vitexin 2-O-rhamnoside
apigenin-8-C-glucoside-2'-rhamnoside
Identification
| Name | vitexin 2-O-rhamnoside |
| IUPAC | 8-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one |
| CAS Number | 64820-99-1 |
| FDA UNII | UD7Y63I5X5 |
| Molecular Formula | C27 H30 O14 |
| Molecular Weight | 578.52490000 |
| MDL Number | MFCD00143627 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 898.80 °C. @ 760.00 mm Hg (est) |
| Flash Point | 571.00 °F. TCC ( 299.50 °C. ) (est) |
| logP (o/w) | 1.860 (est) |
| Soluble in | water, 1.1e+004 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for vitexin 2-O-rhamnoside usage levels up to | not for fragrance use. |
| Recommendation for vitexin 2-O-rhamnoside flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
(1S)-1,5-
anhydro-2-O-(6-deoxy-a-L-mannopyranosyl)-1-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-8-yl]-D-glucitol
apigenin-8-C-glucoside-2'-rhamnoside
8-[(2S,3R,4S,5S,6R)-4,5-
dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
2-O-
rhamnosylvitexin
2''-O-
rhamnosylvitexin
vitexin-2''-O-rhamnoside
PubMed:
Effects of vitexin-2"-O-rhamnoside and vitexin-4"-O-glucoside on growth and oxidative stress-induced cell apoptosis of human adipose-derived stem cells.
PubMed:
Tissue distribution comparison between healthy and fatty liver rats after oral administration of hawthorn leaf extract.
PubMed:
Qualitative and quantitative analysis of phenolics in Tetrastigma hemsleyanum and their antioxidant and antiproliferative activities.
PubMed:
Nutritional and functional potential of Beta vulgaris cicla and rubra.
PubMed:
An enzyme-linked immunosorbent assay for the measurement of plasma flavonoids in mice fed apigenin-C-glycoside.
PubMed:
LC determination and pharmacokinetic study of the main phenolic components of Portulaca oleracea L. extract in rat plasma after oral administration.
PubMed:
Simultaneous determination of three polyphenols in rat plasma after orally administering hawthorn leaves extract by the HPLC method.
PubMed:
HPLC determination of five polyphenols in rat plasma after intravenous administration of hawthorn leaves extract and its application to pharmacokinetic study.
PubMed:
Simultaneous determination of vitexin-4''-O-glucoside, vitexin-2''-O-rhamnoside, rutin and vitexin from hawthorn leaves flavonoids in rat plasma by UPLC-ESI-MS/MS.
PubMed:
The pharmacokinetics of C-glycosyl flavones of Hawthorn leaf flavonoids in rat after single dose oral administration.
PubMed:
[DPPH radical scavenging activities of 31 flavonoids and phenolic acids and 10 extracts of Chinese materia medica].
PubMed:
Screening and structural characterization of alpha-glucosidase inhibitors from hawthorn leaf flavonoids extract by ultrafiltration LC-DAD-MS(n) and SORI-CID FTICR MS.
PubMed:
HPLC determination of eight polyphenols in the leaves of Crataegus pinnatifida Bge. var. major.
PubMed:
Influence of the extraction mode on the yield of hyperoside, vitexin and vitexin-2''-O-rhamnoside from Crataegus monogyna Jacq. (hawthorn).
PubMed:
Assessment of intestinal absorption of vitexin-2''-o-rhamnoside in hawthorn leaves flavonoids in rat using in situ and in vitro absorption models.
PubMed:
4'''-Acetylvitexin-2''-O-rhamnoside, isoorientin, orientin, and 8-methoxykaempferol-3-O-glucoside as markers for the differentiation of Crataegus monogyna and Crataegus pentagyna from Crataegus laevigata (Rosaceae).
PubMed:
Determination of vitexin-2''-O-rhamnoside in rat plasma by ultra-performance liquid chromatography electrospray ionization tandem mass spectrometry and its application to pharmacokinetic study.
PubMed:
Simultaneous determination of vitexin-2"-O-glucoside, vitexin-2"-O-rhamnoside, rutin, and hyperoside in the extract of hawthorn (Crataegus pinnatifida Bge.) leaves by RP-HPLC with ultraviolet photodiode array detection.
PubMed:
High-performance liquid chromatographic determination and pharmacokinetic study of vitexin-2''-O-rhamnoside in rat plasma after intravenous administration.
PubMed:
Evaluation of the content and stability of the constituents of mother tinctures and tinctures: the case of Crataegus oxyacantha L. and Hieracium pilosella L.
PubMed:
Simultaneous determination of vitexin-4''-O-glucoside and vitexin-2''-O-rhamnoside from Hawthorn leaves flavonoids in rat plasma by HPLC method and its application to pharmacokinetic studies.
PubMed:
Chemosystematic value of flavonoids from Crataegus x macrocarpa (Rosaceae) with special emphasis on (R)- and (S)-eriodictyol-7-O-glucuronide and luteolin-7-O-glucuronide.
PubMed:
[Study on the chemical constituents of the leaves from Crataegus pinnatifida Bge. var. major N. E. Br].
PubMed:
Characterization and biological activity of the main flavonoids from Swiss Chard (Beta vulgaris subspecies cycla).
PubMed:
Applied environmental stresses to enhance the levels of polyphenolics in leaves of hawthorn plants.
PubMed:
On-line coupling of capillary isotachophoresis and zone electrophoresis for the assay of phenolic compounds in plant extracts.
PubMed:
Production of Flavonoids in Cell Cultures of Crataegus monogyna.
PubMed:
Antihepatotoxic C-glycosylflavones from the leaves of Allophyllus edulis var. edulis and gracilis.
PubMed:
Purification, characterization, and kinetic mechanism of S-adenosyl-L-methionine: vitexin 2"-O-rhamnoside 7-O-methyltransferase of Avena sativa L.