Identification

Namecinnamomum cassia bark oil
IUPACcinnamomum cassia blume bark oil
CAS Number8007-80-5
FDA UNIIA4WO0626T5
MDL NumberMFCD00130805
CoE Number131

Regulatory

FEMA Number2258
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)8007-80-5 ; CINNAMON BARK, OIL (CINNAMOMUM SPP.)
FDA RegulationFDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE

Physical Properties

Appearance colorless to pale yellow clear liquid (est)
Food Chemicals Codex Listed No
Soluble in alcohol

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesantimicrobial agents

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavor and fragrance agents
RIFM Fragrance Material Safety AssessmentSearch
fragrance material specificationThe prime allergen is Cinnamic aldehyde. The concentration of Cinnamic aldehyde in the finished cosmetic product should not exceed 0.1%.

No supplier data available

Potential Uses

FR agate FR allspice FR almond FR amber FR balsam FR bayberry FL/FR benzoin absolute replacer FR bouquet FR carnation FR cassia FR cherry blossom FR chypre FR cinnamon FR gingerbread FR herbal FR lychee FR mimosa FR musk FR patchouli FR pina colada FR pine FR pine forest FR powder FR pumpkin pie FR rose FR rose dog rose FR sandalwood FR spice FR sweet grass FR vanilla FR verbena FR wallflower FR windsor soap FR woody

Natural Occurrence

cassia bark

Synonyms

camphorina cassia bark oil cassia bark oil cinnamomum aromaticum bark oil cinnamomum longifolium bark oil cinnamomum medium bark oil cinnamomum nitidum bark oil cinnamon bark oil (cinnamomum cassia) china laurus cassia bark oil persea cassia bark oil volatile oil obtained from the bark of cinnamomum cassia, lauraceae PubMed: Differentiating Parts of Cinnamomum Cassia using LC-qTOF-MS in Conjunction with Principal Component Analysis. PubMed: Agrimonia pilosa Ledeb., Cinnamomum cassia Blume, and Lonicera japonica Thunb. protect against cognitive dysfunction and energy and glucose dysregulation by reducing neuroinflammation and hippocampal insulin resistance in β-amyloid-infused rats. PubMed: Ba-Wei-Die-Huang-Wan (Hachimi-jio-gan) can ameliorate cyclophosphamide-induced ongoing bladder overactivity and acidic adenosine triphosphate solution-induced hyperactivity on rats prestimulated bladder. PubMed: Cinnamomum cassia Suppresses Caspase-9 through Stimulation of AKT1 in MCF-7 Cells but Not in MDA-MB-231 Cells. PubMed: Cinnamaldehyde affects the biological behavior of human colorectal cancer cells and induces apoptosis via inhibition of the PI3K/Akt signaling pathway. PubMed: In Vitro Antiviral Activity of Cinnamomum cassia and Its Nanoparticles Against H7N3 Influenza A Virus. PubMed: Cinnamomum cassia: an implication of serotonin reuptake inhibition in animal models of depression. PubMed: Cinnamon and its Components Suppress Vascular Smooth Muscle Cell Proliferation by Up-Regulating Cyclin-Dependent Kinase Inhibitors. PubMed: Essential Oils, Silver Nanoparticles and Propolis as Alternative Agents Against Fluconazole Resistant Candida albicans, Candida glabrata and Candida krusei Clinical Isolates. PubMed: Anti-diabetic nephropathy compounds from Cinnamomum cassia. PubMed: Immunosuppressive Effects of A-Type Procyanidin Oligomers from Cinnamomum tamala. PubMed: Cinnamomum cassia bark produced by solid-state fermentation with Phellinus baumii has the potential to alleviate atopic dermatitis-related symptoms. PubMed: A new phenolic glycoside from the barks of Cinnamomum cassia. PubMed: Diterpenoids with Immunosuppressive Activities from Cinnamomum cassia. PubMed: Traditional formula, modern application: chinese medicine formula sini tang improves early ventricular remodeling and cardiac function after myocardial infarction in rats. PubMed: Effect of Cinnamomum cassia methanol extract and sildenafil on arginase and sexual function of young male Wistar rats. PubMed: Evaluation of the in vitro anti-hyperglycemic effect of Cinnamomum cassia derived phenolic phytochemicals, via carbohydrate hydrolyzing enzyme inhibition. PubMed: Interaction of gypsum and the rhizome of Anemarrhena asphodeloides plays an important role in anti-allergic effects of byakkokakeishito in mice. PubMed: Cinnamaldehyde/chemotherapeutic agents interaction and drug-metabolizing genes in colorectal cancer. PubMed: Identification of compounds from the water soluble extract of Cinnamomum cassia barks and their inhibitory effects against high-glucose-induced mesangial cells. PubMed: A novel concept for detoxification: complexation between aconitine and liquiritin in a Chinese herbal formula ('Sini Tang'). PubMed: Antitumor activity of 2-hydroxycinnamaldehyde for human colon cancer cells through suppression of β-catenin signaling. PubMed: Fumigant toxicity of plant essential oils against Camptomyia corticalis (Diptera: Cecidomyiidae). PubMed: Antioxidant activity of various parts of Cinnamomum cassia extracted with different extraction methods. PubMed: Bioactive A-type proanthocyanidins from Cinnamomum cassia. PubMed: Differential antiproliferation effect of 2'-benzoyloxycinnamaldehyde in K-ras-transformed cells via downregulation of thiol antioxidants. PubMed: 2'-Hydroxycinnamaldehyde targets low-density lipoprotein receptor-related protein-1 to inhibit lipopolysaccharide-induced microglial activation. PubMed: Hypoglycemic activities of A- and B-type procyanidin oligomer-rich extracts from different Cinnamon barks. PubMed: Platelet anti-aggregation activities of compounds from Cinnamomum cassia. PubMed: Anti-inflammatory activities of essential oils and their constituents from different provenances of indigenous cinnamon (Cinnamomum osmophloeum) leaves. PubMed: The cinnamon-derived dietary factor cinnamic aldehyde activates the Nrf2-dependent antioxidant response in human epithelial colon cells. PubMed: Cinnamon extract induces tumor cell death through inhibition of NFkappaB and AP1. PubMed: Aqueous cinnamon extract (ACE-c) from the bark of Cinnamomum cassia causes apoptosis in human cervical cancer cell line (SiHa) through loss of mitochondrial membrane potential. PubMed: Selective stimulation by cinnamaldehyde of progesterone secretion in human adrenal cells. PubMed: Cinnamomum cassia bark in two herbal formulas increases life span in Caenorhabditis elegans via insulin signaling and stress response pathways. PubMed: Cinnamic acid, from the bark of Cinnamomum cassia, regulates glucose transport via activation of GLUT4 on L6 myotubes in a phosphatidylinositol 3-kinase-independent manner. PubMed: [Analysis on the chemical compositions of the volatile oil from ultramicro-powder and common grinding powder of Cinnamomum cassia]. PubMed: Quality assessment of cortex cinnamomi by HPLC chemical fingerprint, principle component analysis and cluster analysis. PubMed: Apoptosis induction of 2'-hydroxycinnamaldehyde as a proteasome inhibitor is associated with ER stress and mitochondrial perturbation in cancer cells. PubMed: Nematicidal Activity of Cassia and Cinnamon Oil Compounds and Related Compounds toward Bursaphelenchus xylophilus (Nematoda: Parasitaphelenchidae). PubMed: Stimulatory effects of extract prepared from the bark of Cinnamomum cassia blume on the function of osteoblastic MC3T3-E1 cells. PubMed: Repellency of Cinnamomum cassia bark compounds and cream containing cassia oil to Aedes aegypti (Diptera: Culicidae) under laboratory and indoor conditions. PubMed: In vitro efficacy of 75 essential oils against Aspergillus niger. PubMed: Antimicrobial effects of selected plant essential oils on the growth of a Pseudomonas putida strain isolated from meat. PubMed: Antimicrobial activities of cinnamon oil and cinnamaldehyde from the Chinese medicinal herb Cinnamomum cassia Blume. PubMed: Delayed occurrence of H-ras12V-induced hepatocellular carcinoma with long-term treatment with cinnamaldehydes. PubMed: Effects of cassia oil on serum and hepatic uric acid levels in oxonate-induced mice and xanthine dehydrogenase and xanthine oxidase activities in mouse liver. PubMed: Antidiabetic effect of Cinnamomum cassia and Cinnamomum zeylanicum in vivo and in vitro. PubMed: Authentication and quantitative analysis on the chemical profile of cassia bark (cortex cinnamomi) by high-pressure liquid chromatography. PubMed: Inhibitory effect of 2'-hydroxycinnamaldehyde on nitric oxide production through inhibition of NF-kappa B activation in RAW 264.7 cells. PubMed: Inhibition of Trypanosoma cruzi by plant extracts used in Chinese medicine. PubMed: Cinnamaldehyde and 2-methoxycinnamaldehyde as NF-kappaB inhibitors from Cinnamomum cassia. PubMed: [Isolation of genomic DNA from Cinnamomum cassia Presl]. PubMed: Repellency of aromatic medicinal plant extracts and a steam distillate to Aedes aegypti. PubMed: Inhibitory effect of Sihoga-Yonggol-Moryo-Tang on matrix metalloproteinase-2 and -9 activities and invasiveness potential of hepatocellular carcinoma. PubMed: Antioxidant activity of Cinnamomum cassia. PubMed: Cinnamaldehyde induces apoptosis by ROS-mediated mitochondrial permeability transition in human promyelocytic leukemia HL-60 cells. PubMed: Measurement of plasma procyanidin B-2 and procyanidin B-3 levels after oral administration in rat. PubMed: [Comparison studies on chemical constituents of essential oil from Ramulus Cinnamomi and Cortex Cinnamomi by GC-MS]. PubMed: Inhibitory activity of Cinnamomum cassia bark-derived component against rat lens aldose reductase. PubMed: Suppression effect of Cinnamomum cassia bark-derived component on nitric oxide synthase. PubMed: Constituents of the essential oil of the Cinnamomum cassia stem bark and the biological properties. PubMed: Growth-Inhibiting Effects of Cinnamomum cassia Bark-Derived Materials on Human Intestinal Bacteria. PubMed: A survey of some Indian medicinal plants for anti-human immunodeficiency virus (HIV) activity. PubMed: Extract prepared from the bark of Cinnamomum cassia Blume prevents glutamate-induced neuronal death in cultured cerebellar granule cells. PubMed: Insecticidal and fumigant activities of Cinnamomum cassia bark-derived materials against Mechoris ursulus (Coleoptera: attelabidae). PubMed: Synthesis and in vitro cytotoxicity of cinnamaldehydes to human solid tumor cells. PubMed: Cinnamaldehyde inhibits lymphocyte proliferation and modulates T-cell differentiation. PubMed: 2'-Hydroxycinnamaldehyde from stem bark of Cinnamomum cassia. PubMed: Pharmacotherapeutic effects of kuei-chih-fu-ling-wan (keishi-bukuryo-gan) on human uterine myomas. PubMed: A reticuloendothelial system-activating arabinoxylan from the bark of Cinnamomum cassia. PubMed: Antiulcerogenic compounds isolated from Chinese cinnamon. PubMed: Effects of a Chinese herbal medicine, keishi-bukuryo-gan, on the gonadal system of rats. PubMed: [Pharmacological studies of Cinnamomum cassia bark. Part I. Effects on the blood and cardiovascular system (author's transl)].