gallium maltolate
gallium, tris[3-(hydroxy-\KO)-2-methyl-4H-pyran-4-onato-\KO4]- (OC-6-21)
Identification
| Name | gallium maltolate |
| CAS Number | 108560-70-9 |
| FDA UNII | 17LEI49C2G |
| Molecular Formula | C18 H15 Ga O9 |
| Molecular Weight | 445.03335000 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | skin conditioning |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | cosmetic ingredient for skin conditioning |
| Recommendation for gallium maltolate usage levels up to | not for fragrance use. |
| Recommendation for gallium maltolate flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
gallium, tris[3-(hydroxy-\KO)-2-methyl-4H-pyran-4-onato-\KO4]- (OC-6-21)
tris(3-
hydroxy-2-methyl-4H-pyran-4-onato)gallium(III)
PubMed:
Serum and tissue concentrations of gallium after oral administration of gallium nitrate and gallium maltolate to neonatal calves.
PubMed:
Gallium maltolate as an alternative to macrolides for treatment of presumed Rhodococcus equi pneumonia in foals.
PubMed:
Interaction of the anticancer gallium(III) complexes of 8-hydroxyquinoline and maltol with human serum proteins.
PubMed:
Gallium maltolate inhibits human cutaneous T-cell lymphoma tumor development in mice.
PubMed:
Comparison of the antimicrobial activities of gallium nitrate and gallium maltolate against Mycobacterium avium subsp. paratuberculosis in vitro.
PubMed:
In vitro susceptibility of equine-obtained isolates of Corynebacterium pseudotuberculosis to gallium maltolate and 20 other antimicrobial agents.
PubMed:
Efficacy of gallium maltolate against Lawsonia intracellularis infection in a rabbit model.
PubMed:
Pharmacokinetics of gallium maltolate in Lawsonia intracellularis-infected and uninfected rabbits.
PubMed:
Reduction in absorption of gallium maltolate in adult horses following oral administration with food: chemistry and pharmacokinetics.
PubMed:
Synchrotron X-ray fluorescence microscopy of gallium in bladder tissue following gallium maltolate administration during urinary tract infection.
PubMed:
Successful treatment of refractory postherpetic neuralgia with topical gallium maltolate: case report.
PubMed:
Antimicrobial activity of gallium maltolate against Staphylococcus aureus and methicillin-resistant S. aureus and Staphylococcus pseudintermedius: An in vitro study.
PubMed:
Evaluation of the efficacy of gallium maltolate for chemoprophylaxis against pneumonia caused by Rhodococcus equi infection in foals.
PubMed:
Hepatocellular carcinoma detection by gallium scan and subsequent treatment by gallium maltolate: rationale and case study.
PubMed:
Evaluation of the effect of gallium maltolate on fecal Salmonella shedding in cattle.
PubMed:
Pharmacokinetics of gallium maltolate after intragastric administration in adult horses.
PubMed:
Pharmacokinetics of an orally administered methylcellulose formulation of gallium maltolate in neonatal foals.
PubMed:
In vitro antimicrobial activity of gallium maltolate against virulent Rhodococcus equi.
PubMed:
Gallium maltolate: safety in neonatal foals following multiple enteral administrations.
PubMed:
A novel gallium compound synergistically enhances bortezomib-induced apoptosis in mantle cell lymphoma cells.
PubMed:
In vitro activity of gallium maltolate against Staphylococci in logarithmic, stationary, and biofilm growth phases: comparison of conventional and calorimetric susceptibility testing methods.
PubMed:
Gallium maltolate treatment eradicates Pseudomonas aeruginosa infection in thermally injured mice.
PubMed:
Chemistry and pharmacokinetics of gallium maltolate, a compound with high oral gallium bioavailability.
PubMed:
Pharmacokinetics of gallium maltolate after intragastric administration in neonatal foals.
PubMed:
Development of gallium compounds for treatment of lymphoma: gallium maltolate, a novel hydroxypyrone gallium compound, induces apoptosis and circumvents lymphoma cell resistance to gallium nitrate.
PubMed:
Gallium maltolate is a promising chemotherapeutic agent for the treatment of hepatocellular carcinoma.
PubMed:
Antimicrobial activity of gallium against virulent Rhodococcus equiin vitro and in vivo.
PubMed:
Gallium in cancer treatment.
PubMed:
Gateways to clinical trials.
PubMed:
Gallium and other main group metal compounds as antitumor agents.
PubMed:
Gateways to clinical trials.