myristyl nicotinate

3-pyridinecarboxylic acid, tetradecyl ester

CAS: 273203-62-6 C20 H33 N O2 MW: 319.48841000

Identification

Namemyristyl nicotinate
CAS Number273203-62-6
FDA UNII8QWM6I035C
Molecular FormulaC20 H33 N O2
Molecular Weight319.48841000
Nikkaji NumberJ2.266.334H
XlogP37.90 (est)

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 411.73 °C. @ 760.00 mm Hg (est)
Flash Point 397.00 °F. TCC ( 202.80 °C. ) (est)
logP (o/w) 7.790 (est)
Soluble in water, 0.009464 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Useshair conditioning

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorycosmetic agents
Recommendation for myristyl nicotinate usage levels up tonot for fragrance use.
Recommendation for myristyl nicotinate flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

myristylnicotinate nicotinic acid myristyl ester nicotinic acid, tetradecyl ester 3- pyridinecarboxylic acid, tetradecyl ester tetradecan-1-ol, nicotinate tetradecyl nicotinate tetradecyl pyridine-3-carboxylate PubMed: Preparation and characterization of microemulsion formulations of nicotinic acid and its prodrugs for transdermal delivery. PubMed: Formulation compatibility of myristyl nicotinate with drugs used to treat dermatological conditions involving an impaired skin barrier. PubMed: Gateways to clinical trials. PubMed: Effect of myristyl nicotinate on retinoic acid therapy for facial photodamage. PubMed: A topical lipophilic niacin derivative increases NAD, epidermal differentiation and barrier function in photodamaged skin. PubMed: Analysis and stability study of myristyl nicotinate in dermatological preparations by high-performance liquid chromatography. PubMed: Simultaneous determination of myristyl nicotinate, nicotinic acid, and nicotinamide in rabbit plasma by liquid chromatography-tandem mass spectrometry using methyl ethyl ketone as a deproteinization solvent.