cupressuflavone
4',4''',5,5'',7,7''-hexahydroxy-8-8''-biflavone
Identification
| Name | cupressuflavone |
| IUPAC | 8-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxochromen-8-yl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one |
| CAS Number | 3952-18-9 |
| FDA UNII | Search |
| Molecular Formula | C30 H18 O10 |
| Molecular Weight | 538.46546000 |
| Nikkaji Number | J22.579G |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 927.00 °C. @ 760.00 mm Hg (est) |
| Flash Point | 597.00 °F. TCC ( 314.00 °C. ) (est) |
| logP (o/w) | 3.070 (est) |
| Soluble in | water, 0.03344 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for cupressuflavone usage levels up to | not for fragrance use. |
| Recommendation for cupressuflavone flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
[8,8'-
bi-4H-1-benzopyran]-4,4'-dione, 5,5',7,7'-tetrahydroxy-2,2'-bis(4-hydroxyphenyl)-
8,8''-
biapigenin
cupressiflavone
8-[5,7-
dihydroxy-2-(4-hydroxyphenyl)-4-oxochromen-8-yl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
4',4''',5,5'',7,7''-
hexahydroxy-8-8''-biflavone
5,5',7,7'-
tetrahydroxy-2,2'-bis(4-hydroxyphenyl)-4H,4'H-8,8'-bichromene-4,4'-dione trihydrate
PubMed:
Protective Role of Cupressuflavone from Cupressus macrocarpa against Carbon Tetrachloride-Induced Hepato- and Nephrotoxicity in Mice.
PubMed:
[Chemical constituents from seeds of Sophora alopecuroides].
PubMed:
Study of the hepatoprotective effect of Juniperus phoenicea constituents.
PubMed:
Structure-activity relationship study of biflavonoids on the Dengue virus polymerase DENV-NS5 RdRp.
PubMed:
Potential neuroprotective flavonoid-based inhibitors of CDK5/p25 from Rhus parviflora.
PubMed:
Biophytum sensitivum: Ancient medicine, modern targets.
PubMed:
Antiviral activity-guided fractionation from Araucaria angustifolia leaves extract.
PubMed:
Free radical scavenging and antielastase activities of flavonoids from the fruits of Thuja orientalis.
PubMed:
Phytochemical investigation and hepatoprotective activity of Cupressus sempervirens L. leaves growing in Egypt.
PubMed:
The chemical composition of Microbiota decussata.
PubMed:
Phytochemical study on American plants I. Two new phenol glucosides, together with known biflavones and diterpene, from leaves of Juniperus occidentalis Hook.
PubMed:
Antifungal biflavones from Cupressocyparis leylandii.
PubMed:
Hinokiflavone, a cytotoxic principle from Rhus succedanea and the cytotoxicity of the related biflavonoids.