butyric anhydride

butanoic acid 1-oxobutyl ester

CAS: 106-31-0 C8 H14 O3 MW: 158.19718000

Identification

Namebutyric anhydride
CAS Number106-31-0
EINECS203-383-4
FDA UNIIA88LE742VX
Molecular FormulaC8 H14 O3
Molecular Weight158.19718000
MDL NumberMFCD00009389
Nikkaji NumberJ5.050D
Beilstein1099474

Regulatory

DG SANTE Food Contact Materialsbutyric anhydride

Physical Properties

Appearance colorless clear liquid (est)
Assay 98.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 0.96700 to 0.97200 @ 25.00 °C.
Pounds per Gallon - (est). 8.046 to 8.088
Refractive Index 1.41050 to 1.41300 @ 20.00 °C.
Melting Point -75.00 to -66.00 °C. @ 760.00 mm Hg
Boiling Point 195.00 to 196.00 °C. @ 760.00 mm Hg
Vapor Pressure 0.283000 mmHg @ 25.00 °C.
Vapor Density 5.45 ( Air = 1 )
Flash Point 180.00 °F. TCC ( 82.00 °C. )
logP (o/w) 1.390
Storage store under nitrogen.
Soluble in alcohol
Insoluble in water

Organoleptic Properties

Odor Description butter

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Oral/Parenteral Toxicityoral-rat LD50 8790 mg/kg
Dermal ToxicityNot determined
Inhalation Toxicityinhalation-mouse LC > 50 mg/m3

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryindirect food additives: adhesives and components of coatings
Recommendation for butyric anhydride usage levels up tonot for fragrance use.
Recommendation for butyric anhydride flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

butanoic acid 1-oxobutyl ester butanoic acid, anhydride butanoic anhydride butanoyl butanoate butyric acid anhydride N- butyric acid anhydride N- butyric anhydride butyricanhydride butyryl oxide PubMed: Dibutyrylchitin nanoparticles as novel drug carrier. PubMed: Synthesis and Characterization of a Novel Phenolic Lipid for Use as Potential Lipophilic Antioxidant and as a Prodrug of Butyric Acid. PubMed: The role of interchain disulfide bond in a recombinant human interleukin-17A variant. PubMed: QSAR, docking, dynamic simulation and quantum mechanics studies to explore the recognition properties of cholinesterase binding sites. PubMed: Acylation of cellulose in a novel solvent system: solution of dibenzyldimethylammonium fluoride in DMSO. PubMed: Synthesis and hypoglycemic activity of esterified-derivatives of mangiferin. PubMed: Synthesis, guest-binding, and reduction-responsive degradation properties of water-soluble cyclophanes having disulfide moieties. PubMed: 4-(4-Iodo-anilino)-2-methyl-ene-4-oxo-butanoic acid. PubMed: Kinetics and mechanism of imidazole-catalyzed acylation of cellulose in LiCl/N,N-dimethylacetamide. PubMed: Selective biocatalytic acylation studies on 5'-O-(4,4'-dimethoxytrityl)-2',3'-secouridine: an efficient synthesis of UNA monomer. PubMed: Evaluation of dibutyrylchitin as new excipient for sustained drug release. PubMed: Anti-proliferative effects of O-acyl-low-molecular-weight heparin derivatives on bovine pulmonary artery smooth muscle cells. PubMed: Thiol-yne and thiol-ene "click" chemistry as a tool for a variety of platinum drug delivery carriers, from statistical copolymers to crosslinked micelles. PubMed: Antitumor effect of butanoylated heparin with low anticoagulant activity on lung cancer growth in mice and rats. PubMed: Application of 1-allyl-3-(1-butyl)imidazolium chloride in the synthesis of cellulose esters: properties of the ionic liquid, and comparison with other solvents. PubMed: Reaction of the tobacco alkaloid myosmine with hydrogen peroxide. PubMed: N-acylation of glucosamine modulates chondrocyte growth, proteoglycan synthesis, and gene expression. PubMed: Synthesis and anticonvulsant evaluation of N-substituted-isoindolinedione derivatives. PubMed: Trace detection of glycolic acid by electrophore labeling gas chromatography-electron capture mass spectrometry. PubMed: Acetylated, propionylated or butyrylated starches raise large bowel short-chain fatty acids preferentially when fed to rats. PubMed: Synthesis of N4-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)-L-asparagine analogues. n-Butyramide, 3-chloropropionamide, 3-aminopropionamide, and isovaleramide analogues. PubMed: AMACE1: versatile aminoacetamide electrophore reagent. PubMed: Side chain modified 5-deazafolate and 5-deazatetrahydrofolate analogues as mammalian folylpolyglutamate synthetase and glycinamide ribonucleotide formyltransferase inhibitors: synthesis and in vitro biological evaluation. PubMed: Detection of phenolalkylamines by capillary column gas chromatography-negative chemical ionization mass spectrometry. PubMed: Partial reversal of the acetaldehyde and butyraldehyde oxidation reactions catalysed by aldehyde dehydrogenases from sheep liver.