lactupicrin
lactucopicrin
Identification
| Name | lactupicrin |
| IUPAC | [(3aR,4S,9aS,9bR)-9-(hydroxymethyl)-6-methyl-3-methylidene-2,7-dioxo-4,5,9a,9b-tetrahydro-3aH-azuleno[4,5-b]furan-4-yl] 2-(4-hydroxyphenyl)acetate |
| CAS Number | 65725-11-3 |
| FDA UNII | Search |
| Molecular Formula | C23 H22 O7 |
| Molecular Weight | 410.42274000 |
| Nikkaji Number | J1.583.455B |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 686.00 °C. @ 760.00 mm Hg (est) |
| Flash Point | 467.00 °F. TCC ( 241.80 °C. ) (est) |
| logP (o/w) | 2.240 (est) |
| Soluble in | water, 3777 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for lactupicrin usage levels up to | not for fragrance use. |
| Recommendation for lactupicrin flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
[(3aR,4S,9aS,9bR)-9-(
hydroxymethyl)-6-methyl-3-methylidene-2,7-dioxo-4,5,9a,9b-tetrahydro-3aH-azuleno[4,5-b]furan-4-yl] 2-(4-hydroxyphenyl)acetate
lactucopicrin
PubMed:
Sesquiterpene lactone content and overall quality of fresh-cut witloof chicory (Cichorium intybus L. var. foliosum Hegi) as affected by different washing procedures.
PubMed:
Reversed-phase ultra-high-performance liquid chromatography coupled to electrospray ionization-quadrupole-time-of-flight mass spectrometry as a powerful tool for metabolic profiling of vegetables: Lactuca sativa as an example of its application.
PubMed:
Introducing Cichorium Pumilum as a potential therapeutical agent against drug-induced benign breast tumor in rats.
PubMed:
In vitro analysis of the anthelmintic activity of forage chicory (Cichorium intybus L.) sesquiterpene lactones against a predominantly Haemonchus contortus egg population.
PubMed:
[Comparative studies in content of major active compositions in different parts of Cichorium glandulosum].
PubMed:
Isolation of three sesquiterpene lactones from the roots of Cichorium glandulosum Boiss. et Huet. by high-speed counter-current chromatography.
PubMed:
Analgesic and sedative activities of lactucin and some lactucin-like guaianolides in mice.
PubMed:
Influence of cultivation site on sesquiterpene lactone composition of forage chicory (Cichorium intybus L.).
PubMed:
Application of the in combo screening approach for the discovery of non-alkaloid acetylcholinesterase inhibitors from Cichorium intybus.
PubMed:
Antimalarial activity of lactucin and lactucopicrin: sesquiterpene lactones isolated from Cichorium intybus L.
PubMed:
Sesquiterpene lactones in a hairy root culture of Cichorium intybus.
PubMed:
Guaianolides from Cichorium intybus and structure revision of Cichorium sesquiterpene lactones.
PubMed:
Metabolite profiling of sesquiterpene lactones from Lactuca species. Major latex components are novel oxalate and sulfate conjugates of lactucin and its derivatives.
PubMed:
(+)-Germacrene A biosynthesis . The committed step in the biosynthesis of bitter sesquiterpene lactones in chicory
PubMed:
Guaianolides from Lactuca saligna.
PubMed:
[Oxidation of lactucopicrin and p-hydroxyphenylacetic acid by peroxydase].
PubMed:
[Research on the preparation of lactucin and lactucopicrin from Lactuca virosa plants. 15. On the enzymatic and non-enzymatic oxidation of therapeutically active plant substances].
PubMed:
[Fermentative destruction of lactucopicrin. 1. On oxydation of vegetable substances].