poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, (3350 mol EO average molar ratio)

CAS: 25322-68-3

Identification

Namepeg-3350
CAS Number25322-68-3
FDA UNIISearch

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 1e+006 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral Toxicityintravenous-dog LDLo 3000 mg/kg
Dermal Toxicitysubcutaneous-mouse LD50 18000 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'KIDNEY, URETER, AND BLADDER: HEMATURIA\nVASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION\nCARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION)']

Safety in Use

Categoryinformation only not used for fragrances or flavors
Recommendation for peg-3350 usage levels up tonot for fragrance use.
Recommendation for peg-3350 flavor usage levels up tonot for flavor use.

Penta International Corporation

Chemistry innovation

At Penta, our products and services help businesses do business better.

View All Website (973) 740-2300 lisaa@pentamfg.com

Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, (3350 mol EO average molar ratio) polyethylene glycol (3350) polyoxyethylene (3350) PubMed: A multiplexed microfluidic toolbox for the rapid optimization of affinity-driven partition in aqueous two phase systems. PubMed: Methylation, crystallization and SAD phasing of the Csu pilus CsuC-CsuE chaperone-adhesin subunit pre-assembly complex from Acinetobacter baumannii. PubMed: Crystallization and X-ray diffraction analysis of SpaE, a basal pilus protein from the gut-adapted Lactobacillus rhamnosus GG. PubMed: Purification and characterization of a collagenase from Penicillium sp. UCP 1286 by polyethylene glycol-phosphate aqueous two-phase system. PubMed: Structural analysis of binding functionality of folic acid-PEG dendrimers against folate receptor. PubMed: Binding studies and structure determination of the recombinantly produced type-II 3-dehydroquinate dehydratase from Acinetobacter baumannii. PubMed: Quality by design (QbD) approach for design and development of drug-device combination products: A case study on flunisolide nasal spray. PubMed: Anaphylaxis to Polyethylene Glycol (Colyte®) in a Patient with Diverticulitis. PubMed: Safety of polyethylene glycol 3350 solution in chronic constipation: randomized, placebo-controlled trial. PubMed: [Intestinal cleaning for colonoscopy in children: effectiveness, adherence and adverse effects of schemes differentiated by age]. PubMed: Putative thioredoxin Trx1 from Thermosipho africanus strain TCF52B: expression, purification and structural determination using S-SAD. PubMed: Polyethylene glycol 3350 in occasional constipation: A one-week, randomized, placebo-controlled, double-blind trial. PubMed: Optimal Solution Volume for Luminal Preservation: A Preclinical Study in Porcine Intestinal Preservation. PubMed: Aqueous two-phase system purification for superoxide dismutase induced by menadione from Phanerochaete chrysosporium. PubMed: Polyethylene glycol plus ascorbic acid is as effective as sodium picosulfate with magnesium citrate for bowel preparation: A randomized trial. PubMed: Cloning, expression, purification, crystallization and X-ray crystallographic analysis of recombinant human C1ORF123 protein. PubMed: Physicochemical characterization of spray-dried PLGA/PEG microspheres, and preliminary assessment of biological response. PubMed: An integrated practical implementation of continuous aqueous two-phase systems for the recovery of human IgG: From the microdevice to a multistage bench-scale mixer-settler device. PubMed: Investigation of the combined effect of MgO and PEG on the release profile of mefenamic acid prepared via hot-melt extrusion techniques. PubMed: Impact of microbial growth inhibition and proteolytic activity on the stability of a new formulation containing a phytate-degrading enzyme obtained from mushroom. PubMed: Enema versus polyethylene glycol for the management of rectal faecal impaction in children with constipation - a systematic review of randomised controlled trials. PubMed: Safety of a 1-Day Polyethylene Glycol 3350 Bowel Preparation for Colonoscopy in Children. PubMed: Kinetic and Structural Aspects of the Permeabilization of Biological and Model Membranes by Lichenysin. PubMed: Prucalopride: A Review in Chronic Idiopathic Constipation. PubMed: Expression, Crystallization and Preliminary X-ray Diffraction Analyses of Med-ORF10 in the Biosynthetic Pathway of an Antitumor Antibiotic Medermycin. PubMed: Crystallization and X-ray diffraction analysis of the HMG domain of the chondrogenesis master regulator Sox9 in complex with a ChIP-Seq-identified DNA element. PubMed: Crystallization and preliminary X-ray diffraction studies of frutalin, an α-D-galactose-specific lectin from Artocarpus incisa seeds. PubMed: Development of a three component complex to increase isoniazid efficacy against isoniazid resistant and nonresistant Mycobacterium tuberculosis. PubMed: Crystallization and X-ray diffraction analysis of a putative bacterial class I labdane-related diterpene synthase. PubMed: Crystallographic analysis of the N-terminal domain of Middle East respiratory syndrome coronavirus nucleocapsid protein. PubMed: Comparison of Polyethylene Glycol-Electrolyte Solution vs Polyethylene Glycol-3350 for the Treatment of Fecal Impaction in Pediatric Patients. PubMed: Crystallization and preliminary X-ray diffraction analysis of the Csu pili CsuC-CsuA/B chaperone-major subunit pre-assembly complex from Acinetobacter baumannii. PubMed: How Do US Gastroenterologists Use Over-the-Counter and Prescription Medications in Patients With Gastroesophageal Reflux and Chronic Constipation? PubMed: Randomised clinical study: Aspergillus niger-derived enzyme digests gluten in the stomach of healthy volunteers. PubMed: Expression, purification and preliminary crystallographic studies of human glutamate oxaloacetate transaminase 1 (GOT1). PubMed: [Estimation of atherogenic immune complexes containing modified lipoproteins in complement fixation tests]. PubMed: Expression, purification, crystallization and preliminary crystallographic analysis of a GH20 β-N-acetylglucosaminidase from the marine bacterium Vibrio harveyi. PubMed: Crystallization and preliminary crystallographic analysis of acetophenone reductase from Geotrichum candidum NBRC 4597. PubMed: Expression, purification, crystallization and preliminary X-ray diffraction analysis of the effector-interaction domain of the resistance protein RGA5-A from Oryza sativa L. japonica. PubMed: Cloning, expression, refolding, purification and preliminary crystallographic analysis of the sensory domain of the Campylobacter chemoreceptor for aspartate A (CcaA). PubMed: Purification, crystallization and preliminary X-ray crystallographic studies of Rv3899c from Mycobacterium tuberculosis. PubMed: Protein purification, crystallization and preliminary X-ray diffraction analysis of L-arabinose isomerase from Lactobacillus fermentum CGMCC2921. PubMed: Urticaria due to polyethylene glycol-3350 and electrolytes for oral solution in a patient with jejunal nodular lymphoid hyperplasia. PubMed: Structural measurements and cell line studies of the copper-PEG-Rifampicin complex against Mycobacterium tuberculosis. PubMed: Luminal solutions protect mucosal barrier during extended preservation. PubMed: Use of a novel microtitration protocol to obtain diffraction-quality crystals of 4-hydroxy-2-oxoglutarate aldolase from Bos taurus. PubMed: Crystallization and preliminary X-ray diffraction data of β-galactosidase from Aspergillus niger. PubMed: Purification, crystallization, preliminary X-ray diffraction and molecular-replacement studies of great cormorant (Phalacrocorax carbo) haemoglobin. PubMed: A study on the impact of hydroxypropyl methylcellulose on the viscosity of PEG melt suspensions using surface plots and principal component analysis. PubMed: Crystallization and preliminary X-ray diffraction analyses of the redox-controlled complex of terminal oxygenase and ferredoxin components in the Rieske nonhaem iron oxygenase carbazole 1,9a-dioxygenase. PubMed: Potential application of aqueous two-phase systems and three-phase partitioning for the recovery of superoxide dismutase from a clarified homogenate of Kluyveromyces marxianus. PubMed: Purification, crystallization and preliminary X-ray crystallographic studies of Rv3705c from Mycobacterium tuberculosis. PubMed: Bowel preparations for colonoscopy: an RCT. PubMed: Characterization, crystallization and preliminary X-ray crystallographic analysis of the Uba5 fragment necessary for high-efficiency activation of Ufm1. PubMed: Crystallization and preliminary X-ray diffraction analyses of the TIR domains of three TIR-NB-LRR proteins that are involved in disease resistance in Arabidopsis thaliana. PubMed: Crystallization and preliminary X-ray study of alanine dehydrogenase from Bacillus pseudofirmus OF4. PubMed: Crystallization and preliminary X-ray diffraction analysis of the flax cytokinin oxidase LuCKX1.1. PubMed: Novel extracellular PHB depolymerase from Streptomyces ascomycinicus: PHB copolymers degradation in acidic conditions. PubMed: Expression, purification, crystallization and preliminary crystallographic study of FtsA from methicillin-resistant Staphylococcus aureus. PubMed: Randomized clinical trial: macrogol/PEG 3350 plus electrolytes for treatment of patients with constipation associated with irritable bowel syndrome. PubMed: Heterogeneous nucleation helps the search for initial crystallization conditions of γ-glutamyl transpeptidase from Bacillus licheniformis. PubMed: Cloning, expression, crystallization and preliminary structural studies of dihydrodipicolinate reductase from Acinetobacter baumannii. PubMed: Crystallization and preliminary X-ray crystallographic analysis of the rhesus macaque MHC class I molecule Mamu-B*17 complexed with an immunodominant SIVmac239 Env epitope. PubMed: Polyethylene glycol 3350 based colon cleaning protocol: 2 d vs 4 d head to head comparison. PubMed: Split-dose administration of a dual-action, low-volume bowel cleanser for colonoscopy: the SEE CLEAR I study. PubMed: Randomised clinical trial: macrogol/PEG 3350+electrolytes versus prucalopride in the treatment of chronic constipation -- a comparison in a controlled environment. PubMed: A dual-action, low-volume bowel cleanser administered the day before colonoscopy: results from the SEE CLEAR II study. PubMed: Crystallization and preliminary X-ray diffraction analysis of mevalonate kinase from Methanosarcina mazei. PubMed: A critical evaluation and a search for the ideal colonoscopic preparation. PubMed: Tolerability, safety, and efficacy of PEG 3350 as a 1-day bowel preparation in children. PubMed: Expression, purification, crystallization and X-ray analysis of 3-quinuclidinone reductase from Agrobacterium tumefaciens. PubMed: Crystallization and preliminary crystallographic analysis of the NheA component of the Nhe toxin from Bacillus cereus. PubMed: Polyethylene glycol versus dual sugar assay for gastrointestinal permeability analysis: is it time to choose? PubMed: Structure of the branched-chain aminotransferase from Streptococcus mutans. PubMed: Prospective evaluation of 1-day polyethylene glycol-3350 bowel preparation regimen in children. PubMed: Expression, purification, crystallization and preliminary crystallographic studies of Rhagium inquisitor antifreeze protein. PubMed: OTC polyethylene glycol 3350 and pharmacists' role in managing constipation. PubMed: Intraluminal polyethylene glycol stabilizes tight junctions and improves intestinal preservation in the rat. PubMed: Crystal optimization and preliminary diffraction data analysis of the SCAN domain of Zfp206. PubMed: Cloning, purification, crystallization and preliminary X-ray analysis of the Burkholderia pseudomallei L1 ribosomal protein. PubMed: Crystallization and preliminary crystallographic analysis of Arabidopsis thaliana BRI1-associated kinase 1 (BAK1) cytoplasmic domain. PubMed: A bioprocess for the production of phytase from Schizophyllum commune: studies of its optimization, profile of fermentation parameters, characterization and stability. PubMed: Crystallization and preliminary X-ray analysis of S-ribosylhomocysteinase from Streptococcus mutans. PubMed: A randomized trial of enema versus polyethylene glycol 3350 for fecal disimpaction in children presenting to an emergency department. PubMed: Improving the diffraction of apoA-IV crystals through extreme dehydration. PubMed: Overproduction, purification, crystallization and preliminary X-ray diffraction analysis of Cockayne syndrome protein A in complex with DNA damage-binding protein 1. PubMed: Effect of PEG and mPEG-anthracene on tRNA aggregation and particle formation. PubMed: Expression, purification, crystallization and preliminary X-ray diffraction studies of the human keratin 4-binding domain of serine-rich repeat protein 1 from Streptococcus agalactiae. PubMed: Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from the grapevine Vitis vinifera. PubMed: Expression, purification and crystallization of an atypical class C acid phosphatase from Mycoplasma bovis. PubMed: Expression, purification, crystallization and preliminary X-ray analysis of eCGP123, an extremely stable monomeric green fluorescent protein with reversible photoswitching properties. PubMed: Purification and crystallization of Bacillus subtilis NrnA, a novel enzyme involved in nanoRNA degradation. PubMed: Folate receptor-targeted fluorescent paramagnetic bimodal liposomes for tumor imaging. PubMed: Higher molecular weight polyethylene glycol increases cell proliferation while improving barrier function in an in vitro colon cancer model. PubMed: Structure of fructose bisphosphate aldolase from Encephalitozoon cuniculi. PubMed: Conservation of a crystallographic interface suggests a role for β-sheet augmentation in influenza virus NS1 multifunctionality. PubMed: Crystallization and preliminary X-ray analysis of a putative sensor histidine kinase domain: the C-terminal domain of HksP4 from Aquifex aeolicus VF5. PubMed: PEG and mPEG-anthracene induce DNA condensation and particle formation. PubMed: Avoidance of PEG 3350 in patients with CHF, cirrhosis, and chronic kidney disease. PubMed: Two-day bowel preparation with polyethylene glycol 3350 and bisacodyl: a new, safe, and effective regimen for colonoscopy in children. PubMed: Distraction induced enterogenesis: a unique mouse model using polyethylene glycol. PubMed: Cloning, overexpression, purification, crystallization and preliminary X-ray diffraction analysis of an inositol monophosphatase family protein (SAS2203) from Staphylococcus aureus MSSA476. PubMed: Long-term follow-up of patients after antegrade continence enema procedure. PubMed: Expression, crystallization and preliminary X-ray analysis of the phosphoribosylglycinamide formyltransferase from Streptococcus mutans. PubMed: Crystallization and preliminary X-ray diffraction analysis of L,L-diaminopimelate aminotransferase (DapL) from Chlamydomonas reinhardtii. PubMed: Clinical efficacy and safety of polyethylene glycol 3350 versus liquid paraffin in the treatment of pediatric functional constipation. PubMed: Preparation and crystallization of the Grb7 SH2 domain in complex with the G7-18NATE nonphosphorylated cyclic inhibitor peptide. PubMed: MiraLAX is not as effective as GoLytely in bowel cleansing before screening colonoscopies. PubMed: Efficacy of bolus lukewarm saline and yoga postures as colonoscopy preparation: a pilot study. PubMed: Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from the psychrophile Shewanella benthica. PubMed: Purification, crystallization and preliminary X-ray analysis of the dissimilatory sulfite reductase from Desulfovibrio vulgaris Miyazaki F. PubMed: Crystallization and preliminary X-ray diffraction analysis of rat autotaxin. PubMed: Evidence-based recommendations for bowel cleansing before colonoscopy in children: a report from a national working group. PubMed: Protein preparation, crystallization and preliminary X-ray analysis of Trypanosoma cruzi nucleoside diphosphate kinase 1. PubMed: Crystallization and preliminary crystallographic analysis of the catalytic module of endolysin from Cp-7, a phage infecting Streptococcus pneumoniae. PubMed: Crystallization and preliminary crystallographic analysis of nosiheptide-resistance methyltransferase from Streptomyces actuosus in complex with SAM. PubMed: The Relationship between Small-Intestinal Bacterial Overgrowth and Intestinal Permeability in Patients with Irritable Bowel Syndrome. PubMed: Crystallization of the pneumococcal autolysin LytC: in-house phasing using novel lanthanide complexes. PubMed: Purification, crystallization and preliminary crystallographic analysis of very-long-chain acyl-CoA dehydrogenase from Caenorhabditis elegans. PubMed: One-day bowel preparation with polyethylene glycol 3350: an effective regimen for colonoscopy in children. PubMed: Use of the chloride channel activator lubiprostone for constipation in adults with cystic fibrosis: a case series. PubMed: Formulation and evaluation of pharmaceutically equivalent parenteral depot suspension of methyl prednisolone acetate. PubMed: Evaluation and modeling of the eutectic composition of various drug-polyethylene glycol solid dispersions. PubMed: Expression, purification, crystallization and preliminary X-ray analysis of maleylacetate reductase from Burkholderia sp. strain SJ98. PubMed: Crystallization and preliminary X-ray analysis of a monomeric mutant of Azami-Green (mAG), an Aequorea victoria green fluorescent protein-like green-emitting fluorescent protein from the stony coral Galaxea fascicularis. PubMed: Purification, crystallization and preliminary X-ray diffraction analysis of disease-related mutants of p97. PubMed: Expression, purification, crystallization and preliminary X-ray analysis of conjugated polyketone reductase C2 (CPR-C2) from Candida parapsilosis IFO 0708. PubMed: Crystal optimization and preliminary diffraction data analysis of the Smad1 MH1 domain bound to a palindromic SBE DNA element. PubMed: Purification, crystallization and preliminary X-ray diffraction studies of parakeet (Psittacula krameri) haemoglobin. PubMed: Crystallization and preliminary X-ray analysis of ZHE1, a hatching enzyme from the zebrafish Danio rerio. PubMed: Effect of molecular weight, temperature, and additives on the moisture sorption properties of polyethylene glycol. PubMed: Crystallization and preliminary X-ray analysis of gamma-hexachlorocyclohexane dehydrochlorinase LinA from Sphingobium japonicum UT26. PubMed: Purification, crystallization and preliminary crystallographic study of haemoglobin from camel (Camelus dromedarius): a high oxygen-affinity lowland species. PubMed: A randomized, double-blind, placebo-controlled trial of polyethylene glycol effects on fasting and postprandial rectal sensitivity and symptoms in hypersensitive constipation-predominant irritable bowel syndrome. PubMed: Purification, crystallization and preliminary X-ray analysis of haemoglobin from ostrich (Struthio camelus). PubMed: Purification and preliminary X-ray crystallographic studies of beta-microseminoprotein from human seminal plasma. PubMed: Purification, crystallization and preliminary X-ray diffraction studies on goat (Capra hircus) hemoglobin - a low oxygen affinity species. PubMed: Crystallization and preliminary X-ray analysis of D-2-hydroxyacid dehydrogenase from Haloferax mediterranei. PubMed: Crystallization and preliminary crystallographic analysis of a chitinase from Clonostachys rosea. PubMed: Influence of additives on melt viscosity, surface tension, and film formation of dry powder coatings. PubMed: Application of aqueous two-phase systems to antibody purification: a multi-stage approach. PubMed: Downstream processing of antibodies: single-stage versus multi-stage aqueous two-phase extraction. PubMed: Purification, crystallization and preliminary crystallographic study of low oxygen-affinity haemoglobin from cat (Felis silvestris catus) in two different crystal forms. PubMed: Expression, purification and preliminary X-ray diffraction studies of VERNALIZATION1(208-341) from Arabidopsis thaliana. PubMed: Preliminary Crystallographic Study of Hemoglobin from Buffalo (Bubalus bubalis): A Low Oxygen Affinity Species. PubMed: Expression, purification, crystallization and preliminary X-ray diffraction analysis of dihydrodipicolinate synthase from Bacillus anthracis in the presence of pyruvate. PubMed: Crystallization and preliminary X-ray analysis of 2,3-diketo-5-methylthiopentyl-1-phosphate enolase from Bacillus subtilis. PubMed: Purification, crystallization and preliminary X-ray diffraction studies on avian haemoglobin from pigeon (Columba livia). PubMed: Crystallization and preliminary X-ray analysis of a C-terminal fragment of FlgJ, a putative flagellar rod cap protein from Salmonella. PubMed: Purification, crystallization and preliminary X-ray diffraction analysis of the HMG domain of Sox17 in complex with DNA. PubMed: Cloning, expression, purification, crystallization and preliminary X-ray analysis of NodS N-methyltransferase from Bradyrhizobium japonicum WM9. PubMed: Purification, crystallization and preliminary X-ray diffraction analysis of human Gadd45gamma. PubMed: Expression, purification and crystallization of the ecto-enzymatic domain of rat E-NTPDase1 CD39. PubMed: Crystallization and preliminary X-ray analysis of isomaltase from Saccharomyces cerevisiae. PubMed: Crystallization and preliminary characterization of dihydropteridine reductase from Dictyostelium discoideum. PubMed: Integrated process for the purification of antibodies combining aqueous two-phase extraction, hydrophobic interaction chromatography and size-exclusion chromatography. PubMed: Stool consistency and stool frequency are excellent clinical markers for adequate colon preparation after polyethylene glycol 3350 cleansing protocol: a prospective clinical study in children. PubMed: Three crystal forms of the bifunctional enzyme proline utilization A (PutA) from Bradyrhizobium japonicum. PubMed: Influence of polymeric subcoats on the drug release properties of tablets powder-coated with pre-plasticized Eudragit L 100-55. PubMed: Feasibility of polyethylene glycol (PEG) 3350 (Miralax) for colon preparation prior to lower endoscopic examination in healthy adults; experience in a community clinic setting. PubMed: Polyethylene glycol-mediated colorectal cancer chemoprevention: roles of epidermal growth factor receptor and Snail. PubMed: Development of clinical dosage forms for a poorly water-soluble drug II: formulation and characterization of a novel solid microemulsion preconcentrate system for oral delivery of a poorly water-soluble drug. PubMed: Crystallization and preliminary crystallographic analysis of Gibberella zeae extracellular lipase. PubMed: Crystallization and preliminary crystallographic analysis of tRNA (m(7)G46) methyltransferase from Escherichia coli. PubMed: Purification, crystallization and preliminary crystallographic analysis of DehI, a group I alpha-haloacid dehalogenase from Pseudomonas putida strain PP3. PubMed: Use of Powder PEG-3350 as a Sole Bowel Preparation: Clinical Case Series of 245 Patients. PubMed: Citric acid monohydrate as a release-modifying agent in melt extruded matrix tablets. PubMed: Crystallization and preliminary X-ray analysis of vicenisaminyltransferase VinC. PubMed: Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of the central zinc-binding domain of the human Mcm10 DNA-replication factor. PubMed: PEG3350 in the treatment of childhood constipation: a multicenter, double-blinded, placebo-controlled trial. PubMed: Clinical trial: single- and multiple-dose pharmacokinetics of polyethylene glycol (PEG-3350) in healthy young and elderly subjects. PubMed: Crystallization and preliminary X-ray characterization of the catalytic domain of collagenase G from Clostridium histolyticum. PubMed: Crystallization of a flavodoxin involved in nitrogen fixation in Rhodobacter capsulatus. PubMed: Preparation, crystallization and preliminary X-ray diffraction analysis of the DNA-binding domain of the Ets transcription factor in complex with target DNA. PubMed: Interactive mixture as a rapid drug delivery system. PubMed: Crystallization and preliminary crystallographic analysis of human Ca 2+-loaded calbindin-D28k. PubMed: Differences in taste between two polyethylene glycol preparations. PubMed: A comparison of polyethylene glycol laxative and placebo for relief of constipation from constipating medications. PubMed: Crystallization of sheep (Ovis aries) and goat (Capra hircus) haemoglobins under unbuffered low-salt conditions. PubMed: Comparison of the removal of 2,4-dichlorophenol and phenol from polluted water, by peroxidases from tomato hairy roots, and protective effect of polyethylene glycol. PubMed: Purification, crystallization and preliminary X-ray analysis of a Nup107-Nup133 heterodimeric nucleoporin complex. PubMed: Binding assay and preliminary X-ray crystallographic analysis of ACTIBIND, a protein with anticarcinogenic and antiangiogenic activities. PubMed: SAD phasing of a structure based on cocrystallized iodides using an in-house Cu Kalpha X-ray source: effects of data redundancy and completeness on structure solution. PubMed: Preparation of plasmid DNA polyplexes from alkaline lysates by a two-step aqueous two-phase extraction process. PubMed: A randomized, multicenter comparison of polyethylene glycol laxative and tegaserod in treatment of patients with chronic constipation. PubMed: Affinity partitioning of human antibodies in aqueous two-phase systems. PubMed: Crystallization and preliminary X-ray analysis of PH1010 from Pyrococcus horikoshii OT3, a member of the archaeal DUF54 family of proteins. PubMed: A Randomised, Controlled Comparison of Low-Dose Polyethylene Glycol 3350 plus Electrolytes with Ispaghula Husk in the Treatment of Adults with Chronic Functional Constipation. PubMed: Influence of processing parameters and formulation factors on the drug release from tablets powder-coated with Eudragit L 100-55. PubMed: A randomized, multicenter, placebo-controlled trial of polyethylene glycol laxative for chronic treatment of chronic constipation. PubMed: One-step purification of histone deacetylase from Escherichia coli cell-lysate by counter-current chromatography using aqueous two-phase system. PubMed: A method for three-dimensional protein characterization and its application to a complex plant (corn) extract. PubMed: Application of central composite design to the optimisation of aqueous two-phase extraction of human antibodies. PubMed: Searching for silver bullets: an alternative strategy for crystallizing macromolecules. PubMed: Crystallization and preliminary X-ray diffraction analysis of two N-terminal fragments of the DNA-cleavage domain of topoisomerase IV from Staphylococcus aureus. PubMed: Crystallization and preliminary X-ray analysis of human S100A13. PubMed: A Novel PEG 3350 Formulation. PubMed: Effect of the melt granulation technique on the dissolution characteristics of griseofulvin. PubMed: Crystallization and preliminary crystallographic study of carnosinase CN2 from mice. PubMed: The purification, crystallization and preliminary structural characterization of PhzM, a phenazine-modifying methyltransferase from Pseudomonas aeruginosa. PubMed: Chemoprevention of colon carcinogenesis by polyethylene glycol: suppression of epithelial proliferation via modulation of SNAIL/beta-catenin signaling. PubMed: Aqueous-aqueous two-phase systems composed of low molecular weight of polyethylene glycols and dextrans for counter-current chromatographic purification of proteins. PubMed: Purification, crystallization and preliminary crystallographic study of an IDS-epimerase from Agrobacterium tumefaciens BY6. PubMed: Overexpression, purification and crystallization of a choline-binding protein CbpI from Streptococcus pneumoniae. PubMed: Purification and crystallization of the catalytic PRONE domain of RopGEF8 and its complex with Rop4 from Arabidopsis thaliana. PubMed: The purification, crystallization and preliminary structural characterization of human MAWDBP, a member of the phenazine biosynthesis-like protein family. PubMed: Rotavirus-like particles primary recovery from insect cells in aqueous two-phase systems. PubMed: Investigation of RNA structure in satellite panicum mosaic virus. PubMed: Expression, purification and crystallization of Streptococcus dysgalactiae-derived mitogen. PubMed: Purification, partial characterization and preliminary X-ray diffraction analysis of a mannose-specific lectin from Cymbosema roseum seeds. PubMed: Crystallization of a newly discovered histidine acid phosphatase from Francisella tularensis. PubMed: Crystallization and diffraction properties of the Fab fragment of 3B5H10, an antibody specific for disease-causing polyglutamine stretches. PubMed: Crystallization and preliminary crystallographic analysis of the human calcineurin homologous protein CHP2 bound to the cytoplasmic region of the Na+/H+ exchanger NHE1. PubMed: Crystallization and preliminary X-ray analysis of a truncated mutant of yeast nuclear thiol peroxidase, a novel atypical 2-Cys peroxiredoxin. PubMed: Crystallization and preliminary X-ray diffraction analysis of the electron-transfer complex between the terminal oxygenase component and ferredoxin in the Rieske non-haem iron oxygenase system carbazole 1,9a-dioxygenase. PubMed: Purification, crystallization and preliminary X-ray analysis of Enterococcus faecium aminoglycoside-2''-phosphotransferase-Ib [APH(2'')-Ib]. PubMed: Crystallization and preliminary crystallographic analysis of L-asparaginase from Erwinia carotovora. PubMed: Crystallization and preliminary crystallographic data of a Fel d 1 (1+2) construct corresponding to the major allergen from cat. PubMed: Structure of Mesorhizobium loti arylamine N-acetyltransferase 1. PubMed: Urinary excretion of polyethylene glycol 3350 during colonoscopy preparation. PubMed: Systematic Review: FDA-Approved Prescription Medications for Adults With Constipation. PubMed: Lack of lasting effectiveness of PEG 3350 laxative treatment of constipation. PubMed: Contemporary and emerging drug treatments for urinary incontinence in children. PubMed: Structure of human thymidylate synthase under low-salt conditions. PubMed: Crystallization and preliminary X-ray characterization of the atypical glutaminyl-tRNA synthetase from Deinococcus radiodurans. PubMed: Soft perforation of planar bilayer lipid membranes of dipalmitoylphosphatidylcholine at the temperature of the phase transition from the liquid crystalline to the gel state. PubMed: PEG 3350 (Transipeg) versus lactulose in the treatment of childhood functional constipation: a double blind, randomised, controlled, multicentre trial. PubMed: [The effect of polyethylene glycol in chronic constipation is not sufficiently evaluated. A systematic literature review]. PubMed: Expression, crystallization and phasing of vacuolar H(+)-ATPase subunit C (Vma5p) of Saccharomyces cerevisiae. PubMed: Polyethylene glycol inhibits intestinal neoplasia and induces epithelial apoptosis in Apc(min) mice. PubMed: The production and purification of the human T-cell receptors, the CD3epsilongamma and CD3epsilondelta heterodimers: complex formation and crystallization with OKT3, a therapeutic monoclonal antibody. PubMed: Polyethylene glycol for constipation in children younger than eighteen months old. PubMed: Development of mucoadhesive dosage forms of buprenorphine for sublingual drug delivery. PubMed: Purification and crystallization of the heterodimeric complex of RARbeta and RXRalpha ligand-binding domains in the active conformation. PubMed: Calcium phosphate-PEG-insulin-casein (CAPIC) particles as oral delivery systems for insulin. PubMed: Detection of L-lactate in polyethylene glycol solutions confirms the identity of the active-site ligand in a proline dehydrogenase structure. PubMed: Crystallization and preliminary crystallographic analysis of a native chitinase from the fungal pathogen Aspergillus fumigatus YJ-407. PubMed: Expression, purification, crystallization and preliminary X-ray crystallographic studies of Mycobacterium tuberculosis thioredoxin reductase. PubMed: Purification, crystallization and preliminary structural characterization of human Rap1GAP. PubMed: Polyethylene glycol 3350 without electrolytes: a new safe, effective, and palatable bowel preparation for colonoscopy in children. PubMed: Cloning, expression, purification, crystallization and preliminary X-ray analysis of human liver glyceraldehyde-3-phosphate dehydrogenase. PubMed: Pediatric constipation therapy using guidelines and polyethylene glycol 3350. PubMed: [Colonic lavage prior to colonoscopy: comparable outcomes of two polyethylene-glycol preparations and a sodium-phosphate solution]. PubMed: Bioavailability enhancement of a poorly water-soluble drug by solid dispersion in polyethylene glycol-polysorbate 80 mixture. PubMed: Highly effective poly(ethylene glycol) architectures for specific inhibition of immune receptor activation. PubMed: Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of the structural domain of the nucleocapsid N protein from porcine reproductive and respiratory syndrome virus (PRRSV). PubMed: Crystallization and preliminary X-ray analysis of an anti-LewisX Fab fragment with and without its LewisX antigen. PubMed: Crystallization and initial X-ray diffraction of BtuB, the integral membrane cobalamin transporter of Escherichia coli. PubMed: Crystallization and preliminary X-ray analysis of the ytxM gene product from Bacillus subtilis. PubMed: Purification and crystallization of coconut globulin cocosin from Cocos nucifera. PubMed: Dose response of PEG 3350 for the treatment of childhood fecal impaction. PubMed: Overnight efficacy of polyethylene glycol laxative. PubMed: Comparison of polyethylene glycol 3350 and lactulose for treatment of chronic constipation in children. PubMed: Economic impact of low dose polyethylene glycol 3350 plus electrolytes compared with lactulose in the management of idiopathic constipation in the UK. PubMed: Targeted PEG-based bioconjugates enhance the cellular uptake and transport of a HIV-1 TAT nonapeptide. PubMed: Comparison of the gravimetric, phenol red, and 14C-PEG-3350 methods to determine water absorption in the rat single-pass intestinal perfusion model. PubMed: Efficacy and optimal dose of daily polyethylene glycol 3350 for treatment of constipation and encopresis in children. PubMed: Gut luminal endotoxin reduces ischemia-reperfusion injury of the small gut in germ-free pigs. PubMed: Scale-up of recombinant cutinase recovery by whole broth extraction with PEG-phosphate aqueous two-phase. PubMed: Crystallization and preliminary X-ray diffraction studies of the epsilonzeta addiction system encoded by Streptococcus pyogenes plasmid pSM19035. PubMed: Bioadhesive properties of hydroxypropylcellulose topical films produced by hot-melt extrusion. PubMed: Identification of many crystal forms of Aspergillus nidulans dehydroquinate synthase. PubMed: Diffusion of n-butyl-p-aminobenzoate (BAB), lidocaine and bupivacaine through the human dura-arachnoid mater in vitro. PubMed: Drowning-out crystallisation of sodium sulphate using aqueous two-phase systems. PubMed: Physical-mechanical, moisture absorption and bioadhesive properties of hydroxypropylcellulose hot-melt extruded films. PubMed: X-ray studies of recombinant anti-testosterone Fab fragments: the use of PEG 3350 in crystallization. PubMed: Partial purification of penicillin acylase from Escherichia coli in poly(ethylene glycol)-sodium citrate aqueous two-phase systems. PubMed: Early increase in intestinal permeability in patients with severe acute pancreatitis: correlation with endotoxemia, organ failure, and mortality. PubMed: Crystallization of the immunodominant outer membrane protein OmpC; the first protein crystals from Salmonella typhi, a human pathogen. PubMed: Comparison of a low dose polyethylene glycol electrolyte solution with lactulose for treatment of chronic constipation. PubMed: Variation of penicillin acylase partition coefficient with phase volume ratio in poly(ethylene glycol)-sodium citrate aqueous two-phase systems. PubMed: Aqueous two-phase partition and detergent precipitation of a drug-responsive NADH oxidase from the HeLa cell surface. PubMed: Expression, purification, and crystallization of the DNA-binding domain from the Saccharomyces cerevisae cell-cycle transcription factor MBP-1. PubMed: Validation of polyethylene glycol 3350 as a poorly absorbable marker for intestinal perfusion studies. PubMed: Crystallization of rat procathepsin B. PubMed: Crystallization and preliminary X-ray studies of ornithine decarboxylase from Trypanosoma brucei. PubMed: Crystallization of intact monoclonal antibodies. PubMed: An in-vitro evaluation of silicone elastomer latex for topical drug delivery. PubMed: Crystallization and preliminary X-ray diffraction studies of the cartilage link protein from bovine trachea. PubMed: Crystallization and preliminary X-ray diffraction studies of a bacterial flavohemoglobin protein. PubMed: Colyte and Colyte-flavored (PEG-3350 & electrolytes) for oral solution for gastrointestinal lavage. PubMed: Stabilizing effect of amphiphilic excipients on the freeze-thawing and freeze-drying of lactate dehydrogenase. PubMed: Additive effects of thermal injury and infection on gut permeability. PubMed: Gut macromolecular permeability in pancreatitis correlates with severity of disease in rats. PubMed: Structural properties of polyethylene glycol-polysorbate 80 mixture, a solid dispersion vehicle. PubMed: Polyethylene glycol enhanced protein refolding. PubMed: Separation and quantitation of polyethylene glycols 400 and 3350 from human urine by high-performance liquid chromatography. PubMed: NuLYTELY (PEG 3350, sodium chloride, sodium bicarbonate and potassium chloride for oral solution). PubMed: Preparation and crystallization of a human immunodeficiency virus p24-Fab complex. PubMed: Cosolvent assisted protein refolding. PubMed: Two-week aerosol inhalation study on polyethylene glycol (PEG) 3350 in F-344 rats. PubMed: Osmotic effects of polyethylene glycol.