bryonolic acid
D:C-friedoolean-8-en-29-oic acid, 3-hydroxy-, (3beta,20beta)-
Identification
| Name | bryonolic acid |
| CAS Number | 24480-45-3 |
| FDA UNII | J7YR6A878I |
| Molecular Formula | C30 H48 O3 |
| Molecular Weight | 456.71016000 |
| Nikkaji Number | J735.951I |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 553.28 °C. @ 760.00 mm Hg (est) |
| Flash Point | 576.00 °F. TCC ( 302.50 °C. ) (est) |
| logP (o/w) | 8.404 (est) |
| Soluble in | water, 0.0003527 mg/L @ 25 °C (est) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | skin conditioning - emollient |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | emollients |
| Recommendation for bryonolic acid usage levels up to | not for fragrance use. |
| Recommendation for bryonolic acid flavor usage levels up to | not for flavor use. |
BOC Sciences
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Potential Uses
Natural Occurrence
Synonyms
20-epi-
bryonolic acid
D:C-
friedoolean-8-en-29-oic acid, 3-hydroxy-, (3beta,20beta)-
(2S,4aS,6aS,8aR,10S,12aS,14aS,14bR)-10-
hydroxy-2,4a,6a,9,9,12a,14a-heptamethyl-1,3,4,5,6,7,8,8a,10,11,12,13,14,14b-tetradecahydropicene-2-carboxylic acid
PubMed:
Approach for expanding triterpenoid complexity via divergent Norrish-Yang photocyclization.
PubMed:
Bryonolic acid transcriptional control of anti-inflammatory and antioxidant genes in macrophages in vitro and in vivo.
PubMed:
Bryonolic acid: a large-scale isolation and evaluation of heme oxygenase 1 expression in activated macrophages.
PubMed:
New cucurbitane-type triterpenoids from Bryonia aspera.
PubMed:
Characterization of a rare triterpenoid and minor phenolic compounds in the root bark of Anisophyllea dichostyla R. Br.
PubMed:
Cytotoxic properties of root extract and fruit juice of Trichosanthes cucumerina.
PubMed:
Crystal structure of acetyl 29-methyl-29-methylidene-D:C-friedoolean-8-en-3beta-ol.
PubMed:
Arbuscular mycorrhizal fungus-promoted accumulation of two new triterpenoids in cucumber roots.
PubMed:
Relative population of S-form and F-form conformers of bryonolic acid and its derivatives in equilibrium in CdCl3 solutions.
PubMed:
Molecular cloning and characterization of isomultiflorenol synthase, a new triterpene synthase from Luffa cylindrica, involved in biosynthesis of bryonolic acid.
PubMed:
Triterpenoid p-aminobenzoates from the seeds of zucchini.
PubMed:
Modulation of programmed cell death by medicinal plants.
PubMed:
Cytotoxic activity of bryonolic acid isolated from transformed hairy roots of Trichosanthes kirilowii var. japonica.
PubMed:
Bryonolic acid production in hairy roots of Trichosanthes kirilowii Max. var Japonica Kitam. Transformed with Agrobacterium rhizogenes and its cytotoxic activity.
PubMed:
[Studies on the chemical constituents of Trichosanthes hupehensis C.Y. Cheng et Yueh].
PubMed:
Intracellular distribution of the hydrophobic triterpene, bryonolic acid, in cultured cells of Luffa cylindrica L.
PubMed:
Production of an anti-allergic triterpene bryonolic acid, by plant cell cultures.
PubMed:
7-Oxodihydrokarounidiol [7-oxo-D:C-friedo-olean-8-ene-3 alpha,29-diol], a novel triterpene from Trichosanthes kirilowii.
PubMed:
Anti-allergic effect of bryonolic acid from Luffa cylindrica cell suspension cultures.
PubMed:
[Studies on the constituents of "Trichosanthes root". IV. Constituents of roots of Trichosanthes multiloba Miq., Trichosanthes miyagii Hay. and Chinese crude drug "karo-kon"].
PubMed:
[Studies on the constituents of trichosanthes root. III. Constituents of roots of Trichosanthes bracteata Voigt].
PubMed:
[Studies on the constituents of trichosanthes root. I. Constituents of roots of Trichosanthes kirilowii Maxim. var. japonicum Kitam].
PubMed:
Biosynthesis of cucurbitacins in Bryonia dioica seedlings.
PubMed:
Structure of bryonolic acid.