fluopyram
N-{2-(3-chloro-5-(trifluoromethyl)-2-pyridyl)ethyl}-alpha,alpha,alpha-trifluoro-o-toluamide
Identification
| Name | fluopyram |
| IUPAC | N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide |
| CAS Number | 658066-35-4 |
| FDA UNII | F0VT7K5302 |
| Molecular Formula | C16 H11 Cl F6 N2 O |
| Molecular Weight | 396.71928920 |
| MDL Number | MFCD17166960 |
| Nikkaji Number | J2.854.782J |
| Beilstein | 11323270 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 432.30 °C. @ 760.00 mm Hg (est) |
| Flash Point | 419.00 °F. TCC ( 215.20 °C. ) (est) |
| logP (o/w) | 4.360 (est) |
| Soluble in | water, 0.2631 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | herbicides / pesticides |
| Recommendation for fluopyram usage levels up to | not for fragrance use. |
| Recommendation for fluopyram flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
N-{2-(3-
chloro-5-(trifluoromethyl)-2-pyridyl)ethyl}-alpha,alpha,alpha-trifluoro-o-toluamide
N-[2-[3-
chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide
PubMed:
Thyroid tumor formation in the male mouse induced by fluopyram is mediated by activation of hepatic CAR/PXR nuclear receptors.
PubMed:
Liver tumor formation in female rat induced by fluopyram is mediated by CAR/PXR nuclear receptor activation.
PubMed:
Online solid phase extraction LC-MS/MS method for the analysis of succinate dehydrogenase inhibitor fungicides and its applicability to surface water samples.
PubMed:
Response of microbial community to a new fungicide fluopyram in the silty-loam agricultural soil.
PubMed:
Molecular characterisation and detection of resistance to succinate dehydrogenase inhibitor fungicides in Botryotinia fuckeliana (Botrytis cinerea).
PubMed:
Fitness and competitive ability of Botrytis cinerea field isolates with dual resistance to SDHI and QoI fungicides, associated with several sdhB and the cytb G143A mutations.
PubMed:
Site-directed mutagenesis of the P225, N230 and H272 residues of succinate dehydrogenase subunit B from Botrytis cinerea highlights different roles in enzyme activity and inhibitor binding.
PubMed:
Evaluation of dodine, fluopyram and penthiopyrad for the management of leaf spot and powdery mildew of tart cherry, and fungicide sensitivity screening of Michigan populations of Blumeriella jaapii.
PubMed:
Biological activity of the succinate dehydrogenase inhibitor fluopyram against Botrytis cinerea and fungal baseline sensitivity.
PubMed:
Molecular characterization of boscalid- and penthiopyrad-resistant isolates of Didymella bryoniae and assessment of their sensitivity to fluopyram.
PubMed:
Risk assessment studies on succinate dehydrogenase inhibitors, the new weapons in the battle to control Septoria leaf blotch in wheat.
PubMed:
Lack of cross-resistance to a novel succinate dehydrogenase inhibitor, fluopyram, in highly boscalid-resistant isolates of Corynespora cassiicola and Podosphaera xanthii.