maclurin
methanone, (3,4-dihydroxyphenyl)(2,4,6-trihydroxyphenyl)-
Identification
| Name | maclurin |
| IUPAC | (3,4-dihydroxyphenyl)-(2,4,6-trihydroxyphenyl)methanone |
| CAS Number | 519-34-6 |
| EINECS | 208-268-2 |
| FDA UNII | 27KFF3PMTU |
| Molecular Formula | C13 H10 O6 |
| Molecular Weight | 262.21790000 |
| MDL Number | MFCD03939026 |
| Nikkaji Number | J182.278K |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 222.50 °C. @ 760.00 mm Hg |
| Boiling Point | 551.10 °C. @ 760.00 mm Hg (est) |
| Flash Point | 574.00 °F. TCC ( 301.20 °C. ) (est) |
| logP (o/w) | 2.880 (est) |
| Soluble in | water, 5000 mg/L @ 14C (exp) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for maclurin usage levels up to | not for fragrance use. |
| Recommendation for maclurin flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
benzophenone, 2,3',4,4',6-pentahydroxy- (8CI)
(3,4-
dihydroxyphenyl)-(2,4,6-trihydroxyphenyl)methanone
(3,4-
dihydroxyphenyl)(2,4,6-trihydroxyphenyl)methanone
laguncurin
methanone, (3,4-dihydroxyphenyl)(2,4,6-trihydroxyphenyl)-
moritannic acid
2,3',4,4',6-
pentahydroxybenzophenone
PubMed:
Maclurin protects against hydroxyl radical-induced damages to mesenchymal stem cells: Antioxidant evaluation and mechanistic insight.
PubMed:
Isolation of xanthone and benzophenone derivatives from Cyclopia genistoides (L.) Vent. (honeybush) and their pro-apoptotic activity on synoviocytes from patients with rheumatoid arthritis.
PubMed:
Note on the supposed production of maclurin from acacatechin.
PubMed:
Comprehensive phenolic profiling of Cyclopia genistoides (L.) Vent. by LC-DAD-MS and -MS/MS reveals novel xanthone and benzophenone constituents.
PubMed:
MAO-A inhibition profiles of some benzophenone glucosides from Gentiana verna subsp. pontica.
PubMed:
Yeast-mediated xanthone synthesis through oxidative intramolecular cyclization.
PubMed:
Antioxidant and antityrosinase activity of mulberry (Morus alba L.) twigs and root bark.
PubMed:
Characterization of bioactive compounds from raw and ripe Mangifera indica L. peel extracts.
PubMed:
Isolation of the Maclura pomifera hemagglutinin on a deoxymelibiotol affinity support and preliminary characterization by buffer electrofocusing and high-performance liquid chromatography.
PubMed:
An in vitro study of the toxic effects of Stachybotrys chartarum metabolites on lung cells.
PubMed:
Lectin and other histochemical studies of the articular cartilage and the chondro-osseous junction of the normal human knee joint.
PubMed:
Polyvalent GalNAcalpha1-->Ser/Thr (Tn) and Galbeta1-->3GalNAcalpha1-->Ser/Thr (T alpha) as the most potent recognition factors involved in Maclura pomifera agglutinin-glycan interactions.
PubMed:
Characterization of gallotannins and benzophenone derivatives from mango (Mangifera indica L. cv. 'Tommy Atkins') peels, pulp and kernels by high-performance liquid chromatography/electrospray ionization mass spectrometry.
PubMed:
Two-dimensional cell sheet manipulation of heterotypically co-cultured lung cells utilizing temperature-responsive culture dishes results in long-term maintenance of differentiated epithelial cell functions.
PubMed:
Effects of sodium diethyldithiocarbamate on type II pulmonary epithelial cells in vitro.
PubMed:
The conformation of the T-antigen disaccharide bound to Maclura pomifera agglutinin in aqueous solution.
PubMed:
Lectin binding studies of parotid salivary glycoproteins in Sjögren's syndrome.
PubMed:
Diversity of C-linked neoglycopeptides for the exploration of subsite-assisted carbohydrate binding interactions.
PubMed:
Lectins in the vulva. II. Vulvar intraepithelial neoplasia and squamous cell carcinoma.
PubMed:
Structure of the complex of Maclura pomifera agglutinin and the T-antigen disaccharide, Galbeta1,3GalNAc.
PubMed:
Mass spectrometric analysis of genetic and post-translational heterogeneity in the lectins Jacalin and Maclura pomifera agglutinin.
PubMed:
On the structural differences in the membranes between ciliated bronchial and non-ciliated lymphoepithelium in rats.
PubMed:
Secretion of surfactant protein A from rat type II pneumocytes.
PubMed:
Maclura pomifera agglutinin-binding glycoconjugates on converted apatite from synthetic octacalcium phosphate implanted into subperiosteal region of mouse calvaria.
PubMed:
Isolation and immortalization of rat pre-type II cell lines.
PubMed:
Isolation and partial characterization of pneumocin, a novel apical membrane surface glycoprotein marker of rat type II cells.
PubMed:
The amino acid sequences of jacalin and the Maclura pomifera agglutinin.
PubMed:
Fetal mouse alveolar type II cells in culture express several type II cell characteristics found in vivo, together with major histocompatibility antigens.
PubMed:
Homology of the D-galactose-specific lectins from Artocarpus integrifolia and Maclura pomifera and the role of an unusual small polypeptide subunit.
PubMed:
Alveolar cell differentiation markers in human lungs.
PubMed:
Immunohistochemical properties of the endometrial and cervical adenocarcinoma.
PubMed:
Isolation of pulmonary alveolar type I cells from adult rats.
PubMed:
Improved isolation of rat lung alveolar type II cells. More representative recovery and retention of cell polarity.
PubMed:
Changes in biochemical characteristics and pattern of lectin binding of alveolar type II cells with time in culture.
PubMed:
Solid phase measurements of antibody and lectin binding to xenogenic carbohydrate antigens.
PubMed:
Xanthones and benzophenones from the stems of Garcinia multiflora.
PubMed:
Glycophorin A-mediated haemolysis of normal human erythrocytes: evidence for antigen aggregation in the pathogenesis of immune haemolysis.
PubMed:
Surface changes in type II pneumocytes isolated from rats during the cultivation.
PubMed:
Heterogeneity of the zona pellucida carbohydrate distribution in human oocytes failing to fertilize in vitro.
PubMed:
Molecular cloning of the mitogenic mannose/maltose-specific rhizome lectin from Calystegia sepium.
PubMed:
Intratracheal administration of hepatocyte growth factor/scatter factor stimulates rat alveolar type II cell proliferation in vivo.
PubMed:
Bauhinia purpurea lectin (BPA) binding of rat type I pneumocytes: alveolar epithelial alterations after radiation-induced lung injury.
PubMed:
Regulation of low-amiloride-affinity sodium channels in alveolar type II cells.
PubMed:
Lectin histochemistry of normal lung and pulmonary carcinoma.
PubMed:
Capacitated and acrosome reacted spermatozoa of goat (Capra indicus): a fluorescence and electron microscopic study.
PubMed:
Surfactant lipid uptake and secretion in type II cells in response to lectins and secretagogues.
PubMed:
Serum accelerates the loss of type II cell differentiation in vitro.
PubMed:
Expression of cell-specific markers for alveolar epithelium in fetal rat lung.
PubMed:
Crystallization and preliminary X-ray diffraction studies of the complex of Maclura pomifera agglutinin with the disaccharide Gal beta 1-3GalNAc.
PubMed:
Lectin histochemistry in rat thyroid tumours.
PubMed:
A histochemical localization on Maclura pomifera lectin during osteogenesis.
PubMed:
Identification and characterization of the pulmonary alveolar type II cell Maclura pomifera agglutinin-binding membrane glycoprotein.
PubMed:
Ultrastructural demonstration of Maclura pomifera agglutinin binding sites in the membranocystic lesions of membranous lipodystrophy (Nasu-Hakola disease).
PubMed:
Culture of differentiated and undifferentiated type II cells from fetal rat lung.
PubMed:
The separation of lymphocyte subpopulations with lectins.
PubMed:
Cellular heterogeneity in normal human urothelium: an analysis of optical properties and lectin binding.
PubMed:
Interaction of Salmonella telaviv with Maclura pomifera lectin.