Potential Uses
buffering agents
Natural Occurrence
alfalfa
apple plant
apricot fruit
asparagus shoot
banana fruit
banana leaf
basil plant
bean black bean fruit
bean field bean fruit
beer
PMC
bilberry leaf
broccoli asparagus broccoli plant
brussel sprout leaf
buckthorn sea buckthorn fruit
cabbage leaf
carrot root
celery root
cheese swiss cheese @ 4.00 ± 1 mmol
Data
cherry sour cherry fruit
chive leaf
coconut root
coconut seed
corn plant
corn seed
currant red currant fruit
fig fruit
fig fruit juice
garlic plant
ginkgo biloba leaf
ginkgo biloba pollen
grape fruit
kiwi plant
lemon balm plant
lime fruit
loquat fruit
lupine white lupine seed
mango fruit
onion bulb
onion leaf
orange fruit
orange fruit juice
parsley plant
parsley root
pea seed
pistachio nut
plum fruit
pomegranate fruit
poppy opium poppy latex
potato plant
raspberry red raspberry fruit
raspberry red raspberry fruit, leaf
raspberry red raspberry leaf
rhubarb plant
soybean root
soybean seed
soybean sprout
star fruit fruit
sunflower leaf
tamarind fruit
tamarind seed
tomatillo fruit
tomato fruit
Synonyms
acidum succinicum
amber acid
asuccin
bernsteinsaure
butane dioic acid
1,4-
butane dioic acid
butane dionic acid
butanedioic acid
1,4-
butanedioic acid
dihydrofumaric acid
1,2-
ethane dicarboxylic acid
1,2-
ethanedicarboxylic acid
ethylene dicarboxylic acid
ethylene succinic acid
katasuccin
spirit of amber
bio-
succinic acid
succinic acid FCC
succinic acid N.F. grade
succinic acid natural
succinic acid synthetic
succinic acid technical grade
succinicacid
wormwood acid
Perfumer & Flavorist:
Organoleptic Characteristics of Flavor Materials
PubMed:
Integration of metabolomics and subcellular organelle expression microarray to increase understanding the organic acid changes in post-harvest citrus fruit.
Leffingwell & Associates:
Flavor Properties of FEMA GRAS List 25 flavor chemicals
PubMed:
Robust nanobioconjugates of Candida antarctica lipase B--multiwalled carbon nanotubes: characterization and application for multiple usages in non-aqueous biocatalysis.
PubMed:
Metabolic fingerprinting of hard and semi-hard natural cheeses using gas chromatography with flame ionization detector for practical sensory prediction modeling.
PubMed:
Identification and analysis of the metabolic functions of a high-salt-tolerant halophilic aromatic yeast Candida etchellsii for soy sauce production.
PubMed:
Oxygen consumption rate of permeabilized cells and isolated mitochondria from pork M. masseter and liver examined fresh and after freeze-thawing at different pH values.
PubMed:
Nonvolatile taste compounds in cooked Chinese Nanjing duck meat following postproduction heat treatment.
PubMed:
Metabolomics-based component profiling of hard and semi-hard natural cheeses with gas chromatography/time-of-flight-mass spectrometry, and its application to sensory predictive modeling.
PubMed:
Sources of umami taste in Cheddar and Swiss cheeses.
PubMed:
Development of a CE method to analyze organic acids in dairy products: application to study the metabolism of heat-shocked spores.
PubMed:
A hybrid of ant colony optimization and minimization of metabolic adjustment to improve the production of succinic acid in Escherichia coli.
PubMed:
Anaerobic organic acid metabolism of Candida zemplinina in comparison with Saccharomyces wine yeasts.
PubMed:
Development of an industrializable fermentation process for propionic acid production.
PubMed:
Evolution of polyphenols and organic acids during the fermentation of apple cider.
PubMed:
Physicochemical and Microbial Properties of the Korean Traditional Rice Wine, Makgeolli, Supplemented with Banana during Fermentation.
PubMed:
[Progress in microbial production of succinic acid].
PubMed:
Valorization of industrial waste and by-product streams via fermentation for the production of chemicals and biopolymers.
PubMed:
Succinic acid in levels produced by yeast (Saccharomyces cerevisiae) during fermentation strongly impacts wheat bread dough properties.
PubMed:
Recent advances in production of succinic acid from lignocellulosic biomass.
PubMed:
High-fat diet reduces the formation of butyrate, but increases succinate, inflammation, liver fat and cholesterol in rats, while dietary fibre counteracts these effects.
PubMed:
Microbiological Characteristics of Wild Yeast Strain Pichia anomala Y197-13 for Brewing Makgeolli.
PubMed:
Contributions of citrate in redox potential maintenance and ATP production: metabolic pathways and their regulation in Lactobacillus panis PM1.
PubMed:
Metabolic engineering of Escherichia coli to minimize byproduct formate and improving succinate productivity through increasing NADH availability by heterologous expression of NAD(+)-dependent formate dehydrogenase.
PubMed:
Stability of monacolin K and citrinin and biochemical characterization of red-koji vinegar during fermentation.
PubMed:
Quality of tomato slices disinfected with ozonated water.
PubMed:
Microbial succession and metabolite changes during long-term storage of Kimchi.
PubMed:
Comparative proteomic and metabolomic profiling of citrus fruit with enhancement of disease resistance by postharvest heat treatment.
PubMed:
Influence of oxygen on NADH recycling and oxidative stress resistance systems in Lactobacillus panis PM1.
PubMed:
Wheat flour based propionic acid fermentation: an economic approach.
PubMed:
Effects of succinate and pH on cooked beef color.
PubMed:
Evaluation of certain food additives and contaminants.
PubMed:
Analysis of Taiwan patents for the medicinal mushroom "Niu-Chang- Chih".
PubMed:
Physico-chemical and antioxidant properties of four mango (Mangifera indica L.) cultivars in China.
PubMed:
(-) Epicatechin attenuates mitochondrial damage by enhancing mitochondrial multi-marker enzymes, adenosine triphosphate and lowering calcium in isoproterenol induced myocardial infarcted rats.
PubMed:
The genetic basis of natural variation in oenological traits in Saccharomyces cerevisiae.
PubMed:
Mapping of Saccharomyces cerevisiae metabolites in fermenting wheat straight-dough reveals succinic acid as pH-determining factor.
PubMed:
Isolation and characterization of novel 1,3-propanediol-producing Lactobacillus panis PM1 from bioethanol thin stillage.
PubMed:
Textural characteristic, antioxidant activity, sugar, organic acid, and phenolic profiles of 10 promising jujube (Ziziphus jujuba Mill.) selections.
PubMed:
Metabolic fingerprinting of hard and semi-hard natural cheeses using gas chromatography with flame ionization detector for practical sensory prediction modeling.
PubMed:
Role of anionic charges of periplasmic glucans of Shigella flexneri in overcoming detergent stress.
PubMed:
Identification of organic acids in wine that stimulate mechanisms of gastric acid secretion.
PubMed:
A metabolomic approach to the study of wine micro-oxygenation.
PubMed:
Review of biological and pharmacological activities of the endemic Taiwanese bitter medicinal mushroom, Antrodia camphorata (M. Zang et C. H. Su) Sh. H. Wu et al. (higher Basidiomycetes).
PubMed:
High level production of 5-aminolevulinic acid by Propionibacterium acidipropionici grown in a low-cost medium.
PubMed:
Metabolic profiling of Staphylococcus aureus cultivated under aerobic and anaerobic conditions with (1)H NMR-based nontargeted analysis.
PubMed:
Metabolomics-based component profiling of hard and semi-hard natural cheeses with gas chromatography/time-of-flight-mass spectrometry, and its application to sensory predictive modeling.
PubMed:
Field enhancement sample stacking for analysis of organic acids in traditional Chinese medicine by capillary electrophoresis.
PubMed:
The effect of once daily omeprazole and succinic acid (VECAM) vs once daily omeprazole on 24-h intragastric pH.
PubMed:
In vitro and in vivo characterization of amorphous, nanocrystalline, and crystalline ziprasidone formulations.
PubMed:
Genes involved in lactose catabolism and organic acid production during growth of Lactobacillus delbrueckii UFV H2b20 in skimmed milk.
PubMed:
Identification of beer bitter acids regulating mechanisms of gastric acid secretion.
PubMed:
Microbial production of propionic acid from propionibacteria: current state, challenges and perspectives.
PubMed:
Role of anionic charges of osmoregulated periplasmic glucans of Salmonella enterica serovar Typhimurium SL1344 in mice virulence.
PubMed:
Integrated separation process for isolation and purification of biosuccinic acid.
PubMed:
Proteomic analysis on acetate metabolism in Citrobacter sp. BL-4.
PubMed:
Preparation and characterization of succinic acid deamidated wheat gluten microspheres for encapsulation of fish oil.
PubMed:
Influence of dietary blueberry and broccoli on cecal microbiota activity and colon morphology in mdr1a(-/-) mice, a model of inflammatory bowel diseases.
PubMed:
Effects of freeze-drying of samples on metabolite levels in metabolome analyses.
PubMed:
Rapid NMR method for the quantification of organic compounds in thin stillage.
PubMed:
[Phenotropyl succinate as the means for correction of neuroimmune disturbances under conditions of informational-physical stress].
PubMed:
Purification of d-a-tocopheryl polyethylene glycol 1000 succinate (TPGS) by a temperature-modulated silica gel column chromatography: use of Taguchi method to optimize purification conditions.
PubMed:
Transcellular transport of domoic acid across intestinal Caco-2 cell monolayers.
PubMed:
Effects of pyruvate, succinate, and lactate enhancement on beef longissimus raw color.
PubMed:
Sensorically and antimicrobially active metabolite production of Lactobacillus strains on Jerusalem artichoke juice.
PubMed:
Evaluation of certain food additives and contaminants.
PubMed:
Designing carbohydrate nanoparticles for prolonged efficacy of antimicrobial peptide.
PubMed:
Evaluation of certain food additives. Seventy-first report of the Joint FAO/WHO Expert Committee on Food Additives.
PubMed:
Metabolite profiling of Cheonggukjang, a fermented soybean paste, inoculated with various Bacillus strains during fermentation.
PubMed:
Effect of pH, aeration and feeding non-sterilized agave juice in a continuous agave juice fermentation.
PubMed:
Determination of non-volatile and volatile organic acids in Korean traditional fermented soybean paste (Doenjang).
PubMed:
Use of response surface methodology in a fed-batch process for optimization of tricarboxylic acid cycle intermediates to achieve high levels of canthaxanthin from Dietzia natronolimnaea HS-1.
PubMed:
Global regulation of food supply by Pseudomonas putida DOT-T1E.
PubMed:
Metabolomics analysis reveals the compositional differences of shade grown tea (Camellia sinensis L.).
PubMed:
A portable photoelectrochemical probe for rapid determination of chemical oxygen demand in wastewaters.
PubMed:
Cereal-based biorefinery development: utilisation of wheat milling by-products for the production of succinic acid.
PubMed:
Effect of succinate sodium on the metmyoglobin reduction and color stability of beef patties.
PubMed:
A thorough study on the use of quantitative 1H NMR in Rioja red wine fermentation processes.
PubMed:
Characterization of low-molecular-weight antiyeast metabolites produced by a food-protective Lactobacillus-Propionibacterium coculture.
PubMed:
Screening and selection of marine isolate for L-glutaminase production and media optimization using response surface methodology.
PubMed:
[Breeding of Actinobacillus succiniogenes mutants with improved succinate production based on metabolic flux analysis].
PubMed:
Niuchangchih (Antrodia camphorata) and its potential in treating liver diseases.
PubMed:
[Screening, breeding and metabolic analysis of a succinic-acid-producing strain].
PubMed:
A succinate-based composition reverses menopausal symptoms without sex hormone replacement therapy.
PubMed:
Use of dicarboxylic acids to improve and diversify the material properties of porous chitosan membranes.
PubMed:
Quantitative reconstruction of the nonvolatile sensometabolome of a red wine.
PubMed:
Succinic acid production from cheese whey using Actinobacillus succinogenes 130 Z.
PubMed:
Comparison of the skin sensitizing potential of unsaturated compounds as assessed by the murine local lymph node assay (LLNA) and the guinea pig maximization test (GPMT).
PubMed:
Determination of differences in the nonvolatile metabolites of pine-mushrooms (Tricholoma matsutake Sing.) according to different parts and heating times using 1H NMR and principal component analysis.
PubMed:
Sources of umami taste in Cheddar and Swiss cheeses.
PubMed:
Bioconversion of tyrosol into hydroxytyrosol and 3,4-dihydroxyphenylacetic acid under hypersaline conditions by the new Halomonas sp. strain HTB24.
PubMed:
Bacterial synthesis of poly(hydroxybutyrate- co-hydroxyvalerate) using carbohydrate-rich mahua (Madhuca sp.) flowers.
PubMed:
Population dynamics and metabolite target analysis of lactic acid bacteria during laboratory fermentations of wheat and spelt sourdoughs.
PubMed:
In situ measurements of pH changes in beta-lactoglobulin solutions under high hydrostatic pressure.
PubMed:
A convenient route to the synthesis of isotopomeric dihydro-2(3H)furanones.
PubMed:
[Simultaneous determination of twenty-one organic acids in food by ion chromatography with eluent autogeneration].
PubMed:
Ion chromatographic determination of organic acids in food samples using a permanent coating graphite carbon column.
PubMed:
High-throughput microplate enzymatic assays for fast sugar and acid quantification in apple and tomato.
PubMed:
Profiling the chlorogenic acids and other caffeic acid derivatives of herbal chrysanthemum by LC-MSn.
PubMed:
Cholesterol hemisuccinate: a selective inhibitor of family X DNA polymerases.
PubMed:
Profiling the chlorogenic acids of aster by HPLC-MS(n).
PubMed:
Bifidobacterium infantis strains with and without a combination of oligofructose and inulin (OFI) attenuate inflammation in DSS-induced colitis in rats.
PubMed:
Metabolomic discrimination of different grades of pine-mushroom (Tricholoma matsutake Sing.) using 1H NMR spectrometry and multivariate data analysis.
PubMed:
Lactobacillus casei metabolic potential to utilize citrate as an energy source in ripening cheese: a bioinformatics approach.
PubMed:
Kinetic analysis of bifidobacterial metabolism reveals a minor role for succinic acid in the regeneration of NAD+ through its growth-associated production.
PubMed:
Use of Rhodotorula minuta live cells hosted in water-in-oil macroemulsion for biotrasformation reaction.
PubMed:
Quantitative studies, taste reconstitution, and omission experiments on the key taste compounds in morel mushrooms (Morchella deliciosa Fr.).
PubMed:
Molecular and sensory studies on the umami taste of Japanese green tea.
PubMed:
Growth of Campylobacter in media supplemented with organic acids.
PubMed:
Effect of gene disruptions of the TCA cycle on production of succinic acid in Saccharomyces cerevisiae.
PubMed:
Rapid determination of short-chain fatty acids in colonic contents and faeces of humans and rats by acidified water-extraction and direct-injection gas chromatography.
PubMed:
Effects of succinylation on the structure and thermostability of lysozyme.
PubMed:
Metabolic adaptations of liver mitochondria during restricted feeding schedules.
PubMed:
Activity-guided identification of (S)-malic acid 1-O-D-glucopyranoside (morelid) and gamma-aminobutyric acid as contributors to umami taste and mouth-drying oral sensation of morel mushrooms (Morchella deliciosa Fr.).
PubMed:
Succinate production and citrate catabolism by Cheddar cheese nonstarter lactobacilli.
PubMed:
A sphingolipid and tyrosinase inhibitors from the fruiting body of Phellinus linteus.
PubMed:
Intra-oral acid production associated with eating whole or pulped raw fruits.
PubMed:
c-Jun N-terminal kinase is required for vitamin E succinate-induced apoptosis in human gastric cancer cells.
PubMed:
Food restriction affects energy metabolism in rat liver mitochondria.
PubMed:
Combined impact of pH and organic acids on iron uptake by Caco-2 cells.
PubMed:
Anxiolytic-like effect of succinic acid in mice.
PubMed:
Energy metabolism and valve closure behaviour in the Asian clam Corbicula fluminea.
PubMed:
A pilot study to investigate effects of inulin on Caco-2 cells through in vitro metabolic fingerprinting.
PubMed:
Skeletal muscle mitochondrial oxidative capacity and uncoupling protein 3 are differently influenced by semistarvation and refeeding.
PubMed:
NTP Toxicology and Carcinogenesis Studies of Tetrahydrofuran (CAS No. 109-99-9) in F344/N Rats and B6C3F1 Mice (Inhalation Studies).
PubMed:
Effect of organic acids and nitrogen source on alcoholic fermentation: study of their buffering capacity.
PubMed:
Roles of Fas signaling pathway in vitamin E succinate-induced apoptosis in human gastric cancer SGC-7901 cells.
PubMed:
Organic acids influence iron uptake in the human epithelial cell line Caco-2.
PubMed:
Development of a CE method to analyze organic acids in dairy products: application to study the metabolism of heat-shocked spores.
PubMed:
RRR-alpha-tocopheryl succinate inhibits human gastric cancer SGC-7901 cell growth by inducing apoptosis and DNA synthesis arrest.
PubMed:
Inhibitory effects of RRR-alpha-tocopheryl succinate on benzo(a)pyrene (B(a)P)-induced forestomach carcinogenesis in female mice.
PubMed:
Potent enantioselective auxin: indole-3-succinic acid.
PubMed:
Characterization of cigar tobaccos by gas chromatographic/mass spectrometric analysis of nonvolatile organic acids: application to the authentication of Cuban cigars.
PubMed:
Comparative study on chemical changes in olive juice and brine during green olive fermentation.
PubMed:
Potentiation of the insulinotropic action of GLP-1 by succinic acid dimethyl ester in fed anaesthetized rats.
PubMed:
Effects of the dimethyl ester on succinic acid on the hormonal and metabolic response to exercise in hereditarily diabetic starved rats.
PubMed:
Changes in gamma-aminobutyric acid content during beni-koji making.
PubMed:
Anaerobiosis in the nematode Caenorhabditis elegans.
PubMed:
Production of multifunctional organic acids from renewable resources.
PubMed:
Assessment of the nutritional value of glycerol-1,2, 3-tris(methylsuccinate) in fed and starved rats.
PubMed:
Ubiquinol:cytochrome c oxidoreductase. Effects of inhibitors on reverse electron transfer from the iron-sulfur protein to cytochrome b.
PubMed:
Simultaneous quantification of released succinic acid and a weakly basic drug compound in dissolution media.
PubMed:
Influence of culture conditions on biofilm formation by Escherichia coli O157:H7.
PubMed:
[The correction of disorders of the internal body environment in animals and man by the addition of succinic acid to food].
PubMed:
Octenylsuccinic aciduria in children fed protein-hydrolysate formulas containing modified cornstarch.
PubMed:
Simultaneous saccharification and fermentation of cellulose to lactic acid.
PubMed:
Lack of toxicity/carcinogenicity of monosodium succinate in F344 rats.
PubMed:
NTP Toxicology and Carcinogenesis Studies of Succinic Anhydride (CAS No. 108-30-5) in F344/N Rats and B6C3F1 Mice (Gavage Studies).
PubMed:
[Functional properties of isolated kidney mitochondria of rats in food deprivation].
PubMed:
Phosphoglycerol substituents present on the cyclic beta-1,2-glucans of Rhizobium meliloti 1021 are derived from phosphatidylglycerol.
PubMed:
Decontamination of Campylobacter jejuni on chicken drumsticks using chemicals and radiation.
PubMed:
[Detection of anion residues of surface-active compounds of the type sulfosuccinic acid salts and succinic acid monoesters on the surface of containers in contact with food].
PubMed:
The destruction of Salmonella typhimurium in chicken exudate by different freeze-thaw treatments.
PubMed:
Simultaneous gas chromatographic determination of carboxylic acids in soft drinks and jams.
PubMed:
Immobilization of fumarase by entrapment of rat liver mitochondria in polyacrylamide gel using gamma rays.
PubMed:
Special bacterial polysaccharides and polysaccharases.
PubMed:
Depressed growth of Morris hepatomas in altitude- and heat-stressed but not in cold-stressed buffalo rats.
PubMed:
[Breeding of a biotype of Myzus persicae sulzer on a synthetic medium. V- Influence of oxalic and gentisic acids on the nutritive value of a synthetic medium].
PubMed:
Lactic and succinic acid levels and refractive indices in the determinations of the age of eggs.
PubMed:
2,4-D metabolism: enzymatic conversion of chloromaleylacetic acid to succinic acid.