prunella vulgaris flower/leaf/stem extract

extract of the flowers, leaves and stems of prunella vulgaris l., lamiaceae

CAS: 90105-92-3

Identification

Nameprunella vulgaris flower/leaf/stem extract
CAS Number90105-92-3
FDA UNIISearch

Regulatory

Physical Properties

Food Chemicals Codex Listed No

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesskin protecting agents

No sensory data available

Safety Information

Oral/Parenteral Toxicityintraperitoneal-mouse LD50 750 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorycosmetic ingredient for skin protecting
Recommendation for prunella vulgaris flower/leaf/stem extract usage levels up tonot for fragrance use.
Recommendation for prunella vulgaris flower/leaf/stem extract flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

prunella vulgaris

Synonyms

austakhadus flower/leaf/stem extract extract of the flowers, leaves and stems of prunella vulgaris l., lamiaceae heal all flower/leaf/stem extract heal-all flower/leaf/stem extract self heal flower/leaf/stem extract self-heal flower/leaf/stem extract PubMed: Extracts of endophytic fungus xkc-s03 from Prunella vulgaris L. spica inhibit gastric cancer in vitro and in vivo. PubMed: Pentacyclic triterpenoids from spikes of Prunella vulgaris L. inhibit glycogen phosphorylase and improve insulin sensitivity in 3T3-L1 adipocytes. PubMed: SKI306X inhibition of glycosaminoglycan degradation in human cartilage involves down-regulation of cytokine-induced catabolic genes. PubMed: Anti-diabetic effects of the ethanol extract of a functional formula diet in mice fed with a fructose/fat-rich combination diet. PubMed: In vitro antioxidant and anticancer effects of solvent fractions from Prunella vulgaris var. lilacina. PubMed: Effects of Prunella vulgaris on the mice immune function. PubMed: NF-κB-targeted anti-inflammatory activity of Prunella vulgaris var. lilacina in macrophages RAW 264.7. PubMed: Anti-Proliferative Effect of an Aqueous Extract of Prunella vulgaris in Vascular Smooth Muscle Cells. PubMed: The protective effect of Prunella vulgaris ethanol extract against vascular inflammation in TNF-α-stimulated human aortic smooth muscle cells. PubMed: Prunella vulgaris attenuates prepulse inhibition deficit and attention disruption induced by MK-801 in mice. PubMed: The inhibitory effect of Prunella vulgaris L. on aldose reductase and protein glycation. PubMed: Prunella vulgaris aqueous extract attenuates IL-1β-induced apoptosis and NF-κB activation in INS-1 cells. PubMed: Anti-diabetic atherosclerosis effect of Prunella vulgaris in db/db mice with type 2 diabetes. PubMed: [Experimental study of extract from Prunella vulgaris inducing B, T lymphoma cell apoptosis]. PubMed: The aqueous extract of Prunella vulgaris suppresses cell invasion and migration in human liver cancer cells by attenuating matrix metalloproteinases. PubMed: A new unusual delta11(12)-oleane triterpene and anti-complementary triterpenes from Prunella vulgaris spikes. PubMed: [Analyze on the component of rosmarinic acid in Prunella vulgaris and its effect on alpha-glycosidase activity]. PubMed: Prunella vulgaris suppresses HG-induced vascular inflammation via Nrf2/HO-1/eNOS activation. PubMed: Ethanol extract of Prunella vulgaris var. lilacina inhibits HMGB1 release by induction of heme oxygenase-1 in LPS-activated RAW 264.7 cells and CLP-induced septic mice. PubMed: Permeability of rosmarinic acid in Prunella vulgaris and ursolic acid in Salvia officinalis extracts across Caco-2 cell monolayers. PubMed: [Dynamic change of active component content in different parts of Prunella vulgaris]. PubMed: Evaluation of the anti-neuraminidase activity of the traditional Chinese medicines and determination of the anti-influenza A virus effects of the neuraminidase inhibitory TCMs in vitro and in vivo. PubMed: Oleanolic acid from Prunella Vulgaris L. induces SPC-A-1 cell line apoptosis via regulation of Bax, Bad and Bcl-2 expression. PubMed: Inhibition of HIV-1 infection by aqueous extracts of Prunella vulgaris L. PubMed: Chemoprevention by Prunella vulgaris L. extract of non-small cell lung cancer via promoting apoptosis and regulating the cell cycle. PubMed: Antioxidant activities of total phenols of Prunella vulgaris L. in vitro and in tumor-bearing mice. PubMed: Effect of polyacetylenic acids from Prunella vulgaris on various plant pathogens. PubMed: Identification of two polysaccharides from Prunella vulgaris L. and evaluation on their anti-lung adenocarcinoma activity. PubMed: Prunella vulgaris L. Upregulates eNOS expression in human endothelial cells. PubMed: The ameliorating effect of the extract of the flower of Prunella vulgaris var. lilacina on drug-induced memory impairments in mice. PubMed: Suppression of PMA-induced tumor cell invasion and metastasis by aqueous extract isolated from Prunella vulgaris via the inhibition of NF-kappaB-dependent MMP-9 expression. PubMed: Rosmarinic acid in Prunella vulgaris ethanol extract inhibits lipopolysaccharide-induced prostaglandin E2 and nitric oxide in RAW 264.7 mouse macrophages. PubMed: Prunella vulgaris extract and rosmarinic acid prevent UVB-induced DNA damage and oxidative stress in HaCaT keratinocytes. PubMed: Prunella vulgaris extract and rosmarinic acid suppress lipopolysaccharide-induced alteration in human gingival fibroblasts. PubMed: Inhibition of lentivirus replication by aqueous extracts of Prunella vulgaris. PubMed: Triterpenoic acids of Prunella vulgaris var. lilacina and their cytotoxic activities in vitro. PubMed: Immunostimulatory activity of aqueous extract isolated from Prunella vulgaris. PubMed: Characterization of antiestrogenic activity of the Chinese herb, prunella vulgaris, using in vitro and in vivo (Mouse Xenograft) models. PubMed: Heme oxygenase-1 inducing constituent of Prunella vulgaris in HepG2 cells. PubMed: Effects of Prunella vulgaris on mast cell-mediated allergic reaction and inflammatory cytokine production. PubMed: Antihyperglycemic activity of Prunella vulgaris L. in streptozotocin-induced diabetic mice. PubMed: Photoprotective properties of Prunella vulgaris and rosmarinic acid on human keratinocytes. PubMed: Clematis mandshurica protected to apoptosis of rat chondrocytes. PubMed: In vitro and in vivo immunosuppressive activity of Spica Prunellae ethanol extract on the immune responses in mice. PubMed: Biological activities of Prunella vulgaris extract. PubMed: Inhibitory effects of rosmarinic acid on Lck SH2 domain binding to a synthetic phosphopeptide. PubMed: Effect of SKI 306X, a new herbal anti-arthritic agent, in patients with osteoarthritis of the knee: a double-blind placebo controlled study. PubMed: Inhibition of immediate-type allergic reactions by Prunella vulgaris in a murine model. PubMed: A comparison of HIV-1 integrase inhibition by aqueous and methanol extracts of Chinese medicinal herbs. PubMed: Anti-allergic and anti-inflammatory triterpenes from the herb of Prunella vulgaris. PubMed: Extract of Prunella vulgaris spikes inhibits HIV replication at reverse transcription in vitro and can be absorbed from intestine in vivo. PubMed: Anti-HIV-1 activity of herbs in Labiatae. PubMed: [Screening test of crude drug extract on anti-HIV activity]. PubMed: Mechanism of inhibition of HIV-1 infection in vitro by purified extract of Prunella vulgaris.