tricetin
5,7,3',4',5'-pentahydroxyflavone
Identification
| Name | tricetin |
| IUPAC | 5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chromen-4-one |
| CAS Number | 520-31-0 |
| FDA UNII | 5627PY99ZO |
| Molecular Formula | C15 H10 O7 |
| Molecular Weight | 302.23910000 |
| MDL Number | MFCD00210581 |
| Nikkaji Number | J11.687D |
| XlogP3 | 1.00 (est) |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 721.70 °C. @ 760.00 mm Hg (est) |
| Flash Point | 532.00 °F. TCC ( 277.90 °C. ) (est) |
| logP (o/w) | 2.710 (est) |
| Soluble in | water, 486.3 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for tricetin usage levels up to | not for fragrance use. |
| Recommendation for tricetin flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
5,7-
dihydroxy-2-(3,4,5-trihydroxyphenyl)chromen-4-one
5,7,3',4',5'-
pentahydroxyflavone
PubMed:
How to deal with nomenclatoral ambiguities of trivial names for natural products?--a clarifying case study exemplified for "corymbosin".
PubMed:
Characterisation of honeys according to their content of phenolic compounds using high performance liquid chromatography/tandem mass spectrometry.
PubMed:
Luteolin suppresses the differentiation of THP-1 cells through the Inhibition of NOX2 mRNA expression and the membrane translocation of p47phox.
PubMed:
Nobiletin attenuates metastasis via both ERK and PI3K/Akt pathways in HGF-treated liver cancer HepG2 cells.
PubMed:
Identification of novel dietary phytochemicals inhibiting the efflux transporter breast cancer resistance protein (BCRP/ABCG2).
PubMed:
Tricin biosynthesis during growth of wheat under different abiotic stresses.
PubMed:
Palynological origin, phenolic content, and antioxidant properties of honeybee-collected pollen from Bahia, Brazil.
PubMed:
Functional characterization of two new members of the caffeoyl CoA O-methyltransferase-like gene family from Vanilla planifolia reveals a new class of plastid-localized O-methyltransferases.
PubMed:
Cloning and functional characterization of a caffeic acid O-methyltransferase from Trigonella foenum-graecum L.
PubMed:
The membrane transport of flavonoids from Crossostephium chinense across the Caco-2 monolayer.
PubMed:
Tricetin, a dietary flavonoid, induces apoptosis through the reactive oxygen species/c-Jun NH2-terminal kinase pathway in human liver cancer cells.
PubMed:
Structure-function relationships of wheat flavone O-methyltransferase: Homology modeling and site-directed mutagenesis.
PubMed:
Antimicrobial activity of Inga fendleriana extracts and isolated flavonoids.
PubMed:
[Bioactivity guided isolation of alpha-glucosidase inhibitor from whole herbs of Crossostephium chinense].
PubMed:
Tricetin, a dietary flavonoid, inhibits proliferation of human breast adenocarcinoma mcf-7 cells by blocking cell cycle progression and inducing apoptosis.
PubMed:
Poly (ADP-ribose) polymerase-1-inhibiting flavonoids attenuate cytokine release in blood from male patients with chronic obstructive pulmonary disease or type 2 diabetes.
PubMed:
Inhibition of LPS-induced pulmonary inflammation by specific flavonoids.
PubMed:
Biochemical characterization of a putative wheat caffeic acid O-methyltransferase.
PubMed:
[Study on chemical constituents from stem of Dendrobium aphyllum].
PubMed:
Structure-activity relationships of wheat flavone O-methyltransferase: a homodimer of convenience.
PubMed:
Nanocapsule@xerogel microparticles containing sodium diclofenac: a new strategy to control the release of drugs.
PubMed:
Cation dependent O-methyltransferases from rice.
PubMed:
Dietary flavones and flavonoles are inhibitors of poly(ADP-ribose)polymerase-1 in pulmonary epithelial cells.
PubMed:
Sequential O-methylation of tricetin by a single gene product in wheat.
PubMed:
Flavonoids from Metasequoia glyptostroboides.
PubMed:
Glycosides of tricetin methyl ethers as chemosystematic markers in Stachys subgenus Betonica.
PubMed:
Flavone glucosides with immunomodulatory activity from the leaves of Pleioblastus amarus.
PubMed:
Quantitative high-performance liquid chromatography analyses of flavonoids in Australian Eucalyptus honeys.
PubMed:
Identification of lipophilic flavones and flavonols by comparative HPLC, TLC and UV spectral analysis.
PubMed:
Tissue factor inhibitory flavonoids from the fruits of Chaenomeles sinensis.
PubMed:
The unique occurrence of the flavone aglycone tricetin in Myrtaceae pollen.
PubMed:
On the occurrence of exudate flavonoids in the borage family (Boraginaceae).
PubMed:
A distinctive flavonoid chemistry for the anomalous genus Biebersteinia.
PubMed:
Flavonoids in monospecific eucalyptus honeys from Australia.
PubMed:
Identification of flavonoid markers for the botanical origin of Eucalyptus honey.
PubMed:
Two new flavone glycosides from paullinia pinnata
PubMed:
Bioactive constituents of Chinese natural medicines. II. Rhodiolae radix. (1). Chemical structures and antiallergic activity of rhodiocyanosides A and B from the underground part of Rhodiola quadrifida (Pall.) Fisch. et Mey. (Crassulaceae).
PubMed:
Inhibition of rat liver cyclic AMP-dependent protein kinase by flavonoids.
PubMed:
Metabolism of myricetin and related compounds in the rat. Metabolite formation in vivo and by the intestinal microflora in vitro.