daphne genkwa bud extract
extract of the buds of daphne genkwa, thymelaeaceae
Identification
| Name | daphne genkwa bud extract |
Regulatory
Physical Properties
| Food Chemicals Codex Listed | No |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | skin conditioning |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | cosmetic ingredient for skin conditioning |
| Recommendation for daphne genkwa bud extract usage levels up to | not for fragrance use. |
| Recommendation for daphne genkwa bud extract flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
daphne fortunei bud extract
daphne genkwa fo. taitoensis bud extract
daphne genkwa var. fortunei bud extract
extract of the buds of daphne genkwa, thymelaeaceae
wikstroemia genkwa bud extract
yuan hua bud extract
PubMed:
Daphnane Diterpenes from Daphne genkwa Activate Nurr1 and Have a Neuroprotective Effect in an Animal Model of Parkinson's Disease.
PubMed:
Genkwadaphnin promotes leukocyte migration by increasing CD44 expression via PKD1/NF-κB signaling pathway.
PubMed:
Anti-Tumor Activity of Yuanhuacine by Regulating AMPK/mTOR Signaling Pathway and Actin Cytoskeleton Organization in Non-Small Cell Lung Cancer Cells.
PubMed:
Antitumor Activity of Total Flavonoids from Daphne genkwa in Colorectal Cancer.
PubMed:
Sibjotang Increases Atrial Natriuretic Peptide Secretion in Beating Rabbit Atria.
PubMed:
PRDM1, a Tumor-Suppressor Gene, is Induced by Genkwadaphnin in Human Colon Cancer SW620 Cells.
PubMed:
Pharmacokinetic profile and metabolite identification of yuanhuapine, a bioactive component in Daphne genkwa by ultra-high performance liquid chromatography coupled with tandem mass spectrometry.
PubMed:
Anti-herpes Activity of Vinegar-processed Daphne genkwa Flos Via Enhancement of Natural Killer Cell Activity.
PubMed:
Functional restoration of exhausted CD4(+) and CD8(+) T cells in chronic viral infection by vinegar-processed flos of Daphne genkwa.
PubMed:
A new highly oxygenated daphnane diterpene esters from the flower buds of Daphne genkwa.
PubMed:
Genkwadaphnin induces IFN-γ via PKD1/NF-κB/STAT1 dependent pathway in NK-92 cells.
PubMed:
Genkwadaphnin induces reactive oxygen species (ROS)-mediated apoptosis of squamous cell carcinoma (SCC) cells.
PubMed:
Anti-inflammatory effects of 81 chinese herb extracts and their correlation with the characteristics of traditional chinese medicine.
PubMed:
Antioxidant effects of Genkwa flos flavonoids on Freund׳s adjuvant-induced rheumatoid arthritis in rats.
PubMed:
Full toxicity assessment of Genkwa Flos and the underlying mechanism in nematode Caenorhabditis elegans.
PubMed:
Apigenin isolated from Daphne genkwa Siebold et Zucc. inhibits 3T3-L1 preadipocyte differentiation through a modulation of mitotic clonal expansion.
PubMed:
Anti-rheumatoid arthritic activity of flavonoids from Daphne genkwa.
PubMed:
STUDIES ON A SIMPLE AND EFFICIENT METHOD FOR LARGE-SCALE PREPARATION OF GENKWANIN FROM DAPHNE GENKWA SIEB. ET ZUCC. USING NORMAL-PHASE FLASH CHROMATOGRAPHY.
PubMed:
The Chinese herb isolate yuanhuacine (YHL-14) induces G2/M arrest in human cancer cells by up-regulating p21 protein expression through an p53 protein-independent cascade.
PubMed:
Isolation of anticancer constituents from flos genkwa (Daphne genkwa Sieb.et Zucc.) through bioassay-guided procedures.
PubMed:
Anticancer Activity of Novel Daphnane Diterpenoids from Daphne genkwa through Cell-Cycle Arrest and Suppression of Akt/STAT/Src Signalings in Human Lung Cancer Cells.
PubMed:
Melanogenesis inhibitory daphnane diterpenoids from the flower buds of Daphne genkwa.
PubMed:
Two new tigliane diterpene esters from the flower buds of Daphne genkwa.
PubMed:
Daphnane-type diterpenes with inhibitory activities against human cancer cell lines from Daphne genkwa.
PubMed:
Daphne Genkwa sieb. Et zucc. Water-soluble extracts act on enterovirus 71 by inhibiting viral entry.
PubMed:
Zuonin B Inhibits Lipopolysaccharide-Induced Inflammation via Downregulation of the ERK1/2 and JNK Pathways in RAW264.7 Macrophages.
PubMed:
Anticancer drugs from traditional toxic Chinese medicines.
PubMed:
Growth inhibition of human lung cancer cells via down-regulation of epidermal growth factor receptor signaling by yuanhuadine, a daphnane diterpene from Daphne genkwa.
PubMed:
PREPARATIVE ISOLATION AND PURIFICATION OF FOUR FLAVONOIDS FROM DAPHNE GENKWA SIEB. ET ZUCC. BY HIGH-SPEED COUNTERCURRENT CHROMATOGRAPHY.
PubMed:
A simple and efficient protocol for large-scale preparation of three flavonoids from the flower of Daphne genkwa by combination of macroporous resin and counter-current chromatography.
PubMed:
Daphnane diterpene esters with anti-proliferative activities against human lung cancer cells from Daphne genkwa.
PubMed:
[Studies on chemical constituents of Daphne genkwa].
PubMed:
[RP-HPLC determination of tiliroside in Daphne genkwa].
PubMed:
Anti-inflammatory activity of (-)-aptosimon isolated from Daphne genkwa in RAW264.7 cells.
PubMed:
[Effect of Glycyrrhiza inflata and Daphne genkwa on permeabilities of rhodamine 123, a P-glycoprotein substrate across rat jejunum membranes in vitro].
PubMed:
Screening of Korean medicinal plants for possible osteoclastogenesis effects in vitro.
PubMed:
(-)-Syringaresinol inhibits proliferation of human promyelocytic HL-60 leukemia cells via G1 arrest and apoptosis.
PubMed:
A new flavanol from Daphne genkwa.
PubMed:
Evaluation of Daphne genkwa diterpenes: fingerprint and quantitative analysis by high performance liquid chromatography.
PubMed:
Daphnane diterpene esters isolated from flower buds of Daphne genkwa induce apoptosis in human myelocytic HL-60 cells and suppress tumor growth in Lewis lung carcinoma (LLC)-inoculated mouse model.
PubMed:
Antitumor activity of daphnodorins from Daphne genkwa roots.
PubMed:
Total flavonoids of Daphne genkwa root significantly inhibit the growth and metastasis of Lewis lung carcinoma in C57BL6 mice.
PubMed:
Structural determination of diterpenes from Daphne genkwa by NMR spectroscopy.
PubMed:
Isolation of flavonoids, a biscoumarin and an amide from the flower buds of Daphne genkwa and the evaluation of their anti-complement activity.
PubMed:
Preparation of yuanhuacine and relative daphne diterpene esters from Daphne genkwa and structure-activity relationship of potent inhibitory activity against DNA topoisomerase I.
PubMed:
Three biflavonoids from ethanol extract of the root of Daphne genkwa.
PubMed:
Isolation and identification of a new dicoumarin from the roots of Daphne genkwa.
PubMed:
Novel diterpenoids with potent inhibitory activity against endothelium cell HMEC and cytotoxic activities from a well-known TCM plant Daphne genkwa.
PubMed:
[Pharmacological effects of Daphne genkwa and Chinese medical prescription, "Jyu-So-To"].
PubMed:
Evaluation of natural products on inhibition of inducible cyclooxygenase (COX-2) and nitric oxide synthase (iNOS) in cultured mouse macrophage cells.
PubMed:
[Comprehensive evaluation and practical confirmation on processing technology of Daphne genkwa Sieb. et Zucc].
PubMed:
[Effects of processing on toxicity and pharmacological action of flos Genkwa].
PubMed:
[Quality of processed samples of Daphne genkwa Sieb. et Zucc].
PubMed:
[HPLC analysis of mimic vinegar-processing of genkwanin].
PubMed:
[Determination of yuanhuacine in Daphne genkwa Sieb. et Zucc. by HPLC].
PubMed:
Screening of Epstein-Barr virus early antigen expression inducers from Chinese medicinal herbs and plants.
PubMed:
[GC-MS analysis of influence of processing on volatile oil in Daphne genkwa Sieb. et Zucc].
PubMed:
[Analysis and comparison of the essential oil from Daphne genkwa Sied. et Zucc. before and after processing by GC-MS].
PubMed:
Some progress on the chemistry of natural bioactive terpenoids from Chinese medicinal plants.
PubMed:
[A new lignanolide from the leaves of Daphne genkwa].
PubMed:
[Chemical studies on the constituents of the thymelaeaceous plants. IV. Structure of a new spiro biflavonoid, genkwanol A, from the root of Daphne genkwa Sieb. et Zucc].
PubMed:
Inhibitors of adenosine 3',5'-cyclic monophosphate phosphodiesterase in Daphne genkwa Sieb. et Zucc.
PubMed:
[Mutagenic evaluation of the Chinese drug C, L, T, G pill consisting of Daphne genkwa, Euphorbia kansui, Euphorbia pekinensis, Glycyrrhiza uralensis tested in Salmonella typhimurium and B. subtilis].
PubMed:
[Determination of hydroxygenkwanin in the leaves of Daphne genkwa].
PubMed:
[Application of orthogonal function spectrophotometry to the determination of total diterpene orthoesters in yuanhua (Daphne genkwa Sieb. et Zucc.) root injection].
PubMed:
Epstein-Barr virus early antigen induction in nasopharyngeal hybrid cells by Chinese medicinal herbs.
PubMed:
[Enhanced transformation of human lymphocytes by Chinese herbs].
PubMed:
Inhibitors of xanthine oxidase from the flowers and buds of Daphne genkwa.
PubMed:
Antitumor agents LVI: the protein synthesis inhibition by genkwadaphnin and yuanhuacine of P-388 lymphocytic leukemia cells.
PubMed:
[STUDIES ON THE FLAVONOIDS PRESENT IN CHINESE DRUGS. XI. THE CHEMICAL COMPOSITION OF THE ROOT BARK OF DAPHNE GENKWA SIEB. ET ZUCC].