4H-furo(2,3-h)-1-benzopyran-4-one, 3-methoxy-2-phenyl- (8CI)(9CI)

CAS: 521-88-0 C18 H12 O4 MW: 292.29044000

Identification

Namekaranjin
IUPAC3-methoxy-2-phenylfuro[2,3-h]chromen-4-one
CAS Number521-88-0
EINECS208-319-9
FDA UNIIWV7IM0I02M
Molecular FormulaC18 H12 O4
Molecular Weight292.29044000
MDL NumberMFCD00017406
Nikkaji NumberJ6.616H

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 463.00 °C. @ 760.00 mm Hg (est)
Flash Point 453.00 °F. TCC ( 233.80 °C. ) (est)
logP (o/w) 3.290 (est)
Soluble in water, 18.95 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for karanjin usage levels up tonot for fragrance use.
Recommendation for karanjin flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

tephrosia purpurea

Synonyms

4H- furo(2,3-h)-1-benzopyran-4-one, 3-methoxy-2-phenyl- (8CI)(9CI) 3- methoxy-2-phenyl-4H-furo(2,3-h)(1)benzopyran-4-one 3- methoxy-2-phenylfuro[2,3-h]chromen-4-one PubMed: A new 1,2-ethanedione benzofurane derivative from Tephrosia purpurea. PubMed: Development and Validation of an LC-MS Method for Determination of Karanjin in Rat Plasma: Application to Preclinical Pharmacokinetics. PubMed: Karanjin interferes with ABCB1, ABCC1, and ABCG2. PubMed: Comparative toxicity of an acetogenin-based extract and commercial pesticides against citrus red mite. PubMed: Prevention of arthritis markers in experimental animal and inflammation signalling in macrophage by Karanjin isolated from Pongamia pinnata seed extract. PubMed: The separation of flavonoids from Pongamia pinnata using combination columns in high-speed counter-current chromatography with a three-phase solvent system. PubMed: Medicinal uses, phytochemistry and pharmacology of Pongamia pinnata (L.) Pierre: a review. PubMed: Development and Validation of an HPLC Method for Karanjin in Pongamia pinnata linn. Leaves. PubMed: Karanjin from Pongamia pinnata induces GLUT4 translocation in skeletal muscle cells in a phosphatidylinositol-3-kinase-independent manner. PubMed: Wound healing efficacy of Jatyadi Taila: in vivo evaluation in rat using excision wound model. PubMed: Gastroprotective Properties of Karanjin from Karanja (Pongamia pinnata) Seeds; Role as Antioxidant and H, K-ATPase Inhibitor. PubMed: A new biflavonyloxymethane from Pongamia pinnata. PubMed: A new chalcone from Pongamia pinnata and its antioxidant properties. PubMed: Identification of pongamol and karanjin as lead compounds with antihyperglycemic activity from Pongamia pinnata fruits. PubMed: [Two new flavones from Fordia cauliflora of Yunnan]. PubMed: Synthesis of novel benzofuran isoxazolines as protein tyrosine phosphatase 1B inhibitors. PubMed: Synthesis of 4-hydroxy-1-methylindole and benzo[b]thiophen-4-ol based unnatural flavonoids as new class of antimicrobial agents. PubMed: [Study on flavonoids from stem bark of Pongamia pinnata]. PubMed: Structure and biological activity of a new rotenoid from Pongamia pinnata. PubMed: Suppression of nitrification and N2O emission by karanjin--a nitrification inhibitor prepared from karanja (Pongamia glabra Vent.). PubMed: Flavonoids from Lonchocarpus latifolius roots. PubMed: Hypoglycemic action of karanjin. PubMed: Experiments on the synthesis of karanjin.