hops beta acids
Identification
| Name | hops beta acids |
Regulatory
| FDA/DG SANTE Petitions, Reviews, Notices | GRN 63 |
Physical Properties
| Appearance | white to pale yellow powder (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | antimicrobial agents |
| Recommendation for hops beta acids usage levels up to | not for fragrance use. |
| Recommendation for hops beta acids flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
hops beta acids
PubMed:
Inhibition of fructan-fermenting equine faecal bacteria and Streptococcus bovis by hops (Humulus lupulus L.) β-acid.
PubMed:
Quantitative genetic parameters for yield, plant growth and cone chemical traits in hop (Humulus lupulus L.).
PubMed:
In vitro and in vivo antioxidant and antimutagenic activities of polyphenols extracted from hops (Humulus lupulus L.).
PubMed:
Hexahydro-β-acids potently inhibit 12-O-tetradecanoylphorbol 13-acetate-induced skin inflammation and tumor promotion in mice.
PubMed:
Metabolism of hop-derived bitter acids.
PubMed:
Beer and beer compounds: physiological effects on skin health.
PubMed:
Xanthohumol ameliorates atherosclerotic plaque formation, hypercholesterolemia, and hepatic steatosis in ApoE-deficient mice.
PubMed:
Comparative proteomic profiling in compatible and incompatible interactions between hop roots and Verticillium albo-atrum.
PubMed:
Empiric mathematical model for predicting the content of alpha-acids in hop (Humulus lupulus L.) cv. Aurora.
PubMed:
Isoprene synthase genes form a monophyletic clade of acyclic terpene synthases in the TPS-B terpene synthase family.
PubMed:
Effects of extracts of Humulus lupulus (hops) and Yucca schidigera applied alone or in combination with monensin on rumen fermentation and microbial populations in vitro.
PubMed:
Identification and quantification of the oxidation products derived from α-acids and β-acids during storage of hops ( Humulus lupulus L.).
PubMed:
Comparative analysis of production and purification of homo- and hetero-polysaccharides produced by lactic acid bacteria.
PubMed:
On the reaction of lupulones, hops β-acids, with 1-hydroxyethyl radical.
PubMed:
Hop bitter acids inhibit tumorigenicity of hepatocellular carcinoma cells in vitro.
PubMed:
The effects of beta acids from hops (Humulus lupulus) on mortality of Varroa destructor (Acari: Varroidae).
PubMed:
Effects of hop varieties on ruminal fermentation and bacterial community in an artificial rumen (rusitec).
PubMed:
Isolation of bitter acids from hops (Humulus lupulus L.) using countercurrent chromatography.
PubMed:
HlPT-1, a membrane-bound prenyltransferase responsible for the biosynthesis of bitter acids in hops.
PubMed:
Flavonoid production in transgenic hop (Humulus lupulus L.) altered by PAP1/MYB75 from Arabidopsis thaliana L.
PubMed:
Survival of Escherichia coli O157:H7 in meat product brines containing antimicrobials.
PubMed:
LC determination of luteolin-7-O-β-D-glucoside and apigenin-7-O-β-D-glucoside in rat plasma after administration of Humulus scandens extract and its application to pharmacokinetic studies.
PubMed:
Occurrence of odorant polyfunctional thiols in the Super Alpha Tomahawk hop cultivar. Comparison with the thiol-rich Nelson Sauvin bitter variety.
PubMed:
High-performance liquid chromatographic determination and pharmacokinetic study of apigenin-7-O-β-D-glucoside in rat plasma after intravenous administration.
PubMed:
Chicken intestine microbiota following the administration of lupulone, a hop-based antimicrobial.
PubMed:
Application of plant-based antimicrobials for the growth inhibition of clostridia in pressed beet pulp silage.
PubMed:
Evaluation of genetic variability of wild hops (Humulus lupulus L.) in Canada and the Caucasus region by chemical and molecular methods.
PubMed:
Evaluation of brining ingredients and antimicrobials for effects on thermal destruction of Escherichia coli O157:H7 in a meat model system.
PubMed:
Effects of hops (Humulus lupulus L.) extract on volatile fatty acid production by rumen bacteria.
PubMed:
Transport of hop bitter acids across intestinal Caco-2 cell monolayers.
PubMed:
Identification of new phase II metabolites of xanthohumol in rat in vivo biotransformation of hop extracts using high-performance liquid chromatography electrospray ionization tandem mass spectrometry.
PubMed:
Crystal structure and substrate specificity of plant adenylate isopentenyltransferase from Humulus lupulus: distinctive binding affinity for purine and pyrimidine nucleotides.
PubMed:
Rho iso-alpha acids from hops inhibit the GSK-3/NF-kappaB pathway and reduce inflammatory markers associated with bone and cartilage degradation.
PubMed:
Hop bitter acids efficiently block inflammation independent of GRalpha, PPARalpha, or PPARgamma.
PubMed:
Xanthohumol from hop (Humulus lupulus L.) is an efficient inhibitor of monocyte chemoattractant protein-1 and tumor necrosis factor-alpha release in LPS-stimulated RAW 264.7 mouse macrophages and U937 human monocytes.
PubMed:
Identification and RP-HPLC-ESI-MS/MS quantitation of bitter-tasting beta-acid transformation products in beer.
PubMed:
Capillary zone electrophoresis method for determination of bitter (alpha- and beta-) acids in hop (Humulus lupulus L.) cone extracts.
PubMed:
Control of Listeria monocytogenes on frankfurters by dipping in hops beta acids solutions.
PubMed:
Hop proanthocyanidins induce apoptosis, protein carbonylation, and cytoskeleton disorganization in human colorectal adenocarcinoma cells via reactive oxygen species.
PubMed:
LC-MS/MS quantitation of hop-derived bitter compounds in beer using the ECHO technique.
PubMed:
Antilisterial activity of hops beta acids in broth with or without other antimicrobials.
PubMed:
Terpene biosynthesis in glandular trichomes of hop.
PubMed:
Structural basis of human pregnane X receptor activation by the hops constituent colupulone.
PubMed:
Development of a screening assay for ligands to the estrogen receptor based on magnetic microparticles and LC-MS.
PubMed:
Protective effect of hop beta-acids on microbial degradation of thick juice during storage.
PubMed:
Studying the structural properties of polyalanine and polyglutamine peptides.
PubMed:
Constitutive expression of a grapevine stilbene synthase gene in transgenic hop (Humulus lupulus L.) yields resveratrol and its derivatives in substantial quantities.
PubMed:
NMR assignment of iso-alpha-acids from isomerised extracts of Humulus lupulus L. cones.
PubMed:
Chemopreventive effects of lupulone, a hop {beta}-acid, on human colon cancer-derived metastatic SW620 cells and in a rat model of colon carcinogenesis.
PubMed:
Relevance of organic farming and effect of climatological conditions on the formation of alpha-acids, beta-acids, desmethylxanthohumol, and xanthohumol in hop (Humulus lupulus L.).
PubMed:
Sensitive electrochemical detection method for alpha-acids, beta-acids and xanthohumol in hops (Humulus lupulus L.).
PubMed:
Evidence that the beta-acids fraction of hops reduces central GABAergic neurotransmission.
PubMed:
Sedating effects of Humulus lupulus L. extracts.
PubMed:
Analysis of hop acids and their oxidized derivatives and iso-alpha-acids in beer by capillary electrophoresis-electrospray ionization mass spectrometry.
PubMed:
Characterization of the methanolic extract of hops using capillary electrophoresis-electrospray ionization-mass spectrometry.
PubMed:
Isohumulones modulate blood lipid status through the activation of PPAR alpha.
PubMed:
Generation of organic acids and monosaccharides by hydrolytic and oxidative transformation of food processing residues.
PubMed:
Direct characterization of bitter acids in a crude hop extract by liquid chromatography-atmospheric pressure chemical ionization mass spectrometry.
PubMed:
Mechanisms of cancer chemoprevention by hop bitter acids (beer aroma) through induction of apoptosis mediated by Fas and caspase cascades.
PubMed:
Antiviral activity of hop constituents against a series of DNA and RNA viruses.
PubMed:
Inhibition of peroxynitrite-mediated LDL oxidation by prenylated flavonoids: the alpha,beta-unsaturated keto functionality of 2'-hydroxychalcones as a novel antioxidant pharmacophore.
PubMed:
Formation and accumulation of alpha-acids, beta-acids, desmethylxanthohumol, and xanthohumol during flowering of hops (Humulus lupulus L.).
PubMed:
Comparative chemical attributes of native North American hop, Humulus lupulus var. lupuloides E. Small.
PubMed:
Mechanism for formation of the lightstruck flavor in beer revealed by time-resolved electron paramagnetic resonance.
PubMed:
Cloning and analysis of valerophenone synthase gene expressed specifically in lupulin gland of hop (Humulus lupulus L.).
PubMed:
Phlorisovalerophenone synthase, a novel polyketide synthase from hop (Humulus lupulus L.) cones.
PubMed:
The effect of colupulone (a HOPS beta-acid) on hepatic cytochrome P-450 enzymatic activity in the rat.
PubMed:
A modified TnphoA useful for single-stranded DNA sequencing.
PubMed:
Factors affecting antibacterial activity of hop compounds and their derivatives.
PubMed:
Slippery runs, shifty stops, backward steps, and forward hops: -2, -1, +1, +2, +5, and +6 ribosomal frameshifting.