aspartate protease
aspartic protease derived from the flowers of cynera cardunculus l.
Identification
| Name | aspartate protease |
Regulatory
| FDA/DG SANTE Petitions, Reviews, Notices | GRN 34 |
Physical Properties
| Food Chemicals Codex Listed | No |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | processing aids |
| Recommendation for aspartate protease usage levels up to | not for fragrance use. |
| Recommendation for aspartate protease flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
aspartic protease derived from the flowers of cynera cardunculus l.
aspartic proteases
aspartic proteinase derived from aspergillus oryzae carrying a gene encoding aspartic proteinase from rhizomucor miehei
PubMed:
Structure of a presenilin family intramembrane aspartate protease.
PubMed:
Alterations in membrane-associated CD14 expression and the simultaneous liberation of soluble CD14 fragment in adherent macrophages mediated by a leukocyte carboxyl/aspartate protease.
PubMed:
Cloning and sequencing of a gene for Mucor rennin, an aspartate protease from Mucor pusillus.
PubMed:
A novel aspartate protease gene, ALP56, is related to morphological features of colorectal adenomas.
PubMed:
Cathepsins of lepidopteran insects: Aspects and prospects.
PubMed:
Purification and characterization of an extracellular aspartate protease from Phycomyces blakesleeanus.
PubMed:
[Identification, cloning and characterization of the gene for the secretory aspartate protease of Candida albicans].
PubMed:
Identification of altered metabolic pathways of γ-irradiated rice mutant via network-based transcriptome analysis.
PubMed:
Towards rice bran protein utilization: In silico insight on the role of oryzacystatins in biologically-active peptide production.
PubMed:
Fragment-based designing for the generation of novel leads against BACE1.
PubMed:
Apogossypolone inhibits the proliferation of LNCaP cells in vitro and in vivo.
PubMed:
Altered amyloid precursor protein processing regulates glucose uptake and oxidation in cultured rodent myotubes.
PubMed:
Subcellular compartmentalization of TNF receptor-1 and CD95 signaling pathways.
PubMed:
Expression profile of genes as indicators of developmental competence and quality of in vitro fertilization and somatic cell nuclear transfer bovine embryos.
PubMed:
Caspase-2 maintains bone homeostasis by inducing apoptosis of oxidatively-damaged osteoclasts.
PubMed:
Human herpesvirus 8 interleukin-6 contributes to primary effusion lymphoma cell viability via suppression of proapoptotic cathepsin D, a cointeraction partner of vitamin K epoxide reductase complex subunit 1 variant 2.
PubMed:
Antiproliferative activity of methanolic extracts from two green algae, Enteromorpha intestinalis and Rizoclonium riparium on HeLa cells.
PubMed:
Intestinal aspartate proteases TiCatD and TiCatD2 of the haematophagous bug Triatoma infestans (Reduviidae): sequence characterisation, expression pattern and characterisation of proteolytic activity.
PubMed:
Squeezers and leaf-cutters: differential diversification and degeneration of the venom system in toxicoferan reptiles.
PubMed:
Alternaria fungus induces the production of GM-CSF, interleukin-6 and interleukin-8 and calcium signaling in human airway epithelium through protease-activated receptor 2.
PubMed:
Effect of poloxamer 407 administration on the serum lipids profile, anxiety level and protease activity in the heart and liver of mice.
PubMed:
Recognition of fungal protease activities induces cellular activation and eosinophil-derived neurotoxin release in human eosinophils.
PubMed:
Proteolytic processing of connective tissue growth factor in normal ocular tissues and during corneal wound healing.
PubMed:
Ethanol and acetonitrile induces conformational changes in porcine pepsin at alkaline denatured state.
PubMed:
Human eosinophil innate response to Alternaria fungus through protease-activated receptor-2.
PubMed:
Cathepsin D is released after severe tissue trauma in vivo and is capable of generating C5a in vitro.
PubMed:
Therapeutic potential of HIV protease-activable CASP3.
PubMed:
Phylogenetic analysis of Rice tungro bacilliform virus ORFs revealed strong correlation between evolution and geographical distribution.
PubMed:
Extensive post-translational processing of potato tuber storage proteins and vacuolar targeting.
PubMed:
Loss of the extraproteasomal ubiquitin receptor Rings lost impairs ring canal growth in Drosophila oogenesis.
PubMed:
Lysosomal peptidases and glycosidases in rheumatoid arthritis.
PubMed:
In vitro metabolism of human and salmon calcitonins in rat liver and kidney evaluated by liquid chromatography-tandem mass spectrometry.
PubMed:
An increase in cytosolic protease activity during liver preservation. Inhibition by glutathione and glycine.
PubMed:
Gene expression of proteolytic systems and growth regulators of skeletal muscle in horses with myopathy associated with pituitary pars intermedia dysfunction.
PubMed:
Biochemical entities that influence membrane-associated TNF RII (80-kDa) and IL-1 RI (80-kDa) complex expression and receptor fragment production in adherent vascular endothelium.
PubMed:
Overexpression of rice (Oryza sativa L.) OsCDR1 leads to constitutive activation of defense responses in rice and Arabidopsis.
PubMed:
Intracellular IL-15 controls mast cell survival.
PubMed:
Biochemical mechanisms that interact with membrane-associated IL-1 RII (60-kDa decoy) receptors in populations of adherent macrophages and vascular endothelium.
PubMed:
A mechanism of TNFR type II (75 kDa) "shedding" in macrophages.
PubMed:
Can't live without them, can live with them: roles of caspases during vital cellular processes.
PubMed:
Cathepsin D links TNF-induced acid sphingomyelinase to Bid-mediated caspase-9 and -3 activation.
PubMed:
Effect of a human immunodeficiency virus protease inhibitor on human monocyte function.
PubMed:
Sequence-specific (1)H, (13)C and (15)N resonance assignments and secondary structure of a truncated protease from Simian Foamy Virus.
PubMed:
Inactivation of cysteine and serine proteases by singlet oxygen.
PubMed:
Imaging of proteolytic activity using a conditional cell surface receptor.
PubMed:
Cathepsin D is present in human eccrine sweat and involved in the postsecretory processing of the antimicrobial peptide DCD-1L.
PubMed:
Gastric antibacterial efficiency is different for pepsin A and C.
PubMed:
Activation of multiple pathways during photoreceptor apoptosis in the rd mouse.
PubMed:
Cathepsin D is involved in the regulation of transglutaminase 1 and epidermal differentiation.
PubMed:
Differential expression of putative cell death regulator genes in near-isogenic, resistant and susceptible barley lines during interaction with the powdery mildew fungus.
PubMed:
Biochemical alteration of membrane-associated IL-6 RI (80-kDa) in adherent macrophages and vascular endothelium.
PubMed:
Relative abundance and inhibitory distribution of protease inhibitors in potato juice from cv. Elkana.
PubMed:
Organophosphorus compound-induced apoptosis in SH-SY5Y human neuroblastoma cells.
PubMed:
Apaf1 and the apoptotic machinery.
PubMed:
Beating the malaria parasite at its own game.
PubMed:
A metallo-dependent cysteine proteinase of Cryptosporidium parvum associated with the surface of sporozoites.
PubMed:
HIV protease inhibitors: effects on viral maturation and physiologic function in macrophages.
PubMed:
Molecular cloning and characterization of deoxyuridine triphosphatase from feline immunodeficiency virus (FIV).
PubMed:
The propeptide is required for in vivo formation of stable active yeast proteinase A and can function even when not covalently linked to the mature region.
PubMed:
Effects of ATP, vanadate, and molybdate on cathepsin D-catalyzed proteolysis.
PubMed:
The effect of Vibrio alginolyticus infection on caspase-3 expression and activity in white shrimp Litopenaeus vannamei.
PubMed:
Expanding the scope of the acyl-type radical addition reactions promoted by SmI2.
PubMed:
Infection of HEp2 epithelial cells with Candida albicans: adherence and postadherence events.
PubMed:
Specific inactivation of cysteine protease-type cathepsin by singlet oxygen generated from naphthalene endoperoxides.
PubMed:
Characterization of the protease domain of Rice tungro bacilliform virus responsible for the processing of the capsid protein from the polyprotein.
PubMed:
Epidermal differentiation: the role of proteases and their inhibitors.
PubMed:
Human BACE forms dimers and colocalizes with APP.
PubMed:
Involvement of cathepsin B in the motor neuron degeneration of amyotrophic lateral sclerosis.
PubMed:
Caspase cleavage of the transcription factor FLI-1 during preB leukemic cell death.
PubMed:
Secretases as therapeutic targets for the treatment of Alzheimer's disease.
PubMed:
Fine characterization of the antigenic site within the flap region in the protease protein of HIV-1.
PubMed:
Structural biology of allergens.
PubMed:
Induction of G1 arrest and selective growth inhibition by lactacystin in human umbilical vein endothelial cells.
PubMed:
Cathepsin D targeted by acid sphingomyelinase-derived ceramide.
PubMed:
Promotion of heat-induced apoptosis in FM3A cells by protease inhibitors.
PubMed:
Enhancement of hyperthermic killing in L5178Y cells by protease inhibitors.
PubMed:
Proteases and Their Involvement in the Infection and Immobilization of Nematodes by the Nematophagous Fungus Arthrobotrys oligospora.
PubMed:
Reversible activation-inactivation of renin in human plasma.