methyl 3-methyl-2-oxovalerate

methyl 2-keto-3-methyl valerate methyl 2-keto-3-methylvalerate methyl 2-oxo-3-methyl pentanoate methyl 2-oxo-3-methylpentanoate methyl 2-oxo-3-methylvalerate methyl 3-methyl-2-oxopentanoate 3- methyl-2-oxopentanoic acid methyl ester 3- methyl-2-oxovaleric acid methyl ester pentanoic acid, 3-methyl-2-oxo-, methyl ester valeric acid, 3-methyl-2-oxo-, methyl ester PubMed: Nuclear magnetic resonance metabolomics of iron deficiency in soybean leaves. PubMed: Biomarkers for type 2 diabetes and impaired fasting glucose using a nontargeted metabolomics approach. PubMed: Early metabolic adaptation in C57BL/6 mice resistant to high fat diet induced weight gain involves an activation of mitochondrial oxidative pathways. PubMed: Quantitative metabolomic profiling of serum, plasma, and urine by (1)H NMR spectroscopy discriminates between patients with inflammatory bowel disease and healthy individuals. PubMed: Streptococcus pneumoniae and Staphylococcus aureus pneumonia induce distinct metabolic responses. PubMed: Metabolite profiling of human amniotic fluid by hyphenated nuclear magnetic resonance spectroscopy. PubMed: Effect of the branched-chain alpha-keto acids accumulating in maple syrup urine disease on S100B release from glial cells. PubMed: Creatine and antioxidant treatment prevent the inhibition of creatine kinase activity and the morphological alterations of C6 glioma cells induced by the branched-chain alpha-keto acids accumulating in maple syrup urine disease. PubMed: Protective effect of alpha-keto-beta-methyl-n-valeric acid on BV-2 microglia under hypoxia or oxidative stress. PubMed: alpha-keto-beta-methyl-n-valeric acid diminishes reactive oxygen species and alters endoplasmic reticulum Ca(2+) stores. PubMed: A conditional marker gene allowing both positive and negative selection in plants. PubMed: Inhibition of alpha-ketoglutarate dehydrogenase complex promotes cytochrome c release from mitochondria, caspase-3 activation, and necrotic cell death. PubMed: Lacticin 3147 favours isoleucine transamination by Lactococcus lactis IFPL359 in a cheese-model system. PubMed: Inhibition of the alpha-ketoglutarate dehydrogenase complex alters mitochondrial function and cellular calcium regulation. PubMed: Mycobacterium tuberculosis ketopantoate hydroxymethyltransferase: tetrahydrofolate-independent hydroxymethyltransferase and enolization reactions with alpha-keto acids. PubMed: Pharmacological evidence that alpha-ketoisovaleric acid induces convulsions through GABAergic and glutamatergic mechanisms in rats. PubMed: Analysis of (S)- and (R)-3-methyl-2-oxopentanoate enantiomorphs in body fluids. PubMed: Chloride-dependent inhibition of vesicular glutamate uptake by alpha-keto acids accumulated in maple syrup urine disease. PubMed: Branched-chain alpha-keto acid catabolism via the gene products of the bkd operon in Enterococcus faecalis: a new, secreted metabolite serving as a temporary redox sink. PubMed: Formation of L-alloisoleucine in vivo: an L-[13C]isoleucine study in man. PubMed: Renal clearance of branched-chain L-amino and 2-oxo acids in maple syrup urine disease. PubMed: Determination of R- and S-3-methyl-2-oxopentanoate enantiomers in human plasma: suitable method for label enrichment analysis. PubMed: Production of acyl-carnitines from the metabolism of [U-14C]3-methyl-2-oxopentanoate by rat liver and skeletal muscle mitochondria. PubMed: Alpha-keto acid metabolism by hepatocytes cultured in a hybrid liver support bioreactor. PubMed: Purification and characterization of the branched chain alpha-ketoacid dehydrogenase complex from Saccharomyces cerevisiae. PubMed: Comparative metabolism and structure of BCKD-E2 in primary biliary cirrhosis. PubMed: Oral L-alloisoleucine loading studies in healthy subjects and in patients with maple syrup urine disease. PubMed: An improved assay for pyruvate dehydrogenase in liver and heart. PubMed: On the mechanism of L-alloisoleucine formation: studies on a healthy subject and in fibroblasts from normals and patients with maple syrup urine disease. PubMed: Analysis of maple syrup urine disease in cell culture: use of substrates. PubMed: Transamination and oxidative decarboxylation of L-isoleucine, L-alloisoleucine and related 2-oxo acids in perfused rat hind limb muscle. PubMed: Regulation of branched-chain 2-oxo acid dehydrogenase activity during exercise. PubMed: Transamination and oxidative decarboxylation rates of branched-chain 2-oxo acids in cultured human skin fibroblasts. PubMed: Activation of branched-chain alpha-ketoacid dehydrogenase in isolated hepatocytes by branched-chain alpha-ketoacids. PubMed: Phosphorylation of branched-chain 2-oxo acid dehydrogenase complex in isolated hepatocytes. PubMed: A study of the metabolism of [U-14C]3-methyl-2-oxopentanoate by rat liver mitochondria using h.p.l.c. with continuous on-line monitoring of radioactive intact acyl-coenzyme A intermediates. PubMed: Pharmacokinetic and metabolic interrelationships among branched-chain keto and amino acids in humans. PubMed: Metabolism of valine and 3-methyl-2-oxobutanoate by the isolated perfused rat kidney. PubMed: Branched-chain amino acid metabolism. PubMed: The relationship between branched-chain amino acids and alpha-keto acids in blood in uremia. PubMed: Binding of branched-chain 2-oxo acids to bovine serum albumin. PubMed: Blood levels of branched-chain alpha-keto acids in uremia: effect of an oral glucose tolerance test. PubMed: Dynamics of O2 consumption in rat pancreatic islets. PubMed: 2-oxocarboxylic acids and function of pancreatic islets in obese-hyperglycaemic mice. Insulin secretion in relation to 45Ca uptake and metabolism. PubMed: Partial purification and properties of branched-chain 2-oxo acid dehydrogenase of ox liver. PubMed: [Vitamin B 6 biosynthesis in Bacillus subtilis].