dextro,laevo-valine

DL-valine

CAS: 516-06-3 C5 H11 N O2 MW: 117.14807000

Identification

Namedextro,laevo-valine
IUPAC2-amino-3-methylbutanoic acid
CAS Number516-06-3
EINECS208-220-0
FDA UNII4CA13A832H
Molecular FormulaC5 H11 N O2
Molecular Weight117.14807000
MDL NumberMFCD00004267
Nikkaji NumberJ1.282C
Beilstein0506689
CoE Number17023
XlogP3-2.30 (est)

Regulatory

JECFA Food Flavoring1426 DL-valine
DG SANTE Food Flavourings17.023 DL-valine
FEMA Number3444
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)516-06-3 ; DL-VALINE

Physical Properties

Appearance white crystalline powder (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 156.00 to 158.00 °C. @ 760.00 mm Hg
Boiling Point 213.00 to 214.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure 0.000000 mmHg @ 25.00 °C. (est)
Flash Point 412.00 °F. TCC ( 211.20 °C. ) (est)
logP (o/w) -0.268 (est)
Soluble in water, 184 parts in water at 24C

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesantistatic agents

Organoleptic Properties

Odor Strength none
Odor Description at 100.00 %.

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryspecial dietary and nutritional additives
Recommendation for dextro,laevo-valine usage levels up tonot for fragrance use.
Maximised Survey-derived Daily Intakes (MSDI-EU)35.00 (μg/capita/day)
baked goods-
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum-
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

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Potential Uses

antistatic agents

Natural Occurrence

animal tissues PMC dairy products PMC fruits PMC milk PMC

Synonyms

a- amino-2,3-dihydro-5-methyl-3-oxoisoxazolepropionic acid 2- amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)-propionic acid 2- amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propionic acid (R,S)-2- amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic acid 2- amino-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic acid 2- amino-3-(5-methyl-3-oxo-2,3-dihydro-1,2-oxazol-4-yl)propanoic acid 2- amino-3-(5-methyl-3-oxo(2-hydroisoxazol-4-yl))propanoic acid (RS)-a- amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid a- amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid DL-a- amino-3-hydroxy-5-methylisoxazole-4-propionic acid dextro,laevo-2- amino-3-methyl butanoic acid dextro,laevo-2- amino-3-methyl butyric acid 2- amino-3-methylbutanoic acid DL-2- amino-3-methylbutanoic acid DL-2- amino-3-methylbutyric acid DL-alpha- aminoisovaleric acid dextro,laevo-alpha- aminoisovaleric acid 2- ammonio-3-(3-hydroxy-5-methyl-1,2-oxazol-4-yl)propanoate (R,S)- AMPA (RS)- AMPA AMPA (RS)- 3-(3- hydroxy-5-methyl-1,2-oxazol-4-yl)alanine 3-(5- methyl-3-oxo-2,3-dihydro-1,2-oxazol-4-yl)alanine DL-2-iso propyl glycine dextro,laevo-2-iso propyl glycine DL- valine 4-iso xazolepropanoic acid, a-amino-2,3-dihydro-5-methyl-3-oxo- 4-iso xazolepropanoic acid, a-amino-3-hydroxy-5-methyl- PubMed: Intermolecular vibrations in hydrophobic amino acid crystals: experiments and calculations. PubMed: Development of a pilot-scale manufacturing process for protein-coated microcrystals (PCMC): mixing and precipitation - part I. PubMed: Dipolar origin of water etching of amino acid surfaces. PubMed: 2₄-SEMA as a sensitive and offset compensated SLF sequence. PubMed: Polynuclear manganese amino acid complexes. PubMed: The first amino acid manganese cluster: a [Mn(IV)2Mn(III)3] DL-valine cage. PubMed: Non-ionic surfactant modified ligand exchange chromatography using copper (II) complex of N,N-dimethyl-L-phenylalanine as the chiral additive for enantioselective amino acids separation. PubMed: Effect of amino acids on tannase biosynthesis by Bacillus licheniformis KBR6. PubMed: Inner-sphere oxidation of ternary iminodiacetatochromium(III) complexes involving DL-valine and L-arginine as secondary ligands. Isokinetic relationship for the oxidation of ternary iminodiacetato-chromium(III) complexes by periodate. PubMed: Oligopeptides and copeptides of homochiral sequence, via beta-sheets, from mixtures of racemic alpha-amino acids, in a one-pot reaction in water; relevance to biochirogenesis. PubMed: Formulation of the adenylate cyclase toxin of Bordetella pertussis as protein-coated microcrystals. PubMed: Partial molar volumes of some alpha-amino acids in aqueous sodium acetate solutions at 308.15 K. PubMed: Vibrational spectral analysis of DL-valine DL-valinium and DL-methionine DL-methioninium picrates. PubMed: Spontaneous resolution of binary copper(II) complexes with racemic dipeptides: crystal structures of glycyl-L-alpha-amino-n-butyrato copper(II) monohydrate, glycyl-D-valinato copper(II) hemihydrate, and glycyl-L-valinato copper(II) hemihydrate. PubMed: Biosynthetic studies on a myxobacterial antibiotic, cystothiazole A: biosynthetic precursors of the carbon skeleton. PubMed: Viscosity behavior of some alpha-amino acids and their groups in water-sodium acetate mixtures. PubMed: Effect of amino acids and vitamins on laccase production by the bird's nest fungus Cyathus bulleri. PubMed: Novel stachyflin derivatives from Stachybotrys sp. RF-7260. Fermentation, isolation, structure elucidation and biological activities. PubMed: The stability constants of copper(II) complexes with some alpha-amino acids in dioxan-water mixtures. PubMed: Effect of temperature on viscosity properties of some alpha-amino acids in aqueous urea solutions. PubMed: One- and two-dimensional 13C-1H/15N- 1H dipolar correlation experiments under fast magic-angle spinning for determining the peptide dihedral angle phi. PubMed: Direct thin layer chromatography enantioresolution of some basic DL-amino acids using a pharmaceutical industry waste as chiral impregnating reagent. PubMed: Studies on the protonation constants and solvation of alpha-amino acids in dioxan-water mixtures. PubMed: Hydroxyl radical-induced hydrogen/deuterium exchange in amino acid carbon-hydrogen bonds. PubMed: [Thermodynamic and spectroscopic study of complex formation of dipeptides with dimethyl sulfoxide in their aqueous solutions]. PubMed: [The neurotropic and cardiotropic properties of new amino acid derivatives of isonicotinic acid]. PubMed: Mössbauer effect studies on some bioinorganic complexes of europium. PubMed: Studies on asymmetric induction associated with the coupling of N-acylamino acids and N-benzyloxycarbonyldipeptides. PubMed: Biochemical and ultrastructural studies induced by phanquone on Entamoeba histolytica NIH-200. PubMed: Sensitivity of protein and RNA synthesis to antiamoebic drugs in axenic Entamoeba histolytica (NIH-200). PubMed: [Studies on the stability of complexes of Cu(II), Ni(II), Zn(II) and Co(II) with DL-alanine and DL-valine]. PubMed: Sensitivity of protein and RNA synthesis to emetine in axenic Entamoeba histolytica. PubMed: Thermal properties of water in myoglobin crystals and solutions at subzero temperatures. PubMed: Models of molecular evolution. 2. Stereospecificity of dipeptide syntheses by means of cyanamides and carbodiimides. PubMed: Milbemycins, a new family of macrolide antibiotics. Studies on the biosynthesis of milbemycins alpha 2, alpha 4 and D using 13C labeled precursors. PubMed: Incorporation of 3H-2,3-DL-valine into pancreatic proteins of adrenalectomized rats stimulated with pancreozymin-CCK and secretin. PubMed: Antitumor and antiinflammatory agents: N-benzoyl-protected cyanomethyl esters of amino acids. PubMed: Carbon-11-labeled amino acids for the rectilinear and positron tomographic imaging of the human pancreas. PubMed: [Alkylating derivatives of 2-amino-2-desoxy-1,3,4,6-tetraacetyl-D-glucopyranose (synthesis and experimental study)]. PubMed: Synthesis and biological activity of tuftsin and of [O = C Thr1]-tuftsin. A novel synthetic route to peptides containing N-terminal L -O = C Thr and L - O = C Ser residues. PubMed: Mapping of the locus involved in the catabolic oxidation of D-amino acids in Pseudomonas aeruginosa PAO. PubMed: Anti-inflammatory activity of DL-valine. PubMed: Influence of pregnancy and postpartum period in vitro incorporation of dl-valine-1-14C into oviducal and uterine protein. PubMed: Free radicals produced by gamma irradiation in a single crystal of N-acetyl-DL-valine at 77 K and after heat treatment. PubMed: [1-11C] DL-valine, a potential pancreas-imaging agent. PubMed: Production and chemical studies of protease from Bacillus subtilis (SH-6) Egyptian strain. PubMed: [Study of 14 denitrifying soil bacteria of the "pseudomonas stutzeri" group isolated by enrichment culture in the presence of nitrous oxide (author's transl)]. PubMed: Effect of different concentrations of dl-isoleucine, dl-valine, and dl-alanine on growth and sporulation in Fusarium oxysporum f. udum (Butl.) Sn. et H. PubMed: Paramagnetic centres formed by photolysis in a single crystal of N-acetyl-DL-valine at room temperature. PubMed: Conformation of poly(DL-valine) obtained by the polymerization of the N-carboxy anhydride. PubMed: Influence of amino acids on the growth of Bacteroides melaninogenicus. PubMed: Leucine imbalance in corn-soybean meal diets for laying hens. PubMed: Incorporation of double-labeled L-cystine and DL-valine in penicillin. PubMed: Vitamin B12 nutrition and metabolism in the baboon (Papio cynocephalus). PubMed: Electron-spin resonance of an X-irradiated single crystal of N-acetyl-DL-valine. PubMed: Detection of a cephalosporin C acetyl esterase in the carbamate cephalosporin antibiotic-producing culture, Streptomyces clavuligerus. PubMed: Studies on physiology and biochemistry of the fallopian tube: in vitro uptake of dl-valine-1-C 14 by different parts of the rabbit Fallopian tube during early pregnancy. PubMed: In vivo incorporation of 3 H-2,3-DL-valine in cholate-induced acute pancreatitis in rats. PubMed: [Effect of DL-methionine and DL-valine on elaboration and extinction of a conditioned avoidance reaction (avoidance conditioning)]. PubMed: Biochemical characterization of a mutant isoleucyl-transfer ribonucleic acid synthetase from Escherichia coli K-12. PubMed: [Reaction kinetics of radiation-induced free radicals of glycyl-DL-valine and DL-valyl-glycine during heat treatment and UV-irradiation]. PubMed: [Electron spin resonance spectroscopy of some radiation-induced free radicals of DL-valine, N-acetyl-DL-valine and glycyl-DL-valine]. PubMed: Effect of a contraceptive suture on incorporation of dl-valine-1-14C in the uterine fluid protein of rats. PubMed: [Studies on the dependency upon radiation dose of microwaves saturation in electron spin resonance radiation-induced free radicals of DL-valine and DL-leucine]. PubMed: Alteration of the microwave saturation behaviour after heat treatment in electron spin resonance studies of free radicals produced in DL-valine by x-irradiation. PubMed: Oxidation of D-amino acids by a particulate enzyme from Pseudomonas aeruginosa. PubMed: Gluconeogenesis in the kidney and liver slices of a lizard, Uromastix hardwickii. PubMed: Amino Acid and vitamin requirements of several bacteroides strains. PubMed: Alanine and aspartate formation during growth on valine-C14 by Pseudomonas aeruginosa. PubMed: Oxidation of D- and L-valine by enzymes of Pseudomonas aeruginosa. PubMed: UPTAKE OF VALINE AND GLYCYLVALINE BY LEUCONOSTOC MESENTEROIDES. PubMed: Amino acids as gustatory stimuli in the rat. PubMed: Physiological studies of the rumen protozoan Ophryoscolex caudatus Eberlein. PubMed: [Toxic effects of DL-valine]. PubMed: Biosynthesis of penicillins; utilization of deuterophenylacetyl-N15-dl-valine in penicillin biosynthesis. PubMed: PLASMA PROTEIN PRODUCTION INFLUENCED BY AMINO ACID MIXTURES AND LACK OF ESSENTIAL AMINO ACIDS : A DEFICIENCY STATE RELATED TO UNKNOWN FACTORS. PubMed: TOLERANCE TO AMINO ACID MIXTURES AND CASEIN DIGESTS GIVEN INTRAVENOUSLY : GLUTAMIC ACID RESPONSIBLE FOR REACTIONS. PubMed: AMINO ACID MIXTURES EFFECTIVE PARENTERALLY FOR LONG CONTINUED PLASMA PROTEIN PRODUCTION. CASEIN DIGESTS COMPARED.