maslinic acid

crategolic acid (4aS,6aR,6aS,6bR,8aR,10R,11R,12aR,14bS)-10,11- dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid maslic acid maslinicacid olean-12-en-28-oic acid, 2,3-dihydroxy-, olean-12-en-28-oic acid, 2,3-dihydroxy-, (2alpha,3beta)- PubMed: Maslinic Acid Induces Mitochondrial Apoptosis and Suppresses HIF-1α Expression in A549 Lung Cancer Cells under Normoxic and Hypoxic Conditions. PubMed: In vitro effects of triterpenic acids from olive leaf extracts on the mitochondrial membrane potential of promastigote stage of Leishmania spp. PubMed: Protective effects of maslinic acid against alcohol-induced acute liver injury in mice. PubMed: Antibacterial oleanane-type triterpenoids from pericarps of Akebia trifoliata. PubMed: Maslinic acid, a natural phytoalexin-type triterpene from olives--a promising nutraceutical? PubMed: Maslinic acid activates mitochondria-dependent apoptotic pathway in cardiac carcinoma. PubMed: Population pharmacokinetics of maslinic acid, a triterpene from olives, after intravenous and oral administration in rats. PubMed: Solid-phase library synthesis of bi-functional derivatives of oleanolic and maslinic acids and their cytotoxicity on three cancer cell lines. PubMed: Phytochemistry and bioactivity of aromatic and medicinal plants from the genus Agastache (Lamiaceae). PubMed: Maslinic acid modulates glycogen metabolism by enhancing the insulin signaling pathway and inhibiting glycogen phosphorylase. PubMed: Maslinic acid induced apoptosis in bladder cancer cells through activating p38 MAPK signaling pathway. PubMed: Maslinic acid protects vascular smooth muscle cells from oxidative stress through Akt/Nrf2/HO-1 pathway. PubMed: Oleanolic and maslinic acid sensitize soft tissue sarcoma cells to doxorubicin by inhibiting the multidrug resistance protein MRP-1, but not P-glycoprotein. PubMed: Semi-synthesis of acylated triterpenes from olive-oil industry wastes for the development of anticancer and anti-HIV agents. PubMed: Membrane damaging activity of a maslinic acid analog. PubMed: Four new triterpenoids isolated from the resin of Garcinia hanburyi. PubMed: Antioxidant effects of maslinic acid in livers, hearts and kidneys of streptozotocin-induced diabetic rats: effects on kidney function. PubMed: Bioactive properties of the main triterpenes found in olives, virgin olive oil, and leaves of Olea europaea. PubMed: Effects of Syzygium aromaticum-derived triterpenes on postprandial blood glucose in streptozotocin-induced diabetic rats following carbohydrate challenge. PubMed: Towards cytotoxic and selective derivatives of maslinic acid. PubMed: Esters and amides of maslinic acid trigger apoptosis in human tumor cells and alter their mode of action with respect to the substitution pattern at C-28. PubMed: Maslinic acid and its in vitro anti-neoplastic effects. PubMed: Liquid chromatography-mass spectrometry determination in plasma of maslinic acid, a bioactive compound from Olea europaea L. PubMed: Antitumour activity on extrinsic apoptotic targets of the triterpenoid maslinic acid in p53-deficient Caco-2 adenocarcinoma cells. PubMed: Biotransformation of oleanolic and maslinic acids by Rhizomucor miehei. PubMed: Time course of pentacyclic triterpenoids from fruits and leaves of olive tree (Olea europaea L.) cv. Picual and cv. Cornezuelo during ripening. PubMed: [Chemical constituents of Rabdosia japonica var. glaucocalyx and their anti-complementary activity]. PubMed: Antiallodynic and analgesic effects of maslinic acid, a pentacyclic triterpenoid from Olea europaea. PubMed: [Protective effect of maslinic acid preconditioning against oxygen-glucose deprivation- induced injuries in embryonic rat cortical neurons]. PubMed: Maslinic acid-enriched diet decreases intestinal tumorigenesis in Apc(Min/+) mice through transcriptomic and metabolomic reprogramming. PubMed: Maslinic acid, a triterpenic anti-tumoural agent, interferes with cytoskeleton protein expression in HT29 human colon-cancer cells. PubMed: Anti-Proliferative Activities and Apoptosis Induction by Triterpenes Derived from Eriobotrya japonica in Human Leukemia Cell Lines. PubMed: Chemical constituents of flowers and fruits of Rabdosia excisa. PubMed: Assessment of the safety of maslinic acid, a bioactive compound from Olea europaea L. PubMed: Simultaneous determination of seven major triterpenoids in Pyrola decorata H. Andres by LC-MS method. PubMed: [Non-anthraquinones constituents from the roots of Knoxia valerianoides]. PubMed: A simple GC-MS method for the screening of betulinic, corosolic, maslinic, oleanolic and ursolic acid contents in commercial botanicals used as food supplement ingredients. PubMed: Determination of maslinic acid, a pentacyclic triterpene from olives, in rat plasma by high-performance liquid chromatography. PubMed: [Chemical constituents from Sambucus chinensis]. PubMed: Maslinic acid protects against isoproterenol-induced cardiotoxicity in albino Wistar rats. PubMed: Bioavailability, distribution, and antioxidative effects of selected triterpenes in mice. PubMed: Suppressive effect of maslinic acid on PMA-induced protein kinase C in human B-lymphoblastoid cells. PubMed: Efficacy of bioactive compounds from extra virgin olive oil to modulate atherosclerosis development. PubMed: Maslinic acid inhibits the metastatic capacity of DU145 human prostate cancer cells: possible mediation via hypoxia-inducible factor-1α signalling. PubMed: New terpenes from Salvia palaestina Benth. and Salvia syriaca L. growing wild in Jordan. PubMed: Nonsterol Triterpenoids as Major Constituents of Olea europaea. PubMed: A new triterpenoid from the rhizomes of Nelumbo nucifera. PubMed: [Study on the triterpenoids from the fruits of Ligustrum lucidum]. PubMed: Unusual isomeric corniculatolides from mangrove, Aegiceras corniculatum. PubMed: Towards an efficient protocol for the determination of triterpenic acids in olive fruit: a comparative study of drying and extraction methods. PubMed: [Chemical constituents of Swertia hispidicalyx]. PubMed: Targeting inflammatory pathways by triterpenoids for prevention and treatment of cancer. PubMed: [Chemical constituents about the stem of Rabdosia excisa]. PubMed: Maslinic acid derivatives induce significant apoptosis in b16f10 murine melanoma cells. PubMed: Anti-inflammatory effects of maslinic acid, a natural triterpene, in cultured cortical astrocytes via suppression of nuclear factor-kappa B. PubMed: Proteomic analysis of the molecular response of Raji cells to maslinic acid treatment. PubMed: Maslinic acid, a natural triterpenoid compound from Olea europaea, protects cortical neurons against oxygen-glucose deprivation-induced injury. PubMed: [Studies on the chemical constituents from the leave of Paulownia tomentosa]. PubMed: Maslinic acid, a natural inhibitor of glycogen phosphorylase, reduces cerebral ischemic injury in hyperglycemic rats by GLT-1 up-regulation. PubMed: Proteomics in the liver of gilthead sea bream (Sparus aurata) to elucidate the cellular response induced by the intake of maslinic acid. PubMed: Effect of olive pomace extracts on hyperlipidaemia. PubMed: Identification and determination of carboxylic acids in food samples using 2-(2-(anthracen-10-yl)-1H-phenanthro[9,10-d]imidazol-1-yl)ethyl 4-methylbenzenesulfonate (APIETS) as labeling reagent by HPLC with FLD and APCI/MS. PubMed: Multi-targeted activity of maslinic acid as an antimalarial natural compound. PubMed: Simultaneous qualitative and quantitative analysis of triterpenic acids, saponins and flavonoids in the leaves of two Ziziphus species by HPLC-PDA-MS/ELSD. PubMed: The natural triterpene maslinic acid induces apoptosis in HT29 colon cancer cells by a JNK-p53-dependent mechanism. PubMed: Parasitostatic effect of maslinic acid. II. Survival increase and immune protection in lethal Plasmodium yoelii-infected mice. PubMed: [Triterpenoids and triterpenoid saponins of Viscum liquidambaricolum]. PubMed: Parasitostatic effect of maslinic acid. I. Growth arrest of Plasmodium falciparum intraerythrocytic stages. PubMed: Development of a new HPLC method with precolumn fluorescent derivatization for rapid, selective and sensitive detection of triterpenic acids in fruits. PubMed: Triterpenoid saponins from Symplocos lancifolia. PubMed: Maslinic acid induces apoptosis in salivary gland adenoid cystic carcinoma cells by Ca2+-evoked p38 signaling pathway. PubMed: Phenylpropanoids from the stem bark of Jacaranda mimosaefolia. PubMed: Antiangiogenic potential of three triterpenic acids in human liver cancer cells. PubMed: Antioxidant, antiproliferative, and pro-apoptotic capacities of pentacyclic triterpenes found in the skin of olives on MCF-7 human breast cancer cells and their effects on DNA damage. PubMed: Astrocytic glutamate transporter-dependent neuroprotection against glutamate toxicity: an in vitro study of maslinic acid. PubMed: [Studies on the chemical constituents of Ficus microcarpa]. PubMed: Pentacyclic triterpenoids and ceramide mediate the vasorelaxant activity of Vitex cienkowskii via involvement of NO/cGMP pathway in isolated rat aortic rings. PubMed: Maslinic acid suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss by regulating RANKL-mediated NF-κB and MAPK signaling pathways. PubMed: Isolation and identification of intestinal CYP3A inhibitors from cranberry (Vaccinium macrocarpon) using human intestinal microsomes. PubMed: Pharmacological manipulation of brain glycogenolysis as a therapeutic approach to cerebral ischemia. PubMed: Chemical constituents with free-radical-scavenging activities from the stem of Microcos paniculata. PubMed: Pentacyclic triterpenoids from olive fruit and leaf. PubMed: Cancer chemopreventive activity of maslinic acid: suppression of COX-2 expression and inhibition of NF-κB and AP-1 activation in Raji cells. PubMed: Antioxidant and antiatherogenic activities of pentacyclic triterpenic diols and acids. PubMed: Anticoccidial activity of maslinic acid against infection with Eimeria tenella in chickens. PubMed: Chemopreventive properties of phytosterols and maslinic acid extracted from Coleus tuberosus in inhibiting the expression of EBV early-antigen in Raji cells. PubMed: Action of a pentacyclic triterpenoid, maslinic acid, against Toxoplasma gondii. PubMed: Maslinic acid potentiates the anti-tumor activity of tumor necrosis factor alpha by inhibiting NF-kappaB signaling pathway. PubMed: Two new secoiridoid glycosides from the leaves of Olea europaea L. PubMed: Bioactive compounds with added value prepared from terpenes contained in solid wastes from the olive oil industry. PubMed: Different pathways for the deoxygenation of the A-ring of natural triterpene compounds. PubMed: [Chemical constituents of roots of Boehmeria nivea]. PubMed: [Determination of triterpenoid acids in leaves of Eriobotrya japonica collected at in different seasons]. PubMed: Synthesis and biological evaluation of heterocyclic ring-substituted maslinic acid derivatives as novel inhibitors of protein tyrosine phosphatase 1B. PubMed: Transformed cell suspension culture of Galphimia glauca producing sedative nor-friedelanes. PubMed: Fruit quality and olive leaf and stone addition affect Picual virgin olive oil triterpenic content. PubMed: Triterpenic content and chemometric analysis of virgin olive oils from forty olive cultivars. PubMed: Effects of maslinic acid, a natural triterpene, on glycogen metabolism in cultured cortical astrocytes. PubMed: [Chemical constituents from herbs of Swertia mileensis]. PubMed: Novel binding studies of human serum albumin with trans-feruloyl maslinic acid. PubMed: [Studies on the triterpenes from loquat leaf (Eriobotrya japonica)]. PubMed: Solution- and solid-phase synthesis and anti-HIV activity of maslinic acid derivatives containing amino acids and peptides. PubMed: Triterpene acids isolated from Lagerstroemia speciosa leaves as alpha-glucosidase inhibitors. PubMed: Triterpenoic acids of Prunella vulgaris var. lilacina and their cytotoxic activities in vitro. PubMed: Apolipoprotein E determines the hepatic transcriptional profile of dietary maslinic acid in mice. PubMed: Medicinal flowers. XXIII. New taraxastane-type triterpene, punicanolic acid, with tumor necrosis factor-alpha inhibitory activity from the flowers of Punica granatum. PubMed: Practical synthesis of bredemolic acid, a natural inhibitor of glycogen phosphorylase. PubMed: Maslinic acid, a natural triterpene from Olea europaea L., induces apoptosis in HT29 human colon-cancer cells via the mitochondrial apoptotic pathway. PubMed: Anti-inflammatory and antioxidant activities and constituents of Platostoma africanum P. Beauv. PubMed: Evaluation of gastroprotective activity of Plinia edulis (Vell.) Sobral (Myrtaceae) leaves in rats. PubMed: Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies. PubMed: Antiproliferative and apoptosis-inducing effects of maslinic and oleanolic acids, two pentacyclic triterpenes from olives, on HT-29 colon cancer cells. PubMed: Aldose-reductase- and protein-glycation-inhibitory principles from the whole plant of Duchesnea chrysantha. PubMed: Bioactivity-guided isolation of the active compounds from Rosa nutkana and quantitative analysis of ascorbic acid by HPLC. PubMed: Maslinic acid reduces blood glucose in KK-Ay mice. PubMed: Maslinic acid added to the diet increases growth and protein-turnover rates in the white muscle of rainbow trout (Oncorhynchus mykiss). PubMed: Antielastase and free radical scavenging activities of compounds from the stems of Cornus kousa. PubMed: Tyrosinase inhibitory pentacyclic triterpenes and analgesic and spasmolytic activities of methanol extracts of Rhododendron collettianum. PubMed: Inhibition of DNA topoisomerase I and growth inhibition of human cancer cell lines by an oleanane from Junellia aspera (Verbenaceae). PubMed: Triterpenoids isolated from apple peels have potent antiproliferative activity and may be partially responsible for apple's anticancer activity. PubMed: Production of triterpene acids by cell suspension cultures of Olea europaea. PubMed: Acidic triterpenes compromise growth and survival of astrocytoma cell lines by regulating reactive oxygen species accumulation. PubMed: Remote hydroxylation of methyl groups by regioselective cyclopalladation. Partial synthesis of hyptatic acid-A. PubMed: Formation of triterpenoids throughout Olea europaea fruit ontogeny. PubMed: Modulation of cytokine secretion by pentacyclic triterpenes from olive pomace oil in human mononuclear cells. PubMed: [Triterpenes from herb of Potentilla chinesis]. PubMed: Triterpenoids from Hippophae rhamnoides L. and their nitric oxide production-inhibitory and DPPH radical-scavenging activities. PubMed: New glycosides from Tetracentron sinense and their cytotoxic activity. PubMed: (2Alpha,3beta)-2,3-dihydroxyolean-12-en-28-oic acid, a new natural triterpene from Olea europea, induces caspase dependent apoptosis selectively in colon adenocarcinoma cells. PubMed: Olive fruit extracts inhibit proliferation and induce apoptosis in HT-29 human colon cancer cells. PubMed: Maslinic acid as a feed additive to stimulate growth and hepatic protein-turnover rates in rainbow trout (Onchorhynchus mykiss). PubMed: Secondary metabolites from the wood bark of Durio zibethinus and Durio kutejensis. PubMed: Constituents of the flowers of Punica granatum. PubMed: Diterpenes from Leucas aspera inhibiting prostaglandin-induced contractions. PubMed: An efficient chemical method for separation of corsolic acid from its isomeric maslinic acid. PubMed: New triterpenoids isolated from the root bark of Ulmus pumila L. PubMed: Production of triterpenoids in liquid-cultivated hairy roots of Galphimia glauca. PubMed: Triterpenic compounds from "orujo" olive oil elicit vasorelaxation in aorta from spontaneously hypertensive rats. PubMed: Supressive effect of maslinic acid from pomace olive oil on oxidative stress and cytokine production in stimulated murine macrophages. PubMed: Pentacyclic triterpenes. Part 2: Synthesis and biological evaluation of maslinic acid derivatives as glycogen phosphorylase inhibitors. PubMed: Pentacyclic triterpenes. Part 1: the first examples of naturally occurring pentacyclic triterpenes as a new class of inhibitors of glycogen phosphorylases. PubMed: Triterpenoids from the flower of Campsis grandiflora K. Schum. as human acyl-CoA: cholesterol acyltransferase inhibitors. PubMed: [Studies on chemical constituents in fruit of Rubus chingii]. PubMed: Novel ceramides and a new glucoceramide from the roots of Incarvillea arguta. PubMed: Anti-complementary activity of triterpenoides from fruits of Zizyphus jujuba. PubMed: Antitumor-promoting constituents from Chaenomeles sinensis KOEHNE and their activities in JB6 mouse epidermal cells. PubMed: Antioxidant activity of maslinic acid, a triterpene derivative obtained from Olea europaea. PubMed: Epoxides, cyclic sulfites, and sulfate from natural pentacyclic triterpenoids: theoretical calculations and chemical transformations. PubMed: Production of bioactive triterpenes by Eriobotrya japonica calli. PubMed: Phytochemical study and anti-inflammatory properties of Lampaya hieronymi Schum. ex Moldenke. PubMed: Antimicrobial triterpenoids from Licania heteromorpha. PubMed: Cytotoxic triterpenes from stem bark of Physocarpus intermedius. PubMed: Two glycosides from the stem bark of Tetracentron sinense. PubMed: Flavonoids and terpenoids from Luma gayana (Barn.) Burret. PubMed: DNA polymerase beta inhibitors from Tetracera boiviniana. PubMed: Anti-HIV triterpene acids from Geum japonicum. PubMed: Antiviral activity of new triterpenic derivatives. PubMed: Screening of plant constituents for effect on glucose transport activity in Ehrlich ascites tumour cells. PubMed: [Studies on the chemical constituents from roots of Agastache rugosa]. PubMed: Triterpene saponins from Cylicodiscus gabunensis. PubMed: Cytotoxic triterpenes from a Chinese medicine, Goreishi.