gallium maltolate

gallium, tris[3-(hydroxy-\KO)-2-methyl-4H-pyran-4-onato-\KO4]- (OC-6-21)

CAS: 108560-70-9 C18 H15 Ga O9 MW: 445.03335000

Identification

Namegallium maltolate
CAS Number108560-70-9
FDA UNII17LEI49C2G
Molecular FormulaC18 H15 Ga O9
Molecular Weight445.03335000

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesskin conditioning

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorycosmetic ingredient for skin conditioning
Recommendation for gallium maltolate usage levels up tonot for fragrance use.
Recommendation for gallium maltolate flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

gallium, tris[3-(hydroxy-\KO)-2-methyl-4H-pyran-4-onato-\KO4]- (OC-6-21) tris(3- hydroxy-2-methyl-4H-pyran-4-onato)gallium(III) PubMed: Serum and tissue concentrations of gallium after oral administration of gallium nitrate and gallium maltolate to neonatal calves. PubMed: Gallium maltolate as an alternative to macrolides for treatment of presumed Rhodococcus equi pneumonia in foals. PubMed: Interaction of the anticancer gallium(III) complexes of 8-hydroxyquinoline and maltol with human serum proteins. PubMed: Gallium maltolate inhibits human cutaneous T-cell lymphoma tumor development in mice. PubMed: Comparison of the antimicrobial activities of gallium nitrate and gallium maltolate against Mycobacterium avium subsp. paratuberculosis in vitro. PubMed: In vitro susceptibility of equine-obtained isolates of Corynebacterium pseudotuberculosis to gallium maltolate and 20 other antimicrobial agents. PubMed: Efficacy of gallium maltolate against Lawsonia intracellularis infection in a rabbit model. PubMed: Pharmacokinetics of gallium maltolate in Lawsonia intracellularis-infected and uninfected rabbits. PubMed: Reduction in absorption of gallium maltolate in adult horses following oral administration with food: chemistry and pharmacokinetics. PubMed: Synchrotron X-ray fluorescence microscopy of gallium in bladder tissue following gallium maltolate administration during urinary tract infection. PubMed: Successful treatment of refractory postherpetic neuralgia with topical gallium maltolate: case report. PubMed: Antimicrobial activity of gallium maltolate against Staphylococcus aureus and methicillin-resistant S. aureus and Staphylococcus pseudintermedius: An in vitro study. PubMed: Evaluation of the efficacy of gallium maltolate for chemoprophylaxis against pneumonia caused by Rhodococcus equi infection in foals. PubMed: Hepatocellular carcinoma detection by gallium scan and subsequent treatment by gallium maltolate: rationale and case study. PubMed: Evaluation of the effect of gallium maltolate on fecal Salmonella shedding in cattle. PubMed: Pharmacokinetics of gallium maltolate after intragastric administration in adult horses. PubMed: Pharmacokinetics of an orally administered methylcellulose formulation of gallium maltolate in neonatal foals. PubMed: In vitro antimicrobial activity of gallium maltolate against virulent Rhodococcus equi. PubMed: Gallium maltolate: safety in neonatal foals following multiple enteral administrations. PubMed: A novel gallium compound synergistically enhances bortezomib-induced apoptosis in mantle cell lymphoma cells. PubMed: In vitro activity of gallium maltolate against Staphylococci in logarithmic, stationary, and biofilm growth phases: comparison of conventional and calorimetric susceptibility testing methods. PubMed: Gallium maltolate treatment eradicates Pseudomonas aeruginosa infection in thermally injured mice. PubMed: Chemistry and pharmacokinetics of gallium maltolate, a compound with high oral gallium bioavailability. PubMed: Pharmacokinetics of gallium maltolate after intragastric administration in neonatal foals. PubMed: Development of gallium compounds for treatment of lymphoma: gallium maltolate, a novel hydroxypyrone gallium compound, induces apoptosis and circumvents lymphoma cell resistance to gallium nitrate. PubMed: Gallium maltolate is a promising chemotherapeutic agent for the treatment of hepatocellular carcinoma. PubMed: Antimicrobial activity of gallium against virulent Rhodococcus equiin vitro and in vivo. PubMed: Gallium in cancer treatment. PubMed: Gateways to clinical trials. PubMed: Gallium and other main group metal compounds as antitumor agents. PubMed: Gateways to clinical trials.