angelica gigas root extract

extract of the roots of angelica gigas, apiaceae

Identification

Nameangelica gigas root extract

Regulatory

Physical Properties

Food Chemicals Codex Listed No

Cosmetic Information

CosIngcosmetic data
Cosmetic Useshair conditioning

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorycosmetic ingredient for skin and hair conditioning
Recommendation for angelica gigas root extract usage levels up tonot for fragrance use.
Recommendation for angelica gigas root extract flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

angelica gigas root

Synonyms

chao xian dang gui root extract extract of the roots of angelica gigas, apiaceae oni-nodake root extract PubMed: Single oral dose pharmacokinetics of decursin, decursinol angelate, and decursinol in rats. PubMed: Ultrafine Angelica gigas powder normalizes ovarian hormone levels and has antiosteoporosis properties in ovariectomized rats: particle size effect. PubMed: Protective effects of a novel synthetic α-lipoic acid-decursinol hybrid compound in experimentally induced transient cerebral ischemia. PubMed: Anti-cancer and other bioactivities of Korean Angelica gigas Nakai (AGN) and its major pyranocoumarin compounds. PubMed: Quantitative determination of decursin, decursinol angelate, and decursinol in mouse plasma and tumor tissue using liquid-liquid extraction and HPLC. PubMed: Overexpression of cinnamate 4-hydroxylase gene enhances biosynthesis of decursinol angelate in Angelica gigas hairy roots. PubMed: Antiplasmodial and cytotoxic activity of coumarin derivatives from dried roots of Angelica gigas Nakai in vitro. PubMed: Decursin inhibits growth of human bladder and colon cancer cells via apoptosis, G1-phase cell cycle arrest and extracellular signal-regulated kinase activation. PubMed: Biotransformation of plant secondary metabolite decursin by Mycobacterium sp. PYR1001. PubMed: Decursin and decursinol inhibit VEGF-induced angiogenesis by blocking the activation of extracellular signal-regulated kinase and c-Jun N-terminal kinase. PubMed: In vitro inhibitory potential of decursin and decursinol angelate on the catalytic activity of cytochrome P-450 1A1/2, 2D15, and 3A12 isoforms in canine hepatic microsomes. PubMed: Inhibitory effects of Angelicae Gigantis Radix on osteoclast formation. PubMed: Neuroprotective coumarins from the root of Angelica gigas: structure-activity relationships. PubMed: The simultaneous determination of coumarins in Angelica gigas root by high performance liquid chromatography-diode array detector coupled with electrospray ionization/mass spectrometry. PubMed: Decursin suppresses human androgen-independent PC3 prostate cancer cell proliferation by promoting the degradation of beta-catenin. PubMed: Oriental herbs as a source of novel anti-androgen and prostate cancer chemopreventive agents. PubMed: Potent antiandrogen and androgen receptor activities of an Angelica gigas-containing herbal formulation: identification of decursin as a novel and active compound with implications for prevention and treatment of prostate cancer. PubMed: A novel anticancer agent, decursin, induces G1 arrest and apoptosis in human prostate carcinoma cells. PubMed: Quantification of ligustilides in the roots of Angelica sinensis and related umbelliferous medicinal plants by high-performance liquid chromatography and liquid chromatography-mass spectrometry. PubMed: Decursinol angelate: a cytotoxic and protein kinase C activating agent from the root of Angelica gigas. PubMed: Decursin: a cytotoxic agent and protein kinase C activator from the root of Angelica gigas. PubMed: Coumarins from the root of Angelica gigas Nakai.