sodium cholate

cholic acid, monosodium salt

CAS: 361-09-1 C24 H39 Na O5 MW: 430.56059928

Identification

Namesodium cholate
CAS Number361-09-1
EINECS206-643-5
FDA UNIINU3Y4CCH8Z
Molecular FormulaC24 H39 Na O5
Molecular Weight430.56059928
MDL NumberMFCD00150749

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Flash Point 32.00 °F. TCC ( 0.00 °C. ) (est)
Soluble in water, 3520 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral Toxicityintraperitoneal-mouse LD50 164 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION\nCARDIAC: EKG CHANGES NOT DIAGNOSTIC OF ABOVE\nBEHAVIORAL: COMA']

Safety in Use

Categorypharmaceuticals / chemical synthisis
Recommendation for sodium cholate usage levels up tonot for fragrance use.
Recommendation for sodium cholate flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

cholan-24-oic acid, 3,7,12-trihydroxy-, monosodium salt, (3-alpha,5-beta,7-alpha,12-alpha)- cholan-24-oic acid, 3,7,12-trihydroxy-, monosodium salt, (3alpha,5beta,7alpha,12alpha)- cholan-24-oic acid, 3,7,12-trihydroxy-, sodium salt (1:1), (3alpha,5beta,7alpha,12alpha)- cholic acid, monosodium salt cholic acid, sodium salt sodium cholic acid trihydroxy 3-7-12 cholanate de Na PubMed: Fluorescence method using on-line sodium cholate coacervate surfactant mediated extraction for the flow injections analysis of Rhodamine B. PubMed: Effect of nanostructured lipid vehicles on percutaneous absorption of curcumin. PubMed: Study on interaction of bile salts with curcumin and curcumin embedded in dipalmitoyl-sn-glycero-3-phosphocholine liposome. PubMed: Enzymatic synthesis of phosphatidylserine using bile salt mixed micelles. PubMed: [Analysis of phthalate esters in plastic-packaging bags on-line sample stacking-microemulsion electrokinetic chromatography]. PubMed: Label-free aptamer-based partial filling technique for enantioseparation and determination of DL-tryptophan with micellar electrokinetic chromatography. PubMed: Effect of prolonged refrigeration on the lipid profile, lipase activity, and oxidative status of human milk. PubMed: In vitro hypoglycemic and cholesterol lowering effects of dietary fiber prepared from cocoa (Theobroma cacao L.) shells. PubMed: Fish protein decreases serum cholesterol in rats by inhibition of cholesterol and bile acid absorption. PubMed: Fish protein hydrolysates affect cholesterol metabolism in rats fed non-cholesterol and high-cholesterol diets. PubMed: In vitro binding capacity of bile acids by defatted corn protein hydrolysate. PubMed: In vitro binding capacities of three dietary fibers and their mixture for four toxic elements, cholesterol, and bile acid. PubMed: Determination of phthalate esters in soil by microemulsion electrokinetic chromatography coupled with accelerated solvent extraction. PubMed: Determination of aromatic amines in environmental water sample by hollow fiber-liquid phase microextraction and microemulsion electrokinetic chromatography. PubMed: Probiotic properties of yeasts isolated from chicken feces and kefirs. PubMed: Effects of rice proteins from two cultivars, Koshihikari and Shunyo, on hepatic cholesterol secretion by isolated perfused livers of rats fed cholesterol-enriched diets. PubMed: Blood lipid-lowering and antioxidant effects of a structured lipid containing monoacylglyceride enriched with monounsaturated fatty acids in C57BL/6 mice. PubMed: Separation and detection of isoquinoline alkaloids using MEEKC coupled with field-amplified sample injection induced by ACN. PubMed: A new mixed micellar electrokinetic chromatography method for analysis of natural and synthetic anabolic steroids. PubMed: Effects of cranberry powder on serum lipid profiles and biomarkers of oxidative stress in rats fed an atherogenic diet. PubMed: Microemulsion electrokinetic chromatography coupling with field amplified sample injection and electroosmotic flow suppressant for analysis of some quinolizidine alkaloids. PubMed: Separation and determination of flavonoids using microemulsion EKC with electrochemical detection. PubMed: Determination of flavonoid aglycones in several food samples by mixed micellar electrokinetic chromatography. PubMed: Nonaqueous and aqueous-organic media for the enantiomeric separations of neutral organophosphorus pesticides by CE. PubMed: Evaluation of inactivation methods for severe acute respiratory syndrome coronavirus in noncellular blood products. PubMed: Dietary lectin lowers serum cholesterol and raises fecal neutral sterols in cholesterol-fed rats. PubMed: Functional properties, lipoxygenase activity, and health aspects of Lupinus albus protein isolates. PubMed: Effect of the adaptation to high bile salts concentrations on glycosidic activity, survival at low PH and cross-resistance to bile salts in Bifidobacterium. PubMed: The effect of taurine on cholesterol degradation in mice fed a high-cholesterol diet. PubMed: The effect of taurine on the cholesterol metabolism in rats fed diets supplemented with cholestyramine or high amounts of bile acid. PubMed: The effect of taurine on plasma cholesterol concentration in genetic type 2 diabetic GK rats. PubMed: Mixed micellar electrokinetic capillary chromatography separation of depolymerized grape procyanidins. PubMed: Characterisation of a Bifidobacterium strain with acquired resistance to cholate--a preliminary study. PubMed: Hypocholesterolemic effect of indigestible fraction of Chlorella regularis in cholesterol-fed rats. PubMed: Determination of total cholesterol content in food by flow injection analysis with immobilized cholesterol oxidase enzyme reactor. PubMed: Effects of dietary maritime pine seed oil on lipoprotein metabolism and atherosclerosis development in mice expressing human apolipoprotein B. PubMed: A double antibody sandwich enzyme-linked immunosorbent assay for the detection of Salmonella using biotinylated monoclonal antibodies. PubMed: Cholesterol solubilization in aqueous micellar solutions of quillaja saponin, bile salts, or nonionic surfactants. PubMed: Separation of food grade antioxidants (synthetic and natural) using mixed micellar electrokinetic capillary chromatography. PubMed: A mixture of organisms affects cholesterol metabolism together with rat cecal flora. PubMed: Simultaneous determination of antioxidants, preservatives and sweeteners permitted as additives in food by mixed micellar electrokinetic chromatography. PubMed: Determination of vitamins in food based on supercritical fluid extraction prior to micellar electrokinetic capillary chromatographic analyses of individual vitamins. PubMed: Occurrence of dermatitis in rats fed a cholesterol diet containing field horsetail (Equisetum arvense L.). PubMed: Strain-specific response to hypercholesterolaemic diets in the rat. PubMed: The effects of pH and bile salts on the binding of MeIQx to wheat bran fibre. PubMed: Analysis of macrolide antibiotics by capillary electrophoresis. PubMed: Simultaneous dietary supplementation of sodium cholate and beta-carotene markedly enhances accumulation of beta-carotene in mice. PubMed: In vivo regulation of hepatic lipase activity and mRNA levels by diets which modify cholesterol influx to the liver. PubMed: Relationship between structure and function of dietary fibre: a comparative study of the effects of three galactomannans on cholesterol metabolism in the rat. PubMed: Synthetic low and high fat diets for the study of atherosclerosis in the mouse. PubMed: Purification and characterization of phosphatidate phosphatase from Saccharomyces cerevisiae. PubMed: Effect of dietary taurine on cholesterol 7 alpha-hydroxylase activity in the liver of mice fed a lithogenic diet. PubMed: A mechanism for the hypocholesterolaemic activity of saponins. PubMed: Enzymatic properties of the lipoxygenase from pea seeds. PubMed: Bile production in fasted and fed primates.