Identification

Namemint lactone
IUPAC3,6-dimethyl-5,6,7,7a-tetrahydro-4H-1-benzofuran-2-one
CAS Number13341-72-5
EINECS236-390-6
FDA UNIIEWW1JFM977
Molecular FormulaC10 H14 O2
Molecular Weight166.21998000
MDL NumberMFCD00209516
Nikkaji NumberJ40.149H
CoE Number10036

Regulatory

JECFA Food Flavoring1162 mintlactone
DG SANTE Food Flavourings10.036 5,6,7,7a-tetrahydro-3,6-dimethylbenzofuran-2(4H)-one
FEMA Number3764
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)13341-72-5 ; MINTLACTONE

Physical Properties

Appearance colorless clear liquid (est)
Assay 98.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 1.05800 to 1.06300 @ 25.00 °C.
Pounds per Gallon - (est). 8.804 to 8.845
Refractive Index 1.49700 to 1.50300 @ 20.00 °C.
Boiling Point 87.00 to 89.00 °C. @ 25.00 mm Hg, 302.00 to 303.00 °C. @ 760.00 mm Hg
Vapor Pressure 0.001000 mmHg @ 25.00 °C. (est)
Flash Point 176.00 °F. TCC ( 80.00 °C. )
logP (o/w) 1.811 (est)
Soluble in alcohol

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesperfuming agents

Organoleptic Properties

Odor Description
at 100.00 %.
sweet, creamy, coumarinic and coconut with a powdery tobacco nuance
Taste Description at 10.00 ppm.

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavor and fragrance agents
RIFM Fragrance Material Safety AssessmentSearch
Recommendation for mint lactone usage levels up to1.0000 % in the fragrance concentrate.
Maximised Survey-derived Daily Intakes (MSDI-EU)8.00 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA)1.00 (μg/capita/day)
Structure ClassIII
baked goods-
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum-
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

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Potential Uses

FR cherry FR coconut FR spearmint FR vanilla

Natural Occurrence

cornmint pennyroyal oil peppermint

Synonyms

2(4H)- benzofuranone, 5,6,7,7a-tetrahydro-3,6-dimethyl- 3,6- dimethyl-5,6,7,7a-tetrahydro-1-benzofuran-2(4H)-one 3,6- dimethyl-5,6,7,7a-tetrahydro-4H-1-benzofuran-2-one 3,6- dimethyl-5,6,7,7a-tetrahydro-4H-benzofuran-2-one menthalactone mint furanone mint lactone mintlactone 5,6,7,7a- tetrahydro-3,6-dimethyl-(4H)-benzofuran-2-one 5,6,7,7a- tetrahydro-3,6-dimethyl-2(4H)-benzofuranone 5,6,7,7a- tetrahydro-3,6-dimethylbenzofuran-2(4H)-one 5,6,7,7a- tetrahydro-3,6-trimethyl-2(4H)-benzofuranone tetrahydrodimethyl benzofuran-2-one PubMed: Protein kinase and HDAC inhibitors from the endophytic fungus Epicoccum nigrum. PubMed: Bioactivities of some essential oils against the camel nasal botfly, Cephalopina titillator. PubMed: Two new monoterpenes from the fruits of Illicium lanceolatum. PubMed: Chemical composition of the essential oil from Corsican Mentha aquatica--combined analysis by GC(RI), GC-MS and 13C NMR spectroscopy. PubMed: Anti-Candida activity of Mentha arvensis and Turnera ulmifolia. PubMed: Tolerability of everolimus-based immunosuppression in maintenance liver transplant recipients. PubMed: Differential proteome and phosphoproteome signatures in human T-lymphoblast cells induced by sirolimus. PubMed: Menthalactone, a new analgesic from Mentha cordifolia Opiz. Leaves. PubMed: Synthetic studies on neoclerodane diterpenes from Salvia splendens: oxidative modifications of ring A. PubMed: The antimicrobial activity of four commercial essential oils in combination with conventional antimicrobials. PubMed: Pharmacokinetics, efficacy, and safety of mycophenolate mofetil in combination with standard-dose or reduced-dose tacrolimus in liver transplant recipients. PubMed: Nitration versus nitrosation chemistry of menthofuran: remarkable fragmentation and dimerization pathways and expeditious entry into dehydromenthofurolactone. PubMed: Conversion to sirolimus-based immunosuppression in maintenance liver transplantation patients. PubMed: Use of a superabsorbent polymer for the preconcentration of volatile components from complex matrices. PubMed: Long-term renal function after liver transplantation is related to calcineurin inhibitors blood levels. PubMed: Antidiarrhoeal activity of some Egyptian medicinal plant extracts. PubMed: Immunosuppression for pancreatic islet transplantation. PubMed: Lactones. 21. Synthesis and odoriferous properties of lactones with the p-menthane system. PubMed: Munc18 interacting proteins: ADP-ribosylation factor-dependent coat proteins that regulate the traffic of beta-Alzheimer's precursor protein. PubMed: Hepatitis associated with Kava, a herbal remedy for anxiety. PubMed: A generalist herbivore in a specialist mode Metabolic, sequestrative, and defensive consequences. PubMed: Metabolism of Monoterpenes : Evidence for the Function of Monoterpene Catabolism in Peppermint (Mentha piperita) Rhizomes. PubMed: Metabolism of Monoterpenes : Early Steps in the Metabolism of d-Neomenthyl-beta-d-Glucoside in Peppermint (Mentha piperita) Rhizomes.