dhurrin

benzeneacetonitrile, alpha-(beta-D-glucopyranosyloxy)-4-hydroxy-, (alphaS)- (S)-(beta-D- glucopyranosyloxy)(4-hydroxyphenyl)acetonitrile (S)-p- hydroxymandelnitrile-beta-D-glucopyranoside (2S)-2-(4- hydroxyphenyl)-2-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyacetonitrile PubMed: The necrotrophic effector protein SnTox3 re-programs metabolism and elicits a strong defence response in susceptible wheat leaves. PubMed: Age versus stage: does ontogeny modify the effect of phosphorus and arbuscular mycorrhizas on above- and below-ground defence in forage sorghum? PubMed: Effects of PEG-induced osmotic stress on growth and dhurrin levels of forage sorghum. PubMed: High basal defense gene expression determines sorghum resistance to the whorl-feeding insect southwestern corn borer. PubMed: Amygdalin analogues inhibit IFN-γ signalling and reduce the inflammatory response in human epidermal keratinocytes. PubMed: Forward genetics by genome sequencing reveals that rapid cyanide release deters insect herbivory of Sorghum bicolor. PubMed: Amphipol trapping of a functional CYP system. PubMed: The rare cyanogen proteacin, and dhurrin, from foliage of Polyscias australiana, a tropical Araliaceae. PubMed: Visualizing metabolite distribution and enzymatic conversion in plant tissues by desorption electrospray ionization mass spectrometry imaging. PubMed: Sorghum allelopathy--from ecosystem to molecule. PubMed: Global transcriptome analysis reveals distinct expression among duplicated genes during sorghum-interaction. PubMed: Drying and processing protocols affect the quantification of cyanogenic glucosides in forage sorghum. PubMed: Turning the 'mustard oil bomb' into a 'cyanide bomb': aromatic glucosinolate metabolism in a specialist insect herbivore. PubMed: A combined biochemical screen and TILLING approach identifies mutations in Sorghum bicolor L. Moench resulting in acyanogenic forage production. PubMed: A simple analytical method for dhurrin content evaluation in cyanogenic plants for their utilization in fodder and biofumigation. PubMed: Homology modeling of the three membrane proteins of the dhurrin metabolon: catalytic sites, membrane surface association and protein-protein interactions. PubMed: Comparison of gas chromotography, spectrophotometry and near infrared spectroscopy to quantify prussic acid potential in forages. PubMed: Plant science. Dynamic metabolons. PubMed: Primary or secondary? Versatile nitrilases in plant metabolism. PubMed: Evolution of heteromeric nitrilase complexes in Poaceae with new functions in nitrile metabolism. PubMed: Metabolon formation in dhurrin biosynthesis. PubMed: Rate of hydrolysis and degradation of the cyanogenic glycoside - dhurrin - in soil. PubMed: Consequences of transferring three sorghum genes for secondary metabolite (cyanogenic glucoside) biosynthesis to grapevine hairy roots. PubMed: Reconstitution of cyanogenesis in barley (Hordeum vulgare L.) and its implications for resistance against the barley powdery mildew fungus. PubMed: Determination of catalytic key amino acids and UDP sugar donor specificity of the cyanohydrin glycosyltransferase UGT85B1 from Sorghum bicolor. Molecular modeling substantiated by site-specific mutagenesis and biochemical analyses. PubMed: Cyanogenic glycosides and menisdaurin from Guazuma ulmifolia, Ostrya virgininana, Tiquilia plicata and Tiquilia canescens. PubMed: Tailoring the plant metabolome without a loose stitch. PubMed: Predictive metabolic engineering in plants: still full of surprises. PubMed: Metabolic channeling in plants. PubMed: Metabolic engineering of dhurrin in transgenic Arabidopsis plants with marginal inadvertent effects on the metabolome and transcriptome. PubMed: Structural determinants of substrate specificity in family 1 beta-glucosidases: novel insights from the crystal structure of sorghum dhurrinase-1, a plant beta-glucosidase with strict specificity, in complex with its natural substrate. PubMed: Raman spectroscopic analysis of cyanogenic glucosides in plants: development of a flow injection surface-enhanced Raman scatter (FI-SERS) method for determination of cyanide. PubMed: The in vitro substrate regiospecificity of recombinant UGT85B1, the cyanohydrin glucosyltransferase from Sorghum bicolor. PubMed: Mutational and structural analysis of aglycone specificity in maize and sorghum beta-glucosidases. PubMed: Dhurrin synthesis in sorghum is regulated at the transcriptional level and induced by nitrogen fertilization in older plants. PubMed: Relationship Between Levels of Cyanide in Sudangrass Hybrids Incorporated into Soil and Suppression of Meloidogyne hapla. PubMed: Characterization of transgenic Arabidopsis thaliana with metabolically engineered high levels of p-hydroxybenzylglucosinolate. PubMed: Resistance to an herbivore through engineered cyanogenic glucoside synthesis. PubMed: Metabolism of tyrosine and tryptophan--new genes for old pathways. PubMed: The mechanism of substrate (aglycone) specificity in beta -glucosidases is revealed by crystal structures of mutant maize beta -glucosidase-DIMBOA, -DIMBOAGlc, and -dhurrin complexes. PubMed: Transgenic tobacco and Arabidopsis plants expressing the two multifunctional sorghum cytochrome P450 enzymes, CYP79A1 and CYP71E1, are cyanogenic and accumulate metabolites derived from intermediates in Dhurrin biosynthesis. PubMed: The aglycone specificity-determining sites are different in 2, 4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA)-glucosidase (Maize beta -glucosidase) and dhurrinase (Sorghum beta -glucosidase). PubMed: Metabolic engineering of p-hydroxybenzylglucosinolate in Arabidopsis by expression of the cyanogenic CYP79A1 from Sorghum bicolor. PubMed: The UDP-glucose:p-hydroxymandelonitrile-O-glucosyltransferase that catalyzes the last step in synthesis of the cyanogenic glucoside dhurrin in Sorghum bicolor. Isolation, cloning, heterologous expression, and substrate specificity. PubMed: Production and properties of the linamarase and amygdalase activities of Penicillium aurantiogriseum P35. PubMed: Substrate specificity of the cytochrome P450 enzymes CYP79A1 and CYP71E1 involved in the biosynthesis of the cyanogenic glucoside dhurrin in Sorghum bicolor (L.) Moench. PubMed: The presence of CYP79 homologues in glucosinolate-producing plants shows evolutionary conservation of the enzymes in the conversion of amino acid to aldoxime in the biosynthesis of cyanogenic glucosides and glucosinolates. PubMed: Cloning of three A-type cytochromes P450, CYP71E1, CYP98, and CYP99 from Sorghum bicolor (L.) Moench by a PCR approach and identification by expression in Escherichia coli of CYP71E1 as a multifunctional cytochrome P450 in the biosynthesis of the cyanogenic glucoside dhurrin. PubMed: Isolation and reconstitution of cytochrome P450ox and in vitro reconstitution of the entire biosynthetic pathway of the cyanogenic glucoside dhurrin from sorghum. PubMed: Dhurrin-6'-glucoside, a cyanogenic diglucoside from Sorghum bicolor. PubMed: The primary sequence of cytochrome P450tyr, the multifunctional N-hydroxylase catalyzing the conversion of L-tyrosine to p-hydroxyphenylacetaldehyde oxime in the biosynthesis of the cyanogenic glucoside dhurrin in Sorghum bicolor (L.) Moench. PubMed: Purification and characterization of recombinant cytochrome P450TYR expressed at high levels in Escherichia coli. PubMed: Cytochrome P-450TYR is a multifunctional heme-thiolate enzyme catalyzing the conversion of L-tyrosine to p-hydroxyphenylacetaldehyde oxime in the biosynthesis of the cyanogenic glucoside dhurrin in Sorghum bicolor (L.) Moench. PubMed: Characterization of cytochrome P450TYR, a multifunctional haem-thiolate N-hydroxylase involved in the biosynthesis of the cyanogenic glucoside dhurrin. PubMed: Isolation of the heme-thiolate enzyme cytochrome P-450TYR, which catalyzes the committed step in the biosynthesis of the cyanogenic glucoside dhurrin in Sorghum bicolor (L.) Moench. PubMed: Molecular cloning of hydroxynitrile lyase from Sorghum bicolor (L.). Homologies to serine carboxypeptidases. PubMed: The metabolism of a natural product: lessons learned from cyanogenic glycosides. PubMed: Involvement of Cytochrome P-450 in the Biosynthesis of Dhurrin in Sorghum bicolor (L.) Moench. PubMed: 2-nitro-3-(p-hydroxyphenyl)propionate and aci-1-nitro-2-(p-hydroxyphenyl)ethane, two intermediates in the biosynthesis of the cyanogenic glucoside dhurrin in Sorghum bicolor (L.) Moench. PubMed: The biosynthesis of cyanogenic glucosides in higher plants. Identification of three hydroxylation steps in the biosynthesis of dhurrin in Sorghum bicolor (L.) Moench and the involvement of 1-ACI-nitro-2-(p-hydroxyphenyl)ethane as an intermediate. PubMed: Turnover of dhurrin in green sorghum seedlings. PubMed: Larvicidal effects of grain sorghum (Sorghum bicolor) seedling extracts upon Culex pipiens larvae. PubMed: The biosynthesis of cyanogenic glucosides in higher plants. The (E)- and (Z)-isomers of p-hydroxyphenylacetaldehyde oxime as intermediates in the biosynthesis of dhurrin in Sorghum bicolor (L.) Moench. PubMed: Biosynthesis of the Cyanogenic Glucoside Dhurrin in Seedlings of Sorghum bicolor (L.) Moench and Partial Purification of the Enzyme System Involved. PubMed: Allelopathic potential of sorghum-sudangrass hybrid (sudex). PubMed: Cyanogenic glucosides: the biosynthetic pathway and the enzyme system involved. PubMed: Characterization of beta-glucosidases with high specificity for the cyanogenic glucoside dhurrin in Sorghum bicolor (L.) moench seedlings. PubMed: Relationship between contents of leucoanthocyanidin and dhurrin in sorghum leaves. PubMed: Hydrolysis of a naturally occurring beta-glucoside by a broad-specificity beta-glucosidase from liver. PubMed: In-vitro biosynthesis of 1-(4'-hydroxyphenyl)-2-nitroethane and production of cyanogenic compounds in osmotically stressed cell suspension cultures of Eschscholtzia californica Cham. PubMed: Leakage of Dhurrin and p-Hydroxybenzaldehyde from Young Sorghum Shoots Immersed in Various Solvents. PubMed: [The occurrence of hydrocyanic acid in Cormophytes. 18th. Communication. New observations in leguminosae-Papilionoideae (Galegeae, Genisteae, Loteae, Phaseoleae)]. PubMed: Subcellular Localization of Dhurrin beta-Glucosidase and Hydroxynitrile Lyase in the Mesophyll Cells of Sorghum Leaf Blades. PubMed: Aphid feeding deterrents in sorghum : Bioassay isolation and characterization. PubMed: [The cyanogenic glycosides of triticum, secale and sorghum]. PubMed: The biosynthesis of cyanogenic glucosides in higher plants. Channeling of intermediates in dhurrin biosynthesis by a microsomal system from Sorghum bicolor (linn) Moench. PubMed: The biosynthesis of cyanogenic glucosides in higher plants. N-Hydroxytyrosine as an intermediate in the biosynthesis of dhurrin by Sorghum bicolor (Linn) Moench. PubMed: Tissue Distributions of Dhurrin and of Enzymes Involved in Its Metabolism in Leaves of Sorghum bicolor. PubMed: Presence of the cyanogenic glucoside dhurrin in isolated vacuoles from sorghum. PubMed: Localization of Cinnamic Acid 4-Monooxygenase and the Membrane-bound Enzyme System for Dhurrin Biosynthesis in Sorghum Seedlings. PubMed: Subcellular localization of the cyanogenic glucoside of sorghum by autoradiography. PubMed: Stereochemical aspects of the biosynthesis of the epimeric cyanogenic glucosides dhurrin and taxiphyllin. PubMed: The in vitro biosynthesis of dhurrin, the cyanogenic glycoside of Sorghum bicolor. PubMed: Biosynthesis of phenolic compounds in first internodes of sorghum: lignin and related products. PubMed: The metabolism of aromatic compounds in higher plants. VII. The origin of the nitrile nitrogen atom of dhurrin (beta-D-glucopyranosyloxy-L-p-hydroxymandelonitrile). PubMed: The metabolism of aromatic compounds in higher plants. VI. Studies on the biosynthesis of dhurrin, the cyanogenic glucoside of Sorghum vulgare.