negletein
4H-1-benzopyran-4-one, 5,6-dihydroxy-7-methoxy-2-phenyl-
Identification
| Name | negletein |
| IUPAC | 5,6-dihydroxy-7-methoxy-2-phenylchromen-4-one |
| CAS Number | 29550-13-8 |
| FDA UNII | Search |
| Molecular Formula | C16 H12 O5 |
| Molecular Weight | 284.26764000 |
| Nikkaji Number | J449.872K |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 541.10 °C. @ 760.00 mm Hg (est) |
| Flash Point | 406.00 °F. TCC ( 207.50 °C. ) (est) |
| logP (o/w) | 3.220 (est) |
| Soluble in | water, 30.94 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for negletein usage levels up to | not for fragrance use. |
| Recommendation for negletein flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
baicalein-7-methyl ether
baicalein-7-methylether
4H-1-
benzopyran-4-one, 5,6-dihydroxy-7-methoxy-2-phenyl-
5,6-
dihydroxy-7-methoxy-2-phenylchromen-4-one
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A new flavanone and other flavonoids from green perilla leaf extract inhibit nitric oxide production in interleukin 1β-treated hepatocytes.
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Multiple Mechanisms of Iron-Induced Amyloid Beta-Peptide Accumulation in SHSY5Y Cells: Protective Action of Negletein.
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Anti-inflammatory and immunomodulatory flavones from Actinocarya tibetica Benth.
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Protection of cells against oxidative stress by nanomolar levels of hydroxyflavones indicates a new type of intracellular antioxidant mechanism.
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Study of degradation behavior of baicalin during simulative blood sample processing with solid phase extraction technology and identification of the degradation product.
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[Study on the flavonoids from Mosla chinensis 'jiangxiangru'].
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Phenolic constituents with inhibitory activity against NFAT transcription from Desmos chinensis.