angelica gigas extract

chao xian dang gui extract extract of the plant, angelica gigas, apiaceae oni-nodake extract PubMed: Effect of nodakenin on atopic dermatitis-like skin lesions. PubMed: Decursin attenuates kainic acid-induced seizures in mice. PubMed: Immunomodulatory and Antidiabetic Effects of a New Herbal Preparation (HemoHIM) on Streptozotocin-Induced Diabetic Mice. PubMed: An ethanolic extract of Angelica gigas improves atherosclerosis by inhibiting vascular smooth muscle cell proliferation. PubMed: Herbal extract SH003 suppresses tumor growth and metastasis of MDA-MB-231 breast cancer cells by inhibiting STAT3-IL-6 signaling. PubMed: Development of a pharmacokinetic/pharmacodynamic/disease progression model in NC/Nga mice for development of novel anti-atopic dermatitis drugs. PubMed: Anti-inflammatory and anti-proliferative effect of herbal medicines (APR) in RAW264.7 cells. PubMed: Decursin prevents TPA-induced invasion through suppression of PKCα/p38/NF-κB-dependent MMP-9 expression in MCF-7 human breast carcinoma cells. PubMed: Two novel Talaromyces species isolated from medicinal crops in Korea. PubMed: Preventative effect of an herbal preparation (HemoHIM) on development of airway inflammation in mice via modulation of Th1/2 cells differentiation. PubMed: A New Herbal Formula, KSG-002, Suppresses Breast Cancer Growth and Metastasis by Targeting NF- κ B-Dependent TNF α Production in Macrophages. PubMed: Decursin and Doxorubicin Are in Synergy for the Induction of Apoptosis via STAT3 and/or mTOR Pathways in Human Multiple Myeloma Cells. PubMed: Decursin Isolated from Angelica gigas Nakai Rescues PC12 Cells from Amyloid β-Protein-Induced Neurotoxicity through Nrf2-Mediated Upregulation of Heme Oxygenase-1: Potential Roles of MAPK. PubMed: Decursin exerts anti-cancer activity in MDA-MB-231 breast cancer cells via inhibition of the Pin1 activity and enhancement of the Pin1/p53 association. PubMed: Single oral dose pharmacokinetics of decursin, decursinol angelate, and decursinol in rats. PubMed: A (S)-(+)-decursin derivative, (S)-(+)-3-(3,4-dihydroxy-phenyl)-acrylic acid 2,2-dimethyl-8-oxo-3,4-dihydro-2H,8H-pyrano[3,2-g]-chromen-3-yl-ester, attenuates the development of atopic dermatitis-like lesions in NC/Nga mice. PubMed: New discrimination method combining hit quality index based spectral matching and voting. PubMed: Decursin inhibits UVB-induced MMP expression in human dermal fibroblasts via regulation of nuclear factor-κB. PubMed: Ultrafine Angelica gigas powder normalizes ovarian hormone levels and has antiosteoporosis properties in ovariectomized rats: particle size effect. PubMed: Biopharmaceutical characterization of decursin and their derivatives for drug discovery. PubMed: The memory ameliorating effects of INM-176, an ethanolic extract of Angelica gigas, against scopolamine- or Aβ(1-42)-induced cognitive dysfunction in mice. PubMed: Protective effects of a novel synthetic α-lipoic acid-decursinol hybrid compound in experimentally induced transient cerebral ischemia. PubMed: Physicochemical characterization and toxicity of decursin and their derivatives from Angelica gigas. PubMed: Anti-cancer and other bioactivities of Korean Angelica gigas Nakai (AGN) and its major pyranocoumarin compounds. PubMed: First-pass metabolism of decursin, a bioactive compound of Angelica gigas, in rats. PubMed: Food- and gender-dependent pharmacokinetics of paeoniflorin after oral administration with Samul-tang in rats. PubMed: Neuroprotective effects of INM-176 against lipopolysaccharide-induced neuronal injury. PubMed: Decursin inhibits vasculogenesis in early tumor progression by suppression of endothelial progenitor cell differentiation and function. PubMed: Chemometric classification of morphologically similar Umbelliferae medicinal herbs by DART-TOF-MS fingerprint. PubMed: Quantitative determination of decursin, decursinol angelate, and decursinol in mouse plasma and tumor tissue using liquid-liquid extraction and HPLC. PubMed: Decursin, an active compound isolated from Angelica gigas, inhibits fat accumulation, reduces adipocytokine secretion and improves glucose tolerance in mice fed a high-fat diet. PubMed: The effect of herbal extract (EstroG-100) on pre-, peri- and post-menopausal women: a randomized double-blind, placebo-controlled study. PubMed: A synthetic decursin analog with increased in vivo stability suppresses androgen receptor signaling in vitro and in vivo. PubMed: Anti-allergic effects and mechanisms of action of the ethanolic extract of Angelica gigas in dinitrofluorobenzene-induced inflammation models. PubMed: Metabolite profiling of Angelica gigas from different geographical origins using 1H NMR and UPLC-MS analyses. PubMed: Pharmacokinetic characterization of decursinol derived from Angelica gigas Nakai in rats. PubMed: Overexpression of cinnamate 4-hydroxylase gene enhances biosynthesis of decursinol angelate in Angelica gigas hairy roots. PubMed: Immunotoxicity activity from various essential oils of Angelica genus from South Korea against Aedes aegypti L. PubMed: Antiplasmodial and cytotoxic activity of coumarin derivatives from dried roots of Angelica gigas Nakai in vitro. PubMed: Protective effects of decursin and decursinol angelate against amyloid β-protein-induced oxidative stress in the PC12 cell line: the role of Nrf2 and antioxidant enzymes. PubMed: Decursin and decursinol from Angelica gigas inhibit the lung metastasis of murine colon carcinoma. PubMed: Enhancement of pheochromocytoma nerve cell growth by consecutive fractionization of Angelica gigas Nakai extracts. PubMed: Cloning and characterization of phenylalanine ammonia-lyase and cinnamate 4-hydroxylase and pyranocoumarin biosynthesis in Angelica gigas. PubMed: Decursin prevents cisplatin-induced apoptosis via the enhancement of antioxidant enzymes in human renal epithelial cells. PubMed: A modified preparation (LMK03) of the oriental medicine Jangwonhwan reduces Abeta(1-42) level in the brain of Tg-APPswe/PS1dE9 mouse model of Alzheimer disease. PubMed: A modified preparation (LMK03) of the oriental medicine Jangwonhwan reduces Abeta(1-42) level in the brain of Tg-APPswe/PS1dE9 mouse model of Alzheimer disease. PubMed: Synergistic vasorelaxant and antihypertensive effects of Ligusticum wallichii and Angelica gigas. PubMed: Decursinol angelate blocks transmigration and inflammatory activation of cancer cells through inhibition of PI3K, ERK and NF-kappaB activation. PubMed: Decursin inhibits growth of human bladder and colon cancer cells via apoptosis, G1-phase cell cycle arrest and extracellular signal-regulated kinase activation. PubMed: Ethanol extract of Angelica gigas inhibits croton oil-induced inflammation by suppressing the cyclooxygenase - prostaglandin pathway. PubMed: Biotransformation of plant secondary metabolite decursin by Mycobacterium sp. PYR1001. PubMed: Absorption, distribution, metabolism, and excretion of decursin and decursinol angelate from Angelica gigas Nakai. PubMed: Antiproliferative activity of Korean wild vegetables on different human tumor cell lines. PubMed: Evaluation of the phototoxic potential of plants used in oriental medicine. PubMed: Anti-inflammatory effects of an ethanol extract of Angelica gigas in a Carrageenan-air pouch inflammation model. PubMed: The analgesic effect of decursinol. PubMed: ESP-102, a combined extract of Angelica gigas, Saururus chinensis and Schizandra chinensis, protects against glutamate-induced toxicity in primary cultures of rat cortical cells. PubMed: Decursin and decursinol inhibit VEGF-induced angiogenesis by blocking the activation of extracellular signal-regulated kinase and c-Jun N-terminal kinase. PubMed: Decursin and decursinol angelate inhibit VEGF-induced angiogenesis via suppression of the VEGFR-2-signaling pathway. PubMed: In vivo anti-cancer activity of Korean Angelica gigas and its major pyranocoumarin decursin. PubMed: Antidiabetic activity of angelan isolated from Angelica gigas Nakai. PubMed: In vitro inhibitory potential of decursin and decursinol angelate on the catalytic activity of cytochrome P-450 1A1/2, 2D15, and 3A12 isoforms in canine hepatic microsomes. PubMed: Identification of proteins binding to decursinol by chemical proteomics. PubMed: Inhibitory effects of Angelicae Gigantis Radix on osteoclast formation. PubMed: Antioxidant activity and cytotoxicity of methanol extracts from aerial parts of Korean salad plants. PubMed: Neuroprotective coumarins from the root of Angelica gigas: structure-activity relationships. PubMed: Simultaneous determination of eight coumarins in Angelica gigas and in various other Angelica species by high performance liquid chromatography and comparative micro-morphology study of Angelica species. PubMed: The simultaneous determination of coumarins in Angelica gigas root by high performance liquid chromatography-diode array detector coupled with electrospray ionization/mass spectrometry. PubMed: Decursin and decursinol angelate selectively inhibit NADH-fumarate reductase of Ascaris suum. PubMed: Effect of Angelica gigas extract on melanogenesis in B16 melanoma cells. PubMed: Decursin suppresses human androgen-independent PC3 prostate cancer cell proliferation by promoting the degradation of beta-catenin. PubMed: Oriental herbs as a source of novel anti-androgen and prostate cancer chemopreventive agents. PubMed: Decursinol and decursin protect primary cultured rat cortical cells from glutamate-induced neurotoxicity. PubMed: Mechanism-based inactivation of cytochrome P450 2A6 by decursinol angelate isolated from Angelica Gigas. PubMed: Development of gas chromatographic/mass spectrometry-pattern recognition method for the quality control of Korean Angelica. PubMed: Optimized conditions for the extraction of secondary volatile metabolites in Angelica roots by accelerated solvent extraction. PubMed: Nodakenin, a coumarin compound, ameliorates scopolamine-induced memory disruption in mice. PubMed: Transport of decursin and decursinol angelate across Caco-2 and MDR-MDCK cell monolayers: in vitro models for intestinal and blood-brain barrier permeability. PubMed: Volatile organic compounds of Angelica gigas Nakai, Korean medicinal herb. PubMed: A novel class of pyranocoumarin anti-androgen receptor signaling compounds. PubMed: Angelan isolated from Angelica gigas Nakai induces dendritic cell maturation through toll-like receptor 4. PubMed: Identification of volatile components in Angelica species using supercritical-CO2 fluid extraction and solid phase microextraction coupled to gas chromatography-mass spectrometry. PubMed: Determination of volatile flavor components in danggui cultivars by solvent free injection and hydrodistillation followed by gas chromatographic-mass spectrometric analysis. PubMed: Pectic polysaccharide isolated from Angelica gigas Nakai inhibits melanoma cell metastasis and growth by directly preventing cell adhesion and activating host immune functions. PubMed: Potent antiandrogen and androgen receptor activities of an Angelica gigas-containing herbal formulation: identification of decursin as a novel and active compound with implications for prevention and treatment of prostate cancer. PubMed: The essential oil from Angelica gigas NAKAI suppresses nicotine sensitization. PubMed: New anti-inflammatory formulation containing Synurus deltoides extract. PubMed: Decursin and PDBu: two PKC activators distinctively acting in the megakaryocytic differentiation of K562 human erythroleukemia cells. PubMed: Involvement of PKC and ROS in the cytotoxic mechanism of anti-leukemic decursin and its derivatives and their structure-activity relationship in human K562 erythroleukemia and U937 myeloleukemia cells. PubMed: A novel anticancer agent, decursin, induces G1 arrest and apoptosis in human prostate carcinoma cells. PubMed: ESP-102, a standardized combined extract of Angelica gigas, Saururus chinensis and Schizandra chinensis, significantly improved scopolamine-induced memory impairment in mice. PubMed: Four new neuroprotective dihydropyranocoumarins from Angelica gigas. PubMed: Quantification of ligustilides in the roots of Angelica sinensis and related umbelliferous medicinal plants by high-performance liquid chromatography and liquid chromatography-mass spectrometry. PubMed: Protection against beta-amyloid peptide-induced memory impairment with long-term administration of extract of Angelica gigas or decursinol in mice. PubMed: Anti-tumor activities of decursinol angelate and decursin from Angelica gigas. PubMed: Antinociceptive profiles of crude extract from roots of Angelica gigas NAKAI in various pain models. PubMed: Antibacterial coumarins from Angelica gigas roots. PubMed: Decursin from Angelica gigas mitigates amnesia induced by scopolamine in mice. PubMed: Experimental evidences and signal transduction pathways involved in the activation of NF-kappa B/Rel by angelan in murine macrophages. PubMed: Coumarins isolated from Angelica gigas inhibit acetylcholinesterase: structure-activity relationships. PubMed: Activation of mitogen-activated protein kinase pathways by angelan in murine macrophages. PubMed: Differential activation of murine macrophages by angelan and LPS. PubMed: Polyacetylenes from angelica gigas and their inhibitory activity on nitric oxide synthesis in activated macrophages. PubMed: Activation of NF-kappaB/Rel in angelan-stimulated macrophages. PubMed: Characteristic immunostimulation by angelan isolated from Angelica gigas Nakai. PubMed: Decursinol angelate: a cytotoxic and protein kinase C activating agent from the root of Angelica gigas. PubMed: Decursin: a cytotoxic agent and protein kinase C activator from the root of Angelica gigas. PubMed: Coumarins from the root of Angelica gigas Nakai.