1,3-propanedione, 1-(4-methoxy-5-benzofuranyl)-3-phenyl-

CAS: 484-33-3 C18 H14 O4 MW: 294.30638000

Identification

Namepongamol
CAS Number484-33-3
FDA UNII8Y19QCY6I4
Molecular FormulaC18 H14 O4
Molecular Weight294.30638000
MDL NumberMFCD00017412

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 448.70 °C. @ 760.00 mm Hg (est)
Flash Point 426.00 °F. TCC ( 218.70 °C. ) (est)
logP (o/w) 2.676 (est)
Soluble in water, 47.92 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesfragrance

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorycosmetic agents
Recommendation for pongamol usage levels up tonot for fragrance use.
Recommendation for pongamol flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

found in nature

Synonyms

1-(1- benzofuran-5-yl)-3-phenyl-1,3-propanedione 1-(1- benzofuran-5-yl)-3-phenylpropane-1,3-dione 1-(4- methoxy-5-benzofuranyl)-3-phenyl-1,3-propane dione 1-(4- methoxy-5-benzofuranyl)-3-phenyl-1,3-propanedione 1,3- propanedione, 1-(4-methoxy-5-benzofuranyl)-3-phenyl- PubMed: A new 1,2-ethanedione benzofurane derivative from Tephrosia purpurea. PubMed: Medicinal uses, phytochemistry and pharmacology of Pongamia pinnata (L.) Pierre: a review. PubMed: Revisiting curcumin chemistry part I: a new strategy for the synthesis of curcuminoids. PubMed: Pongamol from Pongamia pinnata stimulates glucose uptake by increasing surface GLUT4 level in skeletal muscle cells. PubMed: New furanoflavanoids, intestinal alpha-glucosidase inhibitory and free-radical (DPPH) scavenging, activity from antihyperglycemic root extract of Derris indica (Lam.). PubMed: Identification of pongamol and karanjin as lead compounds with antihyperglycemic activity from Pongamia pinnata fruits. PubMed: Flavonoids of Lonchocarpus montanus A.M.G. Azevedo and biological activity. PubMed: Activity-guided isolation of constituents of Tephrosia purpurea with the potential to induce the phase II enzyme, quinone reductase.