saponarin
isovitexin-7-O-glucoside
Identification
| Name | saponarin |
| IUPAC | 5-hydroxy-2-(4-hydroxyphenyl)-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-7-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]o |
| CAS Number | 20310-89-8 |
| FDA UNII | 3081Z76OX9 |
| Molecular Formula | C27 H30 O15 |
| Molecular Weight | 594.52410000 |
| Nikkaji Number | J94.482C |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 919.50 °C. @ 760.00 mm Hg (est) |
| Flash Point | 582.00 °F. TCC ( 305.40 °C. ) (est) |
| logP (o/w) | -1.210 (est) |
| Soluble in | water, 4.116e+004 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for saponarin usage levels up to | not for fragrance use. |
| Recommendation for saponarin flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
4H-1-
benzopyran-4-one, 3-((6-O-(6-deoxy-beta-L-mannofuranosyl)-beta-O-galactofuranosyl)oxy)-7-((6-deoxy-beta-L-mannopyranosyl)oxy)-5-hydroxy-2-(4-hydroxyphenyl)-
saponaretin-7-O-glucoside
iso
vitexin-7-O-glucoside
PubMed:
Preparation of two flavonoid glycosides with unique structures from barley seedlings by membrane separation technology and preparative high-performance liquid chromatography.
PubMed:
Saponarin from barley sprouts inhibits NF-κB and MAPK on LPS-induced RAW 264.7 cells.
PubMed:
Protective effects of the apigenin-O/C-diglucoside saponarin from Gypsophila trichotoma on carbone tetrachloride-induced hepatotoxicity in vitro/in vivo in rats.
PubMed:
Hepatoprotective and antioxidant effects of saponarin, isolated from Gypsophila trichotoma Wend. on paracetamol-induced liver damage in rats.
PubMed:
First synthesis of saponarin, 6-C- and 7-O-di-β-D-glucosylapigenin.
PubMed:
Flavonoids with potent antioxidant activity found in young green barley leaves.
PubMed:
Bioflavonoid profile of citrus juices from Greece.
PubMed:
HPLC determination of flavonoid glycosides in Mongolian Dianthus versicolor Fisch. (Caryophyllaceae) compared with quantification by UV spectrophotometry.
PubMed:
Hepatoprotective effects of saponarin, isolated from Gypsophila trichotoma Wend. on cocaine-induced oxidative stress in rats.
PubMed:
Flavonoid C- and O-glycosides from the Mongolian medicinal plant Dianthus versicolor Fisch.
PubMed:
Distribution of free amino acids, flavonoids, total phenolics, and antioxidative activities of Jujube (Ziziphus jujuba) fruits and seeds harvested from plants grown in Korea.
PubMed:
Quantification of flavonoid glycosides in an aqueous extract from the traditional Mongolian medicinal plant Dianthus versicolor FISCH.
PubMed:
Phytochemical investigation and biological studies of Bombax malabaricum flowers.
PubMed:
Extracts from the Mongolian traditional medicinal plants Dianthus versicolorFisch. and Lilium pumilum Delile stimulate bile flow in an isolated perfused rat liver model.
PubMed:
The effect of isosaponarin isolated from wasabi leaf on collagen synthesis in human fibroblasts and its underlying mechanism.
PubMed:
Proteome and flavonoid analysis reveals distinct responses of epidermal tissue and whole leaves upon UV-B radiation of barley (Hordeum vulgare L.) seedlings.
PubMed:
Dolichandroside A, a new alpha-glucosidase inhibitor and DPPH free-radical scavenger from Dolichandrone falcata seem.
PubMed:
Hypoglycemic activity of the antioxidant saponarin, characterized as alpha-glucosidase inhibitor present in Tinospora cordifolia.
PubMed:
Further knowledge on barley (Hordeum vulgare L.) leaves O-glycosyl-C-glycosyl flavones by liquid chromatography-UV diode-array detection-electrospray ionisation mass spectrometry.
PubMed:
Antioxidant activity of flavonoids isolated from young green barley leaves toward biological lipid samples.
PubMed:
Phenolic constituents in dried flowers of aloe vera (Aloe barbadensis) and their in vitro antioxidative capacity.
PubMed:
Flavonoid biosynthesis in barley primary leaves requires the presence of the vacuole and controls the activity of vacuolar flavonoid transport.
PubMed:
Antioxidant phenolic glucosides from Gentiana piasezkii.
PubMed:
Contribution of phenolic compounds to the UV-B screening capacity of developing barley primary leaves in relation to DNA damage and repair under elevated UV-B levels.
PubMed:
The mis-identification of the major antioxidant flavonoids in young barley (Hordeum vulgare) leaves.
PubMed:
Jasmonate-induced changes in flavonoid metabolism in barley (Hordeum vulgare) leaves.
PubMed:
Flavone glucoside uptake into barley mesophyll and Arabidopsis cell culture vacuoles. Energization occurs by H(+)-antiport and ATP-binding cassette-type mechanisms.
PubMed:
Acylated flavone C-glycosides from Cucumis sativus.
PubMed:
Antihepatotoxic C-glycosylflavones from the leaves of Allophyllus edulis var. edulis and gracilis.
PubMed:
Chemical constituents of gentianaceae XXVIII: flavonoids of Enicostemma hyssopifolium (Willd.) Verd.
PubMed:
Uridinediphosphate-glucose: Isovitexin 7-O-glucosyltransferase from barley protoplasts: Subcellular localization.
PubMed:
The flavonoid constituents of barley (Horedum vulgare). I. Saponarin.