saponarin

isovitexin-7-O-glucoside

CAS: 20310-89-8 C27 H30 O15 MW: 594.52410000

Identification

Namesaponarin
IUPAC5-hydroxy-2-(4-hydroxyphenyl)-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-7-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]o
CAS Number20310-89-8
FDA UNII3081Z76OX9
Molecular FormulaC27 H30 O15
Molecular Weight594.52410000
Nikkaji NumberJ94.482C

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 919.50 °C. @ 760.00 mm Hg (est)
Flash Point 582.00 °F. TCC ( 305.40 °C. ) (est)
logP (o/w) -1.210 (est)
Soluble in water, 4.116e+004 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for saponarin usage levels up tonot for fragrance use.
Recommendation for saponarin flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

barley leaf barley shoot cucumber

Synonyms

4H-1- benzopyran-4-one, 3-((6-O-(6-deoxy-beta-L-mannofuranosyl)-beta-O-galactofuranosyl)oxy)-7-((6-deoxy-beta-L-mannopyranosyl)oxy)-5-hydroxy-2-(4-hydroxyphenyl)- saponaretin-7-O-glucoside iso vitexin-7-O-glucoside PubMed: Preparation of two flavonoid glycosides with unique structures from barley seedlings by membrane separation technology and preparative high-performance liquid chromatography. PubMed: Saponarin from barley sprouts inhibits NF-κB and MAPK on LPS-induced RAW 264.7 cells. PubMed: Protective effects of the apigenin-O/C-diglucoside saponarin from Gypsophila trichotoma on carbone tetrachloride-induced hepatotoxicity in vitro/in vivo in rats. PubMed: Hepatoprotective and antioxidant effects of saponarin, isolated from Gypsophila trichotoma Wend. on paracetamol-induced liver damage in rats. PubMed: First synthesis of saponarin, 6-C- and 7-O-di-β-D-glucosylapigenin. PubMed: Flavonoids with potent antioxidant activity found in young green barley leaves. PubMed: Bioflavonoid profile of citrus juices from Greece. PubMed: HPLC determination of flavonoid glycosides in Mongolian Dianthus versicolor Fisch. (Caryophyllaceae) compared with quantification by UV spectrophotometry. PubMed: Hepatoprotective effects of saponarin, isolated from Gypsophila trichotoma Wend. on cocaine-induced oxidative stress in rats. PubMed: Flavonoid C- and O-glycosides from the Mongolian medicinal plant Dianthus versicolor Fisch. PubMed: Distribution of free amino acids, flavonoids, total phenolics, and antioxidative activities of Jujube (Ziziphus jujuba) fruits and seeds harvested from plants grown in Korea. PubMed: Quantification of flavonoid glycosides in an aqueous extract from the traditional Mongolian medicinal plant Dianthus versicolor FISCH. PubMed: Phytochemical investigation and biological studies of Bombax malabaricum flowers. PubMed: Extracts from the Mongolian traditional medicinal plants Dianthus versicolorFisch. and Lilium pumilum Delile stimulate bile flow in an isolated perfused rat liver model. PubMed: The effect of isosaponarin isolated from wasabi leaf on collagen synthesis in human fibroblasts and its underlying mechanism. PubMed: Proteome and flavonoid analysis reveals distinct responses of epidermal tissue and whole leaves upon UV-B radiation of barley (Hordeum vulgare L.) seedlings. PubMed: Dolichandroside A, a new alpha-glucosidase inhibitor and DPPH free-radical scavenger from Dolichandrone falcata seem. PubMed: Hypoglycemic activity of the antioxidant saponarin, characterized as alpha-glucosidase inhibitor present in Tinospora cordifolia. PubMed: Further knowledge on barley (Hordeum vulgare L.) leaves O-glycosyl-C-glycosyl flavones by liquid chromatography-UV diode-array detection-electrospray ionisation mass spectrometry. PubMed: Antioxidant activity of flavonoids isolated from young green barley leaves toward biological lipid samples. PubMed: Phenolic constituents in dried flowers of aloe vera (Aloe barbadensis) and their in vitro antioxidative capacity. PubMed: Flavonoid biosynthesis in barley primary leaves requires the presence of the vacuole and controls the activity of vacuolar flavonoid transport. PubMed: Antioxidant phenolic glucosides from Gentiana piasezkii. PubMed: Contribution of phenolic compounds to the UV-B screening capacity of developing barley primary leaves in relation to DNA damage and repair under elevated UV-B levels. PubMed: The mis-identification of the major antioxidant flavonoids in young barley (Hordeum vulgare) leaves. PubMed: Jasmonate-induced changes in flavonoid metabolism in barley (Hordeum vulgare) leaves. PubMed: Flavone glucoside uptake into barley mesophyll and Arabidopsis cell culture vacuoles. Energization occurs by H(+)-antiport and ATP-binding cassette-type mechanisms. PubMed: Acylated flavone C-glycosides from Cucumis sativus. PubMed: Antihepatotoxic C-glycosylflavones from the leaves of Allophyllus edulis var. edulis and gracilis. PubMed: Chemical constituents of gentianaceae XXVIII: flavonoids of Enicostemma hyssopifolium (Willd.) Verd. PubMed: Uridinediphosphate-glucose: Isovitexin 7-O-glucosyltransferase from barley protoplasts: Subcellular localization. PubMed: The flavonoid constituents of barley (Horedum vulgare). I. Saponarin.