silybum marianum herb
st. mary's thistle herb
Identification
| Name | silybum marianum herb |
| IUPAC | silybum marianum l. herb |
| CAS Number | 84604-20-6 |
| FDA UNII | Search |
Regulatory
Physical Properties
| Food Chemicals Codex Listed | No |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | intraperitoneal-mouse LD50 681 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | information only not used for fragrances or flavors |
| Recommendation for silybum marianum herb usage levels up to | not for fragrance use. |
| Recommendation for silybum marianum herb flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
lady's
thistle herb
ladys
thistle herb
milk
thistle herb
st. mary's
thistle herb
st. marys
thistle herb
PubMed:
Phylogenetic and chemical diversity of fungal endophytes isolated from Silybum marianum (L) Gaertn. (milk thistle).
PubMed:
The effects of milk thistle (Silybum marianum) on human cytochrome P450 activity.
PubMed:
Cytoprotective effect of silybin against lasalocid-induced toxicity in HepG2 cells.
PubMed:
A systematic approach to evaluate herb-drug interaction mechanisms: investigation of milk thistle extracts and eight isolated constituents as CYP3A inhibitors.
PubMed:
Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence.
PubMed:
Phenotyping studies to assess the effects of phytopharmaceuticals on in vivo activity of main human cytochrome p450 enzymes.
PubMed:
Silibinin inhibits the toxic aggregation of human islet amyloid polypeptide.
PubMed:
Antidiabetic plants of Iran.
PubMed:
Meta-analysis of the effect of herbal supplement on glycemic control in type 2 diabetes.
PubMed:
Identification of novel pregnane X receptor activators from traditional Chinese medicines.
PubMed:
Silibinin: a novel inhibitor of Aβ aggregation.
PubMed:
Assessment of a dry extract from milk thistle (Silybum marianum) for interference with human liver cytochrome-P450 activities.
PubMed:
Patented bioavailability enhancement techniques of silymarin.
PubMed:
Two flavonolignans from milk thistle (Silybum marianum) inhibit CYP2C9-mediated warfarin metabolism at clinically achievable concentrations.
PubMed:
Silibinin prevents amyloid beta peptide-induced memory impairment and oxidative stress in mice.
PubMed:
A systematic review of the potential herbal sources of future drugs effective in oxidant-related diseases.
PubMed:
Clinical assessment of CYP2D6-mediated herb-drug interactions in humans: effects of milk thistle, black cohosh, goldenseal, kava kava, St. John's wort, and Echinacea.
PubMed:
Complementary and alternative medicine use by patients chronically infected with hepatitis C virus.
PubMed:
Clinical applications of Silybum marianum in oncology.
PubMed:
Review of clinical trials evaluating safety and efficacy of milk thistle (Silybum marianum [L.] Gaertn.).
PubMed:
Does Silybum marianum play a role in the treatment of chronic hepatitis C?
PubMed:
Silymarin treatment of viral hepatitis: a systematic review.
PubMed:
Effect of milk thistle (Silybum marianum) and black cohosh (Cimicifuga racemosa) supplementation on digoxin pharmacokinetics in humans.
PubMed:
Herb-drug interactions: a literature review.
PubMed:
In vivo assessment of botanical supplementation on human cytochrome P450 phenotypes: Citrus aurantium, Echinacea purpurea, milk thistle, and saw palmetto.
PubMed:
[Flavonoids: risks or therapeutic opportunities?].
PubMed:
The clinical utility of milk thistle (Silybum marianum) in cirrhosis of the liver.
PubMed:
Milk thistle and the treatment of hepatitis.