beta-tocotrienol
2H-1-benzopyran-6-ol, 3,4-dihydro-2,5,8-trimethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrien-1-yl]-, (2R)-
Identification
| Name | beta-tocotrienol |
| CAS Number | 490-23-3 |
| EINECS | 207-708-0 |
| FDA UNII | CHH810ZM8C |
| Molecular Formula | C28 H42 O2 |
| Molecular Weight | 410.64114000 |
| MDL Number | MFCD09264634 |
| Nikkaji Number | J1.455.586B |
| Beilstein | 043513 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 528.80 °C. @ 760.00 mm Hg (est) |
| Flash Point | 423.00 °F. TCC ( 217.00 °C. ) (est) |
| logP (o/w) | 10.300 (est) |
| Soluble in | water, 1.929e-006 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for beta-tocotrienol usage levels up to | not for fragrance use. |
| Recommendation for beta-tocotrienol flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
2H-1-
benzopyran-6-ol, 3,4-dihydro-2,5,8-trimethyl-2-((3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrienyl)-, (2R)-
2H-1-
benzopyran-6-ol, 3,4-dihydro-2,5,8-trimethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-, [R-(E,E)]-
2H-1-
benzopyran-6-ol, 3,4-dihydro-2,5,8-trimethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrien-1-yl]-, (2R)-
2H-1-
benzopyran-6-ol, 3,4-dihydro-2,5,8-trimethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrienyl]-, (2R)-
(2R)-3,4-
dihydro-2,5,8-trimethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrienyl]-2H-1-benzopyran-6-ol
e-
tocopherol
epsilon-
tocopherol
b-
tocotrienol
D-b-
tocotrienol
e-
tokoferol
(2R)-2,5,8-
trimethyl-2-[(3E,7E)-4,8,12-trimethyltrideca-3,7,11-trien-1-yl]-3,4-dihydro-2H-chromen-6-ol
(2R)-2,5,8-
trimethyl-2-[(3E,7E)-4,8,12-trimethyltrideca-3,7,11-trien-1-yl]chroman-6-ol
(2R)-2,5,8-
trimethyl-2-[(3E,7E)-4,8,12-trimethyltrideca-3,7,11-trienyl]-3,4-dihydrochromen-6-ol
PubMed:
Final report on the safety assessment of Tocopherol, Tocopheryl Acetate, Tocopheryl Linoleate, Tocopheryl Linoleate/Oleate, Tocopheryl Nicotinate, Tocopheryl Succinate, Dioleyl Tocopheryl Methylsilanol, Potassium Ascorbyl Tocopheryl Phosphate, and Tocophersolan.
PubMed:
Antioxidant activities of tocopherols/tocotrienols and lipophilic antioxidant capacity of wheat, vegetable oils, milk and milk cream by using photochemiluminescence.
PubMed:
Antiproliferation and induction of caspase-8-dependent mitochondria-mediated apoptosis by β-tocotrienol in human lung and brain cancer cell lines.
PubMed:
Tocochromanols and carotenoids in sorghum (Sorghum bicolor L.): diversity and stability to the heat treatment.
PubMed:
Tocotrienols in Vellozia gigantea leaves: occurrence and modulation by seasonal and plant size effects.
PubMed:
Serum levels of vitamin E forms and risk of cognitive impairment in a Finnish cohort of older adults.
PubMed:
Vitamin E analyses in seeds reveal a dominant presence of tocotrienols over tocopherols in the Arecaceae family.
PubMed:
Identification of α-tocotrienolquinone epoxides and development of an efficient molecular distillation procedure for quantitation of α-tocotrienol oxidation products in food matrices by high-performance liquid chromatography with diode array and fluorescence detection.
PubMed:
Separation of α-tocotrienol oxidation products and eight tocochromanols by HPLC with DAD and fluorescence detection and identification of unknown peaks by DAD, PBI-EIMS, FTIR, and NMR.
PubMed:
Intake of antioxidants and risk of type 2 diabetes in a cohort of male smokers.
PubMed:
Antioxidant activity and inhibition of lipid peroxidation in germinating seeds of transgenic soybean expressing OsHGGT.
PubMed:
High plasma levels of vitamin E forms and reduced Alzheimer's disease risk in advanced age.
PubMed:
Tocopherols and tocotrienols in wheat genotypes in the HEALTHGRAIN Diversity Screen.
PubMed:
Comprehensive analysis of vitamin E constituents in human plasma by liquid chromatography-mass spectrometry.
PubMed:
A short and convenient chemical route to optically pure 2-methyl chromanmethanols. Total asymmetric synthesis of beta-, gamma-, and delta-tocotrienols.
PubMed:
Tocopherol and tocotrienol content of hazelnut cultivars grown in portugal.
PubMed:
Simultaneous determination of vitamin E homologs in chicken meat by liquid chromatography with fluorescence detection.
PubMed:
Dietary antioxidant intake and risk of type 2 diabetes.
PubMed:
Normal phase high-performance liquid chromatography method for the determination of tocopherols and tocotrienols in cereals.
PubMed:
Effects of commercial processing on levels of antioxidants in oats (Avena sativa L.).
PubMed:
Determination of RS,E/Z-tocotrienols by HPLC.
PubMed:
Palm tocotrienols protect ApoE +/- mice from diet-induced atheroma formation.
PubMed:
Biological activity of vitamin E compounds and natural materials by the resorption-gestation test, and chemical determination of the vitamin E activity in foods and feeds.
PubMed:
The isolation and properties of delta-tocotrienol from Hevea latex.