carbosulfan

dibutylaminosulfenylcarbofuran

CAS: 55285-14-8 C20 H32 N2 O3 S MW: 380.55164000

Identification

Namecarbosulfan
CAS Number55285-14-8
EINECS259-565-9
FDA UNIIV1DGN4AK6G
Molecular FormulaC20 H32 N2 O3 S
Molecular Weight380.55164000
MDL NumberMFCD00128058
Nikkaji NumberJ1.070G
Beilstein1397995
XlogP35.70 (est)

Regulatory

Physical Properties

Appearance brown viscous liquid (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 462.50 °C. @ 760.00 mm Hg (est)
Flash Point 452.00 °F. TCC ( 233.50 °C. ) (est)
logP (o/w) 6.050 (est)
Soluble in water, 0.3 mg/L @ 25 °C (exp)

No sensory data available

Safety Information

Oral/Parenteral Toxicityoral-bird - wild LD50 26 mg/kg
Dermal Toxicityskin-rabbit LD50 > 2000 mg/kg
Inhalation Toxicityinhalation-rat LC50 1530 mg/m3/1H

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryherbicides / pesticides
Recommendation for carbosulfan usage levels up tonot for fragrance use.
Recommendation for carbosulfan flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

carbamic acid, ((dibutylamino)thio)methyl-, 2,2-dimethyl-2,3-dihydro-7-benzofuranyl ester carbamic acid, ((dibutylamino)thio)methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester carbamic acid, [(dibutylamino)thio]methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester carbamic acid, N-[(dibutylamino)thio]-N-methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester (( dibutylamino)thio)methylcarbamic acid 2,2-dimethyl-2,3-dihydro-7-benzofuranyl ester (( dibutylamino)thio)methylcarbamic acid 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester (( dibutylamino)thio)methylcarbamic acid, 2,2-dimethyl-2,3-dihydro-7-benzofuranyl ester N-[( dibutylamino)thio]-N-methylcarbamic acid 2,3-dihydro-2,2-dimethyl; -7-benzofuranyl ester dibutylaminosulfenylcarbofuran 2,3- dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate 2,3- dihydro-2,2-dimethyl-7-benzofuranyl (di-n-butylaminosulfenyl)methylcarbamate 2,3- dihydro-2,2-dimethyl-7-benzofuranyl[(dibutylamino)thio]methyl carbamate 2,3- dihydro-2,2-dimethyl-7-benzofuryl [(dibutylamino)thio]methylcarbamate 2,2- dimethyl-2,3-dihydro-1-benzofuran-7-yl (dibutylamino)sulfanyl(methyl)carbamate 2,2- dimethyl-2,3-dihydro-1-benzofuran-7-yl [(dibutylamino)sulfanyl](methyl)carbamate 2,2- dimethyl-2,3-dihydro-1-benzofuran-7-yl [(dibutylamino)sulfanyl]methylcarbamate (2,2- dimethyl-3H-1-benzofuran-7-yl) N-(dibutylamino)sulfanyl-N-methylcarbamate marshal 10G (salt/mix) marshal/suscon (salt/mix) marshall 10G (salt/mix) PubMed: The combined toxicity assessment of carp (Cyprinus carpio) acetylcholinesterase activity by binary mixtures of chlorpyrifos and four other insecticides. PubMed: Induction of micronuclei and nuclear lesions in Channa punctatus following exposure to carbosulfan, glyphosate and atrazine. PubMed: Biochemical and molecular characterization and cross-resistance in field and laboratory chlorpyrifos resistant strains of Laodelphax striatellus (Hemiptera: Delphacidae) from eastern China. PubMed: [Rapid screening of 176 pesticide residues in vegetables by ultra fast liquid chromatography-tandem mass spectrometry]. PubMed: Effects of chronic carbosulfan exposure on liver antioxidant enzyme activities in rainbow trout. PubMed: Assessment of potential sublethal effects of various insecticides on key biological traits of the tobacco whitefly, Bemisia tabaci. PubMed: Persistence behavior of imidacloprid and carbosulfan in mango (Mangifera indica L.). PubMed: High-level of resistance to spinosad, emamectin benzoate and carbosulfan in populations of Thrips tabaci collected in Israel. PubMed: Analysis of carbofuran, carbosulfan, isoprocarb, 3-hydroxycarbofuran, and 3-ketocarbofuran by micellar electrokinetic chromatography. PubMed: [Toxicity and bioactivity of several alternative nematocides against Ditylenchus destructor]. PubMed: Acute toxicity of Roundup and carbosulfan to the Thai fairy shrimp, Branchinella thailandensis. PubMed: Simultaneous quantification of carbamate insecticides in human plasma by liquid chromatography/tandem mass spectrometry. PubMed: Development of a new QuEChERS method based on dry ice for the determination of 168 pesticides in paprika using tandem mass spectrometry. PubMed: Influence of bioassay volume, water column height, and octanol-water partition coefficient on the toxicity of pesticides to rainbow trout. PubMed: Fate of carbosulfan and monocrotophos in sandy loam soils of Pakistan under field conditions at different watertable depths. PubMed: [Preliminary evaluation of the insecticide susceptibility in Anopheles gambiae and Culex quinquefasciatus from Lobito (Angola), using WHO standard assay]. PubMed: Insecticide resistance in the Anopheles gambiae complex in Benin: a nationwide survey. PubMed: Effects of some pesticides on the vital organs of juvenile rainbow trout (Oncorhynchus mykiss). PubMed: Distribution of ace-1R and resistance to carbamates and organophosphates in Anopheles gambiae s.s. populations from Côte d'Ivoire. PubMed: Metabolism of carbosulfan II. Human interindividual variability in its in vitro hepatic biotransformation and the identification of the cytochrome P450 isoforms involved. PubMed: Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions. PubMed: Behavioural and insecticidal effects of organophosphate-, carbamate- and pyrethroid-treated mosquito nets against African malaria vectors. PubMed: Cross-resistance study and biochemical mechanisms of thiamethoxam resistance in B-biotype Bemisia tabaci (Hemiptera: Aleyrodidae). PubMed: Use of semipermeable membrane devices for monitoring pesticides in indoor air. PubMed: Insecticide resistance traits differ among and within host races in Aphis gossypii. PubMed: Determination of pesticide residues in integrated pest management and nonintegrated pest management samples of apple (Malus pumila Mill.). PubMed: Mutagenic and genotoxic effects of carbosulfan in freshwater fish Channa punctatus (Bloch) using micronucleus assay and alkaline single-cell gel electrophoresis. PubMed: Virulence development and genetic polymorphism in Meloidogyne incognita (Kofoid & White) Chitwood after prolonged exposure to sublethal concentrations of nematicides and continuous growing of resistant tomato cultivars. PubMed: Metabolism of carbosulfan. I. Species differences in the in vitro biotransformation by mammalian hepatic microsomes including human. PubMed: Impact of some selected insecticides application on soil microbial respiration. PubMed: Purification and partial characterization of glutathione S-transferase from insecticide-resistant field populations of Liposcelis paeta Pearman (Psocoptera: Liposcelididae). PubMed: Multivariate analysis of toxicological and environmental properties of soil nematicides. PubMed: Effects of carbosulfan administration schedules on estrous cycle and follicular dynamics in albino mice. PubMed: Comparison of hollow fiber liquid phase microextraction and dispersive liquid-liquid microextraction for the determination of organosulfur pesticides in environmental and beverage samples by gas chromatography with flame photometric detection. PubMed: Abamectin, pymetrozine and azadirachtin sequence as a unique solution to control the leafminer Liriomyza trifolii (Burgess) (Diptera: Agromyzidae) infesting garden beans (Phaseolus vulgaris L.) in Egypt. PubMed: An approach for IPM program to control sucking pests infesting garden bean plants (Phaseolus vulgaris L.) in Egypt. PubMed: Influence of organic matter on bio-availability of carbosulfan and its toxicity on a carabid beetle. PubMed: Relationship between desert locust, Schistocerca gregaria (Forskål), infestation, environmental factors and control measures in Gazan and Makkah Regions, Saudi Arabia. PubMed: Characterization of insensitive acetylcholinesterase (ace-1R) in Anopheles gambiae (Diptera: Culicidae): resistance levels and dominance. PubMed: [Behavior of N-methylcarbamate pesticides during refinement processing of edible oils]. PubMed: Effects of biological and technical factors on brain and muscle cholinesterases in Nile tilapia, Oreochromis niloticus: implications for biomonitoring neurotoxic contaminations. PubMed: Optimization of LC-MS/MS using triple quadrupole mass analyzer for the simultaneous analysis of carbosulfan and its main metabolites in oranges. PubMed: Effect of application of different pesticides to soybean on the soil microflora. PubMed: [Fitness cost associated with carbosulfan resistance in Aphis gossypii Glover (Hemiptera: Aphididae)]. PubMed: Liquid chromatography quadrupole time-of-flight mass spectrometry analysis of carbosulfan, carbofuran, 3-hydroxycarbofuran, and other metabolites in food. PubMed: Synergism studies with binary mixtures of pyrethroid, carbamate and organophosphate insecticides on Frankliniella occidentalis (Pergande). PubMed: Facile and sensitive spectrophotometric determination of carbosulfan in formulations and environmental samples. PubMed: Comparison of four mass analyzers for determining carbosulfan and its metabolites in citrus by liquid chromatography/mass spectrometry. PubMed: Body size-related differences in the inhibition of brain acetylcholinesterase activity in juvenile Nile tilapia (Oreochromis niloticus) by chlorpyrifos and carbosulfan. PubMed: Differential responses of eight cyanobacterial and green algal species, to carbamate insecticides. PubMed: Transformation and ecotoxicity of carbamic pesticides in water. PubMed: Determination of carbosulfan and its metabolites in oranges by liquid chromatography ion-trap triple-stage mass spectrometry. PubMed: Inhibitory effects of four carbamate insecticides on acetylcholinesterase of male and female Carassius auratus in vitro. PubMed: Response of brain and liver cholinesterases of Nile tilapia, Oreochromis niloticus, to single and multiple exposures of chlorpyrifos and carbosulfan. PubMed: Selectivity of pesticides used on cotton (Gossypium hirsutum) to Trichogramma pretiosum reared on two laboratory-reared hosts. PubMed: Degradation and persistence of cotton pesticides in sandy loam soils from Punjab, Pakistan. PubMed: Kinetics of carbosulfan hydrolysis to carbofuran and the subsequent degradation of this last compound in irrigated rice fields. PubMed: Pesticide pollution remains severe after cleanup of a stockpile of obsolete pesticides at Vikuge, Tanzania. PubMed: Forearm compartment syndrome after intravenous mannitol extravasation in a carbosulfan poisoning patient. PubMed: Liquid chromatography-electrospray quadrupole ion-trap mass spectrometry of nine pesticides in fruits. PubMed: Pressurized hot water extraction of insecticides from process dust--comparison with supercritical fluid extraction. PubMed: Dinotefuran: a potential neonicotinoid insecticide against resistant mosquitoes. PubMed: Experimental hut comparisons of nets treated with carbamate or pyrethroid insecticides, washed or unwashed, against pyrethroid-resistant mosquitoes. PubMed: Efficacy of mosquito nets treated with insecticide mixtures or mosaics against insecticide resistant Anopheles gambiae and Culex quinquefasciatus (Diptera: Culicidae) in Côte d'Ivoire. PubMed: Development of a simultaneous analysis method for carbofuran and its three derivative pesticides in water by GC/MS with temperature programmable inlet on-column injection. PubMed: Comparative evaluation of carbosulfan- and permethrin-impregnated curtains for preventing house-entry by the malaria vector Anopheles gambiae in Burkina Faso. PubMed: Insecticide resistance in Egyptian populations of the cotton whitefly, Bemisia tabaci (Hemiptera: Aleyrodidae). PubMed: In vitro dermal penetration study of carbofuran, carbosulfan, and furathiocarb. PubMed: Resistance to carbosulfan in Anopheles gambiae from Ivory Coast, based on reduced sensitivity of acetylcholinesterase. PubMed: Multiple dose-activated charcoal as a cause of acute appendicitis. PubMed: Induction of sister chromatid exchanges by cypermethrin and carbosulfan in bone marrow cells of mice in vivo. PubMed: Insecticide mixtures for mosquito net impregnation against malaria vectors. PubMed: Mutagenic effects of carbosulfan, a carbamate pesticide. PubMed: Influence of clay minerals on the hydrolysis of carbamate pesticides. PubMed: Combined pyrethroid and carbamate 'two-in-one' treated mosquito nets: field efficacy against pyrethroid-resistant Anopheles gambiae and Culex quinquefasciatus. PubMed: Risk assessment of etofenprox (Vectron) on non-target aquatic fauna compared with other pesticides used as Simulium larvicide in a tropical environment. PubMed: Supercritical fluid extraction of the pesticides carbosulfan and imidacloprid from process dust waste. PubMed: Experimental and molecular genetic analysis of the impact of pyrethroid and non-pyrethroid insecticide impregnated bednets for mosquito control in an area of pyrethroid resistance. PubMed: The kdr pyrethroid resistance gene in Anopheles gambiae: tests of non-pyrethroid insecticides and a new detection method for the gene. PubMed: Microbial degradation of carbosulfan by carbosulfan--and carbofuran-retreated rice soil suspension. PubMed: Distribution of organophosphate and carbamate resistance in Culex pipiens quinquefasciatus (Diptera: Culicidae) in West Africa. PubMed: In vivo chromosomal aberrations in bone marrow cells of rats treated with Marshal. PubMed: Genotoxic evaluation of three heterocyclic N-methylcarbamate pesticides using the mouse bone marrow micronucleus assay and the Saccharomyces cerevisiae strains D7 and D61.M. PubMed: Determination of carbosulfan in oranges by high-performance liquid chromatography with post-column fluorescence. PubMed: Effects of benzofuran and seven benzofuran derivatives including four carbamate insecticides in the in vitro porcine brain tubulin assembly assay and description of a new approach for the evaluation of the test data. PubMed: Short-term effects of carbosulfan on drifting invertebrates in the Black Volta, Ghana. PubMed: Chromosomal aberrations in cultured human lymphocytes treated with Marshal and its effective ingredient Carbosulfan. PubMed: Effect of moisture regime, temperature, and organic matter on soil persistence of carbosulfan. PubMed: Laboratory toxicity of potential blackfly larvicides on some African fish species in the Onchocerciasis Control Programme area. PubMed: A simple spectrophotometric method for determination of carbosulfan and propoxur. PubMed: Persistence of carbamate insecticides, carbosulfan and carbofuran in soils as influenced by temperature and microbial activity. PubMed: Insecticidal activity of carbosulfan (OMS 3022) and pyraclofos (OMS 3040) against mosquitoes. PubMed: Maintenance of effective control of Simulium damnosum in the face of insecticide resistance. PubMed: Management of insecticide resistance in control of the Simulium damnosum complex by the Onchocerciasis Control Programme, West Africa: potential use of negative correlation between organophosphate resistance and pyrethroid susceptibility. PubMed: Sublethal acute toxicity of carbosulfan [2,3-dihydro-2,2-dimethyl-7-benzofuranyl(d i-n-butylaminosulfenyl)(methyl)carbamate] in the rat after intravenous and oral exposures. PubMed: Leaf, fruit, and soil surface residues of carbosulfan and its metabolites in Florida citrus groves. PubMed: Metabolism of carbosulfan in Valencia orange tree leaves and fruit. PubMed: Worker reentry research for carbosulfan applied to California citrus trees. PubMed: Determination of carbosulfan and carbofuran residues in plants, soil, and water by gas chromatography. PubMed: Alteration of carbosulfan [2,3-dihydro-2,2-dimethyl-7-benzofuranyl (Di-n-butylaminosulfenyl)methylcarbamate] in the rat stomach.