herbacetin
8-hydroxykaempferol
Identification
| Name | herbacetin |
| IUPAC | 3,5,7,8-tetrahydroxy-2-(4-hydroxyphenyl)chromen-4-one |
| CAS Number | 527-95-7 |
| FDA UNII | Search |
| Molecular Formula | C15 H10 O7 |
| Molecular Weight | 302.23910000 |
| MDL Number | MFCD00210585 |
| Nikkaji Number | J11.871K |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 618.70 °C. @ 760.00 mm Hg (est) |
| Flash Point | 462.00 °F. TCC ( 239.00 °C. ) (est) |
| logP (o/w) | 1.140 (est) |
| Soluble in | water, 2472 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural food |
| Recommendation for herbacetin usage levels up to | not for fragrance use. |
| Recommendation for herbacetin flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
4H-1-
benzopyran-4-one, 3,5,7,8-tetrahydroxy-2-(4-hydroxyphenyl)-
8-
hydroxykaempferol
3,5,7,8-
tetrahydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one
3,5,7,8-
tetrahydroxy-2-(4-hydroxyphenyl)chromen-4-one
PubMed:
Application and recovery of ionic liquids in the preparative separation of four flavonoids from Rhodiola rosea by on-line three-dimensional liquid chromatography.
PubMed:
Microwave-assisted extraction of herbacetin diglucoside from flax (Linum usitatissimum L.) seed cakes and its quantification using an RP-HPLC-UV system.
PubMed:
Herbacetin, a constituent of ephedrae herba, suppresses the HGF-induced motility of human breast cancer MDA-MB-231 cells by inhibiting c-Met and Akt phosphorylation.
PubMed:
Separation of four flavonoids from Rhodiola rosea by on-line combination of sample preparation and counter-current chromatography.
PubMed:
LC-NMR, NMR, and LC-MS identification and LC-DAD quantification of flavonoids and ellagic acid derivatives in Drosera peltata.
PubMed:
Characterization of phenolic constituents from ephedra herb extract.
PubMed:
Herbacetin induces apoptosis in HepG2 cells: Involvements of ROS and PI3K/Akt pathway.
PubMed:
The antioxidant and anti-inflammatory effects of phenolic compounds isolated from the root of Rhodiola sachalinensis A. BOR.
PubMed:
[Studies on the chemical constituents of Rhodiola rosea].
PubMed:
The chain length of lignan macromolecule from flaxseed hulls is determined by the incorporation of coumaric acid glucosides and ferulic acid glucosides.
PubMed:
Calpain inhibitory flavonoids isolated from Orostachys japonicus.
PubMed:
Microbial metabolism of biologically active secondary metabolites from Nerium oleander L.
PubMed:
Flavonol glucuronides and C-glucosidic ellagitannins from Melaleuca squarrosa.
PubMed:
seco-Cycloartane triterpenes from Gardenia aubryi.
PubMed:
The flavonoid herbacetin diglucoside as a constituent of the lignan macromolecule from flaxseed hulls.
PubMed:
[Studies on the chemical constituents of Rhodiola dumulosa (II)].
PubMed:
[Studies on the chemical constituents from Rhodiola dumulosa (I)].
PubMed:
Electrospray mass spectrometric decomposition of some glucuronic acid-containing flavonoid diglycosides.
PubMed:
New erythroxane-type diterpenoids from Fagonia boveana (Hadidi) Hadidi & Graf.
PubMed:
Antioxidative phenolic compounds from the roots of Rhodiola sachalinensis A. Bor.
PubMed:
[Studies on the chemical constituents of Rhodiola fastigita].
PubMed:
Flavan-3-ols and flavonoids from Potentilla anserina.