Identification

Namemethyl propionate
IUPACmethyl propanoate
CAS Number554-12-1
EINECS209-060-4
FDA UNIINB21C0D33W
Molecular FormulaC4 H8 O2
Molecular Weight88.10616000
MDL NumberMFCD00009306
Nikkaji NumberJ2.654I
Beilstein1737628
CoE Number415
XlogP30.80 (est)

Regulatory

JECFA Food Flavoring141 methyl propionate
DG SANTE Food Flavourings09.134 methyl propionate
FEMA Number2742
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)554-12-1 ; METHYL PROPIONATE
FDA RegulationFDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION

Physical Properties

Appearance colorless clear liquid (est)
Assay 98.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 0.91300 to 0.91800 @ 25.00 °C.
Pounds per Gallon - (est). 7.597 to 7.639
Refractive Index 1.37500 to 1.37900 @ 20.00 °C.
Melting Point -88.00 to -87.00 °C. @ 760.00 mm Hg
Boiling Point 79.00 to 80.00 °C. @ 760.00 mm Hg, 28.00 to 29.00 °C. @ 100.00 mm Hg
Vapor Pressure 142.778000 mmHg @ 25.00 °C. (est)
Vapor Density 3.0 ( Air = 1 )
Flash Point 43.00 °F. TCC ( 6.11 °C. )
logP (o/w) 0.840
Soluble in alcohol
Insoluble in water
Similar Items note

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesperfuming agents

Organoleptic Properties

Odor Strength medium
Substantivity 4 hour(s) at 100.00 %
Odor Description
at 100.00 %.
Strawberry, Banana, Apple
Odor sample from Fritzsche Dodge & Olcott, Inc.
Taste Description fruity ethereal juicy fruit rummy banana

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Human Experience2 % solution: no irritation or sensitization.
Oral/Parenteral Toxicityoral-rat LD50 5000 mg/kg
Dermal Toxicityskin-rabbit LD50 > 5000 mg/kg
Inhalation Toxicityinhalation-mouse LC50 27000 mg/m3

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavor and fragrance agents
RIFM Fragrance Material Safety AssessmentSearch
Recommendation for methyl propionate usage levels up to2.0000 % in the fragrance concentrate.
Maximised Survey-derived Daily Intakes (MSDI-EU)9.30 (μg/capita/day)
baked goods-
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum-
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

Alfrebro LLC/ Archer Daniels Midland Company

Let's get reacquainted

Building great taste with aroma chemicals, extracts, and distillates

View All Website 513-539-7373 sforbis@alfrebro.com

Beijing Lys Chemicals Co, LTD.

From Grams to Tons

Fine chemical high-tech company which contains R&D, production, and sales.

View All Website 86-10-68418738 jiayanyong@lyschem.com

Glentham Life Sciences Ltd

The Chemical, Biochemical & Research Essentials Supplier

Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK.

View All Website +44 (0) 1225 667798 info@glentham.com

FRUTAROM USA INC,

Flavor & Specialty Ingredients

Your preferred partner for flavour and fragrance success.

View All Website +44 (0) 1429 863 222 Sales.IFFIngredients@iff.com

Lluch Essence S.L.

A family company dedicated to sales and distribution

Flexibility, availability, price and quality.

View All Website 34 93 379 38 49 web@lluche.com

M&U International LLC

Steady supply & demand

Meeting customers increasing demands at home as well as abroad.

View All Website 908-359-9000 sales@mu-intel.com

Penta International Corporation

Chemistry innovation

At Penta, our products and services help businesses do business better.

View All Website (973) 740-2300 lisaa@pentamfg.com

Sigma-Aldrich

Complete Supply Chain

The perfect blend of products and services that bring your creativity to life.

View All Website 800-244-1173 ff@sial.com

Sunaux International

Buy With Confidence

We have industry leading processes and procedures to ensure nothing but the most reliable product.

View All Website 0512-57995626 johnjft@sunaux.com

Taytonn ASCC Pte Ltd

Supplying Asia Pacific

We fully understand the demands of the F&F industry and we endeavour to supply quality products, with ready availability and a personalised service.

View All Website + 65 - 6861 8113 info@taytonnascc.com

TCI AMERICA

Moving Your Chemistry Forward

We continuously strive to advance our technology.

View All Website 1-800-423-8616 Sales-US@TCIchemicals.com;

Ernesto Ventós S.A.

Leaders in essence

We employ our five senses to do our job well.

View All Website +1 856 226 7501 info@ventos.com

Vigon International

Passion for Simplicity

Manufacturer and supplier of high quality flavor and fragrance ingredients.

View All Website 570-476-6300 sales@vigon.com

WholeChem, LLC

Connecting Innovators To the Building Blocks Of the Universe

Custom manufacturer and distributor of specialty ingredients. We make global local.

View All Website +1 (262) 995.8668 info@wholechem.com

Potential Uses

FR apple FR banana FL cheese cheddar cheese FR coffee FR currant black currant FL durian feyoa FL brandy grape brandy FR guava FR melon FR papaya FL brandy plum brandy FR strawberry

Natural Occurrence

apple fruit PMC banana fruit brandy apple brandy PMC cheese cheddar cheese PMC coffee PMC honey PMC pork cooked pork PMC strawberry wild strawberry fruit

Synonyms

methyl propanoate nat. methyl propionate methyl propionate, natural methyl propylate methylpropanoate methylpropionate propanoic acid methyl ester propanoic acid, methyl ester propionic acid methyl ester propionic acid, methyl ester Info: Volatile Flavor Components in Bogyojosaeng and Suhong Cultivars of Strawberry (Fragaria ananassa Duch.) PubMed: Iridium(I) PNP complexes in the sp³ C-H bond activation of methyl propanoate and related esters. PubMed: Carbonylation of ethene catalysed by Pd(II)-phosphine complexes. PubMed: Synthesis of methyl propanoate by Baeyer-Villiger monooxygenases. PubMed: Mikania glomerata: Phytochemical, Pharmacological, and Neurochemical Study. PubMed: Crystal structures of (μ2-η(2),η(2)-4-hydroxybut-2-yn-1-yl 2-bromo-2-methylpropanoate-κ(4) C (2),C (3):C (2),C (3))bis[tricarbonylcobalt(II)](Co-Co) and [μ2-η(2),η(2)-but-2-yne-1,4-diyl bis(2-bromo-2-methyl-propanoate)-κ(4) C (2),C (3):C (2),C (3)]bis[tricarbonylcobalt(II)](Co-Co). PubMed: Theoretical study of the rate constants for the hydrogen atom abstraction reactions of esters with (•)OH radicals. PubMed: Reactions of Cl atoms with alkyl esters: kinetic, mechanism and atmospheric implications. PubMed: Endophytic fungi producing of esterases: evaluation in vitro of the enzymatic activity using pH indicator. PubMed: Elucidation of the upper pathway of alicyclic musk Romandolide degradation in OECD screening tests with activated sludge. PubMed: Applicability of non-halogenated methyl propionate to microencapsulation. PubMed: Theoretical and kinetic study of the hydrogen atom abstraction reactions of esters with H(O.)2 radicals. PubMed: Gas signatures from Escherichia coli and Escherichia coli-inoculated human whole blood. PubMed: Redirecting catalysis from proteolysis to perhydrolysis in subtilisin Carlsberg. PubMed: Determination of odor release in hydrocolloid model systems containing original or carboxylated cellulose at different pH values using static headspace gas chromatographic (SHS-GC) analysis. PubMed: High-temperature measurements of the reactions of OH with small methyl esters: methyl formate, methyl acetate, methyl propanoate, and methyl butanoate. PubMed: Solvent- or temperature-controlled diastereoselective aldol reaction of methyl phenylacetate. PubMed: Transferable force field for carboxylate esters: application to fatty acid methylic ester phase equilibria prediction. PubMed: Benzyl 2-{4-[2-(4-chloro-benzoyl-amino)-eth-yl]phen-oxy}-2-methyl-propionate. PubMed: Volatile compounds responsible for aroma of Jutrzenka liquer wine. PubMed: Atmospheric chemistry of two biodiesel model compounds: methyl propionate and ethyl acetate. PubMed: Characterization of odor-active compounds of various cherry wines by gas chromatography-mass spectrometry, gas chromatography-olfactometry and their correlation with sensory attributes. PubMed: The first example of main-chain cyclic azobenzene polymers. PubMed: An engineered methanogenic pathway derived from the domains Bacteria and Archaea. PubMed: Effect of nitroethane, dimethyl-2-nitroglutarate and 2-nitro-methyl-propionate on ruminal methane production and hydrogen balance in vitro. PubMed: Absolute configuration of methyl isoeichlerialactone. PubMed: tert-Butyl 2-(4-chloro-benzo-yl)-2-methyl-propanoate. PubMed: tert-Butyl 2-benzoyl-2-methyl-propanoate. PubMed: On the low volatility of cyclic esters: an infrared spectroscopy comparison between dimers of gamma-butyrolactone and methyl propionate. PubMed: Effect of methylene spacers on the spectral, electrochemical, and structural properties of bis(4,4'-disubstituted-2,2'-bipyridyl) ruthenium(II) dye analogues. PubMed: Controllable nanostructured surface modification on quantum dot for biomedical application in aqueous medium. PubMed: Diphenylphosphine containing macromolecules in the methoxycarbonylation of ethene: the effect of macromolecular architecture on the selectivity of the reaction. PubMed: Theoretical studies on structures and spectroscopic properties of self-assembled bis(2,4,8,10-tetramethyl-9-methoxycarbonylethyldipyrrin-3-yl)methane with Co(II). PubMed: Polymer producing palladium complexes of unidentate phosphines in the methoxycarbonylation of ethene. PubMed: Poly[(μ(2)-2-hydr-oxy-2-methyl-propionato-κO,O:O)(μ(2)-2-hydr-oxy-2-methyl-propionato-κO:κO)dioxido-uranium(VI)]. PubMed: Facile functionalization of multilayer fullerenes (carbon nano-onions) by nitrene chemistry and "grafting from" strategy. PubMed: In-situ polymerization at the interfaces of micelles: a "grafting from" method to prepare micelles with mixed coronal chains. PubMed: New polyethylene macroinitiators and their subsequent grafting by atom transfer radical polymerization. PubMed: Kinetic studies of fusarium solani pisi cutinase used in a gas/solid system: transesterification and hydrolysis reactions. PubMed: One- and two-dimensional direct chiral liquid chromatographic determination of mixtures of diclofop-Acid and diclofop-methyl herbicides. PubMed: 2-Methyl-2-(4-nitro-phen-oxy)propanoic acid. PubMed: Methyl 3-(4-{6-methyl-4-[3-(trifluoro-meth-yl)phen-yl]pyridazin-3-yl-oxy}phen-yl)propanoate. PubMed: Opposite signs of capacitive microsensor signals upon exposure to the enantiomers of methyl propionate compounds. PubMed: Effects of short-chain nitrocompounds against Campylobacter jejuni and Campylobacter coli in vitro. PubMed: Correlating volatile compounds, sensory attributes, and quality parameters in stored fresh-cut cantaloupe. PubMed: Solvent as a competitive inhibitor for Candida antarctica lipase B. PubMed: Ester versus polyketone formation in the palladium-diphosphine catalyzed carbonylation of ethene. PubMed: Isolation and characterization of dihydromonacolin-MV from Monascus purpureus for antioxidant properties. PubMed: Recognition of small polar molecules with an ionic crystal of alpha-Keggin-type polyoxometalate with a macrocation. PubMed: NMR spectroscopy and MALDI-TOF MS characterisation of end-functionalised PVP oligomers prepared with different esters as chain transfer agents. PubMed: Behaviour of [PdH(dppe)2]X (X=CF3SO3-, SbF6-, BF4-) as proton or hydride donor: relevance to catalysis. PubMed: Effect of oil substitution in chiral microemulsion electrokinetic chromatography. PubMed: Solid/gas biocatalysis: an appropriate tool to study the influence of organic components on kinetics of lipase-catalyzed alcoholysis. PubMed: Alcoholysis catalyzed by Candida antarctica lipase B in a gas/solid system: effects of water on kinetic parameters. PubMed: Alcoholysis of acylpalladium(II) complexes relevant to the alternating copolymerization of ethene and carbon monoxide and the alkoxycarbonylation of alkenes: the importance of Cis-coordinating phosphines. PubMed: Total synthesis of Elisabethin A: intramolecular Diels-Alder reaction under biomimetic conditions. PubMed: Determination of PNU-248686A, a novel matrix metalloproteinase inhibitor, in human plasma by liquid chromatography-tandem mass spectrometry, following protein precipitation in the 96-well plate format. PubMed: Water plays a different role on activation thermodynamic parameters of alcoholysis reaction catalyzed by lipase in gaseous and organic media. PubMed: Gas-phase reactivity of the O=P(OCH3)2+ phosphonium ion with aliphatic esters in a quadrupole ion trap. Spontaneous elimination of ketenes. PubMed: Alcoholysis catalyzed by Candida antarctica lipase B in a gas/solid system obeys a Ping Pong Bi Bi mechanism with competitive inhibition by the alcohol substrate and water. PubMed: Identification and effects of interaction phytotoxic compounds from exudate of Cistus ladanifer leaves. PubMed: Stereoselective synthesis of iso-dolaproine via dynamic kinetic resolution. PubMed: Systematic studies on synthesis, structural elucidation, and biological evaluation of A-ring diastereomers of 2-methyl-1alpha,25-dihydroxyvitamin D(3) and 20-epi-2-methyl-1alpha,25-dihydroxyvitamin D(3). PubMed: Syntheses of carbon-11 labeled piperidine esters as potential in vivo substrates for acetylcholinesterase. PubMed: [Interpretation of the resonance Raman spectrum of cytochrome P-450]. PubMed: Determination of remifentanil, an ultra-short-acting opioid anesthetic, in rat blood by high performance liquid chromatography with ultraviolet detection. PubMed: Methyl propionate radical cation. PubMed: Seed Dormancy in Red Rice (Oryza sativa) (IX. Embryo Fructose-2,6-Bisphosphate during Dormancy Breaking and Subsequent Germination). PubMed: Purification and characterization of a carboxylesterase from Pseudomonas sp. KWI-56. PubMed: Determination of remifentanil in human and dog blood by HPLC with UV detection. PubMed: Seed Dormancy in Red Rice : VIII. Embryo Acidification during Dormancy-Breaking and Subsequent Germination. PubMed: Gas phase transesterification reactions catalyzed by lipolytic enzymes. PubMed: Enhancement of the CDC ovitrap with hay infusions for daily monitoring of Aedes aegypti populations. PubMed: The effect of short term feeding of the antioxidant triethyleneglycol-bis-3(3-tert-butyl-4-hydroxy-5-methyl)propionate on serum thyrotropin and thyroid hormones in the male rat. PubMed: Effect of peroxisome proliferators on intrachromosomal and interchromosomal recombination in yeast. PubMed: Species differences in the chirality of the carbonyl reduction of [14C] fenofibrate in laboratory animals and humans. PubMed: [Synthesis of carbon-14 labeled 1-acetoxyethyl 2-(2-fluoro-4-biphenyl)propionate (14C-FP 83)]. PubMed: Observations concerning the nature of sites of anaesthetic action in Gammarus. PubMed: Factors affecting oviposition site preference by Toxorhynchites splendens in the laboratory. PubMed: Purification and characterization of 3-hydroxyisobutyrate dehydrogenase from rabbit liver. PubMed: Local anesthetic action of carboxylic esters: evidence for the significance of molecular volume and for the number of sites involved. PubMed: Properties of the Mg-Protoporphyrin IX Monomethyl Ester (Oxidative) Cyclase System. PubMed: Ethyl acrylate-induced gastric toxicity. II. Structure-toxicity relationships and mechanism. PubMed: Proposed structure for the noncovalently associated heme prosthetic group of dissimilatory nitrite reductases. Configuration of substituents of acrylochlorin. PubMed: Evaluation of selected hypolipidemic agents for the induction of peroxisomal enzymes and peroxisome proliferation in the rat liver. PubMed: Induction of hamster hepatic peroxisomal beta-oxidation and peroxisome proliferation-associated 80000 mol. wt. polypeptide by hypolipidemic drugs. PubMed: Uricosuric effect of fenofibrate in healthy volunteers. PubMed: [Chemistry of phenoxyacetic acid esters of oxyalkyltheophyllines and 1-(theophyllin-7-yl)-ethyl-2-[2-(p-chlorophenoxy)-2-methyl-propionate] (etofylline clofibrate), a novel antilipaemic agent (author's transl)]. PubMed: Volatiles produced by microorganisms isolated from refrigerated chicken at spoilage. PubMed: Antilipidemic drugs. Part 4: The metabolic fate of the hypolipidemic agent isopropyl-[4'-(p-chlorobenzoyl)-2-phenoxy-2-methyl]-protionate (LF 178) in rats, dog and man. PubMed: Antilipidemic drugs. Part 3: On the synthesis of 14C-radiolabelled isopropyl-[4'-chlorobenzoyl)-2-phenoxy-2-methyl]-propionate (LF-178). PubMed: Antilipidemic drugs. Part 2: Experimental study of a new potent hypolipidemic drug, isopropyl-[4'-(p-chlorobenzoyl)-2-phenoxy-2-methyl]-propionate (LF178). PubMed: Antilipidemic drugs. Part 6: LF 178 in man. A preliminary note on a multicenter investigation bearing on 393 subjects with pure or mixed forms of hyperlipidemia. PubMed: Atilipidemic drugs. Part 5: Evaluation of the hypolipidemic effect of LF 178 in 191 patients affected by the atherogenic form of endogenous hyperlipoproteinemia (types IIa, IIb and IV). PubMed: The oxidation products of crude mesobilirubinogen. PubMed: Influence of ethyl-2 [chlorophenoxy]--2--methyl propionate [atromid--s] on liposoluble vitamins.