peg-600
poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, (600 mol EO average molar ratio)
Identification
| Name | peg-600 |
| CAS Number | 25322-68-3 |
| FDA UNII | Search |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 1e+006 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | intravenous-dog LDLo 3000 mg/kg |
| Dermal Toxicity | subcutaneous-mouse LD50 18000 mg/kg |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'KIDNEY, URETER, AND BLADDER: HEMATURIA\nVASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION\nCARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION)']
Safety in Use
| Category | information only not used for fragrances or flavors |
| Recommendation for peg-600 usage levels up to | not for fragrance use. |
| Recommendation for peg-600 flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, (600 mol EO average molar ratio)
polyethylene glycol (600)
polyoxyethylene (600)
PubMed:
Development and Application of an MS(ALL)-Based Approach for the Quantitative Analysis of Linear Polyethylene Glycols in Rat Plasma by Liquid Chromatography Triple-Quadrupole/Time-of-Flight Mass Spectrometry.
PubMed:
Recovery of lignin peroxidase from submerged liquid fermentation of Amauroderma rugosum (Blume & T. Nees) Torrend using polyethylene glycol/salt aqueous two-phase system.
PubMed:
Asymmetric Catalytic 1,2-Hydroperoxidation of Isatin-Derived Ketimine with Hydrogen Peroxide in the Crowding Environment of PEGs.
PubMed:
Structure and Conformational Properties of d-Glucose/d-Galactose-Binding Protein in Crowded Milieu.
PubMed:
In vivo evaluation of a self-nanoemulsifying drug delivery system for curcumin.
PubMed:
Alendronate-anchored PEGylation of ceria nanoparticles promotes human hepatoma cell proliferation via AKT/ERK signaling pathways.
PubMed:
Peculiarities of the Super-Folder GFP Folding in a Crowded Milieu.
PubMed:
Eco-friendly PEG-based controlled release nano-formulations of Mancozeb: Synthesis and bioefficacy evaluation against phytopathogenic fungi Alternaria solani and Sclerotium rolfsii.
PubMed:
Generation of gas-phase ions from charged clusters: an important ionization step causing suppression of matrix and analyte ions in matrix-assisted laser desorption/ionization mass spectrometry.
PubMed:
Formulation, characterization, in vitro and in vivo evaluation of castor oil based self-nano emulsifying levosulpiride delivery systems.
PubMed:
Enhanced oral delivery of risperidone through a novel self-nanoemulsifying powder (SNEP) formulations: in-vitro and ex-vivo assessment.
PubMed:
Liquid PEG Polymers Containing Antioxidants: A Versatile Platform for Studying Oxygen-Sensitive Photochemical Processes.
PubMed:
Mechanisms of imiquimod skin penetration.
PubMed:
Development and evaluation of viscosity-enhanced nanocarrier (VEN) for oral insulin delivery.
PubMed:
Structure and stability of recombinant bovine odorant-binding protein: III. Peculiarities of the wild type bOBP unfolding in crowded milieu.
PubMed:
Effect of coating thickness of iron oxide nanoparticles on their relaxivity in the MRI.
PubMed:
Experimental Strategies to Bridge Large Tissue Gaps in the Injured Spinal Cord after Acute and Chronic Lesion.
PubMed:
Interrelationship between partition behavior of organic compounds and proteins in aqueous dextran-polyethylene glycol and polyethylene glycol-sodium sulfate two-phase systems.
PubMed:
Thyroid hormone (levothyroxine) replacement via the respiratory route by inhalation: in vitro exploratory studies.
PubMed:
Crack-free polydimethylsiloxane-bioactive glass-poly(ethylene glycol) hybrid monoliths with controlled biomineralization activity and mechanical property for bone tissue regeneration.
PubMed:
Lipid-polyethylene glycol based nano-ocular formulation of ketoconazole.
PubMed:
Microwave assisted efficient synthesis of diphenyl substituted pyrazoles using PEG-600 as solvent - A green approach.
PubMed:
Polyethylene glycol and divalent salt-induced DNA reentrant condensation revealed by single molecule measurements.
PubMed:
Positional impact of fluorescently modified G-tetrads within polymorphic human telomeric G-quadruplex structures.
PubMed:
Fabrication of triblock ABA type peptide dendrimer based on glutamic acid dimethyl ester and PEG as a potential nano drug delivery agent.
PubMed:
Cellulosic/wool pigment prints with remarkable antibacterial functionalities.
PubMed:
Purification, crystallization and preliminary X-ray analysis of a putative nucleotide phosphohydrolase, YpgQ, from Bacillus subtilis.
PubMed:
Formulation of fenofibrate liquisolid tablets using central composite design.
PubMed:
Devitrification and recrystallization of nanoparticle-containing glycerol and PEG-600 solutions.
PubMed:
Use of nonelectrolytes reveals the channel size and oligomeric constitution of the Borrelia burgdorferi P66 porin.
PubMed:
Characterization of a nonribosomal peptide antibiotic solid dispersion formulation by process analytical technologies sensors.
PubMed:
Development and characterization of dilutable self-microemulsifying premicroemulsion systems (SMEPMS) as templates for preparation of nanosized particulates.
PubMed:
Effect of salt additives on protein partition in polyethylene glycol-sodium sulfate aqueous two-phase systems.
PubMed:
Solvent-controlled halo-selective selenylation of aryl halides catalyzed by Cu(II) supported on Al2O3. A general protocol for the synthesis of unsymmetrical organo mono- and bis-selenides.
PubMed:
Synthetic evaluation of disulphide-bonded sarafotoxin on a poly(oxy ether) grafted dendrimeric poly(alkyl amine) support for polymer assisted organic synthesis.
PubMed:
Development of controlled release formulations of thiram employing amphiphilic polymers and their bioefficacy evaluation in seed quality enhancement studies.
PubMed:
Development and physico-mechanical characterization of carrageenan and poloxamer-based lyophilized matrix as a potential buccal drug delivery system.
PubMed:
Application of parylene for surface (polymer) enhanced laser desorption/ionization of synthetic polymers.
PubMed:
Study on Mixed Solvency Concept in Formulation Development of Aqueous Injection of Poorly Water Soluble Drug.
PubMed:
Non-ionic dendronized multiamphiphilic polymers as nanocarriers for biomedical applications.
PubMed:
Influence of hybrid inorganic/organic mesoporous and nanostructured materials on the cephalosporins' efficacy on different bacterial strains.
PubMed:
Development of lyophilization cycle and effect of excipients on the stability of catalase during lyophilization.
PubMed:
Influence of MRI contrast media on histamine release from mast cells.
PubMed:
Evaluation of water uptake and mechanical properties of blended polymer films for preparing gas-generated multiple-unit floating drug delivery systems.
PubMed:
Aqueous two-phase extraction for the purification of alkaline agarases from culture extracts of Pseudomonas aeruginosa AG LSL-11.
PubMed:
Poly(acrylic acid)/poly(ethylene glycol) adduct for attaining multifunctional cellulosic fabrics.
PubMed:
A high activity photocatalyst of hierarchical 3D flowerlike ZnO microspheres: synthesis, characterization and catalytic activity.
PubMed:
Enhanced cell uptake of superparamagnetic iron oxide nanoparticles through direct chemisorption of FITC-Tat-PEGâââ-b-poly(glycerol monoacrylate).
PubMed:
Bioefficacy evaluation of controlled release formulations based on amphiphilic nano-polymer of carbofuran against Meloidogyne incognita infecting tomato.
PubMed:
Crosslinked chitosan nanoparticle formulations for delivery from pressurized metered dose inhalers.
PubMed:
Novel films for drug delivery via the buccal mucosa using model soluble and insoluble drugs.
PubMed:
Biofunctionalization of titanium with PEG and anti-CD34 for hemocompatibility and stimulated endothelialization.
PubMed:
Self-assembly of amphiphilic glycoconjugates into lectin-adhesive nanoparticles.
PubMed:
Biocatalytic route to sugar-PEG-based polymers for drug delivery applications.
PubMed:
Controllable synthesis and luminescent properties of three-dimensional nanostructured CaWO4:Tb3+ microspheres.
PubMed:
Facile synthesis of 3D flowerlike CeO2 microspheres under mild condition with high catalytic performance for CO oxidation.
PubMed:
A novel cold-adapted lipase from Acinetobacter sp. XMZ-26: gene cloning and characterisation.
PubMed:
Pore size prediction of polyethersulfone ultrafiltration membranes using artificial neural networks.
PubMed:
PEGylated N-methyl-S-methyl dithiocarbazate as a new reagent for the high-yield preparation of nitrido Tc-99m and Re-188 radiopharmaceuticals.
PubMed:
Doxycycline hydrogels with reversible disulfide crosslinks for dermal wound healing of mustard injuries.
PubMed:
Impact of osmotic/matric stress and heat shock on environmental tolerance induction of bacterial biocontrol agents against Fusarium verticillioides.
PubMed:
Studies on the conformational change of adsorbed BSA onto a moderately hydrophobic surface at different denaturant concentrations and surface coverages.
PubMed:
Dual affinity method for plasmid DNA purification in aqueous two-phase systems.
PubMed:
Rapid identification of stabilisers in polypropylene using time-of-flight mass spectrometry and DART as ion source.
PubMed:
Effect of polyethylene glycol on the thermal stability of green fluorescent protein.
PubMed:
Preparation of TiO(2)/Ag colloids with ultraviolet resistance and antibacterial property using short chain polyethylene glycol.
PubMed:
Nitric oxide, actin reorganization and vacuoles change are involved in PEG 6000-induced stomatal closure in Vicia faba.
PubMed:
Temperature-sensitive biodegradable poly(ethylene glycol).
PubMed:
[DSC and FTIR study of adsorbed lysozyme on hydrophobic surface].
PubMed:
Liquid-liquid extraction of some lanthanide metal ions by polyoxyalkylene systems.
PubMed:
Mucoadhesive polymeric hydrogels for nasal delivery of acyclovir.
PubMed:
Affinity partitioning of plasmid DNA with a zinc finger protein.
PubMed:
Cholesterol binding to amyloid-beta fibrils: a TEM study.
PubMed:
Crystallization and preliminary X-ray characterization of queD from Bacillus subtilis, an enzyme involved in queuosine biosynthesis.
PubMed:
Preparation of plasmid DNA polyplexes from alkaline lysates by a two-step aqueous two-phase extraction process.
PubMed:
Aqueous two-phase recovery of bio-nanoparticles: a miniaturization study for the recovery of bacteriophage T4.
PubMed:
An approach for increasing the mass recovery of proteins derived from inclusion bodies in biotechnology.
PubMed:
Enhanced mixture analysis of poly(ethylene glycol) using high-field asymmetric waveform ion mobility spectrometry combined with fourier transform ion cyclotron resonance mass spectrometry.
PubMed:
Detection of lymphocystis disease virus (LCDV) in asymptomatic cultured gilt-head seabream (Sparus aurata, L.) using an immunoblot technique.
PubMed:
Towards an understanding of adsorption behaviour in non-aqueous systems: adsorption of poly(vinyl pyrrolidone) and poly(ethylene glycol) onto silica from 2H, 3H-perfluoropentane.
PubMed:
[Simultaneous purification of superoxide dismutase, catalase and hemoglobin from bovine erythrocyte lysate with PEG 600 as chaperon].
PubMed:
Explaining the phase behaviour of the pharmaceutically relevant polymers poly(ethylene glycol) and poly(vinyl pyrrolidone) in semi-fluorinated liquids.
PubMed:
Purification of plasmid DNA vectors by aqueous two-phase extraction and hydrophobic interaction chromatography.
PubMed:
[Spectrophotometric assay of polyethyene glycol in urine using ammonium ferrothiocyanate aqueous-chloroform system].
PubMed:
Physical characterizations of microemulsion systems using tocopheryl polyethylene glycol 1000 succinate (TPGS) as a surfactant for the oral delivery of protein drugs.
PubMed:
Polyethylene glycol-grafted bovine pericardium: a novel hybrid tissue resistant to calcification.
PubMed:
Synthesis and characterization of polyurethane and poly(ether urethane) nanocapsules using a new technique of interfacial polycondensation combined to spontaneous emulsification.
PubMed:
Formulation dependent pharmacokinetics, bioavailability and renal toxicity of a selective cyclooxygenase-1 inhibitor SC-560 in the rat.
PubMed:
Recovery of the proteose peptone component 3 from cheese whey in Reppal PES 100/polyethylene glycol aqueous two-phase systems.
PubMed:
Crystallization and preliminary X-ray diffraction studies of a novel alcohol dehydrogenase from the hyperthermophilic archaeon Aeropyrum pernix.
PubMed:
In vitro fibrillogenesis of the amyloid beta 1-42 peptide: cholesterol potentiation and aspirin inhibition.
PubMed:
Isolation of plasmid DNA from cell lysates by aqueous two-phase systems.
PubMed:
Biocompatibility evaluation of ePTFE membrane modified with PEG in atmospheric pressure glow discharge.
PubMed:
Involvement of osmotic cell shrinkage on the proton extrusion rate in Saccharomyces cerevisiae.
PubMed:
The effects of plasticizers and titanium dioxide on the properties of poly(vinyl alcohol) coatings.
PubMed:
Requirements for osmosensing and osmotic activation of transporter ProP from Escherichia coli.
PubMed:
The use of 1H-NMR spectroscopy and refractometry for investigation of the distribution of nonelectrolytes of N-alcohol series between human red blood cells and extracellular medium.
PubMed:
Evaluation of absorbability of poorly water-soluble drugs: validity of the use of additives.
PubMed:
Study of phase behavior of poly(ethylene glycol)-polysorbate 80 and poly(ethylene glycol)-polysorbate 80-water mixtures.
PubMed:
Site-specific insulin conjugates with enhanced stability and extended action profile.
PubMed:
Water and temperature relations of growth of the entomogenous fungi beauveria bassiana, metarhizium anisopliae, and paecilomyces farinosus
PubMed:
The effect of formulation parameters on the size of poly-((2-dimethylamino)ethyl methacrylate)-plasmid complexes.
PubMed:
[Capillary free zone electrophoresis of globin chains].
PubMed:
Use of aqueous two-phase systems for in situ extraction of water soluble antibiotics during their synthesis by enzymes immobilized on porous supports.
PubMed:
Centrifugal partition chromatographic reaction for the production of chiral amino acids.
PubMed:
Enhanced diffractivity of phosphoglucomutase crystals. Use of an alternative cryocrystallographic procedure.
PubMed:
Permeability studies of cellulose acetate free films for transdermal use: influence of plasticizers.
PubMed:
Synthesis, structure-activity relationships, and the effect of polyethylene glycol on inhibitors of phosphatidylinositol-specific phospholipase C from Bacillus cereus.
PubMed:
Crystallization and preliminary diffraction studies of NodL, a rhizobial O-acetyl-transferase involved in the host-specific nodulation of legume roots.
PubMed:
Improved oral absorption of L-365,260, a poorly soluble drug.
PubMed:
Functional role of follicular cells in the generation of osmolarity-dependent Cl- currents in Xenopus follicles.
PubMed:
Crystallization and preliminary X-ray diffraction studies of complexes between an influenza hemagglutinin and Fab fragments of two different monoclonal antibodies.
PubMed:
Effect of polyol molecular weight on the physical properties and haemocompatibility of polyurethanes containing polyethylene oxide macroglycols.
PubMed:
Extraction of cephalosporin C from whole broth and separation of desacetyl cephalosporin C by aqueous two-phase partition.
PubMed:
Protection from reperfusion-induced arrhythmias by polyethylene glycol 600.
PubMed:
Crystallization of phosphatidylinositol-specific phospholipase C from Bacillus cereus.
PubMed:
Purification, crystallization and preliminary X-ray analysis of the 3-phosphoglycerate kinase from Bacillus stearothermophilus.
PubMed:
Microencapsulation of solid dispersions: release of griseofulvin from griseofulvin:phospholipid coprecipitates in microspheres.
PubMed:
Self-emulsifying drug delivery systems: formulation and biopharmaceutic evaluation of an investigational lipophilic compound.
PubMed:
[The use of monolaurates for removing endotoxins from preparations of cell-free pertussis vaccine].
PubMed:
High-performance liquid chromatographic determination of PEG 600 in human urine.
PubMed:
[Fusion of protoplasts of inactive variants of 2 producers of actinomycin C and the biosynthesis of an antibiotic of non- actinomycin nature].
PubMed:
Absorption of polyethylene glycols 600 through 2000: the molecular weight dependence of gastrointestinal and nasal absorption.
PubMed:
The molecular weight dependence of nasal absorption: the effect of absorption enhancers.
PubMed:
Rapid low molecular weight polyethylene glycol embedding protocol for immunocytochemistry.
PubMed:
The effect of cross-linking agents on the impact resistance of a linear poly(methyl methacrylate) denture-base polymer.
PubMed:
Influence of some humectants on the physical characteristics of solidified sodium stearate-based sticks.
PubMed:
Effect of polyethyleneglycols (PEG 600 and PEG 6000) and bovine serum albumin on myeloperoxidase-mediated release of [3H]-serotonin from rat peritoneal mast cells in vitro.
PubMed:
Electron microscopy of virus particles in ultrathin frozen sections.