tolclofos-methyl
phosphorothioic acid, O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl ester
Identification
| Name | tolclofos-methyl |
| IUPAC | (2,6-dichloro-4-methylphenoxy)-dimethoxy-sulfanylidene-$l^{5}-phosphane |
| CAS Number | 57018-04-9 |
| EINECS | 260-515-3 |
| FDA UNII | G42OQL6F5B |
| Molecular Formula | C9 H11 Cl2 O3 P S |
| Molecular Weight | 301.12703200 |
| MDL Number | MFCD00078741 |
| Nikkaji Number | J1.904F |
| Beilstein | 2136521 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 79.00 °C. @ 760.00 mm Hg |
| Boiling Point | 338.50 °C. @ 760.00 mm Hg (est) |
| Flash Point | 317.00 °F. TCC ( 158.50 °C. ) (est) |
| logP (o/w) | 4.560 |
| Soluble in | water, 1.1 mg/L @ 25 °C (exp) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | oral-duck LD50 > 5000 mg/kg |
| Dermal Toxicity | skin-mouse LD50 > 5000 mg/kg |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | herbicides / pesticides |
| Recommendation for tolclofos-methyl usage levels up to | not for fragrance use. |
| Recommendation for tolclofos-methyl flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
(2,6-
dichloro-4-methylphenoxy)-dimethoxy-sulfanylidene-$l^{5}-phosphane
O-(2,6-
dichloro-4-methylphenyl) O,O-dimethyl phosphorothioate (9CI)
O-2,6-
dichloro-p-tolyl O,O-dimethyl phosphorothioate
O-(2,6-
dichloro-p-tolyl) O,O-dimethyl ester of phosphorothioic acid
O-(2,6-
dichloro-p-tolyl) O,O-dimethyl thiophosphate
O,O-
dimethyl O-(2,6-dichloro-4-methylphenyl)phosphorothioate
phosphorothioic acid, O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl ester
phosphorothioic acid, O-(2,6-dichloro-p-tolyl) O,O-dimethyl ester
risolex
rizolex
toclofos-methyl
PubMed:
Application of zirconium dioxide nanoparticle sorbent for the clean-up step in post-harvest pesticide residue analysis.
PubMed:
Spatio-temporal patterns of pesticide residues in the Turia and Júcar Rivers (Spain).
PubMed:
Molecularly imprinted nanomicrospheres as matrix solid-phase dispersant combined with gas chromatography for determination of four phosphorothioate pesticides in carrot and yacon.
PubMed:
Spatial distribution and partitioning of organophosphates pesticide in water and sediment from Sarno River and Estuary, Southern Italy.
PubMed:
TESTING SIDE-EFFECTS OF COMMON PESTICIDES ON A. SWIRSKII UNDER GREENHOUSE CIRCUMSTANCES.
PubMed:
Analytical approaches for the determination of pesticide residues in nutraceutical products and related matrices by chromatographic techniques coupled to mass spectrometry.
PubMed:
Effect of phenylpyrrole-resistance on fitness parameters and ochratoxin production in Aspergillus carbonarius.
PubMed:
Multiresidue pesticide analysis in Korean ginseng by gas chromatography-triple quadrupole tandem mass spectrometry.
PubMed:
Residues behavior of some fungicides applied on two greenhouse tomato varieties different in shape and weight.
PubMed:
Determination of organophosphorus pesticides in peanut oil by dispersive solid phase extraction gas chromatography-mass spectrometry.
PubMed:
Reduction of the movement and persistence of pesticides in soil through common agronomic practices.
PubMed:
Monitoring of pesticide residues in vegetables marketed in Al-Qassim region, Saudi Arabia.
PubMed:
Effects of chlorine on organophosphorus pesticides adsorbed on activated carbon: desorption and oxon formation.
PubMed:
Evaluation of the estrogenic activities of some pesticides and their combinations using MtT/Se cell proliferation assay.
PubMed:
Effect of pesticides on estrogen receptor transactivation in vitro: a comparison of stable transfected MVLN and transient transfected MCF-7 cells.
PubMed:
Evaluation of estrogenic activities of pesticides using an in vitro reporter gene assay.
PubMed:
Solid-phase microextraction liquid chromatography/tandem mass spectrometry to determine postharvest fungicides in fruits.
PubMed:
Interactions between nematophagous fungi and consequences for their potential as biological agents for the control of potato cyst nematodes.
PubMed:
Monitoring of five postharvest fungicides in fruit and vegetables by matrix solid-phase dispersion and liquid chromatography/mass spectrometry.
PubMed:
Effects of currently used pesticides in assays for estrogenicity, androgenicity, and aromatase activity in vitro.
PubMed:
Determination of fungicide residues in fruits and vegetables by liquid chromatography-atmospheric pressure chemical ionization mass spectrometry.
PubMed:
Evaluation of respiratory and cutaneous doses and urinary excretion of alkylphosphates by workers in greenhouses treated with omethoate, fenitrothion, and tolclofos-methyl.
PubMed:
Spontaneous reactivation of mouse plasma cholinesterase after inhibition by various organophosphorus compounds.