Identification

Namespearmint herb
IUPACmentha spicata l. herb
CAS Number977002-61-1
FDA UNIISearch

Regulatory

FEMA Number3030
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)977002-61-1 ; SPEARMINT (MENTHA SPICATA L.)
FDA RegulationFDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE

Physical Properties

Food Chemicals Codex Listed No

Organoleptic Properties

Odor Description at 100.00 %.
Taste Description spearmint

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryspices, other natural seasonings and flavorings
Recommendation for spearmint herb usage levels up tonot for fragrance use.
baked goods-
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum-
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

No supplier data available

Potential Uses

None Found

Natural Occurrence

spearmint

Synonyms

mentha crispa mentha spicata mentha viridis spearmint medium spearmint, available as 100% certified organic PubMed: Comparative evaluation of five plant extracts and juices for nanoiron synthesis and application for hexavalent chromium reduction. PubMed: Chemical Composition and In Vitro Antibacterial Activity of Mentha spicata Essential Oil against Common Food-Borne Pathogenic Bacteria. PubMed: Efficacy of Mentha spicata essential oil in suppression of Aspergillus flavus and aflatoxin contamination in chickpea with particular emphasis to mode of antifungal action. PubMed: Role of substituents in cyclodextrin derivatives for enantioselective gas chromatographic separation of chiral terpenoids in the essential oils of Mentha spicata. PubMed: Mentha spicata Essential Oil: Chemical Composition, Antioxidant and Antibacterial Activities against Planktonic and Biofilm Cultures of Vibrio spp. Strains. PubMed: Phylogenetic Analysis of Selected Menthol-Producing Species Belonging to the Lamiaceae Family. PubMed: Encapsulation of Mentha Oil in Chitosan Polymer Matrix Alleviates Skin Irritation. PubMed: Ethnopharmacological Survey of Medicinal Plants Used in Traditional Medicine by the Communities of Mount Hermon, Lebanon. PubMed: Analysis and evaluation of antibacterial effects of new herbal formulas, AP-001 and AP-002, against Escherichia coli O157:H7. PubMed: Determination of heavy metals concentration in traditional herbs commonly consumed in the United Arab Emirates. PubMed: Plants used during pregnancy, childbirth, postpartum and infant healthcare in Palestine. PubMed: Functional analysis of (4S)-limonene synthase mutants reveals determinants of catalytic outcome in a model monoterpene synthase. PubMed: Assessment of polyphenol coated nano zero valent iron for hexavalent chromium removal from contaminated waters. PubMed: Growth performance and antioxidant enzyme activities in rainbow trout (Oncorhynchus mykiss) juveniles fed diets supplemented with sage, mint and thyme oils. PubMed: Evaluation of possible toxic effects of spearmint (Mentha spicata) on the reproductive system, fertility and number of offspring in adult male rats. PubMed: Rhynchophorus ferrugineus midgut cell line to evaluate insecticidal potency of different plant essential oils. PubMed: Next generation sequencing unravels the biosynthetic ability of spearmint (Mentha spicata) peltate glandular trichomes through comparative transcriptomics. PubMed: Levels of some microelements and essential heavy metals in herbal teas in Serbia. PubMed: [Molecular identification of Mentha haplocalyx and Mentha spicata with specific primers multi-PCR system]. PubMed: High-rosmarinic acid spearmint tea in the management of knee osteoarthritis symptoms. PubMed: L-carvone induces p53, caspase 3 mediated apoptosis and inhibits the migration of breast cancer cell lines. PubMed: The association between chromaticity, phenolics, carotenoids, and in vitro antioxidant activity of frozen fruit pulp in Brazil: an application of chemometrics. PubMed: Acaricidal activities against house dust mites of spearmint oil and its constituents. PubMed: Secondary metabolites isolation in natural products chemistry: comparison of two semipreparative chromatographic techniques (high pressure liquid chromatography and high performance thin-layer chromatography). PubMed: [Correlation between the output and composition of essential oil and the level of salicylic acid in mint plants at different ontogenetic stages]. PubMed: Proteomic snapshot of spearmint (Mentha spicata L.) leaf trichomes: a genuine terpenoid factory. PubMed: Effect of Mentha spicata L. and Artemisia campestris extracts on the shelf life and quality of vacuum-packed refrigerated sardine (Sardina pilchardus) fillets. PubMed: Nematicidal activity of mint aqueous extracts against the root-knot nematode Meloidogyne incognita. PubMed: 2,2-Diphenyl-1-picrylhydrazyl as a screening tool for recombinant monoterpene biosynthesis. PubMed: Increased seizure latency and decreased severity of pentylenetetrazol-induced seizures in mice after essential oil administration. PubMed: Direct enantiomeric analysis of Mentha essential oils. PubMed: A survey of insect assemblages responding to volatiles from a ubiquitous fungus in an agricultural landscape. PubMed: Potential anticancer activity of carvone in N2a neuroblastoma cell line. PubMed: Adverse effects of herbal medicines: an overview of systematic reviews. PubMed: Antiemetic activity of volatile oil from Mentha spicata and Mentha × piperita in chemotherapy-induced nausea and vomiting. PubMed: (-)-Carvone: antispasmodic effect and mode of action. PubMed: Antiproliferative activity of flower hexane extract obtained from Mentha spicata associated with Mentha rotundifolia against the MCF7, KB, and NIH/3T3 cell lines. PubMed: Chemical composition and repellency of essential oils from four medicinal plants against Ixodes ricinus nymphs (Acari: Ixodidae). PubMed: Postharvest management affects spearmint and calamint essential oils. PubMed: Fumigant toxicity of plant essential oils against Camptomyia corticalis (Diptera: Cecidomyiidae). PubMed: Allergy to mint (Mentha spicata). PubMed: Antioxidant potential of curry (Murraya koenigii L.) and mint (Mentha spicata) leaf extracts and their effect on colour and oxidative stability of raw ground pork meat during refrigeration storage. PubMed: Hydrodistillation and in situ microwave-generated hydrodistillation of fresh and dried mint leaves: a comparison study. PubMed: Retrospective study of oral lichen planus and allergy to spearmint oil. PubMed: Comparative study of rosmarinic acid content in some plants of Labiatae family. PubMed: Antimicrobial activity of commercially available essential oils against Streptococcus mutans. PubMed: Xanthine oxidase inhibitory activity of the methanolic extracts of selected Jordanian medicinal plants. PubMed: Evaluation of the efficacy of two mouthrinses formulated for the relief of xerostomia of diverse origin in adult subjects. PubMed: Repellent activities of some Labiatae plant essential oils against the saltmarsh mosquito Ochlerotatus caspius (Pallas, 1771) (Diptera: Culicidae). PubMed: HS-SPME-GC×GC-qMS volatile metabolite profiling of Chrysolina herbacea frass and Mentha spp. leaves. PubMed: Chemical composition and larvicidal activity of essential oil from Mentha spicata (Linn.) against three mosquito species. PubMed: Oral rosmarinic acid-enhanced Mentha spicata modulates synovial fluid biomarkers of inflammation in horses challenged with intra-articular LPS. PubMed: In-vivo Antioxidant Effects of Ethyl Acetate Fraction of Mentha spicata L. on 4-Nitroquinoline-1-Oxide Injected Mice. PubMed: Chemical diversity in Mentha spicata: antioxidant and potato sprout inhibition activity of its essential oils. PubMed: Medicinal plants as antiemetics in the treatment of cancer: a review. PubMed: [Effect of spearmint oil on lipopolysaccharide induced emphysema-like changes and expression of matrix metalloproteinase-9]. PubMed: Ethnopharmacological survey of medicinal plants in Maden (Elazig-Turkey). PubMed: Free radical scavenging (DPPH) potential in nine Mentha species. PubMed: Antimicrobial activity of plant essential oils against bacterial and fungal species involved in food poisoning and/or food decay. PubMed: Effect of distillation waste water and plant hormones on spearmint growth and composition. PubMed: Infusions and decoctions of mixed herbs used in folk medicine: synergism in antioxidant potential. PubMed: A flexible loop-type flow modulator for comprehensive two-dimensional gas chromatography. PubMed: Comparative evaluation of garlic extract mouthwash and chlorhexidine mouthwash on salivary Streptococcus mutans count - an in vitro study. PubMed: Antibacterial effects of the essential oils of commonly consumed medicinal herbs using an in vitro model. PubMed: Yield, content, and composition of peppermint and spearmints as a function of harvesting time and drying. PubMed: Effects of oral dosage form and storage period on the antioxidant properties of four species used in traditional herbal medicine. PubMed: An ethnobotanical survey of medicinal plants in Sivrice (Elazığ-Turkey). PubMed: Activities of ten essential oils towards Propionibacterium acnes and PC-3, A-549 and MCF-7 cancer cells. PubMed: Ethnobotanical study of medicinal plants from the Humla district of western Nepal. PubMed: An evidence-based systematic review of spearmint by the natural standard research collaboration. PubMed: Protection against LPS-induced cartilage inflammation and degradation provided by a biological extract of Mentha spicata. PubMed: Chemical composition and larvicidal evaluation of Mentha, Salvia, and Melissa essential oils against the West Nile virus mosquito Culex pipiens. PubMed: Mint essential oil can induce or inhibit potato sprouting by differential alteration of apical meristem. PubMed: Microwave-assisted phase-transfer catalysis for the rapid one-pot methylation and gas chromatographic determination of phenolics. PubMed: [Study on the extraction of total flavonoids from Mentha spicata by ultrasonic method]. PubMed: Ethnopharmacy of Turkish-speaking Cypriots in Greater London. PubMed: Antigenotoxic and antioxidant potential of aqueous fraction of ethanol extract of Mentha spicata (L.) against 4-nitroquinoline-1-oxide-induced chromosome damage in mice. PubMed: Protective effects of solvent fractions of Mentha spicata (L.) leaves evaluated on 4-nitroquinoline-1-oxide induced chromosome damage and apoptosis in mouse bone marrow cells. PubMed: Productivity and quality of volatile oil extracted from Mentha spicata and M. arvensis var. piperascens grown by a hydroponic system using the deep flow technique. PubMed: The effect of Mentha spicata and Eucalyptus camaldulensis essential oils on dental biofilm. PubMed: Spearmint herbal tea has significant anti-androgen effects in polycystic ovarian syndrome. A randomized controlled trial. PubMed: Spearmint plantlet culture system as a means to study secondary metabolism. PubMed: Characterization of the harmful effect of olive mill wastewater on spearmint. PubMed: Disability and functional profiles of patients with myasthenia gravis measured with ICF classification. PubMed: Activation and stabilization of the hydroperoxide lyase enzymatic extract from mint leaves (Mentha spicata) using selected chemical additives. PubMed: Ultrasound-assisted extraction coupled with under vacuum distillation of flavour compounds from spearmint (carvone-rich) plants: Comparison with conventional hydrodistillation. PubMed: Distribution, feeding behavior and control strategies of the exotic land snail Achatina fulica (Gastropoda: Pulmonata) in the northeast of Brazil. PubMed: Nonlinear dynamical analysis of the effect by six stimuli on electroencephalogram. PubMed: Chemical composition of essential oils of Thymus and Mentha species and their antifungal activities. PubMed: Extraction of antioxidants from plants using ultrasonic methods and their antioxidant capacity. PubMed: Nematicidal activity of essential oils and their components against the root-knot nematode. PubMed: Mint oil (Mentha spicata Linn.) offers behavioral radioprotection: a radiation-induced conditioned taste aversion study. PubMed: Spearmint induced hypothalamic oxidative stress and testicular anti-androgenicity in male rats - altered levels of gene expression, enzymes and hormones. PubMed: [Effect of Spearmint oil on inflammation, oxidative alteration and Nrf2 expression in lung tissue of COPD rats]. PubMed: Anti-inflammatory activity of four solvent fractions of ethanol extract of Mentha spicata L. investigated on acute and chronic inflammation induced rats. PubMed: Expression of spearmint limonene synthase in transgenic spike lavender results in an altered monoterpene composition in developing leaves. PubMed: Antinociceptive activity of (-)-carvone: evidence of association with decreased peripheral nerve excitability. PubMed: Microwave hydrodiffusion and gravity, a new technique for extraction of essential oils. PubMed: Toxicity of plant essential oils and their components against Lycoriella ingenua (Diptera: Sciaridae). PubMed: Two new lignans from Mentha spicata L. PubMed: Chewing gum and context-dependent memory: the independent roles of chewing gum and mint flavour. PubMed: Iron and magnesium concentrations of mint accessions (Mentha spp.). PubMed: Structure of limonene synthase, a simple model for terpenoid cyclase catalysis. PubMed: Effect of spearmint (Mentha spicata Labiatae) teas on androgen levels in women with hirsutism. PubMed: In vitro antioxidant activity of Polygonium hyrcanicum, Centaurea depressa, Sambucus ebulus, Mentha spicata and Phytolacca americana. PubMed: Comparison of essential oils from three plants for enhancement of antimicrobial activity of nitrofurantoin against enterobacteria. PubMed: The effect of Mentha spicata Labiatae on uterine tissue in rats. PubMed: Cheilitis caused by contact allergy to anethole in spearmint flavoured toothpaste. PubMed: Correlation between the in vitro antioxidant activity and polyphenol content of aqueous extracts from Bulgarian herbs. PubMed: The efficacy of an herbal medicine, Carmint, on the relief of abdominal pain and bloating in patients with irritable bowel syndrome: a pilot study. PubMed: Identification of monomenthyl succinate in natural mint extracts by LC-ESI-MS-MS and GC-MS. PubMed: [Study of chemical constituents in active parts of Mentha spicata III]. PubMed: Analysis of Indian mint (Mentha spicata) for essential, trace and toxic elements and its antioxidant behaviour. PubMed: Antioxidant activity measured in different solvent fractions obtained from Mentha spicata Linn.: an analysis by ABTS*+ decolorization assay. PubMed: Bactericidal activity of organic extracts from Flourensia cernua DC against strains of Mycobacterium tuberculosis. PubMed: Screening of plants used in Danish folk medicine to treat memory dysfunction for acetylcholinesterase inhibitory activity. PubMed: Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity. PubMed: Influence of autoclaved fungal materials on spearmint (Mentha spicata L.) growth, morphogenesis, and secondary metabolism. PubMed: Use of RAPD and AFLP markers to identify inter- and intraspecific hybrids of Mentha. PubMed: "Zahraa", a Unani multicomponent herbal tea widely consumed in Syria: components of drug mixtures and alleged medicinal properties. PubMed: Effect of Mentha piperita (Labiatae) and Mentha spicata (Labiatae) on iron absorption in rats. PubMed: Functional magnetic resonance imaging study of human olfaction and normal aging. PubMed: Contact allergy in the burning mouth syndrome: a retrospective study on 38 patients. PubMed: Monoterpene metabolism. Cloning, expression, and characterization of (-)-isopiperitenol/(-)-carveol dehydrogenase of peppermint and spearmint. PubMed: Contact allergy to spearmint oil in a patient with oral lichen planus. PubMed: Organization of monoterpene biosynthesis in Mentha. Immunocytochemical localizations of geranyl diphosphate synthase, limonene-6-hydroxylase, isopiperitenol dehydrogenase, and pulegone reductase. PubMed: Antimutagenic activity of spearmint. PubMed: Piperitenone oxide as toxic, repellent, and reproduction retardant toward malarial vector Anopheles stephensi (Diptera: Anophelinae). PubMed: Effects of peppermint teas on plasma testosterone, follicle-stimulating hormone, and luteinizing hormone levels and testicular tissue in rats. PubMed: [Diversity of phytophagous and pathogens and their damage to mints (Mentha)]. PubMed: Analytical procedure for the in-vial derivatization--extraction of phenolic acids and flavonoids in methanolic and aqueous plant extracts followed by gas chromatography with mass-selective detection. PubMed: Suppression of neutrophil recruitment in mice by geranium essential oil. PubMed: Metabolic engineering of monoterpene biosynthesis: two-step production of (+)-trans-isopiperitenol by tobacco. PubMed: Investigation of biochemical and histopathological effects of Mentha piperita Labiatae and Mentha spicata Labiatae on liver tissue in rats. PubMed: Heteromeric geranyl diphosphate synthase from mint: construction of a functional fusion protein and inhibition by bisphosphonate substrate analogs. PubMed: Molecular evaluation of a spearmint mutant altered in the expression of limonene hydroxylases that direct essential oil monoterpene biosynthesis. PubMed: [A study on chemical constituents in the herb of Mentha spicata]. PubMed: Investigation of biochemical and histopathological effects of Mentha piperita L. and Mentha spicata L. on kidney tissue in rats. PubMed: Medicinal and aromatic plant materials as nitrification inhibitors for augmenting yield and nitrogen uptake of Japanese mint (Mentha arvensis L. Var. Piperascens). PubMed: Two new monoterpenoid glycosides from Mentha spicata L. PubMed: Influence of drying on the flavor quality of spearmint (Mentha spicata L.). PubMed: Sensitivity-dependent hierarchical receptor codes for odors. PubMed: Allergic contact dermatitis from Mentha spicata (spearmint). PubMed: Inhibition by the essential oils of peppermint and spearmint of the growth of pathogenic bacteria. PubMed: Different stereoselectivity in the reduction of pulegone by Mentha species. PubMed: Attenuation of benzoyl peroxide-mediated cutaneous oxidative stress and hyperproliferative response by the prophylactic treatment of mice with spearmint (Mentha spicata). PubMed: (3R)-Linalool synthase from Artemisia annua L.: cDNA isolation, characterization, and wound induction. PubMed: Plant compounds that induce polychlorinated biphenyl biodegradation by Arthrobacter sp. strain B1B. PubMed: Mentha x piperita, Mentha spicata and Effects of Their Essential Oils on Meloidogyne in Soil. PubMed: Purification and characterization of an NADPH-cytochrome P450 (cytochrome c) reductase from spearmint (Mentha spicata) glandular trichomes. PubMed: Isolation and characterization of an active-site peptide from a monoterpene cyclase labeled with a mechanism-based inhibitor. PubMed: Monoterpene synthases of Pinus contorta and related conifers. A new class of terpenoid cyclase. PubMed: Irreversible inactivation of monoterpene cyclases by a mechanism-based inhibitor. PubMed: 4S-limonene synthase from the oil glands of spearmint (Mentha spicata). cDNA isolation, characterization, and bacterial expression of the catalytically active monoterpene cyclase. PubMed: Induction and Characterization of a Cytochrome P-450-Dependent Camphor Hydroxylase in Tissue Cultures of Common Sage (Salvia officinalis). PubMed: Production and characterization of polyclonal antibodies in rabbits to 4S-limonene synthase from spearmint (Mentha spicata). PubMed: Purification of 4S-limonene synthase, a monoterpene cyclase from the glandular trichomes of peppermint (Mentha x piperita) and spearmint (Mentha spicata). PubMed: Monoterpene biosynthesis: specificity of the hydroxylations of (-)-limonene by enzyme preparations from peppermint (Mentha piperita), spearmint (Mentha spicata), and perilla (Perilla frutescens) leaves. PubMed: Biochemical and Histochemical Localization of Monoterpene Biosynthesis in the Glandular Trichomes of Spearmint (Mentha spicata). PubMed: A simple method for screening of fresh plant material for glycosidic bound volatile compounds. PubMed: Demonstration that limonene is the first cyclic intermediate in the biosynthesis of oxygenated p-menthane monoterpenes in Mentha piperita and other Mentha species. PubMed: The Genetic Basis for a Third Ketone Group in Mentha Spicata L. PubMed: [Study on mint. 8. The anatomy of Mentha arvensis, Mentha spicata, and the hybrid forms, Mentha gentilis and Mentha dalmatica]. PubMed: PEPPERMINT and spearmint.