstrual syndrome with Vitex agnus castus: A prospective, randomized, multi-center placebo controlled study in China. PubMed: Diagnosing and treating premenstrual syndrome in five western nations. PubMed: Antiinflammatory and lipoxygenase inhibitory compounds from Vitex agnus-castus. PubMed: Vitex agnus castus as prophylaxis for osteopenia after orchidectomy in rats compared with estradiol and testosterone supplementation. PubMed: Plantlet regeneration potential from seedling explants of vitegnus (Vitex agnus castus). PubMed: Cytotoxic effects of flavonoids against a human colon cancer derived cell line, COLO 201: a potential natural anti-cancer substance. PubMed: Five new diterpenoids, viteagnusins A--E, from the fruit of Vitex agnus-castus. PubMed: Selection of woody species for wastewater enhancement and restoration of riparian woodlands. PubMed: In vitro screening for the tumoricidal properties of international medicinal herbs. PubMed: Can Vitex Agnus Castus be Used for the Treatment of Mastalgia? What is the Current Evidence? PubMed: Hypericum perforatum with Vitex agnus-castus in menopausal symptoms: a randomized, controlled trial. PubMed: The antiepileptic activity of Vitex agnus castus extract on amygdala kindled seizures in male rats. PubMed: Gynecological efficacy and chemical investigation of Vitex agnus-castus L. fruits growing in Egypt. PubMed: Insect growth regulatory activity of Vitex trifolia and Vitex agnus-castus essential oils against Spilosoma obliqua. PubMed: The effects of phytoestrogens on fracture healing: experimental research in New Zealand white rabbits. PubMed: Safety and efficacy of chastetree (Vitex agnus-castus) during pregnancy and lactation. PubMed: Reduced reproductive function in wild baboons (Papio hamadryas anubis) related to natural consumption of the African black plum (Vitex doniana). PubMed: The effects of Vitex agnus castus extract and its interaction with dopaminergic system on LH and testosterone in male mice. PubMed: Vitex agnus castus might enrich the pharmacological armamentarium for medical treatment of prolactinoma. PubMed: Antioxidant activity of Vitex agnus-castus L. extracts. PubMed: Diterpenoids and flavonoids from the fruits of Vitex agnus-castus and antioxidant activity of the fruit extracts and their constituents. PubMed: The essential oil composition of Vitex agnus-castus f. rosea leaves and flowers. PubMed: Activation of the mu-opiate receptor by Vitex agnus-castus methanol extracts: implication for its use in PMS. PubMed: A Vitex agnus-castus extract inhibits cell growth and induces apoptosis in prostate epithelial cell lines. PubMed: Vitex agnus-castus is a preferred host plant for Hyalesthes obsoletus. PubMed: Human gastric signet ring carcinoma (KATO-III) cell apoptosis induced by Vitex agnus-castus fruit extract through intracellular oxidative stress. PubMed: Vitex agnus castus: a systematic review of adverse events. PubMed: Extract of the seeds of the plant Vitex agnus castus proven to be highly efficacious as a repellent against ticks, fleas, mosquitoes and biting flies. PubMed: Isolation of linoleic acid as an estrogenic compound from the fruits of Vitex agnus-castus L. (chaste-berry). PubMed: Treatment of cyclical mastalgia with a solution containing a Vitex agnus castus extract: results of a placebo-controlled double-blind study. PubMed: Evidence for estrogen receptor beta-selective activity of Vitex agnus-castus and isolated flavones. PubMed: Glucosides from Vitex agnus-castus. PubMed: Vitex agnus castus essential oil and menopausal balance: a research update [Complementary Therapies in Nursing and Midwifery 8 (2003) 148-154]. PubMed: Chaste tree (Vitex agnus-castus)--pharmacology and clinical indications. PubMed: Fluoxetine versus Vitex agnus castus extract in the treatment of premenstrual dysphoric disorder. PubMed: A preliminary RAPD-PCR analysis of Cimicifuga species and other botanicals used for women's health. PubMed: Cytotoxicity and apoptotic inducibility of Vitex agnus-castus fruit extract in cultured human normal and cancer cells and effect on growth. PubMed: Phytoestrogens: a viable option? PubMed: Vitexagnus-castus essential oil and menopausal balance: a self-care survey. PubMed: [Effectiveness of Vitex agnus-castus preparations]. PubMed: Evaluation of estrogenic activity of plant extracts for the potential treatment of menopausal symptoms. PubMed: Treatment for the premenstrual syndrome with agnus castus fruit extract: prospective, randomised, placebo controlled study. PubMed: Efficacy of Vitex agnus castus L. extract Ze 440 in patients with pre-menstrual syndrome (PMS). PubMed: Pharmacological activities of Vitex agnus-castus extracts in vitro. PubMed: [Treatment of cyclical mastalgia with a solution containing a Vitex agnus castus extract: Results of a placebo-controlled double-blind study. Breast 1999;8:175-181]. PubMed: Quantitative high performance liquid chromatographic analysis of diterpenoids in agni-casti fructus. PubMed: Parameters influencing the yield and composition of the essential oil from Cretan Vitex agnus-castus fruits. PubMed: Treatment of premenstrual syndrome with a phytopharmaceutical formulation containing Vitex agnus castus. PubMed: [Treatment of cyclical mastodynia using an extract of Vitex agnus castus: results of a double-blind comparison with a placebo]. PubMed: Complementary therapy and infertility: an Icelandic perspective. PubMed: Cytotoxic flavonoids from Vitex agnus-castus. PubMed: Treatment of premenstrual tension syndrome with Vitex agnus castus controlled, double-blind study versus pyridoxine. PubMed: Composition of the essential fruit oil of Vitex agnus-castus. PubMed: Multiple follicular development associated with herbal medicine. PubMed: [Vitex agnus castus extract in the treatment of luteal phase defects due to latent hyperprolactinemia. Results of a randomized placebo-controlled double-blind study]. PubMed: Agnus castus extracts inhibit prolactin secretion of rat pituitary cells. PubMed: The chaste tree: Vitex agnus castus. PubMed: [Iridoidführung von Vitex agnus-castus.] PubMed: [Flavonols from Fruits of Vitex agnus castus]. PubMed: [ISOLATION OF HOMO-ORIENTINE FROM THE LEAVES OF VITEX AGNUS CASTUS L]. PubMed: [Flavonoids from Vitex agnus castus L]. PubMed: [Pseudoindican from Vitex agnus castus L].