mansonone E
naphtho(1,8-bc)pyran-7,8-dione, 2,3-dihydro-3,6,9-trimethyl-
Identification
| Name | mansonone E |
| CAS Number | 5090-87-9 |
| FDA UNII | Search |
| Molecular Formula | C15 H14 O3 |
| Molecular Weight | 242.27418000 |
| Nikkaji Number | J13.434A |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 423.90 °C. @ 760.00 mm Hg (est) |
| Flash Point | 375.00 °F. TCC ( 190.70 °C. ) (est) |
| logP (o/w) | 3.090 (est) |
| Soluble in | water, 70.71 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for mansonone E usage levels up to | not for fragrance use. |
| Recommendation for mansonone E flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
naphtho(1,8-bc)pyran-7,8-dione, 2,3-dihydro-3,6,9-trimethyl-
3,6,9-
trimethyl-2,3-dihydrobenzo[de]chromene-7,8-dione
PubMed:
Design, synthesis and biological evaluation of novel mansonone E derivatives prepared via CuAAC click chemistry as topoisomerase II inhibitors.
PubMed:
Acetyl- and butyryl-cholinesterase inhibitory activities of mansorins and mansonones.
PubMed:
Cytotoxic and antibacterial sesquiterpenes from Thespesia populnea.
PubMed:
Thespesenone and dehydrooxoperezinone-6-methyl ether, new sesquiterpene quinones from Thespesia populnea.
PubMed:
Cytotoxic effects of mansonone E and F isolated from Ulmus pumila.
PubMed:
Antifungal, antioxidant and larvicidal activities of compounds isolated from the heartwood of Mansonia gagei.
PubMed:
Inhibition of the cytotoxicity of protein toxins by a novel plant metabolite, mansonone-D.
PubMed:
Effects of mansonones on lipid peroxidation, P450 monooxygenase activity, and superoxide anion generation by rat liver microsomes.