ginsenoside Rf
Identification
| Name | ginsenoside Rf |
| CAS Number | 52286-58-5 |
| FDA UNII | JOS8BON5YW |
| Molecular Formula | C42 H72 O14 |
| Molecular Weight | 801.02464000 |
| MDL Number | MFCD00210509 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 921.00 °C. @ 760.00 mm Hg (est) |
| Flash Point | 951.00 °F. TCC ( 510.80 °C. ) (est) |
| logP (o/w) | 3.560 (est) |
| Soluble in | water, 0.1125 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | intraperitoneal-mouse LD50 1340 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for ginsenoside Rf usage levels up to | not for fragrance use. |
| Recommendation for ginsenoside Rf flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
ginsenoside RF
panaxoside Rf
panaxoside RF
PubMed:
Discrimination of white ginseng origins using multivariate statistical analysis of data sets.
PubMed:
Detoxifying effect of fermented black ginseng on H2O2-induced oxidative stress in HepG2 cells.
PubMed:
[Determination of twelve active compounds in Qili Qiangxin capsules by UPLC-MS].
PubMed:
Metabolomic approach for discrimination of processed ginseng genus (Panax ginseng and Panax quinquefolius) using UPLC-QTOF MS.
PubMed:
Efficacy comparison of Korean ginseng and American ginseng on body temperature and metabolic parameters.
PubMed:
[Chemical constituents from roots and rhizomes of Panax ginseng cultivated in Jilin province].
PubMed:
Induction of G2/M phase cell cycle arrest and apoptosis by ginsenoside Rf in human osteosarcoma MGâ63 cells through the mitochondrial pathway.
PubMed:
Production of aglycone protopanaxatriol from ginseng root extract using Dictyoglomus turgidum β-glycosidase that specifically hydrolyzes the xylose at the C-6 position and the glucose in protopanaxatriol-type ginsenosides.
PubMed:
Updating chemical profiling of red ginseng via the elucidation of two geometric isomers of ginsenosides Rg9 and Rg10.
PubMed:
Ginsenjilinol, a new protopanaxatriol-type saponin with inhibitory activity on LPS-activated NO production in macrophage RAW 264.7 cells from the roots and rhizomes of Panax ginseng.
PubMed:
Effects of ginsenoside on pacemaker potentials of cultured interstitial cells of Cajal clusters from the small intestine of mice.
PubMed:
Induction of CYP3A4 and MDR1 gene expression by baicalin, baicalein, chlorogenic acid, and ginsenoside Rf through constitutive androstane receptor- and pregnane X receptor-mediated pathways.
PubMed:
Mass spectrometric imaging of ginsenosides localization in Panax ginseng root.
PubMed:
Rapid qualitative and quantitative analyses of Asian ginseng in adulterated American ginseng preparations by UPLC/Q-TOF-MS.
PubMed:
Microbial conversion of rare ginsenoside Rf to 20(S)-protopanaxatriol by Aspergillus niger.
PubMed:
On-line concentration of neutral analytes by complexation and acetonitrile sweeping in nonionic microemulsion electrokinetic chromatography with direct ultraviolet detection.
PubMed:
Biotransformation of ginsenoside Rf to Rh1 by recombinant beta-glucosidase.
PubMed:
Direct on-line analysis of neutral analytes by dual sweeping via complexation and organic solvent field enhancement in nonionic MEKC.
PubMed:
[A quantitative method using one marker for simultaneous assay of ginsenosides in Panax ginseng and P. notoginseng].
PubMed:
Pressure and electrokinetic injections for on-line sample stacking neutral analytes in microemulsion electrokinetic chromatography with salt-containing matrixes.
PubMed:
Ultra-performance LC/TOF MS analysis of medicinal Panax herbs for metabolomic research.
PubMed:
Neuroprotective effects of ginseng saponins against L-type Ca2+ channel-mediated cell death in rat cortical neurons.
PubMed:
Retention behavior of ginsenosides on a poly(vinyl alcohol)-bonded stationary phase in hydrophilic interaction chromatography.
PubMed:
Inhibitory effects of Korean red ginseng and its genuine constituents ginsenosides Rg3, Rf, and Rh2 in mouse passive cutaneous anaphylaxis reaction and contact dermatitis models.
PubMed:
Ginsenoside Rf, a component of ginseng, regulates lipoprotein metabolism through peroxisome proliferator-activated receptor alpha.
PubMed:
Modulating effect of ginseng saponins on heterologously expressed HERG currents in Xenopus oocytes.
PubMed:
[Study on the chemical constituents of the roots of commercial ginseng].
PubMed:
Phytochemistry of wild populations of Panax quinquefolius L. (North American ginseng).
PubMed:
Effects of ginsenosides on glycine receptor alpha1 channels expressed in Xenopus oocytes.
PubMed:
[Practical optimization of the two-dimensional thin-layer chromatographic separation of ginsenosides].
PubMed:
Ginsenoside Rf potentiates U-50,488H-induced analgesia and inhibits tolerance to its analgesia in mice.
PubMed:
Functional expression of a novel ginsenoside Rf binding protein from rat brain mRNA in Xenopus laevis oocytes.
PubMed:
The antimetastatic and immunomodulating activities of ginseng minor glycosides.
PubMed:
Effects of ginsenosides from Panax ginseng on cell-to-cell communication function mediated by gap junctions.
PubMed:
Use of high-performance liquid chromatography-tandem mass spectrometry to distinguish Panax ginseng C. A. Meyer (Asian ginseng) and Panax quinquefolius L. (North American ginseng).
PubMed:
Preparation of monoclonal antibody against ginsenoside Rf and its enzyme immunoassay.
PubMed:
Differentiation and authentication of Panax ginseng, Panax quinquefolius, and ginseng products by using HPLC/MS.
PubMed:
Effects of ginseng components on c-DNA-expressed cytochrome P450 enzyme catalytic activity.
PubMed:
Ginsenoside Rf2, a new dammarane glycoside from Korean red ginseng (Panax ginseng).
PubMed:
Determination of ginsenoside Rf and Rg2 from Panax ginseng using enzyme immunoassay.
PubMed:
Ginsenoside Rf, a trace component of ginseng root, produces antinociception in mice.
PubMed:
A trace component of ginseng that inhibits Ca2+ channels through a pertussis toxin-sensitive G protein.
PubMed:
Saponins from Vietnamese Ginseng, Panax vietnamensis HA et Grushv. Collected in central Vietnam. II.
PubMed:
[Suppression of lipid peroxidation by sho-saiko-to and its components in rat liver subcellular membranes].
PubMed:
[Isolation and identification of saponin IV, V, VI and VII in ginseng stems].