nictoflorin
kaempferol-3-O-beta-rutinoside
Identification
| Name | nictoflorin |
| IUPAC | 5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one |
| CAS Number | 17650-84-9 |
| FDA UNII | 4056D20K3H |
| Molecular Formula | C27 H30 O15 |
| Molecular Weight | 594.52410000 |
| MDL Number | MFCD03427292 |
| Nikkaji Number | J254.147E |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Flash Point | 32.00 °F. TCC ( 0.00 °C. ) (est) |
| Soluble in | water, 2285 mg/L @ 25 °C (est) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | antioxidants |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for nictoflorin usage levels up to | not for fragrance use. |
| Recommendation for nictoflorin flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
4H-1-
benzopyran-4-one, 3-((6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-
5,7-
dihydroxy-2-(4-hydroxyphenyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one
kaempferol 3-O-rutinose
kaempferol-3-O-beta-rutinoside
kaempferol-3-O-rutinoside
PubMed:
In-time and in-space tandem mass spectrometry to determine the metabolic profiling of flavonoids in a typical sweet cherry (Prunus avium L.) cultivar from Southern Italy.
PubMed:
[Study of screening nephroprotective bioactive substances based on triple-color fluorescence probes in Carthami flos].
PubMed:
A systematic study on the influence of the main ingredients of an ivy leaves dry extract on the β2-adrenergic responsiveness of human airway smooth muscle cells.
PubMed:
A new acylated flavonoid tetraglycoside with anti-inflammatory activity from Tipuana tipu leaves.
PubMed:
Quality evaluation of Carthami Flos by HPLC-UV.
PubMed:
Stress-responsive hydroxycinnamate glycosyltransferase modulates phenylpropanoid metabolism in Populus.
PubMed:
Chemical composition and bioactivities of flavonoids-rich extract from Davallia cylindrica Ching.
PubMed:
Antiangiogenic activity of flavonoids from Melia azedarach.
PubMed:
Antinociceptive and anti-inflammatory activities of extract and two isolated flavonoids of Carthamus tinctorius L.
PubMed:
Metabolomic analysis of the polyphenols in germinating mung beans (Vigna radiata) seeds and sprouts.
PubMed:
Bioactive components from flowers of Sambucus nigra L. increase glucose uptake in primary porcine myotube cultures and reduce fat accumulation in Caenorhabditis elegans.
PubMed:
Flavonoids with acetylated branched glycans and bioactivity of Tipuana tipu (Benth.) Kuntze leaf extract.
PubMed:
Flavonoids with α-glucosidase inhibitory activities and their contents in the leaves of Morus atropurpurea.
PubMed:
Linkage mapping, molecular cloning and functional analysis of soybean gene Fg2 encoding flavonol 3-O-glucoside (1 â 6) rhamnosyltransferase.
PubMed:
Two new saponins from tetraploid jiaogulan (Gynostemma pentaphyllum), and their anti-inflammatory and α-glucosidase inhibitory activities.
PubMed:
Extraction, gas chromatography-mass spectrometry analysis and screening of fruits of Terminalia chebula Retz. for its antimicrobial potential.
PubMed:
Developmental effects on phenolic, flavonol, anthocyanin, and carotenoid metabolites and gene expression in potatoes.
PubMed:
Metabolomic profiling and sensorial quality of 'Golden Delicious', 'Liberty', 'Santana', and 'Topaz' apples grown using organic and integrated production systems.
PubMed:
Light gazpachos contain higher phytochemical levels than conventional gazpachos.
PubMed:
Cytotoxic evaluation of Melia azedarach in comparison with, Azadirachta indica and its phytochemical investigation.
PubMed:
Phytochemical composition of Potentilla anserina L. analyzed by an integrative GC-MS and LC-MS metabolomics platform.
PubMed:
Hypoglycemic and anti-hyperglycemic study of Gynura procumbens leaf extracts.
PubMed:
A new ent-kaurane diterpenoid glycoside from Isodon japonica var. glaucocalyx.
PubMed:
The influence of Bauhinia forficata Link subsp. pruinosa tea on lipid peroxidation and non-protein SH groups in human erythrocytes exposed to high glucose concentrations.
PubMed:
Neuroprotective effect of kaempferol glycosides against brain injury and neuroinflammation by inhibiting the activation of NF-κB and STAT3 in transient focal stroke.
PubMed:
Yeast α-glucosidase inhibitory phenolic compounds isolated from Gynura medica leaf.
PubMed:
Simultaneous quantification and validation of caffeoylquinic acids and flavonoids in Hemistepta lyrata and peroxynitrite-scavenging activity.
PubMed:
An optimized method for analysis of phenolic compounds in buds, leaves, and fruits of black currant ( Ribes nigrum L.).
PubMed:
On line characterization of 58 phenolic compounds in Citrus fruit juices from Spanish cultivars by high-performance liquid chromatography with photodiode-array detection coupled to electrospray ionization triple quadrupole mass spectrometry.
PubMed:
Quality control and analytical test method for Taxus baccata tincture preparation.
PubMed:
Nicotiflorin, rutin and chlorogenic acid: phenylpropanoids involved differently in quantitative resistance of potato tubers to biotrophic and necrotrophic pathogens.
PubMed:
[Study on flavonoid chemical constituents contained in Memorialis hirta].
PubMed:
Synthesis and antiglycation activity of kaempferol-3-O-rutinoside (nicotiflorin).
PubMed:
Antihyperlipidemic components of Cassia auriculata aerial parts: identification through in vitro studies.
PubMed:
Gastroprotective effect of Byrsonima sericea DC leaf extract against ethanol-induced gastric injury and its possible mechanisms of action.
PubMed:
Characterization of phenolic compounds in flowers of wild medicinal plants from Northeastern Portugal.
PubMed:
Stability of the phenolic and carotenoid profile of gazpachos during storage.
PubMed:
New acylated anthocyanins and other flavonoids from the red flowers of Clematis cultivars.
PubMed:
Potent antiviral flavone glycosides from Ficus benjamina leaves.
PubMed:
Phenolic composition and antioxidant activity of aqueous infusions from Capparis spinosa L. and Crithmum maritimum L. before and after submission to a two-step in vitro digestion model.
PubMed:
Antioxidant flavonol glycosides from Elaeocarpus serratus and Filicium decipiens.
PubMed:
Bioactivities of Chuquiraga straminea sandwith.
PubMed:
A new hepatoprotective flavone glycoside from the flowers of Onopordum alexandrinum growing in Egypt.
PubMed:
[Study on chemical constituents from leaves of Naudea officinalis].
PubMed:
Isolation and identification of phenolic compounds from Gynura divaricata leaves.
PubMed:
[Aromatic constituents of Heteroplexis micocephal and their bioactivities].
PubMed:
A-glucosidase inhibitory activity of kaempferol-3-O-rutinoside.
PubMed:
Production of flavonoids in organogenic cultures of Alpinia zerumbet.
PubMed:
Sap phytochemical compositions of some bananas in Thailand.
PubMed:
Extracts from the Mongolian traditional medicinal plants Dianthus versicolorFisch. and Lilium pumilum Delile stimulate bile flow in an isolated perfused rat liver model.
PubMed:
Flavonoids from the stems of Croton caudatus Geisel. var. tomentosus Hook.
PubMed:
Identification of bioactive compounds from flowers of black elder (Sambucus nigra L.) that activate the human peroxisome proliferator-activated receptor (PPAR) gamma.
PubMed:
Flavonoid glycosides from the leaves of Cissus ibuensis hook (vitaceae).
PubMed:
Simultaneous determination of phenolic acids and flavonoids in Lycium barbarum Linnaeus by HPLC-DAD-ESI-MS.
PubMed:
[Quality evaluation of Flos Carthami].
PubMed:
Rhusonoside A, a new megastigmane glycoside from Rhus sylvestris, increases the function of osteoblastic MC3T3-E1 cells.
PubMed:
Tronchuda cabbage (Brassica oleracea L. var. costata DC): scavenger of reactive nitrogen species.
PubMed:
Flavonoids with iNOS inhibitory activity from Pogonatherum crinitum.
PubMed:
Quali-quantitative analyses of Flavonoids of Morus nigra L. and Morus alba L. (Moraceae) fruits.
PubMed:
[Glycosides from flowers of Jasminum officinale L. var. grandiflorum].
PubMed:
Effect of Ginkgo biloba extract on oxidative metabolism of valproic acid in hepatic microsomes from donors with the CYP2C9*1/*1 genotype.
PubMed:
Reactive oxygen species scavenging activity of flavone glycosides from Melilotus neapolitana.
PubMed:
Phenolic profile of Cydonia oblonga Miller leaves.
PubMed:
Chemical constituents from leaves of Celastrus gemmatus Loes.
PubMed:
Platelet-activating factor (PAF) receptor binding antagonist activity of the methanol extracts and isolated flavonoids from Chromolaena odorata (L.) King and Robinson.
PubMed:
Experimental design for extraction and quantification of phenolic compounds and organic acids in white "Vinho Verde" grapes.
PubMed:
In vitro peroxynitrite scavenging activity of 6-hydroxykynurenic acid and other flavonoids from Gingko biloba yellow leaves.
PubMed:
Elemanolide sesquiterpenes and eudesmane sesquiterpene glycosides from Centaurea hierapolitana.
PubMed:
Antioxidant compounds from Ebenus pinnata.
PubMed:
Cytotoxic C-benzylated chalcone and other constituents of Ellipeiopsis cherrevensis.
PubMed:
Determination of flavonoids and phenolics and their distribution in almonds.
PubMed:
Antioxidant polyphenols in almond and its coproducts.
PubMed:
Effect of Ginkgo biloba extract on procarcinogen-bioactivating human CYP1 enzymes: identification of isorhamnetin, kaempferol, and quercetin as potent inhibitors of CYP1B1.
PubMed:
Topical anti-inflammatory activity of Solenostemma argel leaves.
PubMed:
[Applications of two-dimensional liquid chromatography coupled to mass spectrometry for the separation and identification of compounds in ginkgo biloba extracts].
PubMed:
Phenylpropanoids, phenylalanine ammonia lyase and peroxidases in elicitor-challenged cassava (Manihot esculenta) suspension cells and leaves.
PubMed:
Bioguided isolation and identification of the nonvolatile antioxidant compounds from fennel (Foeniculum vulgare Mill.) waste.
PubMed:
Phytochemical constituents of the aerial parts from Solidago virga-aurea var. gigantea.
PubMed:
Phytochemical constituents from Diodia teres.
PubMed:
Metabolite profiling of tomato (Lycopersicon esculentum) using 1H NMR spectroscopy as a tool to detect potential unintended effects following a genetic modification.
PubMed:
Characterization and content of flavonoid glycosides in genetically modified tomato (Lycopersicon esculentum) fruits.
PubMed:
Study of the collision-induced radical cleavage of flavonoid glycosides using negative electrospray ionization tandem quadrupole mass spectrometry.
PubMed:
Difference in flavonoid and isoflavone profile between soybean and soy leaf.
PubMed:
[Studies on chemical components of Carthamus tinctorius petals].
PubMed:
Inhibition of nitric oxide synthase expression by a methanolic extract of Crescentia alata and its derived flavonols.
PubMed:
Flavonoids and phenylpropanoid derivatives from Campanula barbata.
PubMed:
New jujubogenin glycosides from Colubrina asiatica.
PubMed:
Antimicrobial constituents of the leaves of Acalypha wilkesiana and Aacalypha hispida.
PubMed:
Triterpene saponins from Randia formosa.
PubMed:
Flavonoids from Goodyera schlechtendaliana.
PubMed:
Antimicrobial activity of Mitracarpus scaber extract and isolated constituents.
PubMed:
Antioxidant properties of flavonol glycosides from green beans.
PubMed:
Flavonol glycosides from cassia hirsuta
PubMed:
Antibacterial and chemical evaluation of Chromolaena moritziana.
PubMed:
Identification and quantitative analysis of phenolic compounds from the dry extract of Hedera helix.
PubMed:
Cyanogenic and non-cyanogenic glycosides from Manihot esculenta.
PubMed:
Saponins from leaves of Acanthopanax sieboldianus.
PubMed:
Karsoside and scropolioside D, two new iridoid glycosides from Scrophularia ilwensis.
PubMed:
[Glycosides of phenolic acid and flavonoids from the leaves of Glycyrrhiza uralensis Ficsh].
PubMed:
[Flavonoids in the flowers of Primula officinalis].