5,7,3',4',5'-pentahydroxyflavone

CAS: 520-31-0 C15 H10 O7 MW: 302.23910000

Identification

Nametricetin
IUPAC5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chromen-4-one
CAS Number520-31-0
FDA UNII5627PY99ZO
Molecular FormulaC15 H10 O7
Molecular Weight302.23910000
MDL NumberMFCD00210581
Nikkaji NumberJ11.687D
XlogP31.00 (est)

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 721.70 °C. @ 760.00 mm Hg (est)
Flash Point 532.00 °F. TCC ( 277.90 °C. ) (est)
logP (o/w) 2.710 (est)
Soluble in water, 486.3 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for tricetin usage levels up tonot for fragrance use.
Recommendation for tricetin flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

ginkgo biloba leaf lentil seed coat tea shoot

Synonyms

5,7- dihydroxy-2-(3,4,5-trihydroxyphenyl)chromen-4-one 5,7,3',4',5'- pentahydroxyflavone PubMed: How to deal with nomenclatoral ambiguities of trivial names for natural products?--a clarifying case study exemplified for "corymbosin". PubMed: Characterisation of honeys according to their content of phenolic compounds using high performance liquid chromatography/tandem mass spectrometry. PubMed: Luteolin suppresses the differentiation of THP-1 cells through the Inhibition of NOX2 mRNA expression and the membrane translocation of p47phox. PubMed: Nobiletin attenuates metastasis via both ERK and PI3K/Akt pathways in HGF-treated liver cancer HepG2 cells. PubMed: Identification of novel dietary phytochemicals inhibiting the efflux transporter breast cancer resistance protein (BCRP/ABCG2). PubMed: Tricin biosynthesis during growth of wheat under different abiotic stresses. PubMed: Palynological origin, phenolic content, and antioxidant properties of honeybee-collected pollen from Bahia, Brazil. PubMed: Functional characterization of two new members of the caffeoyl CoA O-methyltransferase-like gene family from Vanilla planifolia reveals a new class of plastid-localized O-methyltransferases. PubMed: Cloning and functional characterization of a caffeic acid O-methyltransferase from Trigonella foenum-graecum L. PubMed: The membrane transport of flavonoids from Crossostephium chinense across the Caco-2 monolayer. PubMed: Tricetin, a dietary flavonoid, induces apoptosis through the reactive oxygen species/c-Jun NH2-terminal kinase pathway in human liver cancer cells. PubMed: Structure-function relationships of wheat flavone O-methyltransferase: Homology modeling and site-directed mutagenesis. PubMed: Antimicrobial activity of Inga fendleriana extracts and isolated flavonoids. PubMed: [Bioactivity guided isolation of alpha-glucosidase inhibitor from whole herbs of Crossostephium chinense]. PubMed: Tricetin, a dietary flavonoid, inhibits proliferation of human breast adenocarcinoma mcf-7 cells by blocking cell cycle progression and inducing apoptosis. PubMed: Poly (ADP-ribose) polymerase-1-inhibiting flavonoids attenuate cytokine release in blood from male patients with chronic obstructive pulmonary disease or type 2 diabetes. PubMed: Inhibition of LPS-induced pulmonary inflammation by specific flavonoids. PubMed: Biochemical characterization of a putative wheat caffeic acid O-methyltransferase. PubMed: [Study on chemical constituents from stem of Dendrobium aphyllum]. PubMed: Structure-activity relationships of wheat flavone O-methyltransferase: a homodimer of convenience. PubMed: Nanocapsule@xerogel microparticles containing sodium diclofenac: a new strategy to control the release of drugs. PubMed: Cation dependent O-methyltransferases from rice. PubMed: Dietary flavones and flavonoles are inhibitors of poly(ADP-ribose)polymerase-1 in pulmonary epithelial cells. PubMed: Sequential O-methylation of tricetin by a single gene product in wheat. PubMed: Flavonoids from Metasequoia glyptostroboides. PubMed: Glycosides of tricetin methyl ethers as chemosystematic markers in Stachys subgenus Betonica. PubMed: Flavone glucosides with immunomodulatory activity from the leaves of Pleioblastus amarus. PubMed: Quantitative high-performance liquid chromatography analyses of flavonoids in Australian Eucalyptus honeys. PubMed: Identification of lipophilic flavones and flavonols by comparative HPLC, TLC and UV spectral analysis. PubMed: Tissue factor inhibitory flavonoids from the fruits of Chaenomeles sinensis. PubMed: The unique occurrence of the flavone aglycone tricetin in Myrtaceae pollen. PubMed: On the occurrence of exudate flavonoids in the borage family (Boraginaceae). PubMed: A distinctive flavonoid chemistry for the anomalous genus Biebersteinia. PubMed: Flavonoids in monospecific eucalyptus honeys from Australia. PubMed: Identification of flavonoid markers for the botanical origin of Eucalyptus honey. PubMed: Two new flavone glycosides from paullinia pinnata PubMed: Bioactive constituents of Chinese natural medicines. II. Rhodiolae radix. (1). Chemical structures and antiallergic activity of rhodiocyanosides A and B from the underground part of Rhodiola quadrifida (Pall.) Fisch. et Mey. (Crassulaceae). PubMed: Inhibition of rat liver cyclic AMP-dependent protein kinase by flavonoids. PubMed: Metabolism of myricetin and related compounds in the rat. Metabolite formation in vivo and by the intestinal microflora in vitro.