hypochlorous acid
chloroalcohol
Identification
| Name | hypochlorous acid |
| CAS Number | 7790-92-3 |
| EINECS | 232-232-5 |
| FDA UNII | 712K4CDC10 |
| Molecular Formula | Cl H O |
| Molecular Weight | 52.45917000 |
| Nikkaji Number | J202.839E |
Regulatory
| FDA/DG SANTE Petitions, Reviews, Notices | FCN 1176 |
| FDA Mainterm (IAUFC) | 7790-92-3 ; HYPOCHLOROUS ACID |
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Flash Point | 32.00 °F. TCC ( 0.00 °C. ) (est) |
| logP (o/w) | 0.710 (est) |
| Soluble in | water, 1e+006 mg/L @ 25 °C (est) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | antiseborrhoeic agents |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | antiseborrhoeic agents |
| Recommendation for hypochlorous acid usage levels up to | not for fragrance use. |
| Recommendation for hypochlorous acid flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
chloranol
chloroalcohol
PubMed:
C-phycocyanin prevents cisplatin-induced nephrotoxicity through inhibition of oxidative stress.
PubMed:
Advanced oxidation protein products are generated by bovine neutrophils and inhibit free radical production in vitro.
PubMed:
4-methylcoumarin derivatives inhibit human neutrophil oxidative metabolism and elastase activity.
PubMed:
Protection of flavonoids against hypochlorite-induced protein modifications.
PubMed:
Antioxidant activity and inhibitory effects of lead (Leucaena leucocephala) seed extracts against lipid oxidation in model systems.
PubMed:
Phytochemical profile of a blend of black chokeberry and lemon juice with cholinesterase inhibitory effect and antioxidant potential.
PubMed:
Carotenoids and phenolic compounds from Solanum sessiliflorum, an unexploited Amazonian fruit, and their scavenging capacities against reactive oxygen and nitrogen species.
PubMed:
Discrimination of infectious hepatitis A viruses by propidium monoazide real-time RT-PCR.
PubMed:
Antiviral activity of Ecasol against feline calicivirus, a surrogate of human norovirus.
PubMed:
Sensitive and simple determination of bromate in foods disinfected with hypochlorite reagents using high performance liquid chromatography with post-column derivatization.
PubMed:
Scavenging capacity of marine carotenoids against reactive oxygen and nitrogen species in a membrane-mimicking system.
PubMed:
Microbicidal effect of weak acid hypochlorous solution on various microorganisms.
PubMed:
Antioxidant characteristics of extracts from cereal residues by their subcritical water treatment.
PubMed:
Hypohalous acid-mediated halogenation of resveratrol and its role in antioxidant and antimicrobial activities.
PubMed:
Semicarbazide in selected bird's nest products.
PubMed:
Enhanced inactivation of Salmonella and Pseudomonas biofilms on stainless steel by use of T-128, a fresh-produce washing aid, in chlorinated wash solutions.
PubMed:
New beverages of lemon juice enriched with the exotic berries maqui, açaıÌ, and blackthorn: bioactive components and in vitro biological properties.
PubMed:
Transmission electron microscopic analysis showing structural changes to bacterial cells treated with electrolyzed water and an acidic sanitizer.
PubMed:
Laccase- and chloroperoxidase-nanotube paint composites with bactericidal and sporicidal activity.
PubMed:
Effect of anolyte on background microflora, Salmonella, and Listeria monocytogenes on catfish fillets.
PubMed:
Protective Effect of γ-Irradiation Against Hypochlorous Acid-Induced Haemolysis in Human Erythrocytes.
PubMed:
The real-time-based assessment of the microbial killing by the antimicrobial compounds of neutrophils.
PubMed:
Comparison of different washing treatments for reducing pathogens on orange surfaces and for preventing the transfer of bacterial pathogens to fresh-squeezed orange juice.
PubMed:
Amelioration of collagen-induced arthritis by Salix nigra bark extract via suppression of pro-inflammatory cytokines and oxidative stress.
PubMed:
Antioxidant activity of flavonoids evaluated with myoglobin method.
PubMed:
The antioxidant protection of CELLFOOD against oxidative damage in vitro.
PubMed:
Hydrogen [corrected] peroxide-dependent photocytotoxicity by phloxine B, a xanthene-type food colorant.
PubMed:
Formation of semicarbazide upon hypochlorous acid treatment of nitrogen containing compounds.
PubMed:
Effects of slightly acidic electrolysed drinking water on mice.
PubMed:
Hypochlorous and peracetic acid induced oxidation of dairy proteins.
PubMed:
Inhibitory activities of soluble and bound millet seed phenolics on free radicals and reactive oxygen species.
PubMed:
Hypochlorous acid scavenging activities of thioallyl compounds from garlic.
PubMed:
Microbicidal and cytotoxic effects of functional water in vitro.
PubMed:
Antimicrobial effects of hypochlorite on Escherichia coli in water and selected vegetables.
PubMed:
Effectiveness of low concentration electrolyzed water to inactivate foodborne pathogens under different environmental conditions.
PubMed:
Bioactive phenolics and antioxidant propensity of flavedo extracts of Mauritian citrus fruits: potential prophylactic ingredients for functional foods application.
PubMed:
Modulating effect of flavonoids and their derivatives on sarcoplasmic reticulum Ca2+-ATPase oxidized by hypochloric acid and peroxynitrite.
PubMed:
Mitigation of Alicyclobacillus spp. spores on food contact surfaces with aqueous chlorine dioxide and hypochlorite.
PubMed:
Semicarbazide is non-specific as a marker metabolite to reveal nitrofurazone abuse as it can form under Hofmann conditions.
PubMed:
Protective effect of isorhamnetin 3-O-beta-D-glucopyranoside from Salicornia herbacea against oxidation-induced cell damage.
PubMed:
Hypochlorite treatments are not a significant source of perchlorate exposure in lettuce.
PubMed:
Pieris brassicae inhibits xanthine oxidase.
PubMed:
Hypochlorite-induced oxidation of dairy proteins: impact of pH and oxidant concentration.
PubMed:
Antioxidant activity, ascorbic acid and total phenol of exotic fruits occurring in Brazil.
PubMed:
Targeted metabolite analysis and antioxidant potential of Rumex induratus.
PubMed:
Galloylated catechins as potent inhibitors of hypochlorous acid-induced DNA damage.
PubMed:
Identification and antioxidant activity of melanin isolated from Hypoxylon archeri, a companion fungus of Tremella fuciformis.
PubMed:
New C-deoxyhexosyl flavones and antioxidant properties of Passiflora edulis leaf extract.
PubMed:
Reduction of bacteria on spinach, lettuce, and surfaces in food service areas using neutral electrolyzed oxidizing water.
PubMed:
Locations of hypochlorite oxidation in corn starches varying in amylose content.
PubMed:
New insights into controversies on the antioxidant potential of the olive oil antioxidant hydroxytyrosol.
PubMed:
S-allylcysteine scavenges singlet oxygen and hypochlorous acid and protects LLC-PK(1) cells of potassium dichromate-induced toxicity.
PubMed:
Proteomic analysis of a hypochlorous acid-tolerant Listeria monocytogenes cultural variant exhibiting enhanced biofilm production.
PubMed:
Neutrophil interaction with the hemostatic system contributes to liver injury in rats cotreated with lipopolysaccharide and ranitidine.
PubMed:
Phenolic compounds, organic acids profiles and antioxidative properties of beefsteak fungus (Fistulina hepatica).
PubMed:
Investigation of pathways of advanced glycation end-products accumulation in macrophages.
PubMed:
Comparison of rinsing and sanitizing procedures for reducing bacterial pathogens on fresh cantaloupes and bell peppers.
PubMed:
Reaction pathways of the diketonitrile degradate of isoxaflutole with hypochlorite in water.
PubMed:
Estrogenic activity of the chlorinated derivatives of estrogens and flavonoids using a GFP expression system.
PubMed:
Mechanisms of actions of sodium hypochlorite in cleaning and disinfection processes.
PubMed:
Hypochlorous acid-derived modification of phospholipids: characterization of aminophospholipids as regulatory molecules for lipid peroxidation.
PubMed:
Study on inactivation kinetics of hepatitis A virus and enteroviruses with peracetic acid and chlorine. New ICC/PCR method to assess disinfection effectiveness.
PubMed:
Protective effect of Ugni molinae Turcz against oxidative damage of human erythrocytes.
PubMed:
Characterization of the microbial flora in disinfecting footbaths with hypochlorite.
PubMed:
Structural characteristics and physicochemical properties of oxidized corn starches varying in amylose content.
PubMed:
Antioxidant screening of medicinal herbal teas.
PubMed:
Investigation into the resistance of lactoperoxidase tolerant Escherichia coli mutants to different forms of oxidative stress.
PubMed:
Inactivation of Escherichia coli O157:H7 in biofilm on stainless steel by treatment with an alkaline cleaner and a bacteriophage.
PubMed:
5,5-Dimethyl-2-pyrrolidone-N-oxyl formation in electron spin resonance studies of electrolyzed NaCl solution using 5,5-dimethyl-1-pyrroline-N-oxide as a spin trapping agent.
PubMed:
[Semicarbazide in food].
PubMed:
Antioxidant activity of A-type proanthocyanidins from Geranium niveum (Geraniaceae).
PubMed:
Endogenous formation of novel halogenated 2'-deoxycytidine. Hypohalous acid-mediated DNA modification at the site of inflammation.
PubMed:
Comparison of the inhibition of myeloperoxidase-catalyzed hypochlorite formation in vitro and in whole blood by different plant extracts contained in a phytopharmacon treating functional dyspepsia.
PubMed:
Hypochlorite inactivation kinetics of Listeria monocytogenes in phosphate buffer.
PubMed:
Efficacy of chlorine dioxide gas as a sanitizer of lettuce leaves.
PubMed:
Internalization of bacterial pathogens in tomatoes and their control by selected chemicals.
PubMed:
Hypochlorite scavenging activity of flavonoids.
PubMed:
Renibacterium salmoninarum: effect of hypochlorite treatment, and survival in water.
PubMed:
Formation of semicarbazide (SEM) in food by hypochlorite treatment: is SEM a specific marker for nitrofurazone abuse?
PubMed:
Degradation of isoxaflutole (balance) herbicide by hypochlorite in tap water.
PubMed:
Isolation and identification of terpene chlorohydrins found in cold-pressed orange oil.
PubMed:
Infectivity of RNA from inactivated poliovirus.
PubMed:
Capsid functions of inactivated human picornaviruses and feline calicivirus.
PubMed:
Scavenging property of three cresol isomers against H2O2, hypochlorite, superoxide and hydroxyl radicals.
PubMed:
Development of a standard test to assess the resistance of Staphylococcus aureus biofilm cells to disinfectants.
PubMed:
Antioxidative properties of cardoon (Cynara cardunculus L.) infusion against superoxide radical, hydroxyl radical, and hypochlorous acid.
PubMed:
Mechanisms contributing to hypochlorous acid resistance of a Salmonella isolate from a poultry-processing plant.
PubMed:
Decontamination of aflatoxin-forming fungus and elimination of aflatoxin mutagenicity with electrolyzed NaCl anode solution.
PubMed:
Melatonin in plants.
PubMed:
The physiological role and pharmacological potential of nitric oxide in neutrophil activation.
PubMed:
Biofilm formation by salmonella spp. on food contact surfaces and their sensitivity to sanitizers.
PubMed:
Ultraviolet spectrophotometric characterization and bactericidal properties of electrolyzed oxidizing water as influenced by amperage and pH.
PubMed:
Survival of Yersinia enterocolitica and mesophilic aerobic bacteria on eggshell after washing with hypochlorite and organic acid solutions.
PubMed:
Efficacy of novel organic acid and hypochlorite treatments for eliminating Escherichia coli O157:H7 from alfalfa seeds prior to sprouting.
PubMed:
The effectiveness of hygiene procedures for prevention of cross-contamination from chicken carcases in the domestic kitchen.
PubMed:
Antioxidant and other biological activities of olive mill waste waters.
PubMed:
Effectiveness of various disinfectants in the elimination of Yersinia enterocolitica on fresh lettuce.
PubMed:
Isolation of Salmonella resistant to hypochlorous acid from a poultry abattoir.
PubMed:
Rapid monitoring method to assess efficacy of sanitizers against Pseudomonas putida biofilms.
PubMed:
Acid adaptation sensitizes Salmonella typhimurium to hypochlorous acid.
PubMed:
Nutrition and health aspects of free radicals and antioxidants.
PubMed:
Evaluation of the antioxidant actions of ferulic acid and catechins.
PubMed:
An assessment of cleaning and sampling methods for food-contact surfaces in premises preparing and selling high-risk foods.
PubMed:
In vivo bioluminescence: a cellular reporter for research and industry.
PubMed:
Reactions of aqueous chlorine and chlorine dioxide with model food compounds.
PubMed:
Use of nitrite and hypochlorite treatments in determination of the contributions of IQ-type and non-IQ-type heterocyclic amines to the mutagenicities in crude pyrolyzed materials.
PubMed:
Oxidative inactivation of ethylenethiourea by hypochlorite in alkaline medium.
PubMed:
Methods in coccidiosis research: separation of oocysts from faeces.
PubMed:
The effects of various treatments on the microbial flora of whole poultry carcasses with particular reference to Staphylococcus aureus contamination.