dextro,laevo-borneol
borneol
Identification
| Name | dextro,laevo-borneol |
| IUPAC | (1R,2S,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-ol |
| CAS Number | 507-70-0 |
| EINECS | 208-080-0 |
| FDA UNII | M89NIB437X |
| Molecular Formula | C10 H18 O |
| Molecular Weight | 154.25266000 |
| MDL Number | MFCD00066426 |
| Nikkaji Number | J9.305J |
| Beilstein | 2038056 |
| CoE Number | 64 |
| XlogP3 | 2.70 (est) |
Regulatory
| JECFA Food Flavoring | 1385 borneol |
| DG SANTE Food Flavourings | 02.016 borneol |
| FDA Mainterm (SATF) | 507-70-0 ; BORNEOL |
| FDA Regulation | FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION |
Physical Properties
| Appearance | white crystalline powder (est) |
| Assay | 97.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 202.00 to 208.00 °C. @ 760.00 mm Hg |
| Boiling Point | 212.00 to 213.00 °C. @ 760.00 mm Hg, 135.00 to 136.00 °C. @ 50.00 mm Hg |
| Vapor Pressure | 0.035000 mmHg @ 25.00 °C. |
| Flash Point | 150.00 °F. TCC ( 65.56 °C. ) |
| logP (o/w) | 2.690 |
| Soluble in | alcohol |
| Insoluble in | water |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | fragrance |
Organoleptic Properties
| Odor Description | at 10.00 % in dipropylene glycol. |
Safety Information
| Preferred SDS | View |
| European information | Most important hazard(s): |
| Oral/Parenteral Toxicity | oral-rat LD50 500 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | flavor and fragrance agents |
| RIFM Fragrance Material Safety Assessment | Search |
| Recommendation for dextro,laevo-borneol usage levels up to | 3.0000 % in the fragrance concentrate. |
| Maximised Survey-derived Daily Intakes (MSDI-EU) | 130.00 (μg/capita/day) |
| Maximised Survey-derived Daily Intakes (MSDI-USA) | 23.00 (μg/capita/day) |
| Threshold of Concern | 1800 (μg/person/day) |
| Structure Class | I |
| baked goods | - |
| beverages(nonalcoholic) | 0.25000 |
| beverages(alcoholic) | - |
| breakfast cereal | - |
| cheese | - |
| chewing gum | - |
| condiments / relishes | - |
| confectionery froastings | - |
| egg products | - |
| fats / oils | - |
| fish products | - |
| frozen dairy | - |
| fruit ices | - |
| gelatins / puddings | - |
| granulated sugar | - |
| gravies | - |
| hard candy | - |
| imitation dairy | - |
| instant coffee / tea | - |
| jams / jellies | - |
| meat products | - |
| milk products | - |
| nut products | - |
| other grains | - |
| poultry | - |
| processed fruits | - |
| processed vegetables | - |
| reconstituted vegetables | - |
| seasonings / flavors | - |
| snack foods | - |
| soft candy | - |
| soups | - |
| sugar substitutes | - |
| sweet sauces | - |
Advanced Biotech. Inc.
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Foreverest Resources Ltd.
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Supplying turpentine based and natural/extracted flavor & fragrance ingredients.
Indukern, S.A. F&F Ingredients Division
Commitment to quality
Idukern F&F Ingredients is your partner for the fragrance and flavor ingredients.
Lluch Essence S.L.
A family company dedicated to sales and distribution
Flexibility, availability, price and quality.
M&U International LLC
Steady supply & demand
Meeting customers increasing demands at home as well as abroad.
Penta International Corporation
Chemistry innovation
At Penta, our products and services help businesses do business better.
Prodasynth
PRODUCTEUR PAR ESSENCE
Chemical specialist in manufacturing, distributing and sourcing of tailor-made ingredients for the Flavour & Fragrance industry.
The John D. Walsh Company, Inc
Suppliers Since 1942
Supplying the fragrance and flavor industry with high quality products.
The Lermond Company
Your Sourcing Resource
The Lermond family has been sourcing raw materials for the flavor and fragrance industry for nearly 7 decades.
Potential Uses
Natural Occurrence
Synonyms
bicyclo(2.2.1)heptan-2-ol, 1,7,7-trimethyl-, (1R,2S,4R)-rel-
bicyclo[2.2.1]heptan-2-ol, 1,7,7-trimethyl-, (1R,2S,4R)-
borneol
(1R,2S,4R)-
borneol
dextro,laevo-
borneol
DL-
borneol
N-
borneol
borneol 60/40
borneol crystals
borneol flakes
borneol natural
bhimsaim
camphor
borneo
camphor
dextro,laevo-1,7,7-
trimethyl bicyclo(2.2.1)heptan-2-ol
DL-1,7,7-
trimethyl bicyclo(2.2.1)heptan-2-ol
(1R-endo)-1,7,7-
trimethylbicyclo(2.2.1)heptan-2-ol
(1R,2S,4R)-rel-1,7,7-
trimethylbicyclo(2.2.1)heptan-2-ol
(1R-endo)-1,7,7-
trimethylbicyclo[2.2.1]heptan-2-ol
(1R,2S,4R)-1,7,7-
trimethylbicyclo[2.2.1]heptan-2-ol
PubMed:
Phytochemical study of Cistus libanotis L.
PubMed:
Synergistic apoptosis-inducing effects on A375 human melanoma cells of natural borneol and curcumin.
PubMed:
Assessment of antioxidative, chelating, and DNA-protective effects of selected essential oil components (eugenol, carvacrol, thymol, borneol, eucalyptol) of plants and intact Rosmarinus officinalis oil.
PubMed:
Phytochemical and physical-chemical analysis of Polish willow (Salix spp.) honey: identification of the marker compounds.
PubMed:
Mechanical, rheological and release behaviors of a poloxamer 407/ poloxamer 188/carbopol 940 thermosensitive composite hydrogel.
PubMed:
Natural borneol, a monoterpenoid compound, potentiates selenocystine-induced apoptosis in human hepatocellular carcinoma cells by enhancement of cellular uptake and activation of ROS-mediated DNA damage.
PubMed:
Identification of 1,8-cineole, borneol, camphor, and thujone as anti-inflammatory compounds in a Salvia officinalis L. infusion using human gingival fibroblasts.
PubMed:
Chemical composition and anticancer activity of essential oils of Mediterranean sage (Salvia officinalis L.) grown in different environmental conditions.
PubMed:
Chemical composition, antimicrobial, cytotoxic and antioxidant activities of the essential oil of Artemisia indica Willd.
PubMed:
Synergistic combinations of high hydrostatic pressure and essential oils or their constituents and their use in preservation of fruit juices.
PubMed:
Borneol alleviates oxidative stress via upregulation of Nrf2 and Bcl-2 in SH-SY5Y cells.
PubMed:
Volatiles of Chrysanthemum zawadskii var. latilobum K.
PubMed:
Inhibition of morphine glucuronidation in the liver microsomes of rats and humans by monoterpenoid alcohols.
PubMed:
Synthesis, acute toxicity and anti-inflammatory effect of bornyl salicylate, a salicylic acid derivative.
PubMed:
Preparation of natural borneol/2-hydroxypropyl-β-cyclodextrin inclusion complex and its effect on the absorption of tetramethylpyrazine phosphate in mouse.
PubMed:
Velamo do campo: its volatile constituents, secretory elements, and biological activity.
PubMed:
Formation of β-cyclodextrin inclusion enhances the stability and aqueous solubility of natural borneol.
PubMed:
Antimicrobial Activity and Chemical Composition of Essential Oil From the Seeds of Artemisia aucheri Boiss.
PubMed:
Selective extraction of oxygenated compounds from oregano with sub-critical water.
PubMed:
Antibacterial activity and GC/MS analysis of the essential oils from flower, leaf and stem of Origanum vulgare ssp. viride growing wild in north-west Iran.
PubMed:
Chemical composition and antimicrobial activity of Satureja kitaibelii essential oil against pathogenic microbial strains.
PubMed:
Development of quality assessment method for optically active food flavor chemicals.
PubMed:
Chemical composition and larvicidal effects of essential oil of Blumea martiniana against Anopheles anthropophagus.
PubMed:
Chemical composition and antimicrobial activity of essential oils of Thymus algeriensis, Eucalyptus globulus and Rosmarinus officinalis from Morocco.
PubMed:
Chemical composition and larvicidal activity of Blumea densiflora essential oils against Anopheles anthropophagus: a malarial vector mosquito.
PubMed:
Essential oil composition and antioxidant and antimicrobial properties of the aerial parts of Salvia eremophila Boiss. from Iran.
PubMed:
Chemical composition of hydrodistilled essential oil of Artemisia incana (L.) Druce and antimicrobial activity against foodborne microorganisms.
PubMed:
Chemical composition and antimicrobial and antioxidant activities of Mentha (longifolia L. and viridis) essential oils.
PubMed:
Investigation of anti-oxidative, cytotoxic, DNA-damaging and DNA-protective effects of plant volatiles eugenol and borneol in human-derived HepG2, Caco-2 and VH10 cell lines.
PubMed:
Antimicrobial activity of the essential oil obtained from roots and chemical composition of the volatile constituents from the roots, stems, and leaves of Ballota nigra from Serbia.
PubMed:
Chemical composition, antibacterial and antioxidant activities of leaf essential oil and extracts of Metasequioa glyptostroboides Miki ex Hu.
PubMed:
Chemical and biomolecular characterization of Artemisia umbelliformis Lam., an important ingredient of the alpine liqueur "Genepi".
PubMed:
Effects of borneol on the level of DNA damage induced in primary rat hepatocytes and testicular cells by hydrogen peroxide.
PubMed:
Influence of borneol on primary mice oral fibroblasts: a penetration enhancer may be used in oral submucous fibrosis.
PubMed:
Fragrance material review on l-borneol.
PubMed:
Fragrance material review on borneol.
PubMed:
The monoterpenoids citral and geraniol are moderate inhibitors of CYP2B6 hydroxylase activity.
PubMed:
Tunisian Salvia officinalis L. and Schinus molle L. essential oils: their chemical compositions and their preservative effects against Salmonella inoculated in minced beef meat.
PubMed:
Inhibition of 7,12-dimethylbenz[a]anthracene induced mouse skin carcinogenesis by Artemisia capillaris.
PubMed:
Screening of antibacterial activities of twenty-one oxygenated monoterpenes.
PubMed:
Bismuth subgallate/borneol (suile) is superior to bacitracin in the human forearm biopsy model for acute wound healing.
PubMed:
Chemical composition and antifungal activity of Salvia macrochlamys and Salvia recognita essential oils.
PubMed:
Composition, enantiomeric distribution, and antibacterial activity of the essential oil of Achillea ligustica All. from Corsica.
PubMed:
Supercritical carbon dioxide extraction of compounds with antimicrobial activity from Origanum vulgare L.: determination of optimal extraction parameters.
PubMed:
Chemical composition and antioxidant, antimicrobial, and antifungal activities of the essential oil of Achillea ligustica all.
PubMed:
Effects of antimicrobial components of essential oils on growth of Bacillus cereus INRA L2104 in and the sensory qualities of carrot broth.
PubMed:
Isolation of antioxidant compounds from the methanolic extract of the roots of Decalepis hamiltonii (Wight and Arn.).
PubMed:
Harvest regimen optimization and essential oil production in five tansy (Tanacetum vulgare L.) genotypes under a northern climate.
PubMed:
Chemical composition and antimicrobial activity of Rosmarinus officinalis L. essential oil obtained via supercritical fluid extraction.
PubMed:
[Measurement of borneol based on near infrared spectroscopy].
PubMed:
Screening of chemical composition and antifungal and antioxidant activities of the essential oils from three Turkish artemisia species.
PubMed:
The effect of applying a pipe-joint lubricant to connect ductile iron pipe on off-flavors in drinking water distribution systems.
PubMed:
chemical composition, plant genetic differences, antimicrobial and antifungal activity investigation of the essential oil of Rosmarinus officinalis L.
PubMed:
Analysis of the essential oils of the leaves, stems, rhizomes and roots of the medicinal plant Alpinia galanga from southern India.
PubMed:
Essential oils from Mediterranean lamiaceae as weed germination inhibitors.
PubMed:
Chemical composition and in vitro evaluation of antioxidant effect of free volatile compounds from Satureja montana L.
PubMed:
High-affinity monoclonal antibodies for detection of the microbial metabolite, 2-methylisoborneol.
PubMed:
Common herbs, essential oils, and monoterpenes potently modulate bone metabolism.
PubMed:
Bacterial susceptibility to and chemical composition of essential oils from Thymus kotschyanus and Thymus persicus.
PubMed:
Fungicidal property of Curcuma longa L. rhizome-derived curcumin against phytopathogenic fungi in a greenhouse.
PubMed:
Antimicrobial and antioxidant activity of the essential oil and methanol extracts of Thymus pectinatus Fisch. et Mey. Var. pectinatus (Lamiaceae).
PubMed:
Attractiveness of 79 compounds and mixtures to wild Ceratitis capitata (Diptera: Tephritidae) in field trials.
PubMed:
Composition and antimicrobial activity of the essential oils of Micromeria cristata subsp. phrygia and the enantiomeric distribution of borneol.
PubMed:
Production of yarrow (Achillea millefolium L.) in Norway: essential oil content and quality.
PubMed:
Volatile chemicals identified in extracts from leaves of Japanese mugwort (Artemisia princeps pamp.).
PubMed:
[Stereochemical structure of d-borneol in "the Japanese Standards of Food Additives"].
PubMed:
Cloning and expression of a rat liver phenobarbital-inducible UDP-glucuronosyltransferase (2B12) with specificity for monoterpenoid alcohols.
PubMed:
Mutagenicity and antimutagenicity testing of six chemicals associated with the pungent properties of specific spices as revealed by the Ames Salmonella/microsomal assay.