Identification

Namesceletium tortuosum

Regulatory

Physical Properties

Food Chemicals Codex Listed No

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryinformation only not used for fragrances or flavors
Recommendation for sceletium tortuosum usage levels up tonot for fragrance use.
Recommendation for sceletium tortuosum flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

sceletium tortuosum

Synonyms

channa kanna kougoed PubMed: Proof-of-Concept Randomized Controlled Study of Cognition Effects of the Proprietary Extract Sceletium tortuosum (Zembrin) Targeting Phosphodiesterase-4 in Cognitively Healthy Subjects: Implications for Alzheimer's Dementia. PubMed: A toxicological safety assessment of a standardized extract of Sceletium tortuosum (Zembrin(®)) in rats. PubMed: GC-MS, LC-MS(n), LC-high resolution-MS(n), and NMR studies on the metabolism and toxicological detection of mesembrine and mesembrenone, the main alkaloids of the legal high "Kanna" isolated from Sceletium tortuosum. PubMed: Effects of Sceletium tortuosum in rats. PubMed: Acute effects of Sceletium tortuosum (Zembrin), a dual 5-HT reuptake and PDE4 inhibitor, in the human amygdala and its connection to the hypothalamus. PubMed: A novel approach in herbal quality control using hyperspectral imaging: discriminating between Sceletium tortuosum and Sceletium crassicaule. PubMed: A randomized, double-blind, parallel-group, placebo-controlled trial of Extract Sceletium tortuosum (Zembrin) in healthy adults. PubMed: Forensic analysis of mesembrine alkaloids in Sceletium tortuosum by nonaqueous capillary electrophoresis mass spectrometry. PubMed: In vitro permeation of mesembrine alkaloids from Sceletium tortuosum across porcine buccal, sublingual, and intestinal mucosa. PubMed: Pharmacological actions of the South African medicinal and functional food plant Sceletium tortuosum and its principal alkaloids. PubMed: The effects of Sceletium tortuosum in an in vivo model of psychological stress. PubMed: Investigations of the phytochemical content of Sceletium tortuosum following the preparation of "Kougoed" by fermentation of plant material. PubMed: Review on plants with CNS-effects used in traditional South African medicine against mental diseases.