scutellarein

4H-1- benzopyran-4-one, 5,6,7-trihydroxy-2-(4-hydroxyphenyl)- 6- hydroxyapigenin 4',5,6,7- tetrahydroxyflavanone 5,6,7,4'- tetrahydroxyflavone 5,6,7- trihydroxy-2-(4-hydroxyphenyl)chromen-4-one PubMed: Chemical fingerprint and metabolic profile analysis of Citrus reticulate 'Chachi' decoction by HPLC-PDA-IT-MS(n) and HPLC-Quadrupole-Orbitrap-MS method. PubMed: Inhibitory Effects of Scutellarein on Proliferation of Human Lung Cancer A549 Cells through ERK and NFκB Mediated by the EGFR Pathway. PubMed: Effect of light, methyl jasmonate and cyclodextrin on production of phenolic compounds in hairy root cultures of Scutellaria lateriflora. PubMed: Nanosuspension Development of Scutellarein as an Active and Rapid Orally Absorbed Precursor of its BCS Class IV Glycoside Scutellarin. PubMed: Phytotoxic potential of Onopordum acanthium L. (Asteraceae). PubMed: Simultaneous determination of three glucuronide conjugates of scutellarein in rat plasma by LC-MS/MS for pharmacokinetic study of breviscapine. PubMed: Analysis of the transcriptome of Erigeron breviscapus uncovers putative scutellarin and chlorogenic acids biosynthetic genes and genetic markers. PubMed: Bioactive diterpenoids and flavonoids from the aerial parts of Scoparia dulcis. PubMed: The effects of wine-processing on ascending and descending: The distribution of flavonoids in rat tissues after oral administration of crude and wine-processed Radix scutellariae. PubMed: Syk/Src-targeted anti-inflammatory activity of Codariocalyx motorius ethanolic extract. PubMed: The influence of selected flavonoids from the leaves of Cirsium palustre (L.) Scop. on collagen expression in human skin fibroblasts. PubMed: [Non-taxoid chemical constituents from needles of Taxus cuspidata]. PubMed: Host-guest inclusion system of scutellarein with 2-hydroxypropyl-beta-cyclodextrin: preparation, characterization, and anticancer activity. PubMed: Influence of the gastrointestinal microflora and efflux transporters on the absorption of scutellarin and scutellarein. PubMed: Neuroprotective effects of scutellarin and scutellarein on repeatedly cerebral ischemia-reperfusion in rats. PubMed: In vitro evidence of possible influence of scutellarein towards bile acids' metabolism. PubMed: Antioxidant capacity of the leaf extract obtained from Arrabidaea chica cultivated in Southern Brazil. PubMed: Two new phenolic glycosides from Gnaphalium affine D. Don and their anti-complementary activity. PubMed: [Study on the chemical constituents in Pouzolzia zeylanica]. PubMed: Comparison of inhibition capability of scutellarein and scutellarin towards important liver UDP-glucuronosyltransferase (UGT) isoforms. PubMed: Effect of Siam weed extract and its bioactive component scutellarein tetramethyl ether on anti-inflammatory activity through NF-κB pathway. PubMed: Identification of flavone glucuronide isomers by metal complexation and tandem mass spectrometry: regioselectivity of uridine 5'-diphosphate-glucuronosyltransferase isozymes in the biotransformation of flavones. PubMed: Polar constituents composition of endemic Sideritis italica (MILL.) GREUTER et BURTER from Central Italy. PubMed: Design, synthesis and biological evaluation of glucose-containing scutellarein derivatives as neuroprotective agents based on metabolic mechanism of scutellarin in vivo. PubMed: Mannich bases of scutellarein as thrombin-inhibitors: design, synthesis, biological activity and solubility. PubMed: Phytochemical study of polyphenols in Perilla Frutescens as an antioxidant. PubMed: Synthesis and protective effect of scutellarein on focal cerebral ischemia/reperfusion in rats. PubMed: Benzoxazinoids from Scoparia dulcis (sweet broomweed) with antiproliferative activity against the DU-145 human prostate cancer cell line. PubMed: Development of chemical inhibitors of the SARS coronavirus: viral helicase as a potential target. PubMed: A Review on the Taxonomy, Ethnobotany, Chemistry and Pharmacology of Oroxylum indicum Vent. PubMed: A set of regioselective O-methyltransferases gives rise to the complex pattern of methoxylated flavones in sweet basil. PubMed: Mechanistic studies on the absorption and disposition of scutellarin in humans: selective OATP2B1-mediated hepatic uptake is a likely key determinant for its unique pharmacokinetic characteristics. PubMed: In vitro and in vivo structure and activity relationship analysis of polymethoxylated flavonoids: identifying sinensetin as a novel antiangiogenesis agent. PubMed: Identification of myricetin and scutellarein as novel chemical inhibitors of the SARS coronavirus helicase, nsP13. PubMed: Identification and analysis of the active phytochemicals from the anti-cancer botanical extract Bezielle. PubMed: [Flavonoids and nor-sesquiterpenes of Pedicularis densispica]. PubMed: Polyphenolic compounds from flowers of Hibiscus rosa-sinensis Linn. and their inhibitory effect on alkaline phosphatase enzyme activity in vitro. PubMed: Synthesis and bio-activity evaluation of scutellarein as a potent agent for the therapy of ischemic cerebrovascular disease. PubMed: Effect of flavonoids from Prosthechea michuacana on carbon tetrachloride induced acute hepatotoxicity in mice. PubMed: Efficient synthesis of scutellarein. PubMed: Comparison of different extraction procedures for the comprehensive characterization of bioactive phenolic compounds in Rosmarinus officinalis by reversed-phase high-performance liquid chromatography with diode array detection coupled to electrospray time-of-flight mass spectrometry. PubMed: Absorption and disposition of scutellarin in rats: a pharmacokinetic explanation for the high exposure of its isomeric metabolite. PubMed: [Design, synthesis and anti-oxidative evaluation of L-amino acid prodrugs of scutellarein]. PubMed: In-line monitoring of extraction process of scutellarein from Erigeron breviscapus (vant.) Hand-Mazz based on qualitative and quantitative uses of near-infrared spectroscopy. PubMed: Intestinal transport of scutellarein and scutellarin and first-pass metabolism by UDP-glucuronosyltransferase-mediated glucuronidation of scutellarein and hydrolysis of scutellarin. PubMed: Metabolic and pharmacokinetic studies of scutellarin in rat plasma, urine, and feces. PubMed: Inhibition and disaggregation of α-synuclein oligomers by natural polyphenolic compounds. PubMed: Monitoring of antisolvent crystallization of sodium scutellarein by combined FBRM-PVM-NIR. PubMed: Preparative separation of four individual flavonoids in Scutellaria barbata D. Don based on high selectivity polymeric adsorbents with different polarities. PubMed: Trans-chalcone: a novel small molecule inhibitor of mammalian alpha-amylase. PubMed: [Absorption and transportation characteristics of scutellarin and scutellarein across Caco-2 monolayer model]. PubMed: Comprehensive review of Clerodendrum phlomidis: a traditionally used bitter. PubMed: [Advances in studies on pharmacokinetics of scutellarin and scutellarein]. PubMed: Flavones and phenylpropanoids from a sedative extract of Lantana trifolia L. PubMed: Separation and purification of two flavone glucuronides from Erigeron multiradiatus (Lindl.) Benth with macroporous resins. PubMed: CYP1-mediated antiproliferative activity of dietary flavonoids in MDA-MB-468 breast cancer cells. PubMed: Activity of ladanein on leukemia cell lines and its occurrence in Marrubium vulgare. PubMed: [Chemical constituents from Hedyotis diffusa]. PubMed: Antioxidant activities of polyphenols extracted from Perilla frutescens varieties. PubMed: Mechanism of CYP2C9 inhibition by flavones and flavonols. PubMed: The constituents of Anisomeles indica and their anti-inflammatory activities. PubMed: In vitro antitumor mechanisms of various Scutellaria extracts and constituent flavonoids. PubMed: Flavonoids and cinnamic acid derivatives as inhibitors of 17beta-hydroxysteroid dehydrogenase type 1. PubMed: Flavones and flavone glycosides from Halophila johnsonii. PubMed: Anti-inflammatory activity of the extracts and fractions from Erigeron multiradiatus through bioassay-guided procedures. PubMed: Scutellarein inhibits hypoxia- and moderately-high glucose-induced proliferation and VEGF expression in human retinal endothelial cells. PubMed: Metabolites of scutellarein in rat plasma. PubMed: Inhibitory effect of Erigeron breviscapus extract and its flavonoid components on GABA shunt enzymes. PubMed: Identification and quantification of flavonoids of Mexican oregano (Lippia graveolens) by LC-DAD-ESI/MS analysis. PubMed: Isolation and identification of ten metabolites of breviscapine in rat urine. PubMed: Identification of polymethoxylated flavones from green tangerine peel (Pericarpium Citri Reticulatae Viride) by chromatographic and spectroscopic techniques. PubMed: Two major urinary metabolites of scutellarin in rats. PubMed: [Study on bile excretion of scutellarein]. PubMed: Pharmacokinetics and metabolism of the flavonoid scutellarin in humans after a single oral administration. PubMed: Use of the pig caecum model to mimic the human intestinal metabolism of hispidulin and related compounds. PubMed: Pharmacokinetics of scutellarin and its aglycone conjugated metabolites in rats. PubMed: Inhibitory effects of a chemically standardized extract from Scutellaria barbata in human colon cancer cell lines, LoVo. PubMed: Determination of aglycone conjugated metabolites of scutellarin in rat plasma by HPLC. PubMed: Validation of an HPLC method for the determination of scutellarin in rat plasma and its pharmacokinetics. PubMed: Antioxidant activity of citrus limonoids, flavonoids, and coumarins. PubMed: [Determination of scutellarin and rutin in Shenfukang capsules by reversed-phase high performance liquid chromatography]. PubMed: Antagonistic effect of scutellarin on the toxicity of selenium in rat livers. PubMed: Protection against hydrogen peroxide-induced cytotoxicity in PC12 cells by scutellarin. PubMed: Study on pharmacokinetics of scutellarin in rabbits. PubMed: Metabolism of apigenin by rat liver phase I and phase ii enzymes and by isolated perfused rat liver. PubMed: Protective effects of scutellarin on superoxide-induced oxidative stress in rat cortical synaptosomes. PubMed: Study on metabolism of scutellarin in rats by HPLC-MS and HPLC-NMR. PubMed: Variations in lipophilic and vacuolar flavonoids among European Pulicaria species. PubMed: [Recognition of three classes of skullcaps by FTIR spectroscopy combined with artificial neural networks]. PubMed: 6-hydroxyflavonoids as alpha-glucosidase inhibitors from marjoram (Origanum majorana) leaves. PubMed: Identification of lipophilic flavones and flavonols by comparative HPLC, TLC and UV spectral analysis. PubMed: [Study on effects of scutellarin on scavenging reactive oxygen]. PubMed: [Studies on flavone constituents of Erigeron breviscapus (Vant.) Hand.-Mazz]. PubMed: Structure-activity relationships of flavonoids, isolated from Scutellaria baicalensis, binding to benzodiazepine site of GABA(A) receptor complex. PubMed: Scutellarein 4'-methyl ether glycosides as taxonomic markers in Teucridium and Tripora (Lamiaceae, Ajugoideae). PubMed: Ventricular remodeling by Scutellarein treatment in spontaneously hypertensive rats. PubMed: The role of lipophilic and polar flavonoids in the classification of temperate members of the Anthemideae. PubMed: Effects of Scutellarein on diabetic rat aorta. PubMed: Foliar flavonoids of Annonaceae from Brazil: taxonomic significance. PubMed: Cloning and expression of UDP-glucose: flavonoid 7-O-glucosyltransferase from hairy root cultures of Scutellaria baicalensis. PubMed: Purification and characterization of UDP-glucuronate: baicalein 7-O-glucuronosyltransferase from Scutellaria baicalensis Georgi. cell suspension cultures. PubMed: Metabolites of orally administered Perilla frutescens extract in rats and humans. PubMed: Interaction of flavones from the roots of Scutellaria baicalensis with the benzodiazepine site. PubMed: The flavonoids of Tanacetum parthenium and T. vulgare and their anti-inflammatory properties. PubMed: Simultaneous separation of flavanone glycosides and polymethoxylated flavones in citrus juices using liquid chromatography. PubMed: Influence of a series of natural flavonoids on free radical generating systems and oxidative stress. PubMed: Effects of flavonoids on Naja naja and human recombinant synovial phospholipases A2 and inflammatory responses in mice. PubMed: Diglucuronoflavones from purple leaves of Perilla ocimoides. PubMed: Effects of flavonoids on cyclic AMP phosphodiesterase and lipid mobilization in rat adipocytes. PubMed: Inhibition of reverse transcriptases by flavonoids. PubMed: C18 solid-phase isolation and high-performance liquid chromatography/ultraviolet diode array determination of fully methoxylated flavones in citrus juices.