beta-tocotrienol

2H-1-benzopyran-6-ol, 3,4-dihydro-2,5,8-trimethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrien-1-yl]-, (2R)-

CAS: 490-23-3 C28 H42 O2 MW: 410.64114000

Identification

Namebeta-tocotrienol
CAS Number490-23-3
EINECS207-708-0
FDA UNIICHH810ZM8C
Molecular FormulaC28 H42 O2
Molecular Weight410.64114000
MDL NumberMFCD09264634
Nikkaji NumberJ1.455.586B
Beilstein043513

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 528.80 °C. @ 760.00 mm Hg (est)
Flash Point 423.00 °F. TCC ( 217.00 °C. ) (est)
logP (o/w) 10.300 (est)
Soluble in water, 1.929e-006 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for beta-tocotrienol usage levels up tonot for fragrance use.
Recommendation for beta-tocotrienol flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

barley caraway coconut corn cranberry fennel grape oat rice rosemary rye wheat bran oil

Synonyms

2H-1- benzopyran-6-ol, 3,4-dihydro-2,5,8-trimethyl-2-((3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrienyl)-, (2R)- 2H-1- benzopyran-6-ol, 3,4-dihydro-2,5,8-trimethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-, [R-(E,E)]- 2H-1- benzopyran-6-ol, 3,4-dihydro-2,5,8-trimethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrien-1-yl]-, (2R)- 2H-1- benzopyran-6-ol, 3,4-dihydro-2,5,8-trimethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrienyl]-, (2R)- (2R)-3,4- dihydro-2,5,8-trimethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrienyl]-2H-1-benzopyran-6-ol e- tocopherol epsilon- tocopherol b- tocotrienol D-b- tocotrienol e- tokoferol (2R)-2,5,8- trimethyl-2-[(3E,7E)-4,8,12-trimethyltrideca-3,7,11-trien-1-yl]-3,4-dihydro-2H-chromen-6-ol (2R)-2,5,8- trimethyl-2-[(3E,7E)-4,8,12-trimethyltrideca-3,7,11-trien-1-yl]chroman-6-ol (2R)-2,5,8- trimethyl-2-[(3E,7E)-4,8,12-trimethyltrideca-3,7,11-trienyl]-3,4-dihydrochromen-6-ol PubMed: Final report on the safety assessment of Tocopherol, Tocopheryl Acetate, Tocopheryl Linoleate, Tocopheryl Linoleate/Oleate, Tocopheryl Nicotinate, Tocopheryl Succinate, Dioleyl Tocopheryl Methylsilanol, Potassium Ascorbyl Tocopheryl Phosphate, and Tocophersolan. PubMed: Antioxidant activities of tocopherols/tocotrienols and lipophilic antioxidant capacity of wheat, vegetable oils, milk and milk cream by using photochemiluminescence. PubMed: Antiproliferation and induction of caspase-8-dependent mitochondria-mediated apoptosis by β-tocotrienol in human lung and brain cancer cell lines. PubMed: Tocochromanols and carotenoids in sorghum (Sorghum bicolor L.): diversity and stability to the heat treatment. PubMed: Tocotrienols in Vellozia gigantea leaves: occurrence and modulation by seasonal and plant size effects. PubMed: Serum levels of vitamin E forms and risk of cognitive impairment in a Finnish cohort of older adults. PubMed: Vitamin E analyses in seeds reveal a dominant presence of tocotrienols over tocopherols in the Arecaceae family. PubMed: Identification of α-tocotrienolquinone epoxides and development of an efficient molecular distillation procedure for quantitation of α-tocotrienol oxidation products in food matrices by high-performance liquid chromatography with diode array and fluorescence detection. PubMed: Separation of α-tocotrienol oxidation products and eight tocochromanols by HPLC with DAD and fluorescence detection and identification of unknown peaks by DAD, PBI-EIMS, FTIR, and NMR. PubMed: Intake of antioxidants and risk of type 2 diabetes in a cohort of male smokers. PubMed: Antioxidant activity and inhibition of lipid peroxidation in germinating seeds of transgenic soybean expressing OsHGGT. PubMed: High plasma levels of vitamin E forms and reduced Alzheimer's disease risk in advanced age. PubMed: Tocopherols and tocotrienols in wheat genotypes in the HEALTHGRAIN Diversity Screen. PubMed: Comprehensive analysis of vitamin E constituents in human plasma by liquid chromatography-mass spectrometry. PubMed: A short and convenient chemical route to optically pure 2-methyl chromanmethanols. Total asymmetric synthesis of beta-, gamma-, and delta-tocotrienols. PubMed: Tocopherol and tocotrienol content of hazelnut cultivars grown in portugal. PubMed: Simultaneous determination of vitamin E homologs in chicken meat by liquid chromatography with fluorescence detection. PubMed: Dietary antioxidant intake and risk of type 2 diabetes. PubMed: Normal phase high-performance liquid chromatography method for the determination of tocopherols and tocotrienols in cereals. PubMed: Effects of commercial processing on levels of antioxidants in oats (Avena sativa L.). PubMed: Determination of RS,E/Z-tocotrienols by HPLC. PubMed: Palm tocotrienols protect ApoE +/- mice from diet-induced atheroma formation. PubMed: Biological activity of vitamin E compounds and natural materials by the resorption-gestation test, and chemical determination of the vitamin E activity in foods and feeds. PubMed: The isolation and properties of delta-tocotrienol from Hevea latex.