poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, (600 mol EO average molar ratio)

CAS: 25322-68-3

Identification

Namepeg-600
CAS Number25322-68-3
FDA UNIISearch

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 1e+006 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral Toxicityintravenous-dog LDLo 3000 mg/kg
Dermal Toxicitysubcutaneous-mouse LD50 18000 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'KIDNEY, URETER, AND BLADDER: HEMATURIA\nVASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION\nCARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION)']

Safety in Use

Categoryinformation only not used for fragrances or flavors
Recommendation for peg-600 usage levels up tonot for fragrance use.
Recommendation for peg-600 flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, (600 mol EO average molar ratio) polyethylene glycol (600) polyoxyethylene (600) PubMed: Development and Application of an MS(ALL)-Based Approach for the Quantitative Analysis of Linear Polyethylene Glycols in Rat Plasma by Liquid Chromatography Triple-Quadrupole/Time-of-Flight Mass Spectrometry. PubMed: Recovery of lignin peroxidase from submerged liquid fermentation of Amauroderma rugosum (Blume & T. Nees) Torrend using polyethylene glycol/salt aqueous two-phase system. PubMed: Asymmetric Catalytic 1,2-Hydroperoxidation of Isatin-Derived Ketimine with Hydrogen Peroxide in the Crowding Environment of PEGs. PubMed: Structure and Conformational Properties of d-Glucose/d-Galactose-Binding Protein in Crowded Milieu. PubMed: In vivo evaluation of a self-nanoemulsifying drug delivery system for curcumin. PubMed: Alendronate-anchored PEGylation of ceria nanoparticles promotes human hepatoma cell proliferation via AKT/ERK signaling pathways. PubMed: Peculiarities of the Super-Folder GFP Folding in a Crowded Milieu. PubMed: Eco-friendly PEG-based controlled release nano-formulations of Mancozeb: Synthesis and bioefficacy evaluation against phytopathogenic fungi Alternaria solani and Sclerotium rolfsii. PubMed: Generation of gas-phase ions from charged clusters: an important ionization step causing suppression of matrix and analyte ions in matrix-assisted laser desorption/ionization mass spectrometry. PubMed: Formulation, characterization, in vitro and in vivo evaluation of castor oil based self-nano emulsifying levosulpiride delivery systems. PubMed: Enhanced oral delivery of risperidone through a novel self-nanoemulsifying powder (SNEP) formulations: in-vitro and ex-vivo assessment. PubMed: Liquid PEG Polymers Containing Antioxidants: A Versatile Platform for Studying Oxygen-Sensitive Photochemical Processes. PubMed: Mechanisms of imiquimod skin penetration. PubMed: Development and evaluation of viscosity-enhanced nanocarrier (VEN) for oral insulin delivery. PubMed: Structure and stability of recombinant bovine odorant-binding protein: III. Peculiarities of the wild type bOBP unfolding in crowded milieu. PubMed: Effect of coating thickness of iron oxide nanoparticles on their relaxivity in the MRI. PubMed: Experimental Strategies to Bridge Large Tissue Gaps in the Injured Spinal Cord after Acute and Chronic Lesion. PubMed: Interrelationship between partition behavior of organic compounds and proteins in aqueous dextran-polyethylene glycol and polyethylene glycol-sodium sulfate two-phase systems. PubMed: Thyroid hormone (levothyroxine) replacement via the respiratory route by inhalation: in vitro exploratory studies. PubMed: Crack-free polydimethylsiloxane-bioactive glass-poly(ethylene glycol) hybrid monoliths with controlled biomineralization activity and mechanical property for bone tissue regeneration. PubMed: Lipid-polyethylene glycol based nano-ocular formulation of ketoconazole. PubMed: Microwave assisted efficient synthesis of diphenyl substituted pyrazoles using PEG-600 as solvent - A green approach. PubMed: Polyethylene glycol and divalent salt-induced DNA reentrant condensation revealed by single molecule measurements. PubMed: Positional impact of fluorescently modified G-tetrads within polymorphic human telomeric G-quadruplex structures. PubMed: Fabrication of triblock ABA type peptide dendrimer based on glutamic acid dimethyl ester and PEG as a potential nano drug delivery agent. PubMed: Cellulosic/wool pigment prints with remarkable antibacterial functionalities. PubMed: Purification, crystallization and preliminary X-ray analysis of a putative nucleotide phosphohydrolase, YpgQ, from Bacillus subtilis. PubMed: Formulation of fenofibrate liquisolid tablets using central composite design. PubMed: Devitrification and recrystallization of nanoparticle-containing glycerol and PEG-600 solutions. PubMed: Use of nonelectrolytes reveals the channel size and oligomeric constitution of the Borrelia burgdorferi P66 porin. PubMed: Characterization of a nonribosomal peptide antibiotic solid dispersion formulation by process analytical technologies sensors. PubMed: Development and characterization of dilutable self-microemulsifying premicroemulsion systems (SMEPMS) as templates for preparation of nanosized particulates. PubMed: Effect of salt additives on protein partition in polyethylene glycol-sodium sulfate aqueous two-phase systems. PubMed: Solvent-controlled halo-selective selenylation of aryl halides catalyzed by Cu(II) supported on Al2O3. A general protocol for the synthesis of unsymmetrical organo mono- and bis-selenides. PubMed: Synthetic evaluation of disulphide-bonded sarafotoxin on a poly(oxy ether) grafted dendrimeric poly(alkyl amine) support for polymer assisted organic synthesis. PubMed: Development of controlled release formulations of thiram employing amphiphilic polymers and their bioefficacy evaluation in seed quality enhancement studies. PubMed: Development and physico-mechanical characterization of carrageenan and poloxamer-based lyophilized matrix as a potential buccal drug delivery system. PubMed: Application of parylene for surface (polymer) enhanced laser desorption/ionization of synthetic polymers. PubMed: Study on Mixed Solvency Concept in Formulation Development of Aqueous Injection of Poorly Water Soluble Drug. PubMed: Non-ionic dendronized multiamphiphilic polymers as nanocarriers for biomedical applications. PubMed: Influence of hybrid inorganic/organic mesoporous and nanostructured materials on the cephalosporins' efficacy on different bacterial strains. PubMed: Development of lyophilization cycle and effect of excipients on the stability of catalase during lyophilization. PubMed: Influence of MRI contrast media on histamine release from mast cells. PubMed: Evaluation of water uptake and mechanical properties of blended polymer films for preparing gas-generated multiple-unit floating drug delivery systems. PubMed: Aqueous two-phase extraction for the purification of alkaline agarases from culture extracts of Pseudomonas aeruginosa AG LSL-11. PubMed: Poly(acrylic acid)/poly(ethylene glycol) adduct for attaining multifunctional cellulosic fabrics. PubMed: A high activity photocatalyst of hierarchical 3D flowerlike ZnO microspheres: synthesis, characterization and catalytic activity. PubMed: Enhanced cell uptake of superparamagnetic iron oxide nanoparticles through direct chemisorption of FITC-Tat-PEG₆₀₀-b-poly(glycerol monoacrylate). PubMed: Bioefficacy evaluation of controlled release formulations based on amphiphilic nano-polymer of carbofuran against Meloidogyne incognita infecting tomato. PubMed: Crosslinked chitosan nanoparticle formulations for delivery from pressurized metered dose inhalers. PubMed: Novel films for drug delivery via the buccal mucosa using model soluble and insoluble drugs. PubMed: Biofunctionalization of titanium with PEG and anti-CD34 for hemocompatibility and stimulated endothelialization. PubMed: Self-assembly of amphiphilic glycoconjugates into lectin-adhesive nanoparticles. PubMed: Biocatalytic route to sugar-PEG-based polymers for drug delivery applications. PubMed: Controllable synthesis and luminescent properties of three-dimensional nanostructured CaWO4:Tb3+ microspheres. PubMed: Facile synthesis of 3D flowerlike CeO2 microspheres under mild condition with high catalytic performance for CO oxidation. PubMed: A novel cold-adapted lipase from Acinetobacter sp. XMZ-26: gene cloning and characterisation. PubMed: Pore size prediction of polyethersulfone ultrafiltration membranes using artificial neural networks. PubMed: PEGylated N-methyl-S-methyl dithiocarbazate as a new reagent for the high-yield preparation of nitrido Tc-99m and Re-188 radiopharmaceuticals. PubMed: Doxycycline hydrogels with reversible disulfide crosslinks for dermal wound healing of mustard injuries. PubMed: Impact of osmotic/matric stress and heat shock on environmental tolerance induction of bacterial biocontrol agents against Fusarium verticillioides. PubMed: Studies on the conformational change of adsorbed BSA onto a moderately hydrophobic surface at different denaturant concentrations and surface coverages. PubMed: Dual affinity method for plasmid DNA purification in aqueous two-phase systems. PubMed: Rapid identification of stabilisers in polypropylene using time-of-flight mass spectrometry and DART as ion source. PubMed: Effect of polyethylene glycol on the thermal stability of green fluorescent protein. PubMed: Preparation of TiO(2)/Ag colloids with ultraviolet resistance and antibacterial property using short chain polyethylene glycol. PubMed: Nitric oxide, actin reorganization and vacuoles change are involved in PEG 6000-induced stomatal closure in Vicia faba. PubMed: Temperature-sensitive biodegradable poly(ethylene glycol). PubMed: [DSC and FTIR study of adsorbed lysozyme on hydrophobic surface]. PubMed: Liquid-liquid extraction of some lanthanide metal ions by polyoxyalkylene systems. PubMed: Mucoadhesive polymeric hydrogels for nasal delivery of acyclovir. PubMed: Affinity partitioning of plasmid DNA with a zinc finger protein. PubMed: Cholesterol binding to amyloid-beta fibrils: a TEM study. PubMed: Crystallization and preliminary X-ray characterization of queD from Bacillus subtilis, an enzyme involved in queuosine biosynthesis. PubMed: Preparation of plasmid DNA polyplexes from alkaline lysates by a two-step aqueous two-phase extraction process. PubMed: Aqueous two-phase recovery of bio-nanoparticles: a miniaturization study for the recovery of bacteriophage T4. PubMed: An approach for increasing the mass recovery of proteins derived from inclusion bodies in biotechnology. PubMed: Enhanced mixture analysis of poly(ethylene glycol) using high-field asymmetric waveform ion mobility spectrometry combined with fourier transform ion cyclotron resonance mass spectrometry. PubMed: Detection of lymphocystis disease virus (LCDV) in asymptomatic cultured gilt-head seabream (Sparus aurata, L.) using an immunoblot technique. PubMed: Towards an understanding of adsorption behaviour in non-aqueous systems: adsorption of poly(vinyl pyrrolidone) and poly(ethylene glycol) onto silica from 2H, 3H-perfluoropentane. PubMed: [Simultaneous purification of superoxide dismutase, catalase and hemoglobin from bovine erythrocyte lysate with PEG 600 as chaperon]. PubMed: Explaining the phase behaviour of the pharmaceutically relevant polymers poly(ethylene glycol) and poly(vinyl pyrrolidone) in semi-fluorinated liquids. PubMed: Purification of plasmid DNA vectors by aqueous two-phase extraction and hydrophobic interaction chromatography. PubMed: [Spectrophotometric assay of polyethyene glycol in urine using ammonium ferrothiocyanate aqueous-chloroform system]. PubMed: Physical characterizations of microemulsion systems using tocopheryl polyethylene glycol 1000 succinate (TPGS) as a surfactant for the oral delivery of protein drugs. PubMed: Polyethylene glycol-grafted bovine pericardium: a novel hybrid tissue resistant to calcification. PubMed: Synthesis and characterization of polyurethane and poly(ether urethane) nanocapsules using a new technique of interfacial polycondensation combined to spontaneous emulsification. PubMed: Formulation dependent pharmacokinetics, bioavailability and renal toxicity of a selective cyclooxygenase-1 inhibitor SC-560 in the rat. PubMed: Recovery of the proteose peptone component 3 from cheese whey in Reppal PES 100/polyethylene glycol aqueous two-phase systems. PubMed: Crystallization and preliminary X-ray diffraction studies of a novel alcohol dehydrogenase from the hyperthermophilic archaeon Aeropyrum pernix. PubMed: In vitro fibrillogenesis of the amyloid beta 1-42 peptide: cholesterol potentiation and aspirin inhibition. PubMed: Isolation of plasmid DNA from cell lysates by aqueous two-phase systems. PubMed: Biocompatibility evaluation of ePTFE membrane modified with PEG in atmospheric pressure glow discharge. PubMed: Involvement of osmotic cell shrinkage on the proton extrusion rate in Saccharomyces cerevisiae. PubMed: The effects of plasticizers and titanium dioxide on the properties of poly(vinyl alcohol) coatings. PubMed: Requirements for osmosensing and osmotic activation of transporter ProP from Escherichia coli. PubMed: The use of 1H-NMR spectroscopy and refractometry for investigation of the distribution of nonelectrolytes of N-alcohol series between human red blood cells and extracellular medium. PubMed: Evaluation of absorbability of poorly water-soluble drugs: validity of the use of additives. PubMed: Study of phase behavior of poly(ethylene glycol)-polysorbate 80 and poly(ethylene glycol)-polysorbate 80-water mixtures. PubMed: Site-specific insulin conjugates with enhanced stability and extended action profile. PubMed: Water and temperature relations of growth of the entomogenous fungi beauveria bassiana, metarhizium anisopliae, and paecilomyces farinosus PubMed: The effect of formulation parameters on the size of poly-((2-dimethylamino)ethyl methacrylate)-plasmid complexes. PubMed: [Capillary free zone electrophoresis of globin chains]. PubMed: Use of aqueous two-phase systems for in situ extraction of water soluble antibiotics during their synthesis by enzymes immobilized on porous supports. PubMed: Centrifugal partition chromatographic reaction for the production of chiral amino acids. PubMed: Enhanced diffractivity of phosphoglucomutase crystals. Use of an alternative cryocrystallographic procedure. PubMed: Permeability studies of cellulose acetate free films for transdermal use: influence of plasticizers. PubMed: Synthesis, structure-activity relationships, and the effect of polyethylene glycol on inhibitors of phosphatidylinositol-specific phospholipase C from Bacillus cereus. PubMed: Crystallization and preliminary diffraction studies of NodL, a rhizobial O-acetyl-transferase involved in the host-specific nodulation of legume roots. PubMed: Improved oral absorption of L-365,260, a poorly soluble drug. PubMed: Functional role of follicular cells in the generation of osmolarity-dependent Cl- currents in Xenopus follicles. PubMed: Crystallization and preliminary X-ray diffraction studies of complexes between an influenza hemagglutinin and Fab fragments of two different monoclonal antibodies. PubMed: Effect of polyol molecular weight on the physical properties and haemocompatibility of polyurethanes containing polyethylene oxide macroglycols. PubMed: Extraction of cephalosporin C from whole broth and separation of desacetyl cephalosporin C by aqueous two-phase partition. PubMed: Protection from reperfusion-induced arrhythmias by polyethylene glycol 600. PubMed: Crystallization of phosphatidylinositol-specific phospholipase C from Bacillus cereus. PubMed: Purification, crystallization and preliminary X-ray analysis of the 3-phosphoglycerate kinase from Bacillus stearothermophilus. PubMed: Microencapsulation of solid dispersions: release of griseofulvin from griseofulvin:phospholipid coprecipitates in microspheres. PubMed: Self-emulsifying drug delivery systems: formulation and biopharmaceutic evaluation of an investigational lipophilic compound. PubMed: [The use of monolaurates for removing endotoxins from preparations of cell-free pertussis vaccine]. PubMed: High-performance liquid chromatographic determination of PEG 600 in human urine. PubMed: [Fusion of protoplasts of inactive variants of 2 producers of actinomycin C and the biosynthesis of an antibiotic of non- actinomycin nature]. PubMed: Absorption of polyethylene glycols 600 through 2000: the molecular weight dependence of gastrointestinal and nasal absorption. PubMed: The molecular weight dependence of nasal absorption: the effect of absorption enhancers. PubMed: Rapid low molecular weight polyethylene glycol embedding protocol for immunocytochemistry. PubMed: The effect of cross-linking agents on the impact resistance of a linear poly(methyl methacrylate) denture-base polymer. PubMed: Influence of some humectants on the physical characteristics of solidified sodium stearate-based sticks. PubMed: Effect of polyethyleneglycols (PEG 600 and PEG 6000) and bovine serum albumin on myeloperoxidase-mediated release of [3H]-serotonin from rat peritoneal mast cells in vitro. PubMed: Electron microscopy of virus particles in ultrathin frozen sections.