angelica gigas root extract
extract of the roots of angelica gigas, apiaceae
Identification
| Name | angelica gigas root extract |
Regulatory
Physical Properties
| Food Chemicals Codex Listed | No |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | hair conditioning |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | cosmetic ingredient for skin and hair conditioning |
| Recommendation for angelica gigas root extract usage levels up to | not for fragrance use. |
| Recommendation for angelica gigas root extract flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
chao xian dang gui root extract
extract of the roots of angelica gigas, apiaceae
oni-nodake root extract
PubMed:
Single oral dose pharmacokinetics of decursin, decursinol angelate, and decursinol in rats.
PubMed:
Ultrafine Angelica gigas powder normalizes ovarian hormone levels and has antiosteoporosis properties in ovariectomized rats: particle size effect.
PubMed:
Protective effects of a novel synthetic α-lipoic acid-decursinol hybrid compound in experimentally induced transient cerebral ischemia.
PubMed:
Anti-cancer and other bioactivities of Korean Angelica gigas Nakai (AGN) and its major pyranocoumarin compounds.
PubMed:
Quantitative determination of decursin, decursinol angelate, and decursinol in mouse plasma and tumor tissue using liquid-liquid extraction and HPLC.
PubMed:
Overexpression of cinnamate 4-hydroxylase gene enhances biosynthesis of decursinol angelate in Angelica gigas hairy roots.
PubMed:
Antiplasmodial and cytotoxic activity of coumarin derivatives from dried roots of Angelica gigas Nakai in vitro.
PubMed:
Decursin inhibits growth of human bladder and colon cancer cells via apoptosis, G1-phase cell cycle arrest and extracellular signal-regulated kinase activation.
PubMed:
Biotransformation of plant secondary metabolite decursin by Mycobacterium sp. PYR1001.
PubMed:
Decursin and decursinol inhibit VEGF-induced angiogenesis by blocking the activation of extracellular signal-regulated kinase and c-Jun N-terminal kinase.
PubMed:
In vitro inhibitory potential of decursin and decursinol angelate on the catalytic activity of cytochrome P-450 1A1/2, 2D15, and 3A12 isoforms in canine hepatic microsomes.
PubMed:
Inhibitory effects of Angelicae Gigantis Radix on osteoclast formation.
PubMed:
Neuroprotective coumarins from the root of Angelica gigas: structure-activity relationships.
PubMed:
The simultaneous determination of coumarins in Angelica gigas root by high performance liquid chromatography-diode array detector coupled with electrospray ionization/mass spectrometry.
PubMed:
Decursin suppresses human androgen-independent PC3 prostate cancer cell proliferation by promoting the degradation of beta-catenin.
PubMed:
Oriental herbs as a source of novel anti-androgen and prostate cancer chemopreventive agents.
PubMed:
Potent antiandrogen and androgen receptor activities of an Angelica gigas-containing herbal formulation: identification of decursin as a novel and active compound with implications for prevention and treatment of prostate cancer.
PubMed:
A novel anticancer agent, decursin, induces G1 arrest and apoptosis in human prostate carcinoma cells.
PubMed:
Quantification of ligustilides in the roots of Angelica sinensis and related umbelliferous medicinal plants by high-performance liquid chromatography and liquid chromatography-mass spectrometry.
PubMed:
Decursinol angelate: a cytotoxic and protein kinase C activating agent from the root of Angelica gigas.
PubMed:
Decursin: a cytotoxic agent and protein kinase C activator from the root of Angelica gigas.
PubMed:
Coumarins from the root of Angelica gigas Nakai.