aspartate protease

aspartic protease derived from the flowers of cynera cardunculus l.

Identification

Nameaspartate protease

Regulatory

FDA/DG SANTE Petitions, Reviews, NoticesGRN 34

Physical Properties

Food Chemicals Codex Listed No

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryprocessing aids
Recommendation for aspartate protease usage levels up tonot for fragrance use.
Recommendation for aspartate protease flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

aspartate protease PMC

Synonyms

aspartic protease derived from the flowers of cynera cardunculus l. aspartic proteases aspartic proteinase derived from aspergillus oryzae carrying a gene encoding aspartic proteinase from rhizomucor miehei PubMed: Structure of a presenilin family intramembrane aspartate protease. PubMed: Alterations in membrane-associated CD14 expression and the simultaneous liberation of soluble CD14 fragment in adherent macrophages mediated by a leukocyte carboxyl/aspartate protease. PubMed: Cloning and sequencing of a gene for Mucor rennin, an aspartate protease from Mucor pusillus. PubMed: A novel aspartate protease gene, ALP56, is related to morphological features of colorectal adenomas. PubMed: Cathepsins of lepidopteran insects: Aspects and prospects. PubMed: Purification and characterization of an extracellular aspartate protease from Phycomyces blakesleeanus. PubMed: [Identification, cloning and characterization of the gene for the secretory aspartate protease of Candida albicans]. PubMed: Identification of altered metabolic pathways of γ-irradiated rice mutant via network-based transcriptome analysis. PubMed: Towards rice bran protein utilization: In silico insight on the role of oryzacystatins in biologically-active peptide production. PubMed: Fragment-based designing for the generation of novel leads against BACE1. PubMed: Apogossypolone inhibits the proliferation of LNCaP cells in vitro and in vivo. PubMed: Altered amyloid precursor protein processing regulates glucose uptake and oxidation in cultured rodent myotubes. PubMed: Subcellular compartmentalization of TNF receptor-1 and CD95 signaling pathways. PubMed: Expression profile of genes as indicators of developmental competence and quality of in vitro fertilization and somatic cell nuclear transfer bovine embryos. PubMed: Caspase-2 maintains bone homeostasis by inducing apoptosis of oxidatively-damaged osteoclasts. PubMed: Human herpesvirus 8 interleukin-6 contributes to primary effusion lymphoma cell viability via suppression of proapoptotic cathepsin D, a cointeraction partner of vitamin K epoxide reductase complex subunit 1 variant 2. PubMed: Antiproliferative activity of methanolic extracts from two green algae, Enteromorpha intestinalis and Rizoclonium riparium on HeLa cells. PubMed: Intestinal aspartate proteases TiCatD and TiCatD2 of the haematophagous bug Triatoma infestans (Reduviidae): sequence characterisation, expression pattern and characterisation of proteolytic activity. PubMed: Squeezers and leaf-cutters: differential diversification and degeneration of the venom system in toxicoferan reptiles. PubMed: Alternaria fungus induces the production of GM-CSF, interleukin-6 and interleukin-8 and calcium signaling in human airway epithelium through protease-activated receptor 2. PubMed: Effect of poloxamer 407 administration on the serum lipids profile, anxiety level and protease activity in the heart and liver of mice. PubMed: Recognition of fungal protease activities induces cellular activation and eosinophil-derived neurotoxin release in human eosinophils. PubMed: Proteolytic processing of connective tissue growth factor in normal ocular tissues and during corneal wound healing. PubMed: Ethanol and acetonitrile induces conformational changes in porcine pepsin at alkaline denatured state. PubMed: Human eosinophil innate response to Alternaria fungus through protease-activated receptor-2. PubMed: Cathepsin D is released after severe tissue trauma in vivo and is capable of generating C5a in vitro. PubMed: Therapeutic potential of HIV protease-activable CASP3. PubMed: Phylogenetic analysis of Rice tungro bacilliform virus ORFs revealed strong correlation between evolution and geographical distribution. PubMed: Extensive post-translational processing of potato tuber storage proteins and vacuolar targeting. PubMed: Loss of the extraproteasomal ubiquitin receptor Rings lost impairs ring canal growth in Drosophila oogenesis. PubMed: Lysosomal peptidases and glycosidases in rheumatoid arthritis. PubMed: In vitro metabolism of human and salmon calcitonins in rat liver and kidney evaluated by liquid chromatography-tandem mass spectrometry. PubMed: An increase in cytosolic protease activity during liver preservation. Inhibition by glutathione and glycine. PubMed: Gene expression of proteolytic systems and growth regulators of skeletal muscle in horses with myopathy associated with pituitary pars intermedia dysfunction. PubMed: Biochemical entities that influence membrane-associated TNF RII (80-kDa) and IL-1 RI (80-kDa) complex expression and receptor fragment production in adherent vascular endothelium. PubMed: Overexpression of rice (Oryza sativa L.) OsCDR1 leads to constitutive activation of defense responses in rice and Arabidopsis. PubMed: Intracellular IL-15 controls mast cell survival. PubMed: Biochemical mechanisms that interact with membrane-associated IL-1 RII (60-kDa decoy) receptors in populations of adherent macrophages and vascular endothelium. PubMed: A mechanism of TNFR type II (75 kDa) "shedding" in macrophages. PubMed: Can't live without them, can live with them: roles of caspases during vital cellular processes. PubMed: Cathepsin D links TNF-induced acid sphingomyelinase to Bid-mediated caspase-9 and -3 activation. PubMed: Effect of a human immunodeficiency virus protease inhibitor on human monocyte function. PubMed: Sequence-specific (1)H, (13)C and (15)N resonance assignments and secondary structure of a truncated protease from Simian Foamy Virus. PubMed: Inactivation of cysteine and serine proteases by singlet oxygen. PubMed: Imaging of proteolytic activity using a conditional cell surface receptor. PubMed: Cathepsin D is present in human eccrine sweat and involved in the postsecretory processing of the antimicrobial peptide DCD-1L. PubMed: Gastric antibacterial efficiency is different for pepsin A and C. PubMed: Activation of multiple pathways during photoreceptor apoptosis in the rd mouse. PubMed: Cathepsin D is involved in the regulation of transglutaminase 1 and epidermal differentiation. PubMed: Differential expression of putative cell death regulator genes in near-isogenic, resistant and susceptible barley lines during interaction with the powdery mildew fungus. PubMed: Biochemical alteration of membrane-associated IL-6 RI (80-kDa) in adherent macrophages and vascular endothelium. PubMed: Relative abundance and inhibitory distribution of protease inhibitors in potato juice from cv. Elkana. PubMed: Organophosphorus compound-induced apoptosis in SH-SY5Y human neuroblastoma cells. PubMed: Apaf1 and the apoptotic machinery. PubMed: Beating the malaria parasite at its own game. PubMed: A metallo-dependent cysteine proteinase of Cryptosporidium parvum associated with the surface of sporozoites. PubMed: HIV protease inhibitors: effects on viral maturation and physiologic function in macrophages. PubMed: Molecular cloning and characterization of deoxyuridine triphosphatase from feline immunodeficiency virus (FIV). PubMed: The propeptide is required for in vivo formation of stable active yeast proteinase A and can function even when not covalently linked to the mature region. PubMed: Effects of ATP, vanadate, and molybdate on cathepsin D-catalyzed proteolysis. PubMed: The effect of Vibrio alginolyticus infection on caspase-3 expression and activity in white shrimp Litopenaeus vannamei. PubMed: Expanding the scope of the acyl-type radical addition reactions promoted by SmI2. PubMed: Infection of HEp2 epithelial cells with Candida albicans: adherence and postadherence events. PubMed: Specific inactivation of cysteine protease-type cathepsin by singlet oxygen generated from naphthalene endoperoxides. PubMed: Characterization of the protease domain of Rice tungro bacilliform virus responsible for the processing of the capsid protein from the polyprotein. PubMed: Epidermal differentiation: the role of proteases and their inhibitors. PubMed: Human BACE forms dimers and colocalizes with APP. PubMed: Involvement of cathepsin B in the motor neuron degeneration of amyotrophic lateral sclerosis. PubMed: Caspase cleavage of the transcription factor FLI-1 during preB leukemic cell death. PubMed: Secretases as therapeutic targets for the treatment of Alzheimer's disease. PubMed: Fine characterization of the antigenic site within the flap region in the protease protein of HIV-1. PubMed: Structural biology of allergens. PubMed: Induction of G1 arrest and selective growth inhibition by lactacystin in human umbilical vein endothelial cells. PubMed: Cathepsin D targeted by acid sphingomyelinase-derived ceramide. PubMed: Promotion of heat-induced apoptosis in FM3A cells by protease inhibitors. PubMed: Enhancement of hyperthermic killing in L5178Y cells by protease inhibitors. PubMed: Proteases and Their Involvement in the Infection and Immobilization of Nematodes by the Nematophagous Fungus Arthrobotrys oligospora. PubMed: Reversible activation-inactivation of renin in human plasma.