rhoeadine
rheadan, 8-methoxy-16-methyl-2,3:10,11-bis(methylenebis(oxy))-, (8-beta)-
Identification
| Name | rhoeadine |
| CAS Number | 2718-25-4 |
| FDA UNII | 9Q9C65WH3B |
| Molecular Formula | C21 H21 N O6 |
| Molecular Weight | 383.40057000 |
| Nikkaji Number | J7.900F |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 489.30 °C. @ 760.00 mm Hg (est) |
| Flash Point | 289.00 °F. TCC ( 142.90 °C. ) (est) |
| logP (o/w) | 3.920 (est) |
| Soluble in | water, 221.8 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | intravenous-rat LD50 530 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | pharmaceuticals / chemical synthisis |
| Recommendation for rhoeadine usage levels up to | not for fragrance use. |
| Recommendation for rhoeadine flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
8-beta-
methoxy-16-methyl-2,3:10,11-bis(methylenebis(oxy))rheadan
rheadan, 8-methoxy-16-methyl-2,3:10,11-bis(methylenebis(oxy))-, (8-beta)-
rhoeadin
PubMed:
Dioxygenases catalyze O-demethylation and O,O-demethylenation with widespread roles in benzylisoquinoline alkaloid metabolism in opium poppy.
PubMed:
Genetic and chemical components analysis of Papaver setigerum naturalized in Korea.
PubMed:
Isolation of triniifoline, miltanthaline and some medicinally important alkaloids from Papaver triniifolium.
PubMed:
Comparison of chemical and botanical studies of Turkish papaver belonging to the section pilosa.
PubMed:
Alkaloids from Papaver triniifolium of Turkish Origin1.
PubMed:
Alkaloids from Papaver cylindricum.
PubMed:
[Isolation and chemistry of the alkaloids from plants of the Papaveraceae, LXXXI Glauca - a new section of the genus Papaver].
PubMed:
Alkaloids from Papaver armeniacum, P. fugax and P. tauricola.
PubMed:
Alkaloids from Egyptian Papaver rhoeas.
PubMed:
[Study of the toxicity and biotransformation of rhoeadine].
PubMed:
[Studies on the alkaloids of papeveraceous plants. XXVIII. The biosynthesis of rhoeadine (author's transl)].
PubMed:
Isolation and chemistry of alkaloids from plants of the family Papaveraceae LXVII: Corydalis cava (L.) Sch. et K. (C. tuberosa DC).
PubMed:
A total synthesis of the alkaloid rhoeadine. Preliminary communication.
PubMed:
[On the structure of oreodin and oreogenin. Mass spectrometry of Rhoeadine alkaloids].
PubMed:
[On the structure of rhoeadine isomers isolated from Papaver rhoeas].
PubMed:
[Hofmann degradation of rhoeadine].