sodium citrate dihydrate

2-hydroxy-1,2,3-propane tricarboxylic acid trisodium salt dihydrate

CAS: 6132-04-3 C6 H9 Na3 O9 MW: 294.09983784

Identification

Namesodium citrate dihydrate
IUPACtrisodium 2-hydroxypropane-1,2,3-tricarboxylate dihydrate
CAS Number6132-04-3
FDA UNIIB22547B95K
Molecular FormulaC6 H9 Na3 O9
Molecular Weight294.09983784
MDL NumberMFCD00150031
Nikkaji NumberC13249
Beilstein6104939

Regulatory

FDA/DG SANTE Petitions, Reviews, NoticesEU SANCO
FEMA Number3026
FDANo longer provide for the use of these seven synthetic flavoring substances

Physical Properties

Appearance white powder (est)
Assay 99.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 301.00 to 303.00 °C. @ 760.00 mm Hg
Boiling Point 308.00 to 309.00 °C. @ 760.00 mm Hg
Vapor Pressure 0.000057 mmHg @ 25.00 °C. (est)
Flash Point 311.00 °F. TCC ( 155.00 °C. )
logP (o/w) -1.721 (est)
Shelf Life 12.00 month(s) or longer if stored properly.
Storage store in cool, dry place in tightly sealed containers, protected from heat and light.
Soluble in water

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesbuffering agents

Organoleptic Properties

Odor Strength none
Odor Description at 100.00 %.

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryantioxidants and preservatives for fragrance and flavor
Recommendation for sodium citrate dihydrate usage levels up tonot for fragrance use.
baked goods-
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum-
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products40.00000
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

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Potential Uses

buffering agents chelating agents

Natural Occurrence

not found in nature

Synonyms

citratin citric acid trisodium salt dihydrate citrosodine 2- hydroxy-1,2,3-propane tricarboxylic acid trisodium salt dihydrate 2- hydroxy-1,2,3-propanetricarboxylic acid trisodium salt dihydrate 1,2,3- propanetricarboxylic acid, 2-hydroxy-, sodium salt, hydrate (1:3:2) sodium 2-hydroxy-1,2,3-propanetricarboxylate hydrate (3:1:2) sodium 2-hydroxy-1,2,3-propanetricarboxylate hydrate(3:1:2) sodium 2-hydroxypropane-1,2,3-tricarboxylate hydrate (3:1:2) sodium citrate dihydrate granular sodium citrate dihydrate powder sodium citrate dihydrate USP/EP/JP sodium citrate tribasic dihydrate sodium citrate, dihydrate trisodium 2-hydroxypropane-1,2,3-tricarboxylate dihydrate trisodium citrate dihydrate PubMed: Crystallization and preliminary X-ray analysis of a novel type of lipolytic hydrolase from Bacillus licheniformis. PubMed: Capillary-seeding crystallization and preliminary crystallographic analysis of a solvent-tolerant elastase from Pseudomonas aeruginosa strain K. PubMed: Size-controlled preparation of α-calcium sulphate hemihydrate starting from calcium sulphate dihydrate in the presence of modifiers and the dissolution rate in simulated body fluid. PubMed: Cloning, expression, purification and preliminary X-ray diffraction studies of a mycobacterial protein implicated in bacterial survival in macrophages. PubMed: Rapid determination of nitroimidazole residues in honey by liquid chromatography/tandem mass spectrometry. PubMed: Comparative analysis of stability and toxicity profile of three differently capped gold nanoparticles for biomedical usage. PubMed: Hypoosmotic swelling test in alpaca (Vicugna pacos) epididymal spermatozoa. PubMed: Additive concentration effects on dicalcium phosphate dihydrate cements prepared using monocalcium phosphate monohydrate and hydroxyapatite. PubMed: Analysis of pesticides residues in fresh produce using buffered acetonitrile extraction and aminopropyl cleanup with gas chromatography/triple quadrupole mass spectrometry, liquid chromatography/triple quadrupole mass spectrometry, gas chromatography/ion trap detector mass spectrometry, and GC with a halogen-specific detector. PubMed: New, fast and green procedure for the synthesis of gold nanoparticles based on sonocatalysis. PubMed: Effects of gamma radiation on solid trisodium citrate dihydrate: radical kinetics, radiosensitivity and dosimetry. PubMed: Sodium citrate dihydrate doped with Mn3+ ions. PubMed: Rheological properties of reversible thermo-setting in situ gelling solutions with the methylcellulose-polyethylene glycol-citric acid ternary system (2): Effects of various water-soluble polymers and salts on the gelling temperature. PubMed: Expression, purification, crystallization and preliminary X-ray diffraction studies of triosephosphate isomerase from methicillin-resistant Staphylococcus aureus (MRSA252). PubMed: Comparison of an experimental bone cement with a commercial control, Hydroset. PubMed: Extent of hepatitis E virus elimination is affected by stabilizers present in plasma products and pore size of nanofilters. PubMed: Crystallization and preliminary X-ray diffraction studies of the ISC-like [2Fe-2S] ferredoxin (FdxB) from Pseudomonas putida JCM 20004. PubMed: Crystallization and identification of the glycosylated moieties of two isoforms of the main allergen Hev b 2 and preliminary X-ray analysis of two polymorphs of isoform II. PubMed: Overexpression, purification and crystallization of lysine epsilon-aminotransferase (Rv3290c) from Mycobacterium tuberculosis H37Rv. PubMed: Factors influencing calcium phosphate cement shelf-life. PubMed: Cloning, expression, purification and crystallization of a transcriptional regulatory protein (Rv3291c) from Mycobacterium tuberculosis H37Rv. PubMed: Cloning, expression, purification and crystallization of NHR3 domain from acute myelogenous leukemia-related protein AML1-ETO. PubMed: Ionic modification of calcium phosphate cement viscosity. Part II: hypodermic injection and strength improvement of brushite cement. PubMed: Expression, purification, crystallization and preliminary crystallographic analysis of phosphoserine aminotransferase from Bacillus alcalophilus. PubMed: Effect of sodium citrate on structure-function relationships of Cheddar cheese. PubMed: Synergism between the brushite and hydroxyapatite urinary crystallization inhibitors. PubMed: Artificial insemination with canine semen stored at a low temperature. PubMed: [Determination of 4-aminobutyric acid in pumpkin powder by high performance liquid chromatography]. PubMed: Pseudo gray platelet syndrome in a patient with acute myocardial infarction. PubMed: A novel chromogenic ester agar medium for detection of Salmonellae. PubMed: Experimental model to study sedimentary kidney stones. PubMed: Oral rehydration therapy. PubMed: The hypo-osmotic swelling test for selection of viable sperm for intracytoplasmic sperm injection in men with complete asthenozoospermia. PubMed: Usefulness of ORT in certain special situations of diarrhoeal diseases. PubMed: ORT and ORS: what is the difference? PubMed: Management of acute diarrhea in children: lessons learned. PubMed: Super ORS. PubMed: Treatment of experimental acute uranium poisoning by chelating agents. PubMed: Inhibition of calcium pyrophosphate dihydrate crystal formation: effects of carboxylate ions. PubMed: Citrate can effectively replace bicarbonate in oral rehydration salts for cholera and infantile diarrhoea. PubMed: Dehydration: W.H.O. has a new solution. PubMed: News from WHO's Diarrhoeal Diseases Control Programme. PubMed: Contrasting effects of potassium citrate and sodium citrate therapies on urinary chemistries and crystallization of stone-forming salts. PubMed: A simple method for studying the formation of calcium oxalate.