artichoke leaf
cynara scolymus leaf
Identification
| Name | artichoke leaf |
| IUPAC | cynara scolymus l. leaf |
| CAS Number | 977038-45-1 |
| FDA UNII | Search |
| CoE Number | 168 |
Regulatory
| FDA Mainterm (SATF) | 977038-45-1 ; ARTICHOKE LEAVES (CYNARA SCOLYMUS L.) |
| FDA Regulation | FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION |
Physical Properties
| Food Chemicals Codex Listed | No |
Organoleptic Properties
| Odor Strength | low |
| Odor Description | at 100.00 %. |
| Taste Description | artichoke green leafy |
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for artichoke leaf usage levels up to | not for fragrance use. |
| Recommendation for artichoke leaf flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
cynara scolymus leaf
PubMed:
An integrated approach to the evaluation of a metabolomic fingerprint for a phytocomplex. Focus on artichoke [Cynara cardunculus subsp. scolymus] leaf.
PubMed:
Effects of artichoke (Cynara scolymus) leaf and bloom head extracts on chemically induced DNA lesions in Drosophila melanogaster.
PubMed:
Establishment of fungal entomopathogens Beauveria bassiana and Bionectria ochroleuca (Ascomycota: Hypocreales) as endophytes on artichoke Cynara scolymus.
PubMed:
Artichoke, cynarin and cyanidin downregulate the expression of inducible nitric oxide synthase in human coronary smooth muscle cells.
PubMed:
Investigation of the in vivo antioxidative activity of Cynara scolymus (artichoke) leaf extract in the streptozotocin-induced diabetic rat.
PubMed:
Cynara Scolymus Leaf Extract Stimulates Adipogenesis in 3T3-L1 Preadipocytes and Suppresses Hepatic Glucose Output in H4IIE Hepatocytes.
PubMed:
Metabolomics driven analysis of artichoke leaf and its commercial products via UHPLC-q-TOF-MS and chemometrics.
PubMed:
Protective activity of Cynara scolymus L. leaf extract against chemically induced complex genomic alterations in CHO cells.
PubMed:
A combined natural supplement lowers LDL cholesterol in subjects with moderate untreated hypercholesterolemia: a randomized placebo-controlled trial.
PubMed:
Protective effect of artichoke (Cynara scolymus) leaf extract against lead toxicity in rat.
PubMed:
Effective protein extraction protocol for proteomics studies of Jerusalem artichoke leaves.
PubMed:
Artichoke leaf extract for treating hypercholesterolaemia.
PubMed:
[Development and validation of method for the determination of cynarin, luteolin in plasma].
PubMed:
In vivo genotoxicity evaluation of an artichoke (Cynara scolymus L.) aqueous extract.
PubMed:
Effect on LDL-cholesterol of a large dose of a dietary supplement with plant extracts in subjects with untreated moderate hypercholesterolaemia: a randomised, double-blind, placebo-controlled study.
PubMed:
Effect of zeolite nano-materials and artichoke (Cynara scolymus L.) leaf extract on increase in urinary clearance of systematically absorbed nicotine.
PubMed:
Artichoke induces genetic toxicity and decreases ethyl methanesulfonate-related DNA damage in Chinese hamster ovary cells.
PubMed:
Beneficial effects of artichoke leaf extract supplementation on increasing HDL-cholesterol in subjects with primary mild hypercholesterolaemia: a double-blind, randomized, placebo-controlled trial.
PubMed:
LDL-cholesterol-lowering effect of a dietary supplement with plant extracts in subjects with moderate hypercholesterolemia.
PubMed:
Artichoke extract lowered plasma cholesterol and increased fecal bile acids in Golden Syrian hamsters.
PubMed:
Laboratory and field experimental evaluation of host plant specificity of Aceria solstitialis, a prospective biological control agent of yellow starthistle.
PubMed:
Quantification of cynaropicrin in artichoke leaf extracts by ¹H NMR spectroscopy.
PubMed:
Rapid determination of caffeoylquinic acid derivatives in Cynara scolymus L. by ultra-fast liquid chromatography/tandem mass spectrometry based on a fused core C18 column.
PubMed:
[Phytotherapy with a mixture of dry extracts with hepato-protective effects containing artichoke leaves in the management of functional dyspepsia symptoms].
PubMed:
Effects of artichoke leaf extract on acute gastric mucosal injury in rats.
PubMed:
Artichoke leaf extract for treating hypercholesterolaemia.
PubMed:
Artichoke leaf extract reduces oxidative stress and lipoprotein dyshomeostasis in rats fed on high cholesterol diet.
PubMed:
Effect of artichoke leaf extract on hepatic and cardiac oxidative stress in rats fed on high cholesterol diet.
PubMed:
Chronic copper toxicosis in sheep following the use of copper sulfate as a fungicide on fruit trees.
PubMed:
Proteomics in globe artichoke: protein extraction and sample complexity reduction by PEG fractionation.
PubMed:
Artichoke leaf juice contains antihypertensive effect in patients with mild hypertension.
PubMed:
Molecular Identification, Reverse Transcription-Polymerase Chain Reaction Detection, Host Reactions, and Specific Cytopathology of Artichoke yellow ringspot virus Infecting Onion Crops.
PubMed:
Stress-induced biosynthesis of dicaffeoylquinic acids in globe artichoke.
PubMed:
Effect of pretreatment with artichoke extract on carbon tetrachloride-induced liver injury and oxidative stress.
PubMed:
The influence of supplementation with artichoke (Cynara scolymus L.) extract on selected redox parameters in rowers.
PubMed:
Artichoke leaf extract (Cynara scolymus) reduces plasma cholesterol in otherwise healthy hypercholesterolemic adults: a randomized, double blind placebo controlled trial.
PubMed:
Flavonoids of Cynara scolymus possess potent xanthinoxidase inhibitory activity in vitro but are devoid of hypouricemic effects in rats after oral application.
PubMed:
Characterization and differential expression analysis of artichoke phenylalanine ammonia-lyase-coding sequences.
PubMed:
Clinical uses of artichoke leaf extract.
PubMed:
Heavy metal contents in horticultural crops of a representative area of the European Mediterranean region.
PubMed:
Time-resolved spectral studies of blue-green fluorescence of artichoke (Cynara cardunculus L. Var. Scolymus) leaves: identification of chlorogenic acid as one of the major fluorophores and age-mediated changes.
PubMed:
Bioavailability and pharmacokinetics of caffeoylquinic acids and flavonoids after oral administration of Artichoke leaf extracts in humans.
PubMed:
Phenolic compounds from the leaf extract of artichoke (Cynara scolymus L.) and their antimicrobial activities.
PubMed:
Artichoke leaf extract reduces symptoms of irritable bowel syndrome and improves quality of life in otherwise healthy volunteers suffering from concomitant dyspepsia: a subset analysis.
PubMed:
Flavonoids from artichoke (Cynara scolymus L.) up-regulate endothelial-type nitric-oxide synthase gene expression in human endothelial cells.
PubMed:
Commercial and laboratory extracts from artichoke leaves: estimation of caffeoyl esters and flavonoidic compounds content.
PubMed:
Efficacy of artichoke leaf extract in the treatment of patients with functional dyspepsia: a six-week placebo-controlled, double-blind, multicentre trial.
PubMed:
Validated method for the determination of six metabolites derived from artichoke leaf extract in human plasma by high-performance liquid chromatography-coulometric-array detection.
PubMed:
Screening pharmaceutical preparations containing extracts of turmeric rhizome, artichoke leaf, devil's claw root and garlic or salmon oil for antioxidant capacity.
PubMed:
Artichoke leaf extract reduces mild dyspepsia in an open study.
PubMed:
Choleretic activity and biliary elimination of lipids and bile acids induced by an artichoke leaf extract in rats.
PubMed:
Analysis of antioxidative phenolic compounds in artichoke (Cynara scolymus L.).
PubMed:
Fructan biosynthesis in transgenic plants.
PubMed:
Prevention of taurolithocholate-induced hepatic bile canalicular distortions by HPLC-characterized extracts of artichoke (Cynara scolymus) leaves.
PubMed:
Anticholestatic activity of flavonoids from artichoke (Cynara scolymus L.) and of their metabolites.
PubMed:
Artichoke leaf extract for treating hypercholesterolaemia.
PubMed:
Activity of artichoke leaf extract on reactive oxygen species in human leukocytes.
PubMed:
Artichoke leaf extract reduces symptoms of irritable bowel syndrome in a post-marketing surveillance study.
PubMed:
Artichoke leaf extract - Recent findings reflecting effects on lipid metabolism, liver and gastrointestinal tracts.
PubMed:
[On the distribution of o-dihydroxyphenols of the caffeic acid type in the artichoke leaf and on their variation as a function of temperature].