eupatorin-5-methyl ether

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flavone, 3'-hydroxy-4',5,6,7-tetramethoxy-

CAS: 21764-09-0 C19 H18 O7 MW: 358.34686000
All Ingredients Aromatic Ingredients CAS Numbers Found in Nature

Identification

Nameeupatorin-5-methyl ether
IUPAC2-(3-hydroxy-4-methoxyphenyl)-5,6,7-trimethoxychromen-4-one
CAS Number21764-09-0
FDA UNIISearch
Molecular FormulaC19 H18 O7
Molecular Weight358.34686000
MDL NumberMFCD00016928
Nikkaji NumberJ428.538G

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 573.70 °C. @ 760.00 mm Hg (est)
Flash Point 405.00 °F. TCC ( 207.40 °C. ) (est)
logP (o/w) 3.210 (est)
Soluble in water, 52.82 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for eupatorin-5-methyl ether usage levels up tonot for fragrance use.
Recommendation for eupatorin-5-methyl ether flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

found in nature

Synonyms

4H-1- benzopyran-4-one, 2-(3-hydroxy-4-methoxyphenyl)-5,6,7-trimethoxy- eupatorin-5-methylether flavone, 3'-hydroxy-4',5,6,7-tetramethoxy- 2-(3- hydroxy-4-methoxyphenyl)-5,6,7-trimethoxychromen-4-one PubMed: Benzo[a]pyrene sensitizes MCF7 breast cancer cells to induction of G1 arrest by the natural flavonoid eupatorin-5-methyl ether, via activation of cell signaling proteins and CYP1-mediated metabolism. PubMed: Flavonoids eupatorin and sinensetin present in Orthosiphon stamineus leaves inhibit inflammatory gene expression and STAT1 activation. PubMed: Comparative CYP1A1 and CYP1B1 substrate and inhibitor profile of dietary flavonoids.