bryonolic acid

D:C-friedoolean-8-en-29-oic acid, 3-hydroxy-, (3beta,20beta)-

CAS: 24480-45-3 C30 H48 O3 MW: 456.71016000

Identification

Namebryonolic acid
CAS Number24480-45-3
FDA UNIIJ7YR6A878I
Molecular FormulaC30 H48 O3
Molecular Weight456.71016000
Nikkaji NumberJ735.951I

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 553.28 °C. @ 760.00 mm Hg (est)
Flash Point 576.00 °F. TCC ( 302.50 °C. ) (est)
logP (o/w) 8.404 (est)
Soluble in water, 0.0003527 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesskin conditioning - emollient

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryemollients
Recommendation for bryonolic acid usage levels up tonot for fragrance use.
Recommendation for bryonolic acid flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

gourd calabash gourd luffa plant momordica dioica olive sandoricum indicum watermelon plant watermelon tissue culture

Synonyms

20-epi- bryonolic acid D:C- friedoolean-8-en-29-oic acid, 3-hydroxy-, (3beta,20beta)- (2S,4aS,6aS,8aR,10S,12aS,14aS,14bR)-10- hydroxy-2,4a,6a,9,9,12a,14a-heptamethyl-1,3,4,5,6,7,8,8a,10,11,12,13,14,14b-tetradecahydropicene-2-carboxylic acid PubMed: Approach for expanding triterpenoid complexity via divergent Norrish-Yang photocyclization. PubMed: Bryonolic acid transcriptional control of anti-inflammatory and antioxidant genes in macrophages in vitro and in vivo. PubMed: Bryonolic acid: a large-scale isolation and evaluation of heme oxygenase 1 expression in activated macrophages. PubMed: New cucurbitane-type triterpenoids from Bryonia aspera. PubMed: Characterization of a rare triterpenoid and minor phenolic compounds in the root bark of Anisophyllea dichostyla R. Br. PubMed: Cytotoxic properties of root extract and fruit juice of Trichosanthes cucumerina. PubMed: Crystal structure of acetyl 29-methyl-29-methylidene-D:C-friedoolean-8-en-3beta-ol. PubMed: Arbuscular mycorrhizal fungus-promoted accumulation of two new triterpenoids in cucumber roots. PubMed: Relative population of S-form and F-form conformers of bryonolic acid and its derivatives in equilibrium in CdCl3 solutions. PubMed: Molecular cloning and characterization of isomultiflorenol synthase, a new triterpene synthase from Luffa cylindrica, involved in biosynthesis of bryonolic acid. PubMed: Triterpenoid p-aminobenzoates from the seeds of zucchini. PubMed: Modulation of programmed cell death by medicinal plants. PubMed: Cytotoxic activity of bryonolic acid isolated from transformed hairy roots of Trichosanthes kirilowii var. japonica. PubMed: Bryonolic acid production in hairy roots of Trichosanthes kirilowii Max. var Japonica Kitam. Transformed with Agrobacterium rhizogenes and its cytotoxic activity. PubMed: [Studies on the chemical constituents of Trichosanthes hupehensis C.Y. Cheng et Yueh]. PubMed: Intracellular distribution of the hydrophobic triterpene, bryonolic acid, in cultured cells of Luffa cylindrica L. PubMed: Production of an anti-allergic triterpene bryonolic acid, by plant cell cultures. PubMed: 7-Oxodihydrokarounidiol [7-oxo-D:C-friedo-olean-8-ene-3 alpha,29-diol], a novel triterpene from Trichosanthes kirilowii. PubMed: Anti-allergic effect of bryonolic acid from Luffa cylindrica cell suspension cultures. PubMed: [Studies on the constituents of "Trichosanthes root". IV. Constituents of roots of Trichosanthes multiloba Miq., Trichosanthes miyagii Hay. and Chinese crude drug "karo-kon"]. PubMed: [Studies on the constituents of trichosanthes root. III. Constituents of roots of Trichosanthes bracteata Voigt]. PubMed: [Studies on the constituents of trichosanthes root. I. Constituents of roots of Trichosanthes kirilowii Maxim. var. japonicum Kitam]. PubMed: Biosynthesis of cucurbitacins in Bryonia dioica seedlings. PubMed: Structure of bryonolic acid.