ectoin
1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid
Identification
| Name | ectoin |
| IUPAC | (6S)-2-methyl-1,4,5,6-tetrahydropyrimidine-6-carboxylic acid |
| CAS Number | 96702-03-3 |
| FDA UNII | 7GXZ3858RY |
| Molecular Formula | C6 H10 N2 O2 |
| Molecular Weight | 142.15810000 |
| MDL Number | MFCD03419286 |
| Nikkaji Number | J659.626F |
| Beilstein | 7288977 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 2.048e+004 mg/L @ 25 °C (est) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | skin conditioning |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | cosmetic ingredient for skin conditioning |
| Recommendation for ectoin usage levels up to | not for fragrance use. |
| Recommendation for ectoin flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
(6S)-2-
methyl-1,4,5,6-tetrahydropyrimidine-6-carboxylic acid
4-
pyrimidinecarboxylic acid, 1,4,5,6,-tetrahydro-2-methyl-, (4S)-
1,4,5,6-
tetrahydro-2-methyl-4-pyrimidinecarboxylic acid
Google Patents:
Ectoin and ectoin derivatives as moisturizers in cosmetics
PubMed:
Reduction of neutrophilic lung inflammation by inhalation of the compatible solute ectoine: a randomized trial with elderly individuals.
PubMed:
Serum-free non-toxic freezing solution for cryopreservation of human adipose tissue-derived mesenchymal stem cells.
PubMed:
Actinobacteria from Arid and Desert Habitats: Diversity and Biological Activity.
PubMed:
Genomic analysis of the nitrate-respiring Sphingopyxis granuli (formerly Sphingomonas macrogoltabida) strain TFA.
PubMed:
Cryopreservation of hMSCs seeded silk nanofibers based tissue engineered constructs.
PubMed:
Challenges to design and develop of DNA aptamers for protein targets. I. Optimization of asymmetric PCR for generation of a single stranded DNA library.
PubMed:
Stability of lysozyme in aqueous extremolyte solutions during heat shock and accelerated thermal conditions.
PubMed:
Effects of non-toxic cryoprotective agents on the viability of cord blood derived MNCs.
PubMed:
The active natural anti-oxidant properties of chamomile, milk thistle, and halophilic bacterial components in human skin in vitro.
PubMed:
[Production and characterization of Methylomicrobium alcaliphilum 20Z knockout mutants, which has sucrose and ectoin synthesis defective genes].
PubMed:
A prospective, controlled study of SNS01 (ectoine nasal spray) compared to BNO-101 (phytotherapeutic dragées) in patients with acute rhinosinusitis.
PubMed:
Video analysis of osmotic cell response during cryopreservation.
PubMed:
Systematic parameter optimization of a Me(2)SO- and serum-free cryopreservation protocol for human mesenchymal stem cells.
PubMed:
Alternatives to dimethylsulfoxide for serum-free cryopreservation of human mesenchymal stem cells.
PubMed:
[Biosynthesis of the bioprotectant ectoin by aerobic methylotrophic bacteria from methanol].
PubMed:
The compatible solute ectoine protects against nanoparticle-induced neutrophilic lung inflammation.
PubMed:
Genotoxicity of visible light (400-800 nm) and photoprotection assessment of ectoin, L-ergothioneine and mannitol and four sunscreens.
PubMed:
In vivo assessment of Ectoin: a randomized, vehicle-controlled clinical trial.
PubMed:
[Vitamin B12-independent strains of Methylophaga marina isolated from Red Sea algae].
PubMed:
Screening of novel excipients for improving the stability of retroviral and adenoviral vectors.
PubMed:
[Biotechnological potential of methylotrophic bacteria: a review of current status and future prospects].
PubMed:
Ectoin: an effective natural substance to prevent UVA-induced premature photoaging.
PubMed:
Detection of ectoin biosynthesis genes in halotolerant aerobic methylotrophic bacteria.